tumour necrosis factor receptor - JNK signalling - integrates apoptotic functions from Eigerwith signaling from apical polarity determinants to induce JNK-dependent cell death or tumour growth
Gene model reviewed during 5.45
Interacts with egr, Traf6/TRAF2 and veli (via PDZ domain).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\grnd using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\grnd in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: grnd CG10176
Named 'grindelwald' ('grnd'), after a village at the foot of Eiger, a Swiss mountain that lent its name to the unique Drosophila TNF, 'Egr'.