Gene Dmel\CG9257

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General Information

Symbol

Dmel\CG9257

Species

D. melanogaster

Name

Annotation symbol

CG9257

Feature type

protein_coding_gene

FlyBase ID

FBgn0032916

Gene Model Status

Current

Stock availability

5 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

39A2-39A2

Sequence location

2L:21,102,743..21,104,321 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG9257 (FBgn0032916). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Malectin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval hindgut, larval fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1624665_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9257. Gene sequence location is 2L:21102743..21104321.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

39A2-39A2

Limits computationally determined from genome sequence between P{PZ}l(2)05287⁰⁵²⁸⁷ and P{lacW}l(2)k07215^k07215&P{lacW}snRNA:U4:39B^k09410

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG9257 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG9257-RA

FBtr0081465

NM_136243

1579

347

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG9257-PA

FBpp0080994

39.3

347

4.90

NP_610087

AAF53959

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Malectin (IPR021720)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval hindgut, larval fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		(697.1)
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		192.4
Larval Midgut		158.4
Larval Hindgut		148.1
Larval Malpighian Tubules		45.6
Larval Fat Body		151.7
Larval Salivary Gland		697.1
Larval Trachea		162.075
Larval Carcass		226.25
Adult Head		126.6
Adult Eye		156.7
Adult Brain		298.1
Adult Thoracic-Abdominal Ganglion		495.1
Adult Crop		67
Adult Midgut		112
Adult Hindgut		56.9
Adult Malpighian Tubules		46.2
Adult Fat Body		96.7
Adult Salivary Gland		187.2
Adult Heart		60.175
Adult VirginFemale Spermatheca		144.7
Adult InseminatedFemale Spermatheca		159.3
Adult Ovary		282.9
Adult Testis		75.3
Adult Male Accessory Gland		323.1
Adult Carcass		93.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	126.6
NA	Eye	156.7
NA	Brain	298.1
192.4	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	495.1
NA	Crop	67
158.4	Midgut	112
148.1	Hindgut	56.9
45.6	Malpighian Tubules	46.2
151.7	Fat Body	96.7
697.1	Salivary Gland	187.2
NA	Heart	60.175
162.075	Trachea	NA
NA	VirginFemale Spermatheca	144.7
NA	InseminatedFemale Spermatheca	159.3
NA	Ovary	282.9
NA	Testis	75.3
NA	Male Accessory Gland	323.1
226.25	Carcass	93.4

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		(44)
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		(47)
ovary, mated 4-day female		(43)
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		(44)
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		(47)
ovary, mated 4-day female		(43)
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		21
central nervous system, larvae L3		15
central nervous system, pupae P8		44
head, virgin 1-day female		13
head, virgin 4-day female		13
head, virgin 20-day female		10
head, mated 1-day female		15
head, mated 4-day female		16
head, mated 20-day female		8
head, mated 1-day male		16
head, mated 4-day male		21
head, mated 20-day male		16
salivary gland, larvae L3 wandering		8
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		7
fat body, white prepupae		9
fat body, pupae P8		22
carcass, larvae L3 wandering		18
carcass, 1-day adult		7
carcass, 4-day adult		11
carcass, 20-day adult		7
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		23
accessory gland, mated 4-day male		14
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		21
embryo 02-04hr		5
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		6
embryo 14-16hr		3
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		3
embryo 22-24hr		3
larva L1		6
larva L2		7
larva L3 12hr old		7
larva L3 puffstage 1-2		5
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		10
white prepupae new		9
white prepupae 12hr		7
white prepupae 24hr		9
pupae 2d postWPP		12
pupae 3d postWPP		7
pupae 4d postWPP		3
adult male 01day		5
adult male 05day		6
adult male 30day		6
adult female 01day		8
adult female 05day		17
adult female 30day		18
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(27)
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		(28)
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		(30)
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		(28)
CNS ML-DmBG2-c2		(42)
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		(42)
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		27
Schneider line 2 Sg4		22
embryonic 1182-4H		17
embryonic GM2		26
embryonic Kc167		15
embryonic S1		20
embryonic S3		11
leg disc CME L1		26
wing disc CME-W2		18
wing disc ML-DmD8		11
wing disc ML-DmD9		22
wing disc ML-DmD16-c3		21
wing disc ML-DmD21		28
wing disc ML-DmD32		14
haltere disc ML-DmD17-c3		18
eye-antennal disc ML-DmD11		30
antennal disc ML-DmD20-c5		24
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		28
CNS ML-DmBG2-c2		42
tumorous blood cells mbn2		17
ovary fGS/OSS		22
ovary OSC		23
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		(27)
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		16
cold shock, 4-day adult		11
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		13
Cadmium 50 mM 12 hrs, larvae L3		12
Cadmium 50 mM 48 hrs, 4-day adult		18
Cadmium 100 mM 48 hrs, 4-day adult		26
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		13
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		27
Ethanol 5% 3 hrs, larvae L3		8
Ethanol 10% 3 hrs, larvae L3		12
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		19
Paraquat 5 mM 48 hrs, 4-day adult		21
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		13
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0032916

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG9257-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG9257^GD1795

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG9257	Class	Mutagen	Stocks	Known lesion
CG9257^d00169		P-element activity	1	--
CG9257^KG06051			1	--

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG9257	Mutagen	Stocks	Known lesion
CG9257^GD1795	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9257^HMS02123	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9257^KK100869	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG9257^NIG.9556R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel6047

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{XP}CG9257^d00169

miscellaneous insertions

P{SUPor-P}CG9257^KG06051

P{SUPor-P}Nhe2^KG06975

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG9257 - CG11911

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Mintseris et al., 2009.11.23, Guruharsha et al., 2011)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG9257 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

61331

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0032916

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

35375

Orthologs

OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG68PN58

Dipteran inclusive ortholog search

EOG69GKRF

Insect inclusive ortholog search

EOG6MPGKW

Arthropod inclusive ortholog search

EOG6VT4CZ

Metazoa inclusive ortholog search

EOG6H1PPK

Orthologs in Drosophila Species (EOG68PN58)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21649

Drosophila persimilis

Dper\GL25887

Drosophila willistoni

Dwil\GK24317

Drosophila virilis

Dvir\GJ23801

Drosophila mojavensis

Dmoj\GI23293

Drosophila grimshawi

Dgri\GH10409

Orthologs in non-Drosophila Dipterans (EOG69GKRF)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005016

Anopheles gambiae

Malaria mosquito

Agam\AGAP007950

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ001505

Orthologs in non-Dipteran Insects (EOG6MPGKW)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB40712

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG002831

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH10162

Atta cephalotes

Leafcutter ant

Acep\ACEP20724

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO18003

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL16108

Linepithema humile

Argentine ant

Lhum\LH12363

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB15586

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002193

Bombyx mori

Silkmoth

Bmor\BGIBMGA006789

Pediculus humanus

Human body louse

Phum\PHUM320110

Tribolium castaneum

Red flour beetle

Tcas\TC011968

Orthologs in non-Insect Arthropods (EOG6VT4CZ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Ciapin1

Ixodes scapularis

Deer tick

Isca\ISCW024140

Ixodes scapularis

Deer tick

Isca\ISCW011374

Orthologs in non-Arthropod Metazoa (EOG6H1PPK)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\F44E2.10

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_006160gn

Danio rerio

Zebrafish

Drer\mlec

Xenopus tropicalis

Western clawed frog

Xtro\mlec

Gallus gallus

Domestic chicken

Ggal\MLEC

Mus musculus

House mouse

Mmus\Mlec

Rattus norvegicus

Norway rat

Rnor\Mlec

Homo sapiens

Human

Hsap\MLEC

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\MLEC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21649

Drosophila persimilis

Dper\GL25887

Drosophila willistoni

Dwil\GK24317

Drosophila virilis

Dvir\GJ23801

Drosophila mojavensis

Dmoj\GI23293

Drosophila grimshawi

Dgri\GH10409

Stocks & Reagents

Stocks Listed in FlyBase ( 5 )

Bloomington

42582

y¹ v¹; P{TRiP.HMS02123}attP40

14471

y¹ w^67c23; P{SUPor-P}CG9257^KG06051

v103425

v6406

w¹¹¹⁸; P{GD1795}v6406

Genomic Clones ( 1 )

BACR24F17

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 10 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones