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Gene Dmel\sNPF

General Information
Symbol	Dmel\sNPF	Species	D. melanogaster
Name	short neuropeptide F precursor	Annotation symbol	CG13968
Feature type	protein_coding_gene	FlyBase ID	FBgn0032840
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	Drm-sNPF-1, 38B.2, sNPF-4, sNPF-3, sNPF-2, sNPF-1, Drm-sNPF, sNPF1, Drm-sNPF-4, Drm-sNPF-3
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	38B1-38B1	Sequence location	2L:20,027,915..20,056,373 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene short neuropeptide F precursor is referred to in FlyBase by the symbol Dmel\sNPF (CG13968, FBgn0032840). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: neuropeptide hormone activity. There is experimental evidence that it is involved in the biological process: larval feeding behavior; regulation of trehalose metabolic process; determination of adult lifespan; positive regulation of cell size; positive regulation of insulin receptor signaling pathway; regulation of glucose metabolic process; positive regulation of ERK1 and ERK2 cascade; multicellular organism growth; adult feeding behavior; positive regulation of multicellular organism growth. 13 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval fat body. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult brain. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1624838_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of sNPF. Gene sequence location is 2L:20027915..20056373.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Dalton et al., 2010, BMC Genomics 11: 541 Carlsson et al., 2010, J. Comp. Neurol. 518(16): 3359--3380 Sequence features BKN31173 HFA02309
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 38B1-38B1   Limits computationally determined from genome sequence between P{lacW}l(2)k10239k10239 and P{lacW}barrk14014
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sNPF for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sNPF-RB FBtr0081327  NM_165316   2447   281
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sNPF-PB   FBpp0080859   32.5   281   8.19     NP_724239   AAN11060
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments	Antibody is to WFGDVNQKPIRSPSLRLRF peptide. (Lee et al., 2004)
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAN11060   AC004364   AY626808 AAU87571   BI611342   BI611468   BI624833   BT001780 AAN71535   CO179172   CO186955   CO187094   CO190624   CO196273   CO261854   CO263189   CO263359   CO264233   CO265051   CO266296   CO269940   CO271992   CO281506   CO283787   CO285944   CO285960   CO286347   CO286727   CO288374   CO288820   CO290173   CO290266   CO290918   CO309883   CO315569   CO315742   CO317228   CO324167   CO324173   CZ466466   CZ470899   CZ470900   CZ471192   CZ489570   CZ489611   CZ490325   EC058044   EC064554   EC066607   EC070184   EC070788   EC072378   EC082654   EC086159   EC194907   EC195903   EC198283   EC203897   EC203929   EC205681   EC206976   EC207342   EC207893   EC210416   EC218734   EC219145   EC219406   EC219593   EC222331   EC229417   EC230604   EC230777   EC231289   EC241891   EC245513   EC246619
UniProtKB/Swiss-Prot	Q9VIQ0
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 14 -- adult stage   nervous system   (Lee et al., 2004) embryonic stage 17   antennal sense organ   (Lee et al., 2004) terminal organ   (Lee et al., 2004) brain   (Lee et al., 2004) embryonic ventral nervous system   (Lee et al., 2004) larval stage   Kenyon cell | faint   (Nässel et al., 2008) protocerebrum | restricted   (Nässel et al., 2008) ventral nerve cord | restricted   (Nässel et al., 2008) embryonic/larval subesophageal ganglion   (Nässel et al., 2008) third instar larval stage   embryonic/larval protocerebrum | anterior & dorsal   (Lee et al., 2004) subesophageal ganglion   (Lee et al., 2004) ventral nerve cord | restricted   (Lee et al., 2004) Comment:expression along midline adult stage   Kenyon cell   (Nässel et al., 2008) adult subesophageal ganglion   (Nässel et al., 2008) optic lobe   (Nässel et al., 2008) adult protocerebrum   (Nässel et al., 2008) adult deuterocerebrum   (Nässel et al., 2008) adult tritocerebrum   (Nässel et al., 2008) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- adult stage   organism   (Lee et al., 2004)
Additional Descriptive Data
	Late embryonic expression of sPNF transcript is observed in the antennomaxillary sense organ, in the posterior of the brain hemispheres, in the fused ventral ganglion, and in bilaterally symmetrical pairs of cells along the ventral midline of the ventral ganglion. In the third instar larval central nervous system, expression is observed in the dorsal anterior region of the protocerebrum of the brain hemispheres, in cells of the subesophageal ganglion, along the ventral midline, and in the thoracic and abdominal segments of the ventral ganglion. (Lee et al., 2004) In situ labelling closely approximates that of antisera labelling in both adults and larvae. At the larval stage approximately 35 neurons per hemisphere, other than the Kenyon cells, are positive for sNPF mRNA. These cells are located dorsally and ventrally and include three strongly labelled neurons with large cell bodies that are probably neurosecretory cells. In each of the thoracic and abdominal neuromeres of the larval ventral nerve cord, three to four lateral cell bodies and one dorso-medial cell body express sNPF transcript. In abdominal neuromeres A7 and A8 there are additional labelled cell bodies with large diameters, and a pair of large dorso-medially located cell bodies expressing sNPF transcript are found in abdominal segment A1. In adults, expression of sNPF transcript is seen in approximately 280 neuronal cell bodies other than the Kenyon cells. The approximately 28 neurons distributed in the adult subesophageal ganglion are located in three bilateral clusters: one cluster close to the esophageal foramen; another ventrolateral in the ganglion; and a third cluster dorsolateral in the ganglion. At the base of the adult optic lobe there are clusters of about 50 small cell bodies distributed anteriorly and posteriorly. Several clusters of sNPF-XR expressing cells are located in the adult dorsal protocerebrum, mostly in the posterior with only approximately four cells located anteriorly. (Nässel et al., 2008)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage 14   ventral nerve cord commissure   (Lee et al., 2004) embryonic stage 14 -- 16   central nervous system   (Lee et al., 2004) peripheral nervous system   (Lee et al., 2004) longitudinal connective   (Lee et al., 2004) embryonic stage 16   ventral midline neuron   (Lee et al., 2004) sensillum | subset   (Lee et al., 2004) larval stage   embryonic/larval brain   (Lee et al., 2004) Kenyon cell   (Nässel et al., 2008) protocerebrum | restricted   (Nässel et al., 2008) ventral nerve cord | restricted   (Nässel et al., 2008) embryonic/larval subesophageal ganglion | restricted   (Nässel et al., 2008) embryonic/larval deuterocerebrum | restricted   (Nässel et al., 2008) lobe system of mushroom body   (Nässel et al., 2008) embryonic/larval optic lobe   (Nässel et al., 2008) pars intercerebralis   (Nässel et al., 2008) mushroom body pedunculus   (Nässel et al., 2008) third instar larval stage   dorsal neurohemal organ   (Lee et al., 2004) ventral nerve cord   (Lee et al., 2004) Comment:abdominal adult stage   medulla   (Lee et al., 2004, Nässel et al., 2008) mushroom body calyx   (Lee et al., 2004) Kenyon cell   (Nässel et al., 2008) adult protocerebrum   (Nässel et al., 2008) adult deuterocerebrum   (Nässel et al., 2008) adult tritocerebrum   (Nässel et al., 2008) adult subesophageal ganglion   (Nässel et al., 2008) lobe system of mushroom body   (Nässel et al., 2008) fan-shaped body   (Nässel et al., 2008) lobula   (Nässel et al., 2008) adult antennal lobe   (Nässel et al., 2008) adult olfactory receptor neuron   (Nässel et al., 2008) in situ Stage Tissue/Position (including subcellular localization) Reference third instar larval stage   neuron of embryonic/larval protocerebrum | anterior & dorsal   • neuronal cell body & axon (Lee et al., 2004) western blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- adult stage   organism   (Lee et al., 2004)
Additional Descriptive Data
	sNPF peptide is found in neurons in the dorsal anterior of the larval prototcerebrum, and in six projecting axons of the thoracic ventral ganglion, and in axons of the descending connectives in the abdominal ventral ganglion. In the adult, sNPF peptide is found in the medulla of the optic lobe and in the calyx of the mushroom body. (Lee et al., 2004) Antisera labelling closely approximates that of in situ labelling in both adults and larvae. sNPF protein appears to be expressed in most of the approximately 600 larval Kenyon cells, and in 190-200 cells of the larval central nervous system, approximately 70 of which are in the brain (including the subesophageal ganglion) and a minimum of 120 in the thoracic and abdominal neuromeres. Three pairs of intensely immunolabelled cells (referred to as LNCs) located dorsally in the protocerebrum are probably neurosecretory cells of the pars lateralis and have axons terminating in the ring gland and anterior aorta. Processes of sNPF immunopositive larval cells are seen in neuropils of the protocerebrum, deutocerebrum, subesophageal ganglion, and most densely in the lobes of the mushroom body. Further processes are seen in the larval optic center, non-glomerular neuropils surrounding the mushroom body lobes, and the pars intercerebralis and lateralis. In the abdominal and thoracic neuromeres of the larval ventral nerve cord, sNPF immunopositive cells are located dorsally, ventrally and laterally. In larval abdominal neuromeres A7 and A8 there are additional immunopositive cell bodies with large diameters, and a pair of large dorso-medially located cell bodies expressing sNPF-XP are found in abdominal segment A1. Two bundles of sNPF immunopositive fibres are found in the ventral ganglia associated with the dors-median and ventro-median tracts. Expression was also seen in two layers of the fan shaped body of the central complex, and in the basal portion of the medulla. Expression within the antennal lobe is located within the olfactory receptor neurons, as determined by coexpression of Scer\GAL4Cha.7.4. (Nässel et al., 2008)
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032840    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032840 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032840 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr  102 embryo 18-20hr  (209) embryo 20-22hr  (374) embryo 22-24hr  (464) larva L1  (434) larva L2  (323) larva L3 12hr old  (111) larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9  (171) white prepupae new  (220) white prepupae 12hr  (225) white prepupae 24hr  (454) pupae 2d postWPP  (1284) pupae 3d postWPP  (467) pupae 4d postWPP  (274) adult male 01day  (393) adult male 05day  (413) adult male 30day  (462) adult female 01day  (164) adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032840 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr  102 embryo 18-20hr  (209) embryo 20-22hr  (374) embryo 22-24hr  (464) larva L1  (434) larva L2  (323) larva L3 12hr old  111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9  (171) white prepupae new  (220) white prepupae 12hr  (225) white prepupae 24hr  (454) pupae 2d postWPP  (1284) pupae 3d postWPP  (467) pupae 4d postWPP  (274) adult male 01day  (393) adult male 05day  (413) adult male 30day  (462) adult female 01day  (164) adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    4 embryo 10-12hr    7 embryo 12-14hr    16 embryo 14-16hr    25 embryo 16-18hr    102 embryo 18-20hr    209 embryo 20-22hr    374 embryo 22-24hr    464 larva L1    434 larva L2    323 larva L3 12hr old    111 larva L3 puffstage 1-2    73 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    171 white prepupae new    220 white prepupae 12hr    225 white prepupae 24hr    454 pupae 2d postWPP    1284 pupae 3d postWPP    467 pupae 4d postWPP    274 adult male 01day    393 adult male 05day    413 adult male 30day    462 adult female 01day    164 adult female 05day    73 adult female 30day    83 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032840    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032840 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult brain. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032840 expression level Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain  (997.3) Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032840 expression level Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain  (997.3) Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    371.6 Larval Midgut    21.4 Larval Hindgut    1.8 Larval Malpighian Tubules    1.8 Larval Fat Body    2.3 Larval Salivary Gland    2.4 Larval Trachea    0.55 Larval Carcass    3.175 Adult Head    310.9 Adult Eye    11.275 Adult Brain    997.3 Adult Thoracic-Abdominal Ganglion    397.7 Adult Crop    2.5 Adult Midgut    7.4 Adult Hindgut    0.8 Adult Malpighian Tubules    2.7 Adult Fat Body    4.1 Adult Salivary Gland    2.9 Adult Heart    1.525 Adult VirginFemale Spermatheca    1.2 Adult InseminatedFemale Spermatheca    1.9 Adult Ovary    0.6 Adult Testis    0.2 Adult Male Accessory Gland    35.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    310.9   NA  Eye    11.275   NA  Brain    997.3   371.6  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    397.7   NA  Crop    2.5   21.4  Midgut    7.4   1.8  Hindgut    0.8   1.8  Malpighian Tubules    2.7   2.3  Fat Body    4.1   2.4  Salivary Gland    2.9   NA  Heart    1.525   0.55  Trachea    NA   NA  VirginFemale Spermatheca    1.2   NA  InseminatedFemale Spermatheca    1.9   NA  Ovary    0.6   NA  Testis    0.2   NA  Male Accessory Gland    35.1   3.175  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_14
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032840 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13968-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Other Phenotypes Allele decreased cell size sNPFc00448 decreased cell size, with Scer\GAL4MJ94 sNPFdsRNA.Scer\UAS feeding behavior defective | adult stage, with Scer\GAL4MJ94 sNPFdsRNA.Scer\UAS sNPFScer\UAS.cLa feeding behavior defective | larval stage, with Scer\GAL4hs.PB sNPFdsRNA.Scer\UAS sNPFScer\UAS.cLa increased cell size, with Scer\GAL4MJ94 sNPFScer\UAS.cLa large body, with Scer\GAL4MJ94 sNPFScer\UAS.cLa large body, with Scer\GAL4sNPF.2.4 sNPF1.Scer\UAS sNPF2.Scer\UAS sNPFScer\UAS.cLa large body | adult stage, with Scer\GAL4MJ94 sNPFScer\UAS.cLa locomotor behavior defective | adult stage | female, with Scer\GAL4c584 sNPFdsRNA.Scer\UAS locomotor behavior defective | adult stage | male, with Scer\GAL4c584 sNPFdsRNA.Scer\UAS long lived, with Scer\GAL4MJ94 sNPFdsRNA.Scer\UAS small body sNPFc00448 small body, with Scer\GAL4sNPF.2.4 sNPFdsRNA.Scer\UAS Phenotype manifest in Allele embryonic/larval fat body sNPFc00448 embryonic/larval fat body, with Scer\GAL4MJ94 sNPFScer\UAS.cLa sNPFdsRNA.Scer\UAS
Classical Alleles ( 7 )
For All Classical Alleles Show
Allele of sNPF Class Mutagen Stocks Known lesion sNPFc00448 piggyBac transposase 1 -- sNPFc07042 piggyBac transposase 1 -- sNPFf06841 piggyBac transposase 1 -- sNPFf06876 piggyBac transposase 1 -- sNPFf07577 piggyBac transposase 1 -- sNPFMI01807 1 -- sNPFc06659 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sNPF Class Mutagen Stocks Known lesion sNPFJF01906 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sNPF1.Scer\UAS in vitro construct - regulatory fusion 0 Yes sNPF2.Scer\UAS in vitro construct - regulatory fusion 0 Yes sNPFdsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes sNPFGD5419 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes sNPFScer\UAS.cLa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7077 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5419} NA P{TRiP.JF01906} NA P{UAS-sNPF1} NA P{UAS-sNPF2} NA P{UAS-sNPF.L} NA P{UAS-sNPF.RNAi} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}sNPFMI01807 NA PBac{PB}sNPFc00448 NA PBac{PB}sNPFc06659 NA PBac{PB}sNPFc07042 NA PBac{WH}sNPFf06841 NA PBac{WH}sNPFf06876 NA PBac{WH}sNPFf07577 NA
Gene Ontology: Function, Process & Cellular Component ( 15 unique terms )
Terms Based on Experimental Evidence ( 12 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
adult feeding behavior inferred from mutant phenotype (Lee et al., 2004) determination of adult lifespan inferred from mutant phenotype (Lee et al., 2008) larval feeding behavior inferred from mutant phenotype (Lee et al., 2004) multicellular organism growth inferred from mutant phenotype (Lee et al., 2004) positive regulation of cell size inferred from mutant phenotype (Lee et al., 2008) positive regulation of ERK1 and ERK2 cascade inferred from mutant phenotype (Lee et al., 2008) positive regulation of insulin receptor signaling pathway inferred from mutant phenotype (Lee et al., 2008) positive regulation of multicellular organism growth inferred from mutant phenotype (Lee et al., 2004, Lee et al., 2008) regulation of glucose metabolic process inferred from mutant phenotype (Lee et al., 2008) regulation of trehalose metabolic process inferred from mutant phenotype (Lee et al., 2008)
Cellular Component
CV term Evidence References
axon inferred from direct assay (Lee et al., 2009) neuronal cell body inferred from direct assay (Lee et al., 2009)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
hormone activity non-traceable author statement (Hewes and Taghert, 2001) neuropeptide hormone activity inferred from sequence or structural similarity (vanden Broeck, 2001) non-traceable author statement (assigned by UniProtKB) (Baggerman et al., 2002)
Biological Process
CV term Evidence References
neuropeptide signaling pathway inferred from sequence or structural similarity (vanden Broeck, 2001) non-traceable author statement (assigned by UniProtKB) (Baggerman et al., 2002)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sNPF allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0032840
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14444 Dere\GG21216 Dgri\GH13655 Dmoj\GI13671 Dper\GL26344 Dpse\GA12665 Dsec\GM17386 Dsim\GD24240 Dvir\GJ18339 Dwil\GK18728 Dyak\GE13291
Curated drosophilid orthologs	Dpse\GA12665
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012542-PA Aedes aegypti (mosquito) CPIJ009049 Culex pipens (mosquito) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16684 LH17101 LH19624 ISCW007409 FBgn0230977 FBgn0220726 FBgn0205498 FBgn0195588 FBgn0172296 JGI_V11_299864 FBgn0072711 FBgn0163926 FBgn0136426 FBgn0121131 FBgn0113396 FBgn0091471 CPIJ009049 ACYPI49552 GB19695 GB18048 SNPF_AEDAE TC030021
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	25867 y1 v1; P{TRiP.JF01906}attP2 33144 y1 w*; Mi{MIC}sNPFMI01807
Harvard	- PBac{PB}sNPFc00448 - PBac{PB}sNPFc07042 - PBac{WH}sNPFf06841 - PBac{WH}sNPFf06876 - PBac{WH}sNPFf07577
Genomic Clones ( 2 )
	BACR10H13 BACR22E16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 61 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH17539
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RH17691 RH64538
Other clones	15231 29997 35648 42389 45979 64497 64805 97133 158682 159405 163188 CK01.26A.D8 CK01.29D.H3 CK01.60C.F8 CK01.74C.E12 CK01.78D.C6 CK01.78D.E9 CK01.80D.B8 CK01.86C.F2 CK01.88A.A6 CK01.93B.F11 CK01.94A.D2 CK01.97C.D2 CK01.99A.A4 CK01.104D.F3 CK01.105D.F9 CK01.114C.B2 CK01.126C.C9 EK002609 EK024934 EK026223 EK048856 EK058650 EK061233 EK061314 EK062540 EK063656 EK068353 EK069435 EK073245 EK073517 EK075545 EK080721 EK087722 EK088323 EK096911 EK105414 EK138209 EK141402 EK145917 EK157328 EK164438 EK192859 EK192910 EK219656 EK261855 EK262346 EK267364
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032840 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35286
Antibody Information
	polyclonal (Johard et al., 2009, Lee et al., 2004, Lee et al., 2009, Johard et al., 2008, Nässel et al., 2008)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: LRLRFamide CG13968 (Hewes and Taghert, 2001)
Source for database merge of
Additional comments
Other Comments
	sNPF encodes a putative precursor of four "short NPF"-like peptides. (vanden Broeck, 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165316 RefSeq (Proteins) • NP_724239 DDBJ / EMBL / GenBank • AAF53865 AAN11060 AAN71535 AAU87571 AC004364 AY626808 BI611342 BT001780 CZ466466 CZ470899 CZ470900 CZ471192 CZ489570 CZ489611 CZ490325 Entrez Gene - A searchable database of RefSeq genes. • 35286 UniProtKB/Swiss-Prot • Q9VIQ0
Other Crossreferences
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0032840 DRSC - Results from RNAi screens. • FBgn0032840 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032840 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13968-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032840 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35286 InParanoid A subset of ortholog calls from InParanoid. • AAEL012542-PA Aedes aegypti (mosquito) CPIJ009049 Culex pipens (mosquito) modMine - Data generated by the modENCODE project. • FBgn0032840 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16684 LH17101 LH19624 ISCW007409 FBgn0230977 FBgn0220726 FBgn0205498 FBgn0195588 FBgn0172296 JGI_V11_299864 FBgn0072711 FBgn0163926 FBgn0136426 FBgn0121131 FBgn0113396 FBgn0091471 CPIJ009049 ACYPI49552 GB19695 GB18048 SNPF_AEDAE TC030021
Synonyms & Secondary IDs ( 30 )
Reported As
Symbol Synonym	38B.2 (McGill Drosophila Genome Project, 2001.9.25, Butler, 2001, Butler et al., 2001) CG13968 (Butler, 2001, Butler et al., 2001, Hewes and Taghert, 2001, De Loof et al., 2001, Predel et al., 2004, Perkins et al., 1.15.2009, Yew et al., 2009, Wegener and Gorbashov, 2008, Ida et al., 2011, Aerts et al., 2010) Drm-sNPF (Baggerman et al., 2002, vanden Broeck, 2001) Drm-sNPF-1 (Meeusen et al., 2002, Mertens et al., 2002, vanden Broeck, 2001) Drm-sNPF-2 (Mertens et al., 2002, vanden Broeck, 2001) Drm-sNPF-3 (Mertens et al., 2002, vanden Broeck, 2001) Drm-sNPF-4 (Mertens et al., 2002, vanden Broeck, 2001) Drm-sNPF-AP1 (Baggerman et al., 2002) lrlrfa (Melcher and Pankratz, 2005) LRLRFamide (Hewes and Taghert, 2001, ) sNPF (Predel et al., 2004, Yu et al., 2008, Lee et al., 2008, Yew et al., 2009, Lee et al., 2009, Johard et al., 2009, Wegener and Gorbashov, 2008, Wegener et al., 2011, Veenstra et al., 2008, Kahsai et al., 2010, Kula-Eversole et al., 2010, Ida et al., 2011, Nässel et al., 2008, Kahsai et al., 2010, Aerts et al., 2010, Kahsai and Winther, 2011, Damulewicz and Pyza, 2011, Carlsson et al., 2010) snpf (Yu et al., 2004.5.16, Johard et al., 2008, Nässel et al., 2008) s-NPF (Park et al., 2008) sNPF-1 (Feng et al., 2003, Carlsson et al., 2010) sNPF1 (Cazzamali and Grimmelikhuijzen, 2002, Veenstra, 2009) sNPF-2 (Feng et al., 2003, Carlsson et al., 2010) sNPF-2s (Feng et al., 2003) sNPF-3 (Feng et al., 2003, Carlsson et al., 2010) sNPF3 (Veenstra, 2009) sNPF-4 (Feng et al., 2003, Carlsson et al., 2010)
Name Synonym	precursor of short neuropeptide F (Nässel et al., 2008) short neuropeptide F (Yu et al., 2008, Park et al., 2008, Lee et al., 2008, Veenstra, 2009, Lee et al., 2009, Johard et al., 2009, Kahsai et al., 2010, Kahsai and Winther, 2011) Short neuropeptide F (Yew et al., 2009, Johard et al., 2008) short neuropeptide F-1 (Egerod et al., 2003, Egerod et al., 2003, Rosenkilde et al., 2003) short neuropeptide F1 (Jorgensen et al., 2006) short neuropeptide F precursor (vanden Broeck, 2001, Dalton et al., 2010) Short NPF (Predel et al., 2004) short NPF (Ida et al., 2011) small neuropeptide-F (Veenstra et al., 2008) small neuropeptide F-1 (Iversen et al., 2002, Iversen et al., 2002)
Secondary FlyBase IDs
References ( 57 )
Generate a list of	All references relating to this gene ( 57 )
List References by type	Research paper  ( 38 ) Supplementary material  ( 3 ) Review  ( 2 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 4 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 )
Recent research papers ( 11 )
	Damulewicz and Pyza, 2011, PLoS ONE 6(6): e21258 The Clock Input to the First Optic Neuropil of Drosophila melanogaster Expressing Neuronal Circadian Plasticity. [FBrf0214354] Ida et al., 2011, Biochem. Biophys. Res. Commun. 410(4): 872--877 Identification of the novel bioactive peptides dRYamide-1 and dRYamide-2, ligands for a neuropeptide Y-like receptor in Drosophila. [FBrf0214369] Kahsai and Winther, 2011, J. Comp. Neurol. 519(2): 290--315 Chemical neuroanatomy of the Drosophila central complex: distribution of multiple neuropeptides in relation to neurotransmitters. [FBrf0212649] Root et al., 2011, Cell 145(1): 133--144 Presynaptic facilitation by neuropeptide signaling mediates odor-driven food search. [FBrf0213351] Wegener et al., 2011, J. Neurochem. 118(4): 581--595 Deficiency of prohormone convertase dPC2 (AMONTILLADO) results in impaired production of bioactive neuropeptide hormones in Drosophila. [FBrf0214320] Aerts et al., 2010, PLoS Biol. 8(7): e1000435 Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification. [FBrf0211419] Carlsson et al., 2010, J. Comp. Neurol. 518(16): 3359--3380 Multiple neuropeptides in the Drosophila antennal lobe suggest complex modulatory circuits. [FBrf0211156] Dalton et al., 2010, BMC Genomics 11: 541 Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster. [FBrf0212122] Kahsai et al., 2010, PLoS ONE 5(7): e11480 Metabolic stress responses in Drosophila are modulated by brain neurosecretory cells that produce multiple neuropeptides. [FBrf0211291] Kahsai et al., 2010, J. Exp. Biol. 213(13): 2256--2265 Neuropeptides in the Drosophila central complex in modulation of locomotor behavior. [FBrf0211022] Kula-Eversole et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(30): 13497--13502 Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila. [FBrf0211416] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...