Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Self-associates. Interacts with Mcm2, dup, Orc2, CDC45L and Su(var)205.
The zinc finger-like domain binds a zinc ion and is involved in self-association.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mcm10 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Mcm10 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Mcm10 CG9241
Source for merge of: Mcm10 Scim19 CG9241
Maternally loaded Mcm10 protein is required for nuclear stability in early embryogenesis. It is also required for the development and/or maintenance of the female germline.
Mcm10 interacts with members of the pre-RC and is required for proper chromosome condensation.
Identification: In a screen for chromosome inheritance modifiers.