perd, perdido
conserved multi-domain transmembrane receptor required cell autonomously for myotubes to recognize their tendon cell targets - signals through the intracellular adaptor Grip in a conserved molecular pathway
Please see the GBrowse view of Dmel\kon or the JBrowse view of Dmel\kon for information on other features
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\kon using the Feature Mapper tool.
Comment: reported as dorsal vessel specific anlage
At stage 12, kon transcripts were present in three to four cells per hemisegment, consistent with being longitudinal glial cell lineage daughter cells.
GBrowse - Visual display of RNA-Seq signals
View Dmel\kon in GBrowse 2
2-53
2-53
2-53.3
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: perd CG10275
Source for identity of: kon CG10275
Some ventral muscles fail to reach their attachment sites and instead form rounded multinucleated myotubes.
kon is required for myotubes to recognise their tendon cell targets and to establish a stable connection during muscle development.
Named "perdido" ("lost" in Spanish) because muscles fail to find their attachment sites in mutant embryos.
The gene is named "perdido", meaning "lost" in Spanish, since the morphology of muscles in mutant embryos indicates that they are not attached to the epidermal tendon cells.
The gene is named "kon-tiki" after the raft on which explorer Thor Heyerdahl sailed to Polynesia.
