Arc-p34, 38C.47, p34
Gene model reviewed during 5.55
Gene model reviewed during 5.44
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
Gene model reviewed during 5.56
Component of the Arp2/3 complex.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Arpc2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Arpc2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Arc-p34 anon-WO0118547.154
FlyBase Curator comment: 'Arc-p34' renamed to 'Arpc2' to rationalize the nomenclature of genes encoding subunits of the Actin-related protein 2/3 complex, following the nomenclature suggested in FBrf0144947 which is consistent with that used in mammals.
Source for merge of Arc-p34 anon-WO0118547.154 was sequence comparison ( date:051113 ).
S2 cells treated with dsRNA directed against Arc-p34 produce prominent filopodia and fail to internalize bound bacteria in a phagocytosis assay.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become retracted (unspread but flat). Kc167 cells are unaffected.
The Arp2/3 complex (including Arc-p34) is required for actin cap expansion and pseudocleavage furrow formation during syncytial blastoderm divisions.
Area matching Drosophila EST AA951902 (inverted). This EST matches other EST including AA949796.