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Gene Dmel\CG10395

General Information
Symbol	Dmel\CG10395	Species	D. melanogaster
Name		Annotation symbol	CG10395
Feature type	protein_coding_gene	FlyBase ID	FBgn0033019
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	41E5-41E5	Sequence location	2R:1,237,998..1,239,477 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10395 (FBgn0033019). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: PAPA-1-like conserved region; Zinc finger, HIT-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1629101_a_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10395. Gene sequence location is 2R:1237998..1239477.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN28286 HFA04840
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 41E5-41E5   Limits computationally determined from genome sequence between P{PZ}vlc07022&P{lacW}l(2)09851k08138 and P{PZ}l(2)0985109851&P{lacW}Src42Ak10108
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10395 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone LD20432 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10395-RA FBtr0086087  NM_136323   1422   313
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10395-PA   FBpp0085423   36.3   313   9.91     NP_610167   AAG22340
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, HIT-type (IPR007529) PAPA-1-like conserved region (IPR006880)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438579   AA540666   AE013599 AAG22340   AW942564   AY061289 AAL28837   BI483347   BI483440   BI486532   BI487192   BP544134   BP544135   BT023754   BT030779   CO178151   CO183463   CO192283   CO264710   CO287307   EC058262   EC198531   EL875892   EL876018   EL876019   GH762280   GH767977
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95RL9 A1Z6E8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033019    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033019 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033019 expression level Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1297) embryo 02-04hr  (1339) embryo 04-06hr  (1210) embryo 06-08hr  (852) embryo 08-10hr  (1037) embryo 10-12hr  (655) embryo 12-14hr  (871) embryo 14-16hr  (166) embryo 16-18hr  (306) embryo 18-20hr  (142) embryo 20-22hr  (170) embryo 22-24hr  (349) larva L1  (129) larva L2  (244) larva L3 12hr old  (135) larva L3 puffstage 1-2  (193) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  (587) white prepupae new  (613) white prepupae 12hr  (467) white prepupae 24hr  (522) pupae 2d postWPP  (369) pupae 3d postWPP  (217) pupae 4d postWPP    35 adult male 01day  (171) adult male 05day  (111) adult male 30day    96 adult female 01day  (174) adult female 05day  (990) adult female 30day  (664) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033019 expression level Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1297) embryo 02-04hr  (1339) embryo 04-06hr  (1210) embryo 06-08hr  (852) embryo 08-10hr  (1037) embryo 10-12hr  (655) embryo 12-14hr  (871) embryo 14-16hr  (166) embryo 16-18hr  (306) embryo 18-20hr  142 embryo 20-22hr  (170) embryo 22-24hr  (349) larva L1  129 larva L2  (244) larva L3 12hr old  135 larva L3 puffstage 1-2  (193) larva L3 puffstage 3-6  (267) larva L3 puffstage 7-9  (587) white prepupae new  (613) white prepupae 12hr  (467) white prepupae 24hr  (522) pupae 2d postWPP  (369) pupae 3d postWPP  (217) pupae 4d postWPP    35 adult male 01day  (171) adult male 05day  111 adult male 30day    96 adult female 01day  (174) adult female 05day  (990) adult female 30day  (664) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1297 embryo 02-04hr    1339 embryo 04-06hr    1210 embryo 06-08hr    852 embryo 08-10hr    1037 embryo 10-12hr    655 embryo 12-14hr    871 embryo 14-16hr    166 embryo 16-18hr    306 embryo 18-20hr    142 embryo 20-22hr    170 embryo 22-24hr    349 larva L1    129 larva L2    244 larva L3 12hr old    135 larva L3 puffstage 1-2    193 larva L3 puffstage 3-6    267 larva L3 puffstage 7-9    587 white prepupae new    613 white prepupae 12hr    467 white prepupae 24hr    522 pupae 2d postWPP    369 pupae 3d postWPP    217 pupae 4d postWPP    35 adult male 01day    171 adult male 05day    111 adult male 30day    96 adult female 01day    174 adult female 05day    990 adult female 30day    664 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033019    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033019 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, adult salivary gland, larval trachea, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033019 expression level Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033019 expression level Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    234.075 Larval Midgut    49.1 Larval Hindgut    94.5 Larval Malpighian Tubules    125.3 Larval Fat Body    88.7 Larval Salivary Gland    82.7 Larval Trachea    124.525 Larval Carcass    73.2 Adult Head    120.7 Adult Eye    114.2 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    277.5 Adult Crop    101.8 Adult Midgut    56.9 Adult Hindgut    71.6 Adult Malpighian Tubules    53.9 Adult Fat Body    79.5 Adult Salivary Gland    101.6 Adult Heart    61.025 Adult VirginFemale Spermatheca    68.3 Adult InseminatedFemale Spermatheca    65 Adult Ovary    466.6 Adult Testis    27.8 Adult Male Accessory Gland    140.9 Adult Carcass    66 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    120.7   NA  Eye    114.2   NA  Brain    262.1   234.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    277.5   NA  Crop    101.8   49.1  Midgut    56.9   94.5  Hindgut    71.6   125.3  Malpighian Tubules    53.9   88.7  Fat Body    79.5   82.7  Salivary Gland    101.6   NA  Heart    61.025   124.525  Trachea    NA   NA  VirginFemale Spermatheca    68.3   NA  InseminatedFemale Spermatheca    65   NA  Ovary    466.6   NA  Testis    27.8   NA  Male Accessory Gland    140.9   73.2  Carcass    66 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033019 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10395-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG10395GD6969 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG10395GD6969 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG10395GD6969
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG10395 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10395 Class Mutagen Stocks Known lesion CG10395GD6969 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10395KK108286 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6969} NA P{KK108286} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10395 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61402 DroID - A comprehensive database of gene and protein interactions. • FBgn0033019 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35490
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20009 Dere\GG23156 Dgri\GH23731 Dmoj\GI18879 Dper\GL11052 Dpse\GA10297 Dsec\GM11102 Dsim\GD10370 Dvir\GJ21913 Dwil\GK21947 Dyak\GE11367
Curated drosophilid orthologs	Dpse\GA10297
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL014237-PA Aedes aegypti (mosquito) AGAP006175-PA Anopheles gambiae (mosquito) XP_001951228.1 Acyrthosiphon pisum (pea aphid) 123786 Branchiostoma floridae (lancelet) 125526 Branchiostoma floridae (lancelet) ENSBTAP00000002404 Bos taurus (bovine) ENSCAFP00000012489 Canis familiaris (dog) ENSCPOP00000011450 Cavia porcellus (guinea pig) 226354 Capitella spl (polychaete worm) 5569 Daphnia pulex (daphnia) ENSDARP00000085532 Danio rerio (zebra fish) ENSECAP00000008052 Equus caballus (horse) ENSGACP00000025220 Gymnopilus aculeatus (mushroom) ENSP00000233331 Homo sapiens (human) 104239 Lottia gigantea (owl limpet) ENSMODP00000006126 Monodelphis domestica (gray opossum) ENSMMUP00000003670 Macaca mulatta (rhesus monkey) ENSMUSP00000109568 Mus musculus (house mouse) 206717 Nematostella vectensis (starlet anemone) XP_001606338.1 Nasonia vitripennis (wasp) ENSORLP00000009898 Oryzias latipes (japanese killifish) PHUM007611-PA Pediculus humanus (human body louse) ENSPPYP00000013686 Pongo pygmaeus (orangutan) ENSPTRP00000020744 Pan troglodytes (chimpanzee) ENSRNOP00000011921 Rattus norvegicus (norway rat) 5008792 Sorghum bicolor (sorghum) XP_001178362.1 Strongylocentrotus purpuratus (purple sea urchin) 59046 Trichoplax adhaerens (metazoa) ENSTNIP00000005831 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000005243 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11221 LH19342 ISCW019116 FBgn0229180 FBgn0223932 FBgn0209028 FBgn0182142 FBgn0166047 JGI_V11_5569 FBgn0070355 FBgn0148662 FBgn0141618 FBgn0131188 FBgn0129197 FBgn0115308 FBgn0097016 BGIBMGA006778 ACYPI002327 ACYPI000993 GB10958 AGAP006175 AAEL014237 PB25607 PHUM216230 GLEAN_11013
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v100578 P{KK108286}VIE-260B v31244 w1118; P{GD6969}v31244
Genomic Clones ( 2 )
	BACR02D22 BACR32F22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 19 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD20432 RE66224
Other clones	FI01442
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD12386 RE66341 RE69974 RE70711
Other clones	31165 CK01.69C.G1 EC25763 EC33474 EK055525 EK065525 EK140111 FGC024C05 IP05793 IP05893 RP001010349 RP001040387
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033019 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35490
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136323 RefSeq (Proteins) • NP_610167 DDBJ / EMBL / GenBank • AA540666 AAG22340 AAG22340.2 AAL28837 AAM68377.1 AW942564 AY061289 BI483347 Entrez Gene - A searchable database of RefSeq genes. • 35490 UniProtKB/TrEMBL • A1Z6E8 Q95RL9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, HIT-type (IPR007529) PAPA-1-like conserved region (IPR006880)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61402 DroID - A comprehensive database of gene and protein interactions. • FBgn0033019 DRSC - Results from RNAi screens. • FBgn0033019 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033019 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10395-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033019 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35490 InParanoid A subset of ortholog calls from InParanoid. • AAEL014237-PA Aedes aegypti (mosquito) AGAP006175-PA Anopheles gambiae (mosquito) XP_001951228.1 Acyrthosiphon pisum (pea aphid) 123786 Branchiostoma floridae (lancelet) 125526 Branchiostoma floridae (lancelet) ENSBTAP00000002404 Bos taurus (bovine) ENSCAFP00000012489 Canis familiaris (dog) ENSCPOP00000011450 Cavia porcellus (guinea pig) 226354 Capitella spl (polychaete worm) 5569 Daphnia pulex (daphnia) ENSDARP00000085532 Danio rerio (zebra fish) ENSECAP00000008052 Equus caballus (horse) ENSGACP00000025220 Gymnopilus aculeatus (mushroom) ENSP00000233331 Homo sapiens (human) 104239 Lottia gigantea (owl limpet) ENSMODP00000006126 Monodelphis domestica (gray opossum) ENSMMUP00000003670 Macaca mulatta (rhesus monkey) ENSMUSP00000109568 Mus musculus (house mouse) 206717 Nematostella vectensis (starlet anemone) XP_001606338.1 Nasonia vitripennis (wasp) ENSORLP00000009898 Oryzias latipes (japanese killifish) PHUM007611-PA Pediculus humanus (human body louse) ENSPPYP00000013686 Pongo pygmaeus (orangutan) ENSPTRP00000020744 Pan troglodytes (chimpanzee) ENSRNOP00000011921 Rattus norvegicus (norway rat) 5008792 Sorghum bicolor (sorghum) XP_001178362.1 Strongylocentrotus purpuratus (purple sea urchin) 59046 Trichoplax adhaerens (metazoa) ENSTNIP00000005831 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000005243 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35490 modMine - Data generated by the modENCODE project. • FBgn0033019 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11221 LH19342 ISCW019116 FBgn0229180 FBgn0223932 FBgn0209028 FBgn0182142 FBgn0166047 JGI_V11_5569 FBgn0070355 FBgn0148662 FBgn0141618 FBgn0131188 FBgn0129197 FBgn0115308 FBgn0097016 BGIBMGA006778 ACYPI002327 ACYPI000993 GB10958 AGAP006175 AAEL014237 PB25607 PHUM216230 GLEAN_11013
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10395 (Rossi et al., 2007, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
	FBan0010395
References ( 14 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Rossi et al., 2007, Genetics 175(2): 595--607 Cytogenetic and molecular characterization of heterochromatin gene models in Drosophila melanogaster. [FBrf0192814] Myster et al., 2004, Genetics 166(2): 807--822 Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. [FBrf0174713] Corradini et al., 2003, Chromosoma 112(1): 26--37 FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements. [FBrf0160459]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Drosophila Heterochromatin Genome Project, 2006, Release 5.1 of the annotated Drosophila melanogaster heterochromatin. Release 5.1 of the annotated Drosophila melanogaster heterochromatin. [FBrf0188763]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]