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Gene Dmel\CG10492

General Information
Symbol	Dmel\CG10492	Species	D. melanogaster
Name		Annotation symbol	CG10492
Feature type	protein_coding_gene	FlyBase ID	FBgn0032748
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	TU37B1
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	37B12-37B12	Sequence location	2L:19,054,078..19,058,821 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10492 (FBgn0032748). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, CCHC-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628001_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG10492. Gene sequence location is 2L:19054078..19058821.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 37B12-37B12   Limits computationally determined from genome sequence between P{lacW}l(2)37Dbk16106&P{lacW}Catsupk05424 and P{lacW}Ddck02104
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10492 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 DGC clone appears problematic: incomplete CDS (GH15748)
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10492-RA FBtr0081148  NM_136093   4507   810 CG10492-RB FBtr0113043  NM_001103709   4096   810
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10492-PA   FBpp0080692   89.1   810   7.58     NP_609937   AAF53750 CG10492-PB   FBpp0111956   89.1   810   7.58     NP_001097179   ABV53694
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA203104   AA390414   AA390958   AA391016   AA392319   AA438710   AA439912   AA440488   AA539634   AA540443   AA540859   AA697642   AA949595   AA949742   AE014134 AAF53750   AE014134 ABV53694   AI257283   AI257421   AI292764   AI294579   AI531742   AW941816   AW942984   AY058390 AAL13619   AY075400 AAL68230   BF490492   BF495348   BF495357   BF502565   BF505113   BG634803   BG637783   BG637980   BG639361   BG639586   BG641103   BG641249   BI234548   BI356176   BI371527   BI374651   BI639061   CK661198   CK662491   CL526186   CO185389   CO186681   CO272028   CO272029   CO272030   CO272031   CO272032   CO274487   CO274850   CO274851   CO274852   CO274853   CO274854   CO274855   CO274856   CO274857   CO282853   CO289706   CO300763   CO301833   CO318833   CO324335   CO325073   CO331048   CO331452   CO332072   EC052236   EC052776   EC052784   EC054738   EC057418   EC067598   EC077345   EC079856   EC080274   EC083156   EC090495   EC194887   EC196328   EC196329   EC199226   EC200251   EC200827   EC207713   EC209459   EC211398   EC215842   EC216559   EC217723   EC219100   EC225099   EC228130   EC230706   EC234070   EC235340   EC247293   ES690304   GH950034   GH952560   GH958681   GH959698   GH971705
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VJ08 Q95U09
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary  (598.8) Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary  598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    280.975 Larval Midgut    85 Larval Hindgut    108.2 Larval Malpighian Tubules    98.7 Larval Fat Body    74 Larval Salivary Gland    219.8 Larval Trachea    205.575 Larval Carcass    123.05 Adult Head    127.7 Adult Eye    140.5 Adult Brain    295 Adult Thoracic-Abdominal Ganglion    227.9 Adult Crop    150.9 Adult Midgut    83.1 Adult Hindgut    111.9 Adult Malpighian Tubules    112.2 Adult Fat Body    124.9 Adult Salivary Gland    144.8 Adult Heart    101.05 Adult VirginFemale Spermatheca    209.1 Adult InseminatedFemale Spermatheca    202.8 Adult Ovary    598.8 Adult Testis    23.5 Adult Male Accessory Gland    148.2 Adult Carcass    100 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    127.7   NA  Eye    140.5   NA  Brain    295   280.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    227.9   NA  Crop    150.9   85  Midgut    83.1   108.2  Hindgut    111.9   98.7  Malpighian Tubules    112.2   74  Fat Body    124.9   219.8  Salivary Gland    144.8   NA  Heart    101.05   205.575  Trachea    NA   NA  VirginFemale Spermatheca    209.1   NA  InseminatedFemale Spermatheca    202.8   NA  Ovary    598.8   NA  Testis    23.5   NA  Male Accessory Gland    148.2   123.05  Carcass    100 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (53) central nervous system, larvae L3  26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (82) ovary, mated 4-day female  (87) testis, mated 4-day male  (50) accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (53) central nervous system, larvae L3  26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (82) ovary, mated 4-day female  (87) testis, mated 4-day male  (50) accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    53 central nervous system, larvae L3    26 central nervous system, pupae P8    20 head, virgin 1-day female    10 head, virgin 4-day female    12 head, virgin 20-day female    9 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    5 digestive system, 4-day adult    10 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    13 fat body, pupae P8    9 carcass, larvae L3 wandering    14 carcass, 1-day adult    8 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    82 ovary, mated 4-day female    87 testis, mated 4-day male    50 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (90) embryo 02-04hr  (88) embryo 04-06hr  (31) embryo 06-08hr  (31) embryo 08-10hr  (35) embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr  (35) embryo 16-18hr  (27) embryo 18-20hr    17 embryo 20-22hr  (39) embryo 22-24hr  (29) larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr  26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day  (28) adult male 30day  (30) adult female 01day  (35) adult female 05day  (53) adult female 30day  (56) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (90) embryo 02-04hr  (88) embryo 04-06hr  31 embryo 06-08hr  31 embryo 08-10hr  (35) embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr  (35) embryo 16-18hr  27 embryo 18-20hr    17 embryo 20-22hr  (39) embryo 22-24hr  29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr  26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day  28 adult male 30day  30 adult female 01day  (35) adult female 05day  (53) adult female 30day  (56) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    90 embryo 02-04hr    88 embryo 04-06hr    31 embryo 06-08hr    31 embryo 08-10hr    35 embryo 10-12hr    20 embryo 12-14hr    24 embryo 14-16hr    35 embryo 16-18hr    27 embryo 18-20hr    17 embryo 20-22hr    39 embryo 22-24hr    29 larva L1    13 larva L2    7 larva L3 12hr old    7 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    15 white prepupae new    15 white prepupae 12hr    20 white prepupae 24hr    26 pupae 2d postWPP    22 pupae 3d postWPP    15 pupae 4d postWPP    16 adult male 01day    20 adult male 05day    28 adult male 30day    30 adult female 01day    35 adult female 05day    53 adult female 30day    56 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167  (27) embryonic S1  (29) embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9  (30) wing disc ML-DmD16-c3  (29) wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1  (30) CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS  (34) ovary OSC  26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167  27 embryonic S1  29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9  30 wing disc ML-DmD16-c3  29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1  30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS  (34) ovary OSC  26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    14 embryonic 1182-4H    20 embryonic GM2    24 embryonic Kc167    27 embryonic S1    29 embryonic S3    18 leg disc CME L1    17 wing disc CME-W2    18 wing disc ML-DmD8    17 wing disc ML-DmD9    30 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    9 wing disc ML-DmD32    17 haltere disc ML-DmD17-c3    23 eye-antennal disc ML-DmD11    22 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    30 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    23 ovary fGS/OSS    34 ovary OSC    26 ovary OSS    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (27) cold shock, 4-day adult    20 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult  (30) Cadmium 100 mM 48 hrs, 4-day adult  (69) Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult  (41) Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3  (71) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (58) Caffeine 25 mg/ml 48 hrs, 4-day adult  (35) Paraquat 5 mM 48 hrs, 4-day adult  (55) Paraquat 10 mM 48 hrs, 4-day adult  (51) Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  27 cold shock, 4-day adult    20 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult  30 Cadmium 100 mM 48 hrs, 4-day adult  (69) Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult  (41) Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3  (71) Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (58) Caffeine 25 mg/ml 48 hrs, 4-day adult  (35) Paraquat 5 mM 48 hrs, 4-day adult  (55) Paraquat 10 mM 48 hrs, 4-day adult  (51) Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    27 cold shock, 4-day adult    20 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    30 Cadmium 100 mM 48 hrs, 4-day adult    69 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    41 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    71 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    58 Caffeine 25 mg/ml 48 hrs, 4-day adult    35 Paraquat 5 mM 48 hrs, 4-day adult    55 Paraquat 10 mM 48 hrs, 4-day adult    51 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032748 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10492-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 CG10492GD5326 viable CG10492EY10125 Sterility Allele fertile CG10492EY10125 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG10492GD5326 visible, with Scer\GAL4pnr-MD237 CG10492GD5326 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG10492GD5326 trichogen cell, with Scer\GAL4pnr-MD237 CG10492GD5326
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG10492 Class Mutagen Stocks Known lesion CG10492DG02512 P-element activity 2 -- CG10492EY10125 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10492 Class Mutagen Stocks Known lesion CG10492GD5326 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10492B6 in vitro construct - genomic fragment 0 Yes CG10492NIG.10492R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6042 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5326} NA P{NIG.10492R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG10492EY10125 NA miscellaneous insertions P{wHy}CG10492DG02512 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR001878 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR001878 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10492 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0032748
Orthologs
OrthoDB Orthologs (24) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG67PXRZ Dipteran inclusive ortholog search EOG62562G Insect inclusive ortholog search EOG6HQCF6 Arthropod inclusive ortholog search EOG6RXWG3 Metazoa inclusive ortholog search EOG64N9M4
Orthologs in Drosophila Species (EOG67PXRZ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG10492     Drosophila simulans   Dsim\GD24179 Y   Drosophila sechellia   Dsec\GM13599     Drosophila pseudoobscura pseudoobscura   Dpse\GA30005
Orthologs in non-Drosophila Dipterans (EOG62562G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014074   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014622   Anopheles gambiae Malaria mosquito  Agam\AGAP009083   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802319
Orthologs in non-Dipteran Insects (EOG6HQCF6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46144   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006931   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15066   Atta cephalotes Leafcutter ant  Acep\ACEP27140   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17314   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14818   Linepithema humile Argentine ant  Lhum\LH16945   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17984   Solenopsis invicta Red fire ant  Sinv\SINV23596   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009887   Bombyx mori Silkmoth  Bmor\BGIBMGA003209   Pediculus humanus Human body louse  Phum\PHUM163860   Tribolium castaneum Red flour beetle  Tcas\TC014287
Orthologs in non-Insect Arthropods (EOG6RXWG3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW022109
Orthologs in non-Arthropod Metazoa (EOG64N9M4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018551gn   Danio rerio Zebrafish  Drer\ENSDARG00000073838
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (1) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24179
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	17640 y1 w67c23; P{EPgy2}CG10492EY10125 20562 y1 w67c23; P{wHy}CG10492DG02512/SM6a
Kyoto	114601 yd2 w1118 P{ey-FLP.N}2; P{wHy}CG10492DG02512 P{neoFRT}40A/CyO y+
VDRC	v12356 w1118 P{GD5326}v12356
Genomic Clones ( 1 )
	BACR04C20 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 90 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH15748 LD29741
Other clones	DPiM_LD29741
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04341 AT04354 AT07280 AT18235 AT26973 AT31151 HL02921 LD09316 LD09940 LD11791 LD13046 LD13213 LD14611 LD17908 LD19936 LD20686 LD29549 LP05595 LP05780 LP06078 LP20433 LP22750 RE30264 RE42261 RE58438 RE62294 SD12348 SD12548 SD21506
Other clones	1881 12774 38593 45281 55435 58148 65908 67428 76077 98511 145465 175145 194526 272983 274138 274474 CK01.5C.G10 CK01.24D.G2 CK01.91D.B4 EC052236 EC052776 EC052784 EC054738 EK008958 EK022143 EK071838 EK105645 EK105649 EK105653 EK105657 EK105661 EK114249 EK115701 EK115704 EK115707 EK115710 EK115713 EK115716 EK115719 EK115722 EK161449 EK179347 EK182260 EK193248 EK195525 EK274338 EK297344 EK299825 EK302440 LD03609 LD11155 LP07987 RP004026659 RP004143195 RP004177649 RP004408490 RP004554022 SD02990
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032748 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35177
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG10492 anon-37B-1 (FlyBase, 1996-)
Additional comments	Source for merge of CG10492 anon-37B-1 was sequence comparison (date:010517). (FlyBase, 1996-)
Other Comments
	Located between coordinates -62.4 and -57.8. (Stathakis et al., 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136093 NM_001103709 RefSeq (Proteins) • NP_609937 NP_001097179 DDBJ / EMBL / GenBank • AA949742 AAF53750 AAL13619 AAL68230 ABV53694 AI292764 AW941816 AW942984 AY058390 AY075400 CL526186 Entrez Gene - A searchable database of RefSeq genes. • 35177 UniProtKB/TrEMBL • Q9VJ08 Q95U09
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0032748 DRSC - Results from RNAi screens. • FBgn0032748 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032748 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10492-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032748 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35177 modMine - Data generated by the modENCODE project. • FBgn0032748
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-37B-1   B1 (McCrady and Tolin, 1994) CG10492 (McCrady and Tolin, 1994, Japanese National Institute of Genetics, 2012.5.21) TU37B1 (Wright, 1996, Stathakis et al., 1995, ) TuB1 (Thor et al., 1999)
Name Synonym	transcription unit 37B1 (Stathakis et al., 1995)
Secondary FlyBase IDs
	FBgn0005567
References ( 16 )
Research paper	Thor et al., 1999, Nature 397(6714): 76--80 A LIM-homeodomain combinatorial code for motor-neuron pathway selection. [FBrf0105986] Wright, 1996, J. Hered. 87(3): 175--190 The Wilhelmine E. Key 1992 Invitational lecture. Phenotypic analysis of the Dopa decarboxylase gene cluster mutants in Drosophila melanogaster. [FBrf0089206] Stathakis et al., 1995, Genetics 141(2): 629--655 The genetic and molecular organization of the Dopa decarboxylase gene cluster of Drosophila melanogaster. [FBrf0084402] McCrady and Tolin, 1994, J. exp. Zool. 268(6): 469--476 Effects of Ddc cluster lethal alleles on ovary growth, attachment, and egg production in Drosophila. [FBrf0073866]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Gelbart, 2008.3.31, DG.xml DG.xml [FBrf0204101] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection. Deletion Generator Project genomic insertion collection. [FBrf0188490] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]