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Gene Dmel\tbce

General Information
Symbol	Dmel\tbce	Species	D. melanogaster
Name	tubulin-specific chaperone E	Annotation symbol	CG7861
Feature type	protein_coding_gene	FlyBase ID	FBgn0033055
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	42A8-42A8	Sequence location	2R:1,930,037..1,932,469 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene tubulin-specific chaperone E is referred to in FlyBase by the symbol Dmel\tbce (CG7861, FBgn0033055). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; microtubule polymerization; regulation of synaptic growth at neuromuscular junction; neurogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; NMJ bouton; embryonic/larval neuromuscular junction; longitudinal connective; microtubule. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: CAP Gly-rich domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640333_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of tbce. Gene sequence location is 2R:1930037..1932469.
User Contributed Data
	Beta version, feedback welcome
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 42A8-42A8   Limits computationally determined from genome sequence between P{PZ}l(2)0985109851&P{lacW}Src42Ak10108 and P{lacW}l(2)k09848k09848&P{EP}EP407
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\tbce for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) tbce-RB FBtr0085974  NM_206025   2080   523 tbce-RC FBtr0335286  NM_136353   2144   523
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein tbce-PB   FBpp0085327   59.4   523   6.58     NP_995747   AAS64773 tbce-PC   FBpp0307274   59.4   523   6.58     NP_610197   AAF57288
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • CAP Gly-rich domain (IPR000938)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA697397   AA697401   AA803472   AA950128   AE013599 AAF57288   AE013599 AAS64773   AI109282   AI113537   AI518951   AY118314 AAM48343   BG632433   BI141815   BI165425   BI169541   BI214815   BI236379   BI236691   BI236771   BI237007   BI237352   BI239876   BI356976   BI363708   BI366006   BI590051   BI627334   BT044200   CA804174   CO182917   CO196407   CO295845   CO307116   CO308522   CO311967   CO320931   CO342417   CZ482512   EC064088   EC066267   EC204239   EC213138   EC239292   EC240188   EC240699   EC248324   EC249376   EC250034   EC254838   EC254845   GH942207   GH942625   GH944796   GH947308   GH947764   GH948617   GH950045   GH950220   GH950438   GH953683   GH954650   GH956248   GH961392   GH961669   GH961719   GH961971   GH962390   GH962421   GH964434   GH965270   GH968399   GH970181   GH972957   GH974720   GH976514   GH976686   GH977727   GH978600   GH979244   GH979298   GH981714   GH981839   GH983661   GH983943   GH984494
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A1Z6J5 A1Z6J4 Q8MT85
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Jin et al., 2009) ventral nerve cord   (Jin et al., 2009) embryonic/larval muscle system   (Jin et al., 2009) larval stage   embryonic/larval epidermis   (Jin et al., 2009) third instar larval stage   embryonic/larval central nervous system   (Jin et al., 2009) embryonic/larval muscle system   (Jin et al., 2009) Comment:perinuclear enrichment seen
Additional Descriptive Data
	tbce is ubiquitously expressed in embryos with particular enrichment in the neuromusculature. In third instar larvae, weak expression is observed in muscles, central neurons, and peripheral axons and strong expression is seen in the epidermis. (Jin et al., 2009)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cytoplasm inferred from direct assay (Jin et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    177.25 Larval Midgut    98.9 Larval Hindgut    131.2 Larval Malpighian Tubules    194.3 Larval Fat Body    90.8 Larval Salivary Gland    213.1 Larval Trachea    137.25 Larval Carcass    151.825 Adult Head    144 Adult Eye    139.8 Adult Brain    261.7 Adult Thoracic-Abdominal Ganglion    295 Adult Crop    172.5 Adult Midgut    91.7 Adult Hindgut    144 Adult Malpighian Tubules    134.4 Adult Fat Body    96 Adult Salivary Gland    113.4 Adult Heart    71.7 Adult VirginFemale Spermatheca    114.5 Adult InseminatedFemale Spermatheca    133.4 Adult Ovary    207.7 Adult Testis    231 Adult Male Accessory Gland    49.9 Adult Carcass    118 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    144   NA  Eye    139.8   NA  Brain    261.7   177.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    295   NA  Crop    172.5   98.9  Midgut    91.7   131.2  Hindgut    144   194.3  Malpighian Tubules    134.4   90.8  Fat Body    96   213.1  Salivary Gland    113.4   NA  Heart    71.7   137.25  Trachea    NA   NA  VirginFemale Spermatheca    114.5   NA  InseminatedFemale Spermatheca    133.4   NA  Ovary    207.7   NA  Testis    231   NA  Male Accessory Gland    49.9   151.825  Carcass    118 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    22 central nervous system, larvae L3    13 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    10 head, virgin 20-day female    7 head, mated 1-day female    8 head, mated 4-day female    9 head, mated 20-day female    6 head, mated 1-day male    17 head, mated 4-day male    15 head, mated 20-day male    17 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    8 digestive system, 4-day adult    6 digestive system, 20-day adult    6 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    4 carcass, larvae L3 wandering    15 carcass, 1-day adult    8 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    22 ovary, mated 4-day female    19 testis, mated 4-day male    24 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (30) embryo 02-04hr  (36) embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr  26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  30 embryo 02-04hr  (36) embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr  26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    36 embryo 04-06hr    25 embryo 06-08hr    23 embryo 08-10hr    22 embryo 10-12hr    22 embryo 12-14hr    19 embryo 14-16hr    12 embryo 16-18hr    13 embryo 18-20hr    11 embryo 20-22hr    12 embryo 22-24hr    15 larva L1    13 larva L2    11 larva L3 12hr old    7 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    22 white prepupae new    21 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    21 pupae 3d postWPP    15 pupae 4d postWPP    11 adult male 01day    19 adult male 05day    21 adult male 30day    19 adult female 01day    12 adult female 05day    20 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    114 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (114) Schneider line 2 Sg4    23 embryonic 1182-4H  26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2  (33) ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (114) Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    114 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    114 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (114) Schneider line 2 Sg4    23 embryonic 1182-4H  26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2  (33) ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  114 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    114 Schneider line 2 Sg4    23 embryonic 1182-4H    26 embryonic GM2    17 embryonic Kc167    14 embryonic S1    22 embryonic S3    23 leg disc CME L1    16 wing disc CME-W2    20 wing disc ML-DmD8    17 wing disc ML-DmD9    18 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    21 wing disc ML-DmD32    20 haltere disc ML-DmD17-c3    25 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    18 mixed discs ML-DmD4-c1    25 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    33 ovary fGS/OSS    20 ovary OSC    18 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    10 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • GM13256 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033055 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7861-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for tbce Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal tbceGD10779 lethal | embryonic stage (with tbceLH15) tbceZ0241 lethal | embryonic stage (with tbceZ0241) tbceLH15 lethal | pupal stage, with Scer\GAL4elav-C155 tbcedsRNA.Scer\UAS.cJa viable, with Scer\GAL4C57 tbcedsRNA.Scer\UAS.cJa Other Phenotypes Allele locomotor behavior defective | larval stage, with Scer\GAL4C57 tbcedsRNA.Scer\UAS.cJa tbceScer\UAS.cJa locomotor behavior defective | larval stage, with Scer\GAL4elav-C155 tbcedsRNA.Scer\UAS.cJa tbceScer\UAS.cJa neuroanatomy defective | embryonic stage tbceLH15 tbceZ0241 neuroanatomy defective | larval stage tbceGD10779 neuroanatomy defective | larval stage, with Scer\GAL4C57 tbcedsRNA.Scer\UAS.cJa tbceScer\UAS.cJa neuroanatomy defective | larval stage, with Scer\GAL4elav-C155 tbcedsRNA.Scer\UAS.cJa Phenotype manifest in Allele embryonic/larval neuroblast | larval stage tbceGD10779 embryonic/larval neuromuscular junction, with Scer\GAL4C57 tbceScer\UAS.cJa tbcedsRNA.Scer\UAS.cJa embryonic/larval neuromuscular junction, with Scer\GAL4elav-C155 tbcedsRNA.Scer\UAS.cJa ganglion mother cell | larval stage tbceGD10779 longitudinal connective tbceZ0241 tbceLH15 microtubule, with Scer\GAL4C57 tbceScer\UAS.cJa tbcedsRNA.Scer\UAS.cJa microtubule (with Df(2R)ED1484) tbceZ0241 microtubule & neuromuscular junction, with Scer\GAL4elav-C155 tbceScer\UAS.cJa tbcedsRNA.Scer\UAS.cJa NMJ bouton, with Scer\GAL4C57 tbceScer\UAS.cJa tbcedsRNA.Scer\UAS.cJa NMJ bouton, with Scer\GAL4elav-C155 tbcedsRNA.Scer\UAS.cJa ventral nerve cord tbceZ0241 tbceLH15
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of tbce Class Mutagen Stocks Known lesion tbcef00024 piggyBac transposase 2 -- tbceLH15 Delta2-3 1 Yes tbceZ0241 ethyl methanesulfonate 1 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of tbce Class Mutagen Stocks Known lesion tbcedsRNA.Scer\UAS.cJa in vitro construct - regulatory fusion in vitro construct - RNAi 1 Yes tbceKK100119 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes tbceScer\UAS.cJa in vitro construct - regulatory fusion 1 Yes tbceGD10779 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes tbceNIG.7861R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7085 (Ryder, 2004.4.26) Df(2R)tbceLH15 (Jin et al., 2009)
Partially disrupted in	Df(2R)tbceLH15 (Jin et al., 2009)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.7861R} NA P{UAS-tbce.J} NA P{UAS-tbce.RNAi.J} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}tbcef00024 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
microtubule polymerization inferred from genetic interaction with spas (Jin et al., 2009) inferred from mutant phenotype (Jin et al., 2009) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011) neuromuscular synaptic transmission inferred from mutant phenotype (Jin et al., 2009) regulation of synaptic growth at neuromuscular junction inferred from mutant phenotype (Jin et al., 2009)
Cellular Component
CV term Evidence References
cytoplasm inferred from direct assay (Jin et al., 2009)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
tubulin complex assembly inferred from sequence or structural similarity with NCBI_gi:4507375 (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions tbce allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0033055 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35532
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG683DQ6 Dipteran inclusive ortholog search EOG6JWVNT Insect inclusive ortholog search EOG6Q57JQ Arthropod inclusive ortholog search EOG6BK3K3 Metazoa inclusive ortholog search EOG6NGVF0
Orthologs in Drosophila Species (EOG683DQ6)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\tbce     Drosophila simulans   Dsim\GD10392 Y   Drosophila sechellia   Dsec\GM16532 Y   Drosophila erecta   Dere\GG23192 Y   Drosophila yakuba   Dyak\GE20681 Y   Drosophila ananassae   Dana\GF11041 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20640 Y   Drosophila persimilis   Dper\GL16698 Y   Drosophila willistoni   Dwil\GK21325 Y   Drosophila virilis   Dvir\GJ21436 Y   Drosophila mojavensis   Dmoj\GI18365 Y   Drosophila grimshawi   Dgri\GH20927 Y
Orthologs in non-Drosophila Dipterans (EOG6JWVNT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014111   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011067   Anopheles gambiae Malaria mosquito  Agam\AGAP010770   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004460
Orthologs in non-Dipteran Insects (EOG6Q57JQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC724808   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004273   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17861   Atta cephalotes Leafcutter ant  Acep\ACEP21559   Camponotus floridanus Florida carpenter ant  Cflo\CFLO18868   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17941   Linepithema humile Argentine ant  Lhum\LH15808   Pogonomyrmex barbatus Red harvester ant  Pbar\PB10800   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009010   Bombyx mori Silkmoth  Bmor\BGIBMGA000149   Pediculus humanus Human body louse  Phum\PHUM136500   Tribolium castaneum Red flour beetle  Tcas\TC030612
Orthologs in non-Insect Arthropods (EOG6BK3K3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\pomc   Daphnia pulex Water flea  Dpux\cytb   Ixodes scapularis Deer tick  Isca\ISCW012126   Ixodes scapularis Deer tick  Isca\ISCW012125
Orthologs in non-Arthropod Metazoa (EOG6NGVF0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\K07H8.1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023279gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004522gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025290gn   Danio rerio Zebrafish  Drer\tbce   Xenopus tropicalis Western clawed frog  Xtro\tbce   Gallus gallus Domestic chicken  Ggal\TBCE   Mus musculus House mouse  Mmus\Tbce   Rattus norvegicus Norway rat  Rnor\Tbce   Homo sapiens Human  Hsap\TBCE
Human Orthologs (1)
Gene OMIM HGNC Hsap\TBCE
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10392 Drosophila sechellia Dsec\GM16532 Drosophila erecta Dere\GG23192 Drosophila yakuba Dyak\GE20681 Drosophila ananassae Dana\GF11041 Drosophila pseudoobscura pseudoobscura Dpse\GA20640 Drosophila persimilis Dper\GL16698 Drosophila willistoni Dwil\GK21325 Drosophila virilis Dvir\GJ21436 Drosophila mojavensis Dmoj\GI18365 Drosophila grimshawi Dgri\GH20927
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	18286 w1118; PBac{WH}tbcef00024/CyO 34536 w1118; P{UAS-tbce.J}3/TM6B, Tb1 34535 w*; tbceLH15/CyO, P{GAL4-Kr.C}DC3, P{UAS-GFP.S65T}DC7 34537 w*; wgSp-1/CyO; P{UAS-tbce.RNAi.J}3/TM6B, Tb1 34534 tbceZ0241 cn1 bw1/CyO, P{GAL4-Kr.C}DC3, P{UAS-GFP.S65T}DC7
Harvard	- PBac{WH}tbcef00024
VDRC	v105246 P{KK100119}VIE-260B
Genomic Clones ( 2 )
	BACR13P06 BACR39E09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 78 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM13256
Other clones	FI05242
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH09869 HL02405 HL02413 LD28663 RE05324 RE10749 RE20944 RE32429 RE32785 RE32882 RE33148 RE33569 RE36483 RE43303 RE48633 RE51433 RH03609 RH68618 SD15743
Other clones	78065 81614 104047 148002 155708 165414 165424 184090 214349.5 214441.46 CK01.21A.G11 CK01.115B.B10 EC24279 EK004129 EK211739 EK227531 EK253641 EK258613 EK288829 EP14862 ESG0112b.B21_G06 GH08424 RP004082768 RP004111049 RP004126171 RP004172785 RP004176061 RP004177800 RP004195010 RP004197947 RP004204543 RP004205303 RP004206815 RP004210976 RP004227801 RP004228712 RP004236224 RP004251818 RP004252189 RP004258695 RP004258835 RP004270486 RP004280903 RP004312626 RP004317611 RP004358256 RP004389590 RP004430853 RP004455690 RP004494672 RP004503874 RP004525189 RP004525895 RP004529751 RP004532256 RP004532763 RP004535123
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033055 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35532
Antibody Information
	monoclonal (Jin et al., 2009)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: tbce CG7861 (Jin et al., 2009)
Source for database merge of
Additional comments
Other Comments
	One of 42 Drosophila genes identified as being most likely to reveal molecular and cellular mechanisms of nervous system development or plasticity relevant to human Mental Retardation disorders. (Inlow and Restifo, 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136353 NM_206025 RefSeq (Proteins) • NP_610197 NP_995747 DDBJ / EMBL / GenBank • AA803472 AAF57288 AAM48343 AAS64773 AI518951 AY118314 CZ482512 Entrez Gene - A searchable database of RefSeq genes. • 35532 UniProtKB/TrEMBL • A1Z6J4 A1Z6J5 Q8MT85
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • CAP Gly-rich domain (IPR000938) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM13256
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0033055 DRSC - Results from RNAi screens. • FBgn0033055 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033055 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7861-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033055 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35532 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/tbce_tubulinshaperone.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35532 modMine - Data generated by the modENCODE project. • FBgn0033055
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG7861 (Immonen and Ritchie, 2012, Jin et al., 2009, Keleman et al., 2009.8.5, Bhutkar et al., 2007, Japanese National Institute of Genetics, 2012.5.21) tbce (Jin et al., 2009, Jin and Zhang, 2011.3.11)
Name Synonym	tubulin-specific chaperone E   Tubulin-specific chaperone E (Jin et al., 2009)
Secondary FlyBase IDs
References ( 19 )
Research paper	Immonen and Ritchie, 2012, Proc. Biol. Sci. 279(1732): 1359--1365 The genomic response to courtship song stimulation in female Drosophila melanogaster. [FBrf0217554] Jin et al., 2009, Development 136(9): 1571--1581 Drosophila Tubulin-specific chaperone E functions at neuromuscular synapses and is required for microtubule network formation. [FBrf0209976] Bhutkar et al., 2007, Genome Res. 17(12): 1880--1887 Genome-scale analysis of positionally relocated genes. [FBrf0202666] Inlow and Restifo, 2004, Genetics 166(2): 835--881 Molecular and comparative genetics of mental retardation. [FBrf0174714]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Jin and Zhang, 2011.3.11, UAS-tbce and UAS-tbceRNAi insertions from Shan Jin and Yong Zhang. UAS-tbce and UAS-tbceRNAi insertions from Shan Jin and Yong Zhang. [FBrf0213245] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]