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Gene Dmel\CG9253

General Information
Symbol	Dmel\CG9253	Species	D. melanogaster
Name		Annotation symbol	CG9253
Feature type	protein_coding_gene	FlyBase ID	FBgn0032919
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	39A4-39A4	Sequence location	2L:21,143,227..21,145,147 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9253 (FBgn0032919). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640080_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG9253. Gene sequence location is 2L:21143227..21145147.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN20601 HFA03171
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 39A4-39A4   Limits computationally determined from genome sequence between P{PZ}l(2)0528705287 and P{lacW}l(2)k07215k07215&P{lacW}snRNA:U4:39Bk09410
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9253 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9253-RA FBtr0081468  NM_136246   1672   507
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9253-PA   FBpp0080997   56.5   507   6.80     NP_610090   AAF53963
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) DEAD-like helicase (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264415   AA536567   AA540284   AA695820   AA802607   AA949063   AA949073   AA950858   AE014134 AAF53963   AI532059   AY121677 AAM52004   BF492010   BG641340   BH809474   BI167777   BI173927   BI214042   BI215892   BI227628   BI229701   BI230968   BI232627   BI362641   BI362654   BI364834   BI580730   BI620452   BI638259   BI638459   BI638820   BI641414   BP557502   BP558713   CK660341   CL610122   CO153873   EC078601   EC255635   EC259052   EV578161   EV584645   EV585209   X65273
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MRB7 Q9VIF6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0032919    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0032919 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0032919 expression level Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr    11561 embryo 08-10hr    10812 embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4932) embryo 02-04hr  (8109) embryo 04-06hr  (9567) embryo 06-08hr  (11561) embryo 08-10hr  (10812) embryo 10-12hr  (6955) embryo 12-14hr  (6483) embryo 14-16hr  (3629) embryo 16-18hr  (3237) embryo 18-20hr  (2920) embryo 20-22hr  (7734) embryo 22-24hr  (7462) larva L1  (9530) larva L2  (4668) larva L3 12hr old  (3059) larva L3 puffstage 1-2  (1585) larva L3 puffstage 3-6  (1780) larva L3 puffstage 7-9  (2146) white prepupae new  (1858) white prepupae 12hr  (2125) white prepupae 24hr  (2146) pupae 2d postWPP  (1740) pupae 3d postWPP  (1089) pupae 4d postWPP  (1109) adult male 01day  (938) adult male 05day  (943) adult male 30day  (948) adult female 01day  (4400) adult female 05day  (6510) adult female 30day  (5980) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4932) embryo 02-04hr  (8109) embryo 04-06hr  (9567) embryo 06-08hr  (11561) embryo 08-10hr  (10812) embryo 10-12hr  (6955) embryo 12-14hr  (6483) embryo 14-16hr  (3629) embryo 16-18hr  (3237) embryo 18-20hr  (2920) embryo 20-22hr  (7734) embryo 22-24hr  (7462) larva L1  (9530) larva L2  (4668) larva L3 12hr old  (3059) larva L3 puffstage 1-2  (1585) larva L3 puffstage 3-6  (1780) larva L3 puffstage 7-9  (2146) white prepupae new  (1858) white prepupae 12hr  (2125) white prepupae 24hr  (2146) pupae 2d postWPP  (1740) pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day  (4400) adult female 05day  (6510) adult female 30day  (5980) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr  (11561) embryo 08-10hr  (10812) embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr    11561 embryo 08-10hr    10812 embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0032919 expression level Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr    11561 embryo 08-10hr    10812 embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4932) embryo 02-04hr  (8109) embryo 04-06hr  (9567) embryo 06-08hr  (11561) embryo 08-10hr  (10812) embryo 10-12hr  (6955) embryo 12-14hr  (6483) embryo 14-16hr  (3629) embryo 16-18hr  (3237) embryo 18-20hr  (2920) embryo 20-22hr  (7734) embryo 22-24hr  (7462) larva L1  (9530) larva L2  (4668) larva L3 12hr old  (3059) larva L3 puffstage 1-2  (1585) larva L3 puffstage 3-6  (1780) larva L3 puffstage 7-9  (2146) white prepupae new  (1858) white prepupae 12hr  (2125) white prepupae 24hr  (2146) pupae 2d postWPP  (1740) pupae 3d postWPP  (1089) pupae 4d postWPP  (1109) adult male 01day  (938) adult male 05day  (943) adult male 30day  (948) adult female 01day  (4400) adult female 05day  (6510) adult female 30day  (5980) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4932) embryo 02-04hr  (8109) embryo 04-06hr  (9567) embryo 06-08hr  (11561) embryo 08-10hr  (10812) embryo 10-12hr  (6955) embryo 12-14hr  (6483) embryo 14-16hr  (3629) embryo 16-18hr  (3237) embryo 18-20hr  (2920) embryo 20-22hr  (7734) embryo 22-24hr  (7462) larva L1  (9530) larva L2  (4668) larva L3 12hr old  (3059) larva L3 puffstage 1-2  1585 larva L3 puffstage 3-6  1780 larva L3 puffstage 7-9  2146 white prepupae new  1858 white prepupae 12hr  2125 white prepupae 24hr  2146 pupae 2d postWPP  1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day  (4400) adult female 05day  (6510) adult female 30day  (5980) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr  11561 embryo 08-10hr  10812 embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4932 embryo 02-04hr    8109 embryo 04-06hr    9567 embryo 06-08hr    11561 embryo 08-10hr    10812 embryo 10-12hr    6955 embryo 12-14hr    6483 embryo 14-16hr    3629 embryo 16-18hr    3237 embryo 18-20hr    2920 embryo 20-22hr    7734 embryo 22-24hr    7462 larva L1    9530 larva L2    4668 larva L3 12hr old    3059 larva L3 puffstage 1-2    1585 larva L3 puffstage 3-6    1780 larva L3 puffstage 7-9    2146 white prepupae new    1858 white prepupae 12hr    2125 white prepupae 24hr    2146 pupae 2d postWPP    1740 pupae 3d postWPP    1089 pupae 4d postWPP    1109 adult male 01day    938 adult male 05day    943 adult male 30day    948 adult female 01day    4400 adult female 05day    6510 adult female 30day    5980 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0032919    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0032919 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0032919 expression level Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary  513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0032919 expression level Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary  513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    480.175 Larval Midgut    80.3 Larval Hindgut    177.5 Larval Malpighian Tubules    61.9 Larval Fat Body    68.7 Larval Salivary Gland    217.9 Larval Trachea    457.325 Larval Carcass    253.8 Adult Head    190.9 Adult Eye    188.4 Adult Brain    238.8 Adult Thoracic-Abdominal Ganglion    364.5 Adult Crop    211.9 Adult Midgut    117.9 Adult Hindgut    161.7 Adult Malpighian Tubules    281.4 Adult Fat Body    353.3 Adult Salivary Gland    188.8 Adult Heart    257.25 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    369.3 Adult Ovary    513 Adult Testis    48.2 Adult Male Accessory Gland    310.7 Adult Carcass    219.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    190.9   NA  Eye    188.4   NA  Brain    238.8   480.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    364.5   NA  Crop    211.9   80.3  Midgut    117.9   177.5  Hindgut    161.7   61.9  Malpighian Tubules    281.4   68.7  Fat Body    353.3   217.9  Salivary Gland    188.8   NA  Heart    257.25   457.325  Trachea    NA   NA  VirginFemale Spermatheca    276.2   NA  InseminatedFemale Spermatheca    369.3   NA  Ovary    513   NA  Testis    48.2   NA  Male Accessory Gland    310.7   253.8  Carcass    219.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032919 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9253-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG9253 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG9253GD14168 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG9253 Class Mutagen Stocks Known lesion CG9253EY02880 P-element activity 2 -- CG9253KG05120 P-element activity 1 -- CG9253Δ6 Delta2-3 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9253 Class Mutagen Stocks Known lesion CG9253GD14168 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(2L)10523-17 (Marie et al., 2004)
Disrupted in	Df(2L)Exel6047 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14168} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG9253EY02880 NA insertion of enhancer trap P{lacW}l(2)SH0471SH0471 No miscellaneous insertions P{SUPor-P}CG9253KG05120 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent RNA helicase activity inferred from sequence or structural similarity with Saccharomyces RRP3 (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9253 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61334 DroID - A comprehensive database of gene and protein interactions. • FBgn0032919 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35379
Orthologs
Genome-wide drosophilid orthologs	Dana\GF14739 Dere\GG21281 Dgri\GH13670 Dmoj\GI21075 Dper\GL25891 Dpse\GA21647 Dsec\GM23393 Dsim\GD24302 Dvir\GJ16136 Dwil\GK21047 Dyak\GE12898
Curated drosophilid orthologs	Dpse\GA21647
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013950-PA Aedes aegypti (mosquito) AGAP009808-PA Anopheles gambiae (mosquito) XP_395653.2 Apis mellifera (honey bee) XP_001951837.1 Acyrthosiphon pisum (pea aphid) At5g60990.1 Arabidopsis thaliana (wall cress) 87448 Batrachochytrium dendrobatidis (chytrid fungus) 57422 Branchiostoma floridae (lancelet) XP_001896476.1 Brugia malayi (roundworm nematode) BGIBMGA009885-PA Bombyx mori (silk worm) ENSBTAP00000003058 Bos taurus (bovine) CAL0000056 Candida albicans (a form of yeast) CN02697 Caenorhabditis brenneri (small nematode) CBP02482 Caenorhabditis briggsae (nematode) CE00337 Caenorhabditis elegans (worm) ENSCAFP00000019496 Canis familiaris (dog) CAGL0J10912g Candida glabrata (haploid yeast) Chro.40362 Cryptosporidium hominis (obligate parasite) ENSCINP00000004240 Ciona intestinalis (sea squirt) JA14716 Caenorhabditis japonica (nematode) CMK083C Cyanidioschyzon merolae (red alga) cn08277 Cryptococcus neoformans (yeast-like fungus) cgd4_3180 Cryptosporidium parvum (protozoan parasite) CPIJ008842 Culex pipens (mosquito) ENSCPOP00000001749 Cavia porcellus (guinea pig) 223 Chlamidomonas reinhardtii (green alga) RP29758 Caenorhabditis remanei (nematode) ENSCSAVP00000019725 Ciona savignyi (sedentary tunicate) 175937 Capitella spl (polychaete worm) DDB0234204 Dictyostelium discoideum (amoeba) DEHA2E08052g Debaryomyces Hansenii (yeast) 226459 Daphnia pulex (daphnia) ENSECAP00000021211 Equus caballus (horse) NP_417631.2 Escherichia coli K12 (bacteria) XP_654408 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000009427 Gymnopilus aculeatus (mushroom) ENSGALP00000019220 Gallus gallus (chicken) GL50803_9119 Giardia lamblia (flagellated protozoan) 185175 Hypsipyla robusta (cedar shoot borer) ENSP00000350698 Homo sapiens (human) ISCW020807-PA Ixodes scapularis (deer tick) KLLA0C14608g Kluyveromyces lactis (yeast) 229010 Lottia gigantea (owl limpet) LmjF36.1850 Leishmania major (virus) 37739 Monocosta brevicollis (choanoflagellate) ENSMODP00000022722 Monodelphis domestica (gray opossum) ENSMMUP00000023651 Macaca mulatta (rhesus monkey) ENSMUSP00000032326 Mus musculus (house mouse) 192845 Nematostella vectensis (starlet anemone) XP_001601432.1 Nasonia vitripennis (wasp) ENSOANP00000004795 Ornithorynchus anatinus (platypus) ENSORLP00000018827 Oryzias latipes (japanese killifish) LOC_Os03g46610.1 Oryza sativa (asian rice) 24293 Ostreococcus tauri (green alga) PFB0860c Plasmodium falciparum (protozoal parasite) PHUM006157-PA Pediculus humanus (human body louse) PP18910 Pristionchus pacificus (nematode) 178010 Physcomitrella patens (moss) ENSPPYP00000004923 Pongo pygmaeus (orangutan) 80574 Phytophthora ramorum (sudden oak death pathogen) 108838 Phytophthora sojae (root rot pathogen) 218296 Populus trichocarpa (black cottonwood) ENSPTRP00000058198 Pan troglodytes (chimpanzee) PVX_002620 Plasmodium vivax (protozoal parasite) ENSRNOP00000011096 Rattus norvegicus (norway rat) 5050333 Sorghum bicolor (sorghum) YHR065C Saccharomyces cerevisiae (budding yeast) Smp_090440 Schistosoma mansoni (trematode parasite) SPAC823.08c Schizosaccharomyces pombe (fission yeast) XP_786173.2 Strongylocentrotus purpuratus (purple sea urchin) 21567 Trichoplax adhaerens (metazoa) TA14795 Theileria annulata (apicomplexan parasite) XP_969791.1 Tribolium castaneum (red flour beetle) Tc00.1047053507641.140 Trypanosoma cruzi (parasitic trypanosome) TP02_0728 Theileria parva (parasitic protozoan) 14597 Thalassiosira pseudonana (marine diatom) 7.m00301 Tetrahymena thermophila (ciliate protozoa) 96713.m00134 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000049718 Xenopus tropicalis (frog) YALI0A12133g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15612 NV13752 LH12349 FBgn0230613 FBgn0223039 FBgn0203321 FBgn0195649 FBgn0178260 JGI_V11_226459 FBgn0081632 FBgn0163475 FBgn0143807 FBgn0121146 FBgn0113460 FBgn0091766 CPIJ008842 BGIBMGA009885 ACYPI008489 GB17141 AGAP009808 AAEL013950 PHUM023260 GLEAN_06210
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	19661 y1 w67c23; P{EPgy2}CG9253EY02880/CyO 13988 y1; P{SUPor-P}CG9253KG05120/CyO; ry506
Kyoto	114566 yd2 w1118 P{ey-FLP.N}2; P{EPgy2}CG9253EY02880 P{neoFRT}40A/CyO y+
Genomic Clones ( 1 )
	BACR24F17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 38 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE27528
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT28871 GM04542 GM06001 LD08157 LD17327 LD19730 LD27815 LD27829 LD31009 LP18835 RE08240 RE16642 RE17075 RE19736 RE22656 RE24731 RE28726 RE47257 RE47270 RE50024 RE74954 RH51604 SD03422 SD12661 SD20505 SD20752 SD21211 SD24733
Other clones	177113 214353.13 214385.4 Dmel_dig_004702_0599_1814 Dmel_dig_007828_0610_1707 Dmel_dig_014428_0705_3057 EN03008 FGM309F08 FGM316F07
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0032919 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35379
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG9253 anon-EST:GressD10 (Ashburner, 2004.6.30)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136246 RefSeq (Proteins) • NP_610090 DDBJ / EMBL / GenBank • AAF53963 AAM52004 AY121677 BH809474 BI229701 CL610122 X65273 Entrez Gene - A searchable database of RefSeq genes. • 35379 UniProtKB/TrEMBL • Q8MRB7 Q9VIF6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) DEAD-like helicase (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61334 DroID - A comprehensive database of gene and protein interactions. • FBgn0032919 DRSC - Results from RNAi screens. • FBgn0032919 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0032919 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9253-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0032919 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35379 InParanoid A subset of ortholog calls from InParanoid. • AAEL013950-PA Aedes aegypti (mosquito) AGAP009808-PA Anopheles gambiae (mosquito) XP_395653.2 Apis mellifera (honey bee) XP_001951837.1 Acyrthosiphon pisum (pea aphid) At5g60990.1 Arabidopsis thaliana (wall cress) 87448 Batrachochytrium dendrobatidis (chytrid fungus) 57422 Branchiostoma floridae (lancelet) XP_001896476.1 Brugia malayi (roundworm nematode) BGIBMGA009885-PA Bombyx mori (silk worm) ENSBTAP00000003058 Bos taurus (bovine) CAL0000056 Candida albicans (a form of yeast) CN02697 Caenorhabditis brenneri (small nematode) CBP02482 Caenorhabditis briggsae (nematode) CE00337 Caenorhabditis elegans (worm) ENSCAFP00000019496 Canis familiaris (dog) CAGL0J10912g Candida glabrata (haploid yeast) Chro.40362 Cryptosporidium hominis (obligate parasite) ENSCINP00000004240 Ciona intestinalis (sea squirt) JA14716 Caenorhabditis japonica (nematode) CMK083C Cyanidioschyzon merolae (red alga) cn08277 Cryptococcus neoformans (yeast-like fungus) cgd4_3180 Cryptosporidium parvum (protozoan parasite) CPIJ008842 Culex pipens (mosquito) ENSCPOP00000001749 Cavia porcellus (guinea pig) 223 Chlamidomonas reinhardtii (green alga) RP29758 Caenorhabditis remanei (nematode) ENSCSAVP00000019725 Ciona savignyi (sedentary tunicate) 175937 Capitella spl (polychaete worm) DDB0234204 Dictyostelium discoideum (amoeba) DEHA2E08052g Debaryomyces Hansenii (yeast) 226459 Daphnia pulex (daphnia) ENSECAP00000021211 Equus caballus (horse) NP_417631.2 Escherichia coli K12 (bacteria) XP_654408 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000009427 Gymnopilus aculeatus (mushroom) ENSGALP00000019220 Gallus gallus (chicken) GL50803_9119 Giardia lamblia (flagellated protozoan) 185175 Hypsipyla robusta (cedar shoot borer) ENSP00000350698 Homo sapiens (human) ISCW020807-PA Ixodes scapularis (deer tick) KLLA0C14608g Kluyveromyces lactis (yeast) 229010 Lottia gigantea (owl limpet) LmjF36.1850 Leishmania major (virus) 37739 Monocosta brevicollis (choanoflagellate) ENSMODP00000022722 Monodelphis domestica (gray opossum) ENSMMUP00000023651 Macaca mulatta (rhesus monkey) ENSMUSP00000032326 Mus musculus (house mouse) 192845 Nematostella vectensis (starlet anemone) XP_001601432.1 Nasonia vitripennis (wasp) ENSOANP00000004795 Ornithorynchus anatinus (platypus) ENSORLP00000018827 Oryzias latipes (japanese killifish) LOC_Os03g46610.1 Oryza sativa (asian rice) 24293 Ostreococcus tauri (green alga) PFB0860c Plasmodium falciparum (protozoal parasite) PHUM006157-PA Pediculus humanus (human body louse) PP18910 Pristionchus pacificus (nematode) 178010 Physcomitrella patens (moss) ENSPPYP00000004923 Pongo pygmaeus (orangutan) 80574 Phytophthora ramorum (sudden oak death pathogen) 108838 Phytophthora sojae (root rot pathogen) 218296 Populus trichocarpa (black cottonwood) ENSPTRP00000058198 Pan troglodytes (chimpanzee) PVX_002620 Plasmodium vivax (protozoal parasite) ENSRNOP00000011096 Rattus norvegicus (norway rat) 5050333 Sorghum bicolor (sorghum) YHR065C Saccharomyces cerevisiae (budding yeast) Smp_090440 Schistosoma mansoni (trematode parasite) SPAC823.08c Schizosaccharomyces pombe (fission yeast) XP_786173.2 Strongylocentrotus purpuratus (purple sea urchin) 21567 Trichoplax adhaerens (metazoa) TA14795 Theileria annulata (apicomplexan parasite) XP_969791.1 Tribolium castaneum (red flour beetle) Tc00.1047053507641.140 Trypanosoma cruzi (parasitic trypanosome) TP02_0728 Theileria parva (parasitic protozoan) 14597 Thalassiosira pseudonana (marine diatom) 7.m00301 Tetrahymena thermophila (ciliate protozoa) 96713.m00134 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000049718 Xenopus tropicalis (frog) YALI0A12133g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35379 modMine - Data generated by the modENCODE project. • FBgn0032919 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15612 NV13752 LH12349 FBgn0230613 FBgn0223039 FBgn0203321 FBgn0195649 FBgn0178260 JGI_V11_226459 FBgn0081632 FBgn0163475 FBgn0143807 FBgn0121146 FBgn0113460 FBgn0091766 CPIJ008842 BGIBMGA009885 ACYPI008489 GB17141 AGAP009808 AAEL013950 PHUM023260 GLEAN_06210
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	anon-EST:GressD10   cg9253 (Lasko, 2000) CG9253 (Huang et al., 2005, Telonis-Scott et al., 2009, Casper and Van Doren, 2009) DmRH24 (Boudet et al., 2001)
Name Synonym
Secondary FlyBase IDs
	FBgn0025331
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 10 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 3 ) FlyBase analysis  ( 1 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Show all research papers ...