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Gene Dmel\CG3409

General Information
Symbol	Dmel\CG3409	Species	D. melanogaster
Name		Annotation symbol	CG3409
Feature type	protein_coding_gene	FlyBase ID	FBgn0033095
Gene Model Status	Current	Stock availability	12 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	42C5-42C6	Sequence location	2R:2,587,200..2,603,397 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3409 (FBgn0033095). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: monocarboxylic acid transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 14 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval Malpighian tubules, larval/adult fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. Gene sequence location is 2R:2587200..2603397.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 42C5-42C6   Limits computationally determined from genome sequence between P{lacW}geminink14019&P{PZ}Adf101349 and P{lacW}ublk03203&P{PZ}CG328709967
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3409 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. miRNA(s) located within the transcribed region of this gene. Annotated transcripts do not represent all supported alternative splices within 5' UTR. Gene model reviewed during 5.48 5' UTR contains an ORF that is conserved among close Drosophila species (potential peptide 109 aa in length; initial methionine is conserved).
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3409-RA FBtr0086140  NM_136386   5083   894 CG3409-RB FBtr0302166  NM_001169592   5152   894 CG3409-RC FBtr0336659  NM_001273804   4496   894
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3409-PA   FBpp0085473   98.9   894   6.61     NP_610230   AAM70818 CG3409-PB   FBpp0291376   98.9   894   6.61     NP_001163063   ACZ94343 CG3409-PC   FBpp0307642   98.9   894   6.61     NP_001260733   AGB93266
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily domain (IPR020846)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141210   AA141211   AA142306   AA201774   AA950816   AE013599 AAM70818   AE013599 ACZ94343   AE013599 AGB93266   AW943057   AY069571 AAL39716   BF488675   BG635648   BI164519   BI236496   BI372138   BI373716   BI608272   BI629089   BP558845   BT083417   CK604332   CK604333   CK660637   CO183254   CO194257   CO263094   CO274506   CO278545   CO301391   CO315723   CO321121   CO326736   CO341734   CO342593   CZ466967   CZ469155   CZ483350   CZ486512   CZ486513   DN154081   DN154089   EC057088   EC083481   EC089290   EC194371   EC196797   EC198680   EC211594   EC222628   EC222945   EC228030   EC229125   EC231201   EC256072   EC256871   EC257184   EV592987
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T043
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   • cytoplasm | basal (Fisher et al., 2012) Comment:apically cleared embryonic stage 7 -- 8   hindgut anlage   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium inclusive hindgut primordium   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 11 -- 12   amnioserosa   (Fisher et al., 2012) anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) embryonic ganglion mother cell   (Fisher et al., 2012) embryonic neuroblast of ventral nerve cord primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) midline primordium   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) procephalic neuroblast   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic anal pad   (Fisher et al., 2012) embryonic brain   (Fisher et al., 2012) embryonic central brain neuron   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval Malpighian tubules, larval/adult fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8  (29) head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male  (27) head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female  (28) ovary, mated 4-day female  26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8  29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male  27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female  28 ovary, mated 4-day female  26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    13 central nervous system, pupae P8    29 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    21 head, mated 1-day female    20 head, mated 4-day female    21 head, mated 20-day female    19 head, mated 1-day male    27 head, mated 4-day male    22 head, mated 20-day male    21 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    26 digestive system, 1-day adult    14 digestive system, 4-day adult    18 digestive system, 20-day adult    14 fat body, larvae L3 wandering    12 fat body, white prepupae    16 fat body, pupae P8    13 carcass, larvae L3 wandering    16 carcass, 1-day adult    22 carcass, 4-day adult    20 carcass, 20-day adult    17 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    5 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr  (27) embryo 06-08hr  (35) embryo 08-10hr  (45) embryo 10-12hr  (33) embryo 12-14hr  (36) embryo 14-16hr  (30) embryo 16-18hr  (27) embryo 18-20hr  26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr  27 embryo 06-08hr  (35) embryo 08-10hr  (45) embryo 10-12hr  (33) embryo 12-14hr  (36) embryo 14-16hr  30 embryo 16-18hr  27 embryo 18-20hr  26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    20 embryo 02-04hr    18 embryo 04-06hr    27 embryo 06-08hr    35 embryo 08-10hr    45 embryo 10-12hr    33 embryo 12-14hr    36 embryo 14-16hr    30 embryo 16-18hr    27 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    23 larva L1    20 larva L2    16 larva L3 12hr old    12 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    10 white prepupae 24hr    12 pupae 2d postWPP    15 pupae 3d postWPP    24 pupae 4d postWPP    16 adult male 01day    17 adult male 05day    17 adult male 30day    14 adult female 01day    16 adult female 05day    17 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H  (50) embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9  (29) wing disc ML-DmD16-c3  (29) wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3  (28) eye-antennal disc ML-DmD11  (27) antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS  (38) ovary OSC  (40) ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H  (50) embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9  29 wing disc ML-DmD16-c3  29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3  28 eye-antennal disc ML-DmD11  27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS  (38) ovary OSC  (40) ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    7 embryonic 1182-4H    50 embryonic GM2    21 embryonic Kc167    11 embryonic S1    9 embryonic S3    7 leg disc CME L1    7 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    29 wing disc ML-DmD16-c3    29 wing disc ML-DmD21    4 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    12 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    6 ovary fGS/OSS    38 ovary OSC    40 ovary OSS    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    17 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    22 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    24 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_31 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • CG3409 LD30953 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033095 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3409-RA;S.C2R000135 FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG3409 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG3409GD1829 viable CG3409CB04412 Phenotype manifest in Allele
Classical Alleles ( 12 )
For All Classical Alleles Show
Allele of CG3409 Class Mutagen Stocks Known lesion CG3409NP1374 2 -- CG3409c04303 piggyBac transposase 1 -- CG3409f00873 piggyBac transposase 1 -- CG3409f03907 piggyBac transposase 1 -- CG3409KG03625 1 -- CG3409KG04517 1 -- CG3409MB04207 1 -- CG3409NP0772 1 -- CG3409NP3576 1 -- CG3409c01186 piggyBac transposase 0 -- CG3409CB04412 P-element activity 0 Yes CG3409DG03307 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3409 Class Mutagen Stocks Known lesion CG3409GD1829 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG3409NIG.3409R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1829} NA P{NIG.3409R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GB}CG3409CB04412 NA P{SUPor-P}CG3409KG03625 NA P{SUPor-P}CG3409KG04517 NA P{wHy}CG3409DG03307 NA PBac{PB}CG3409c01186 NA PBac{PB}CG3409c04303 NA PBac{WH}CG3409f00873 NA PBac{WH}CG3409f03907 NA insertion of enhancer trap P{lacW}l(2)SH2293SH2293 No insertion of enhancer trap binary system Mi{ET1}CG3409MB04207 No P{GawB}CG3409NP0772 No P{GawB}CG3409NP1374 No P{GawB}CG3409NP3576 No
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
monocarboxylic acid transmembrane transporter activity inferred from sequence or structural similarity with NCBI_gi:4759112 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG3409 - Atx2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG10077 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG13472 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG15735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG6701 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG7903 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG8021 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - CG8043 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Eb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Gapdh2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Map205 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Ns1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Rab6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - Saf-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG3409 - mts anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3409 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033095 DroID - A comprehensive database of gene and protein interactions. • FBgn0033095 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35578
Orthologs
OrthoDB Orthologs (46) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6549J1 Dipteran inclusive ortholog search EOG69GKQQ Insect inclusive ortholog search EOG66M9DN Arthropod inclusive ortholog search EOG6M0CGQ Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6549J1)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG3409     Drosophila simulans   Dsim\GD10310 Y   Drosophila sechellia   Dsec\GM20859 Y   Drosophila erecta   Dere\GG10808 Y   Drosophila yakuba   Dyak\GE24576 Y   Drosophila ananassae   Dana\GF13798 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17432 Y   Drosophila persimilis   Dper\GL10985 Y   Drosophila willistoni   Dwil\GK23138 Y   Drosophila virilis   Dvir\GJ20187 Y   Drosophila mojavensis   Dmoj\GI20236 Y   Drosophila grimshawi   Dgri\GH20145 Y
Orthologs in non-Drosophila Dipterans (EOG69GKQQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004905   Anopheles gambiae Malaria mosquito  Agam\AGAP005394   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ014208
Orthologs in non-Dipteran Insects (EOG66M9DN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC410067   Apis mellifera Western honey bee  Amel\LOC552505   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004476   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004478   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19436   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19438   Atta cephalotes Leafcutter ant  Acep\ACEP27888   Atta cephalotes Leafcutter ant  Acep\ACEP27891   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22343   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22344   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19128   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19126   Linepithema humile Argentine ant  Lhum\LH12832   Linepithema humile Argentine ant  Lhum\LH15400   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20870   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20868   Solenopsis invicta Red fire ant  Sinv\SINV16190   Solenopsis invicta Red fire ant  Sinv\SINV16182   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004437   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004938   Bombyx mori Silkmoth  Bmor\BGIBMGA003914   Bombyx mori Silkmoth  Bmor\BGIBMGA007154   Bombyx mori Silkmoth  Bmor\BGIBMGA007204   Bombyx mori Silkmoth  Bmor\BGIBMGA003955   Bombyx mori Silkmoth  Bmor\BGIBMGA003915   Pediculus humanus Human body louse  Phum\PHUM160360   Pediculus humanus Human body louse  Phum\PHUM160720   Tribolium castaneum Red flour beetle  Tcas\TC005811   Tribolium castaneum Red flour beetle  Tcas\TC006337
Orthologs in non-Insect Arthropods (EOG6M0CGQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_39459   Ixodes scapularis Deer tick  Isca\ISCW009504
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10310 Drosophila sechellia Dsec\GM20859 Drosophila erecta Dere\GG10808 Drosophila yakuba Dyak\GE24576 Drosophila ananassae Dana\GF13798 Drosophila pseudoobscura pseudoobscura Dpse\GA17432 Drosophila persimilis Dper\GL10985 Drosophila willistoni Dwil\GK23138 Drosophila virilis Dvir\GJ20187 Drosophila mojavensis Dmoj\GI20236 Drosophila grimshawi Dgri\GH20145
Stocks & Reagents
Stocks Listed in FlyBase ( 12 )
Bloomington	24296 w1118; Mi{ET1}CG3409MB04207 13606 y1 w67c23; P{SUPor-P}CG3409KG04517 13251 w1118; P{SUPor-P}CG3409KG03625/CyO, P{sevRas1.V12}FK1
Harvard	- PBac{PB}CG3409c04303 - PBac{WH}CG3409f00873 - PBac{WH}CG3409f03907
Kyoto	112657 w*; P{GawB}CG3409NP1374 103755 w*; P{GawB}CG3409NP0772 / CyO 104007 y* w*; P{GawB}CG3409NP1374 104545 y* w*; P{GawB}CG3409NP3576 / CyO, P{UAS-lacZ.UW14}UW14
VDRC	v37139 w1118; P{GD1829}v37139/TM3 v37141 w1118; P{GD1829}v37141/TM3
Genomic Clones ( 2 )
	BACR01C10 BACR07J20 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 45 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD30953
Other clones	DPiM_LD30953 MIP06944
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24182 LD04993 LP19376 RE04218 RE32557 RE59019 RE61095 RH12466 RH57896 SD13115
Other clones	12290 17816 47528 54747 58418 159124 211018 214435.58 214447.41 214569.8 CK01.2D.D1 CK01.12D.E2 CK01.18D.G8 CK01.104B.B2 CK01376 CK02180 Dmel_neb_014945_0683_3108 EC25309 EC37709 EK087437 EK114312 EK130336 EK174549 EK175226 EK180853 EK262316 EK290341 EP04530 EP13045 EP15158 FGM317D04 UT01106
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033095 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35578
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136386 NM_001169592 NM_001273804 RefSeq (Proteins) • NP_610230 NP_001163063 NP_001260733 DDBJ / EMBL / GenBank • AA950816 AAL39716 AAM70818 ACZ94343 AGB93266 AW943057 AY069571 CZ466967 CZ469155 CZ483350 CZ486512 CZ486513 Entrez Gene - A searchable database of RefSeq genes. • 35578 UniProtKB/TrEMBL • Q8T043
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196) Major facilitator superfamily domain (IPR020846) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • CG3409 LD30953
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033095 DroID - A comprehensive database of gene and protein interactions. • FBgn0033095 DRSC - Results from RNAi screens. • FBgn0033095 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033095 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3409-RA;S.C2R000135 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033095 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35578 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35578 modMine - Data generated by the modENCODE project. • FBgn0033095
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG3409 (Buszczak et al., 2007, Mosallanejad et al., 2010, Foley et al., 2010, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 4 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...