Gene Dmel\CG14464

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General Information

Symbol

Dmel\CG14464

Species

D. melanogaster

Name

Annotation symbol

CG14464

Feature type

protein_coding_gene

FlyBase ID

FBgn0033000

Gene Model Status

Current

Stock availability

2 publicly available

Also Known As

CG40285

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

41C3-41C3

Sequence location

2R:716,751..717,440 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG14464 (FBgn0033000). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640762_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG14464. Gene sequence location is 2R:716751..717440.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

41C3-41C3

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

41C1-41C6

h46

(Drosophila Heterochromatin Genome Project, 2004)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG14464 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG14464-RC

FBtr0299923

NM_001043001

637

116

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG14464-PC

FBpp0289201

13.7

116

8.77

NP_001036466

EAA45996

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

eye

(Xu et al., 2004)

Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		1210.3
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1060.175)
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		(952.225)
Larval Carcass		368.1
Adult Head		434
Adult Eye		(897.5)
Adult Brain		(741.2)
Adult Thoracic-Abdominal Ganglion		(868.5)
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		(1210.3)
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		(1210.3)
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		1210.3
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		1210.3
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1060.175)
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		(952.225)
Larval Carcass		368.1
Adult Head		434
Adult Eye		(897.5)
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		(868.5)
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		(1210.3)
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		1210.3
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1060.175
Larval Midgut		302.3
Larval Hindgut		347.5
Larval Malpighian Tubules		346.6
Larval Fat Body		388.1
Larval Salivary Gland		334.9
Larval Trachea		952.225
Larval Carcass		368.1
Adult Head		434
Adult Eye		897.5
Adult Brain		741.2
Adult Thoracic-Abdominal Ganglion		868.5
Adult Crop		330.6
Adult Midgut		223.5
Adult Hindgut		275.7
Adult Malpighian Tubules		161
Adult Fat Body		225.7
Adult Salivary Gland		307.8
Adult Heart		386.75
Adult VirginFemale Spermatheca		324.4
Adult InseminatedFemale Spermatheca		355.6
Adult Ovary		1210.3
Adult Testis		124.5
Adult Male Accessory Gland		274.3
Adult Carcass		189.3
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	434
NA	Eye	897.5
NA	Brain	741.2
1060.175	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	868.5
NA	Crop	330.6
302.3	Midgut	223.5
347.5	Hindgut	275.7
346.6	Malpighian Tubules	161
388.1	Fat Body	225.7
334.9	Salivary Gland	307.8
NA	Heart	386.75
952.225	Trachea	NA
NA	VirginFemale Spermatheca	324.4
NA	InseminatedFemale Spermatheca	355.6
NA	Ovary	1210.3
NA	Testis	124.5
NA	Male Accessory Gland	274.3
368.1	Carcass	189.3

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		(29)
central nervous system, pupae P8		(38)
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		(30)
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		(72)
ovary, mated 4-day female		(56)
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		(38)
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		(72)
ovary, mated 4-day female		(56)
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		14
central nervous system, larvae L3		29
central nervous system, pupae P8		38
head, virgin 1-day female		10
head, virgin 4-day female		11
head, virgin 20-day female		5
head, mated 1-day female		7
head, mated 4-day female		10
head, mated 20-day female		4
head, mated 1-day male		8
head, mated 4-day male		14
head, mated 20-day male		15
salivary gland, larvae L3 wandering		6
salivary gland, white prepupae		4
digestive system, larvae L3 wandering		12
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		6
fat body, larvae L3 wandering		4
fat body, white prepupae		10
fat body, pupae P8		30
carcass, larvae L3 wandering		13
carcass, 1-day adult		6
carcass, 4-day adult		9
carcass, 20-day adult		5
ovary, virgin 4-day female		72
ovary, mated 4-day female		56
testis, mated 4-day male		9
accessory gland, mated 4-day male		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(41)
embryo 02-04hr		(57)
embryo 04-06hr		(42)
embryo 06-08hr		(32)
embryo 08-10hr		(52)
embryo 10-12hr		(50)
embryo 12-14hr		(50)
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		(28)
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		(39)
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(41)
embryo 02-04hr		(57)
embryo 04-06hr		(42)
embryo 06-08hr		32
embryo 08-10hr		(52)
embryo 10-12hr		(50)
embryo 12-14hr		(50)
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		(39)
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		41
embryo 02-04hr		57
embryo 04-06hr		42
embryo 06-08hr		32
embryo 08-10hr		52
embryo 10-12hr		50
embryo 12-14hr		50
embryo 14-16hr		4
embryo 16-18hr		22
embryo 18-20hr		11
embryo 20-22hr		12
embryo 22-24hr		25
larva L1		7
larva L2		12
larva L3 12hr old		7
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		22
white prepupae new		28
white prepupae 12hr		26
white prepupae 24hr		25
pupae 2d postWPP		23
pupae 3d postWPP		12
pupae 4d postWPP		2
adult male 01day		7
adult male 05day		5
adult male 30day		2
adult female 01day		3
adult female 05day		39
adult female 30day		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		139
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		187
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(139)
Schneider line 2 Sg4		(67)
embryonic 1182-4H		9
embryonic GM2		(61)
embryonic Kc167		(187)
embryonic S1		9
embryonic S3		(60)
leg disc CME L1		19
wing disc CME-W2		(68)
wing disc ML-DmD8		(52)
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		(31)
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		(48)
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		(83)
mixed discs ML-DmD4-c1		(40)
CNS ML-DmBG1-c1		(27)
CNS ML-DmBG2-c2		(69)
tumorous blood cells mbn2		(57)
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(139)
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		(187)
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		139
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		187
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		139
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		187
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(139)
Schneider line 2 Sg4		(67)
embryonic 1182-4H		9
embryonic GM2		(61)
embryonic Kc167		(187)
embryonic S1		9
embryonic S3		(60)
leg disc CME L1		19
wing disc CME-W2		(68)
wing disc ML-DmD8		(52)
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		(48)
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		(83)
mixed discs ML-DmD4-c1		(40)
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		(69)
tumorous blood cells mbn2		(57)
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		139
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		(187)
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		139
Schneider line 2 Sg4		67
embryonic 1182-4H		9
embryonic GM2		61
embryonic Kc167		187
embryonic S1		9
embryonic S3		60
leg disc CME L1		19
wing disc CME-W2		68
wing disc ML-DmD8		52
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		17
wing disc ML-DmD21		31
wing disc ML-DmD32		22
haltere disc ML-DmD17-c3		48
eye-antennal disc ML-DmD11		17
antennal disc ML-DmD20-c5		83
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		27
CNS ML-DmBG2-c2		69
tumorous blood cells mbn2		57
ovary fGS/OSS		7
ovary OSC		16
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		(45)
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		(56)
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(45)
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		(45)
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		(56)
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(45)
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		3
heat shock, 4-day adult		15
Cadmium 50 mM 6 hrs, larvae L3		8
Cadmium 50 mM 12 hrs, larvae L3		23
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		45
Copper 0.5 mM 12 hrs, larvae L3		3
Copper 15 mM 48 hrs, 4-day adult		56
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		17
Ethanol 2.5% 3 hrs, larvae L3		23
Ethanol 5% 3 hrs, larvae L3		13
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		45
Caffeine 25 mg/ml 48 hrs, 4-day adult		11
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		12
Rotenone 8 μg 12 hrs, larvae L3		5
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD29015

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0033000

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

HDC07650;CG14464-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG14464	Class	Mutagen	Stocks	Known lesion
CG14464^EY11932			1	--
CG14464^EY12246		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG14464	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Disrupted in

Df(2R)M41A2

(Myster et al., 2004)

Df(2R)M41A8

(Myster et al., 2004)

Df(2R)M41A10

(Myster et al., 2004)

Df(2R)Nipped-D

(Myster et al., 2004)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}CG14464^EY11932

P{EPgy2}CG14464^EY12246

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

There is no information supporting a biological process, cellular component or molecular function term for this gene.

(Based on a review of available data before: 2006)

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG14464 - egg

experimental knowledge based

(Guruharsha et al., 2011)

CG14464 - wde

experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting

(Guruharsha et al., 2011, Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG14464 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

78257

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0033000

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

3355132

Orthologs

OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG69344P

Dipteran inclusive ortholog search

EOG6QVCNQ

Insect inclusive ortholog search

EOG64XHDV

Arthropod inclusive ortholog search

EOG6ZGMWF

Metazoa inclusive ortholog search

EOG68SVQ2

Orthologs in Drosophila Species (EOG69344P)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\CG14464

Drosophila virilis

Dvir\GJ17647

Drosophila grimshawi

Dgri\GH11310

Orthologs in non-Drosophila Dipterans (EOG6QVCNQ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL011710

Anopheles gambiae

Malaria mosquito

Agam\AGAP006763

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ008990

Orthologs in non-Dipteran Insects (EOG64XHDV)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB43844

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG015711

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH19751

Atta cephalotes

Leafcutter ant

Acep\ACEP15471

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO13093

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL19182

Linepithema humile

Argentine ant

Lhum\LH13462

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB18116

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI34264

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI003642

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI52815

Bombyx mori

Silkmoth

Bmor\BGIBMGA003674

Pediculus humanus

Human body louse

Phum\PHUM390120

Tribolium castaneum

Red flour beetle

Tcas\TC012084

Orthologs in non-Insect Arthropods (EOG6ZGMWF)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\RGD1565983

Ixodes scapularis

Deer tick

Isca\ISCW009805

Orthologs in non-Arthropod Metazoa (EOG68SVQ2)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\B0336.5

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_015405gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_025531gn

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000032499

Xenopus tropicalis

Western clawed frog

Xtro\LOC100127699

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000024460

Gallus gallus

Domestic chicken

Ggal\C5H11orf46

Mus musculus

House mouse

Mmus\Arl14ep

Mus musculus

House mouse

Mmus\Gm949

Rattus norvegicus

Norway rat

Rnor\LOC685394

Rattus norvegicus

Norway rat

Rnor\Arl14ep

Homo sapiens

Human

Hsap\ARL14EP

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\ARL14EP

AAA Orthologs (0) based on analysis using Dmel annotation version 4.3

No orthologs identified

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

Bloomington

24088

C(1;Y)1, y¹; P{EPgy2}CG14464^EY12246/CyO

20829

y¹ w^67c23; P{EPgy2}CG14464^EY11932 P{EPgy2}Uba1^EY11932/CyO

Genomic Clones ( 1 )

BACR03I06

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 47 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD29015

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0033000

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

3355132

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG14464 BcDNA:LD29015

(FlyBase, 1996-)

Source for merge of: CG14464 CG40285

(Drosophila Heterochromatin Genome Project, 2004)

Additional comments

Other Comments

Annotation CG14464 transiently renamed CG40285 in release 3.1 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_001043001

RefSeq (Proteins)

•

NP_001036466

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

3355132

UniProtKB/TrEMBL

•

Other Crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LD29015

Linkouts

BioGRID - A database of protein and genetic interactions

•

78257

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0033000

DRSC - Results from RNAi screens.

•

FBgn0033000

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0033000

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

HDC07650;CG14464-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0033000

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

3355132

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

3355132

modMine - Data generated by the modENCODE project.

•

FBgn0033000

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

BcDNA:LD29015

CG14464

(Hollien and Weissman, 2006, Hollien and Weissman, 2006, FlyBase Curators, 2008, Spresser et al., 2008)

CG40285

(Marygold et al., 2005, Dimitri et al., 2005, Myster et al., 2004, Giot et al., 2003, Rossi et al., 2007)

Name Synonym

Secondary FlyBase IDs

FBan0014464
FBgn0058285
FBgn0063147

References ( 26 )

Generate a list of

All references relating to this gene ( 26 )

List References by type

Recent research papers ( 1 )

Weber et al., 2012, PLoS ONE 7(4): e34745: Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073]

Show all research papers ...

Recent reviews (0)

All reviews listed in FlyBase were published before 2011

Show reviews ...