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Gene Dmel\CG10949

General Information
Symbol	Dmel\CG10949	Species	D. melanogaster
Name		Annotation symbol	CG10949
Feature type	protein_coding_gene	FlyBase ID	FBgn0032858
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	38C.46
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	38C6-38C6	Sequence location	2L:20,415,171..20,416,918 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10949 (FBgn0032858). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: AT hook, DNA-binding motif; MADF domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1632643_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10949. Gene sequence location is 2L:20415171..20416918.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA02112 BKN24559
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 38C6-38C6   Limits computationally determined from genome sequence between P{EP}CG16798EP401&P{lacW}k07219 and P{lacW}k02501&P{lacW}k14810
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10949 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10949-RA FBtr0081367  NM_136188   1691   459
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10949-PA   FBpp0080899   53.2   459   5.11     NP_610032   AAF53891
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578) AT hook, DNA-binding motif (IPR017956)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA699158   AE014134 AAF53891   AC006402   AI402729   AY058441 AAL13670   BF504410   EV596298   GH943607   GH944397   GH944695   GH946496   GH946502   GH948225   GH948374   GH949805   GH949956   GH952490   GH954266   GH954769   GH954868   GH955293   GH955393   GH955536   GH955837   GH956504   GH956916   GH957061   GH957188   GH957770   GH957869   GH958901   GH959344   GH960006   GH962602   GH963949   GH964995   GH965467   GH965634   GH967488   GH968824   GH969451   GH970687   GH972005   GH974130   GH975559   GH975882   GH978081   GH978387   GH978653   GH979088   GH980668   GH980956   GH984592   GH984603
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VIM6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032858    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032858 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032858 expression level Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1450) embryo 02-04hr  (772) embryo 04-06hr  (1035) embryo 06-08hr  (978) embryo 08-10hr  (844) embryo 10-12hr  (723) embryo 12-14hr  (334) embryo 14-16hr  (214) embryo 16-18hr  (178) embryo 18-20hr  (184) embryo 20-22hr  (171) embryo 22-24hr  (177) larva L1  (272) larva L2  (259) larva L3 12hr old  (200) larva L3 puffstage 1-2  (293) larva L3 puffstage 3-6  (361) larva L3 puffstage 7-9  (438) white prepupae new  (468) white prepupae 12hr  (447) white prepupae 24hr  (571) pupae 2d postWPP  (379) pupae 3d postWPP  (254) pupae 4d postWPP  (194) adult male 01day  (254) adult male 05day  (310) adult male 30day  (319) adult female 01day  (463) adult female 05day  (913) adult female 30day  (896) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032858 expression level Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1450) embryo 02-04hr  (772) embryo 04-06hr  (1035) embryo 06-08hr  (978) embryo 08-10hr  (844) embryo 10-12hr  (723) embryo 12-14hr  (334) embryo 14-16hr  (214) embryo 16-18hr  (178) embryo 18-20hr  (184) embryo 20-22hr  (171) embryo 22-24hr  (177) larva L1  (272) larva L2  (259) larva L3 12hr old  (200) larva L3 puffstage 1-2  (293) larva L3 puffstage 3-6  (361) larva L3 puffstage 7-9  (438) white prepupae new  (468) white prepupae 12hr  (447) white prepupae 24hr  (571) pupae 2d postWPP  (379) pupae 3d postWPP  (254) pupae 4d postWPP  (194) adult male 01day  (254) adult male 05day  (310) adult male 30day  (319) adult female 01day  (463) adult female 05day  (913) adult female 30day  (896) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1450 embryo 02-04hr    772 embryo 04-06hr    1035 embryo 06-08hr    978 embryo 08-10hr    844 embryo 10-12hr    723 embryo 12-14hr    334 embryo 14-16hr    214 embryo 16-18hr    178 embryo 18-20hr    184 embryo 20-22hr    171 embryo 22-24hr    177 larva L1    272 larva L2    259 larva L3 12hr old    200 larva L3 puffstage 1-2    293 larva L3 puffstage 3-6    361 larva L3 puffstage 7-9    438 white prepupae new    468 white prepupae 12hr    447 white prepupae 24hr    571 pupae 2d postWPP    379 pupae 3d postWPP    254 pupae 4d postWPP    194 adult male 01day    254 adult male 05day    310 adult male 30day    319 adult female 01day    463 adult female 05day    913 adult female 30day    896 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032858    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032858 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032858 expression level Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032858 expression level Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    58.475 Larval Midgut    35.7 Larval Hindgut    29.4 Larval Malpighian Tubules    57.2 Larval Fat Body no informative data Larval Salivary Gland    36 Larval Trachea    40.35 Larval Carcass no informative data Adult Head    32 Adult Eye    39.25 Adult Brain    92.4 Adult Thoracic-Abdominal Ganglion    94.8 Adult Crop    42.6 Adult Midgut    46.5 Adult Hindgut    33.7 Adult Malpighian Tubules    50.3 Adult Fat Body no informative data Adult Salivary Gland    52.6 Adult Heart    17.525 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    36 Adult Ovary    103.3 Adult Testis    26 Adult Male Accessory Gland    26.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    32   NA  Eye    39.25   NA  Brain    92.4   58.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    94.8   NA  Crop    42.6   35.7  Midgut    46.5   29.4  Hindgut    33.7   57.2  Malpighian Tubules    50.3   no informative data  Fat Body    no informative data   36  Salivary Gland    52.6   NA  Heart    17.525   40.35  Trachea    NA   NA  VirginFemale Spermatheca    33.2   NA  InseminatedFemale Spermatheca    36   NA  Ovary    103.3   NA  Testis    26   NA  Male Accessory Gland    26.4   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032858 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10949-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG10949GD7140 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG10949 Class Mutagen Stocks Known lesion CG10949e04271 1 -- CG10949EY21171 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10949 Class Mutagen Stocks Known lesion CG10949GD7140 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10949JF02129 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10949KK105423 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6046 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7140} NA P{KK105423} NA P{TRiP.JF02129} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG10949e04271 NA insertion of enhancer trap P{lacW}l(2)SH0251SH0251 No insertion of mobile activating element P{EPgy2}CG10949EY21171 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR017956 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10949 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61276 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0032858 DroID - A comprehensive database of gene and protein interactions. • FBgn0032858 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35310
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15373 Dere\GG21572 Dgri\GH11654 Dmoj\GI17956 Dper\GL26413 Dpse\GA10661 Dsec\GM23328 Dsim\GD21703 Dvir\GJ17728 Dwil\GK18122 Dyak\GE12593
Curated drosophilid orthologs	Dpse\GA10661
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010261-PA Aedes aegypti (mosquito) RP49001 Caenorhabditis remanei (nematode) XP_001180103.1 Strongylocentrotus purpuratus (purple sea urchin) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • ISCW017946 FBgn0230324 FBgn0220121 FBgn0204897 FBgn0193126 FBgn0178195 FBgn0070717 FBgn0163995 FBgn0140696 FBgn0119134 FBgn0113750 FBgn0092398 BGIBMGA009481 ACYPI49244 AAEL015471 AAEL008026 AAEL001555 GLEAN_09795
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	26231 y1 v1; P{TRiP.JF02129}attP2 22455 y1 w67c23; P{EPgy2}CG10949EY21171
Harvard	- PBac{RB}CG10949e04271
VDRC	v107251 P{KK105423}VIE-260B v38426 w1118; P{GD7140}v38426 v38425 w1118; P{GD7140}v38425/TM3
Genomic Clones ( 2 )
	BACR03G24 BACR08D17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 52 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH22016
Other clones	DPiM_GH22016
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05764 HL07819
Other clones	Dmel_neb_016319_0952_1782 RP004002368 RP004019642 RP004048824 RP004051217 RP004063866 RP004066763 RP004069159 RP004077509 RP004090376 RP004094273 RP004098761 RP004100471 RP004106576 RP004109022 RP004116941 RP004143645 RP004178801 RP004181414 RP004196258 RP004196571 RP004196928 RP004199007 RP004219257 RP004219667 RP004235974 RP004238047 RP004238310 RP004241133 RP004248941 RP004254781 RP004258479 RP004260382 RP004264229 RP004332661 RP004339325 RP004370089 RP004404130 RP004423433 RP004441563 RP004449998 RP004466672 RP004489226 RP004491478 RP004496913 RP004509566 RP004524137 RP004550202
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032858 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35310
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136188 RefSeq (Proteins) • NP_610032 DDBJ / EMBL / GenBank • AAF53891 AAL13670 AC006402 AI402729 AY058441 Entrez Gene - A searchable database of RefSeq genes. • 35310 UniProtKB/TrEMBL • Q9VIM6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578) AT hook, DNA-binding motif (IPR017956)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61276 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0032858 DroID - A comprehensive database of gene and protein interactions. • FBgn0032858 DRSC - Results from RNAi screens. • FBgn0032858 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032858 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10949-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032858 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35310 InParanoid A subset of ortholog calls from InParanoid. • AAEL010261-PA Aedes aegypti (mosquito) RP49001 Caenorhabditis remanei (nematode) XP_001180103.1 Strongylocentrotus purpuratus (purple sea urchin) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35310 modMine - Data generated by the modENCODE project. • FBgn0032858 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • ISCW017946 FBgn0230324 FBgn0220121 FBgn0204897 FBgn0193126 FBgn0178195 FBgn0070717 FBgn0163995 FBgn0140696 FBgn0119134 FBgn0113750 FBgn0092398 BGIBMGA009481 ACYPI49244 AAEL015471 AAEL008026 AAEL001555 GLEAN_09795
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	38C.46 (McGill Drosophila Genome Project, 2001.9.25, Butler, 2001, Butler et al., 2001) CG10949 (Perkins et al., 2009.3.31, Keleman et al., 2009.8.5) FBgn0032858 (Raychaudhuri et al., 2003)
Name Synonym
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 4 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 2 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...