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Gene Dmel\CG11107

General Information
Symbol	Dmel\CG11107	Species	D. melanogaster
Name		Annotation symbol	CG11107
Feature type	protein_coding_gene	FlyBase ID	FBgn0033160
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43B2-43B2	Sequence location	2R:3,274,719..3,278,529 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11107 (FBgn0033160). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent helicase activity; ATP-dependent RNA helicase activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Domain of unknown function DUF1605; Helicase, C-terminal; Helicase-associated domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636354_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11107. Gene sequence location is 2R:3274719..3278529.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
FB2012_01	Sequence features BKN22152 HFA06036
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43B2-43B2   Limits computationally determined from genome sequence between P{lacW}cosk16101 and P{EP}CG1600EP398
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11107 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11107-RA FBtr0088966  NM_136425   2721   729
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11107-PA   FBpp0088040   82.7   729   7.07     NP_610269   AAF59269
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) Helicase-associated domain (IPR007502) Domain of unknown function DUF1605 (IPR011709) DEAD-like helicase (IPR014001) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202009   AA203093   AA246626   AA263561   AA264827   AA440794   AA441677   AA695018   AA696529   AA803479   AA942109   AA950488   AA951205   AA979471   AE013599 AAF59269   AI124258   AI456341   AI456571   AI456817   AI513927   AI513928   AI515504   AI518812   AI518952   AI519259   AI532452   AI532462   AI543358   AI544240   AI544404   AI546520   AI546666   AY058484 AAL13713   BF488350   BF492340   BF494051   BF496142   BF502863   BF506453   BG635520   BG635828   BH214601   BI141779   BI165220   BI166131   BI169932   BI173898   BI212555   BI227877   BI229550   BI230387   BI231612   BI231670   BI233083   BI233174   BI234190   BI234966   BI239870   BI353483   BI353602   BI354788   BI356266   BI357607   BI366984   BI368694   BI373279   BI483398   BI580244   BI637992   BI638353   CO177622   CO185060   CO194046   CO271919   CO280311   CO307963   CO312963   CO318786   CO331445   CO332039   CO344674   EC051042   EC052296   EC052557   EC053580   EC055129   EC055574   EC056661   EC058182   EC071638   EC079219   EC084783   EC202217   EC227207   EC228068   EC248431   EC255130   EV576821   EV581882   EV589870   GH744238
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7K3M5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033160    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033160 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033160 expression level Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4690) embryo 02-04hr  (6942) embryo 04-06hr  (8508) embryo 06-08hr  (8981) embryo 08-10hr  (8124) embryo 10-12hr  (6933) embryo 12-14hr  (3652) embryo 14-16hr  (3426) embryo 16-18hr  (2240) embryo 18-20hr  (1586) embryo 20-22hr  (2684) embryo 22-24hr  (2225) larva L1  (3923) larva L2  (2512) larva L3 12hr old  (1939) larva L3 puffstage 1-2  (1452) larva L3 puffstage 3-6  (2107) larva L3 puffstage 7-9  (2286) white prepupae new  (2140) white prepupae 12hr  (2617) white prepupae 24hr  (3040) pupae 2d postWPP  (2059) pupae 3d postWPP  (1263) pupae 4d postWPP  (1260) adult male 01day  (1460) adult male 05day  (2045) adult male 30day  (1989) adult female 01day  (3539) adult female 05day  (3763) adult female 30day  (3745) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4690) embryo 02-04hr  (6942) embryo 04-06hr  (8508) embryo 06-08hr  (8981) embryo 08-10hr  (8124) embryo 10-12hr  (6933) embryo 12-14hr  (3652) embryo 14-16hr  (3426) embryo 16-18hr  (2240) embryo 18-20hr  (1586) embryo 20-22hr  (2684) embryo 22-24hr  (2225) larva L1  (3923) larva L2  (2512) larva L3 12hr old  (1939) larva L3 puffstage 1-2  1452 larva L3 puffstage 3-6  (2107) larva L3 puffstage 7-9  (2286) white prepupae new  (2140) white prepupae 12hr  (2617) white prepupae 24hr  (3040) pupae 2d postWPP  (2059) pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day  1460 adult male 05day  (2045) adult male 30day  (1989) adult female 01day  (3539) adult female 05day  (3763) adult female 30day  (3745) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033160 expression level Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4690) embryo 02-04hr  (6942) embryo 04-06hr  (8508) embryo 06-08hr  (8981) embryo 08-10hr  (8124) embryo 10-12hr  (6933) embryo 12-14hr  (3652) embryo 14-16hr  (3426) embryo 16-18hr  (2240) embryo 18-20hr  (1586) embryo 20-22hr  (2684) embryo 22-24hr  (2225) larva L1  (3923) larva L2  (2512) larva L3 12hr old  (1939) larva L3 puffstage 1-2  (1452) larva L3 puffstage 3-6  (2107) larva L3 puffstage 7-9  (2286) white prepupae new  (2140) white prepupae 12hr  (2617) white prepupae 24hr  (3040) pupae 2d postWPP  (2059) pupae 3d postWPP  (1263) pupae 4d postWPP  (1260) adult male 01day  (1460) adult male 05day  (2045) adult male 30day  (1989) adult female 01day  (3539) adult female 05day  (3763) adult female 30day  (3745) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4690) embryo 02-04hr  (6942) embryo 04-06hr  (8508) embryo 06-08hr  (8981) embryo 08-10hr  (8124) embryo 10-12hr  (6933) embryo 12-14hr  (3652) embryo 14-16hr  (3426) embryo 16-18hr  2240 embryo 18-20hr  1586 embryo 20-22hr  (2684) embryo 22-24hr  2225 larva L1  (3923) larva L2  (2512) larva L3 12hr old  1939 larva L3 puffstage 1-2  1452 larva L3 puffstage 3-6  2107 larva L3 puffstage 7-9  2286 white prepupae new  2140 white prepupae 12hr  (2617) white prepupae 24hr  (3040) pupae 2d postWPP  2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day  1460 adult male 05day  2045 adult male 30day  1989 adult female 01day  (3539) adult female 05day  (3763) adult female 30day  (3745) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4690 embryo 02-04hr    6942 embryo 04-06hr    8508 embryo 06-08hr    8981 embryo 08-10hr    8124 embryo 10-12hr    6933 embryo 12-14hr    3652 embryo 14-16hr    3426 embryo 16-18hr    2240 embryo 18-20hr    1586 embryo 20-22hr    2684 embryo 22-24hr    2225 larva L1    3923 larva L2    2512 larva L3 12hr old    1939 larva L3 puffstage 1-2    1452 larva L3 puffstage 3-6    2107 larva L3 puffstage 7-9    2286 white prepupae new    2140 white prepupae 12hr    2617 white prepupae 24hr    3040 pupae 2d postWPP    2059 pupae 3d postWPP    1263 pupae 4d postWPP    1260 adult male 01day    1460 adult male 05day    2045 adult male 30day    1989 adult female 01day    3539 adult female 05day    3763 adult female 30day    3745 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033160    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033160 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033160 expression level Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033160 expression level Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.125 Larval Midgut    72.7 Larval Hindgut    148.4 Larval Malpighian Tubules    109 Larval Fat Body    104.2 Larval Salivary Gland    186.5 Larval Trachea    244.35 Larval Carcass    196.7 Adult Head    125.1 Adult Eye    106.225 Adult Brain    181.6 Adult Thoracic-Abdominal Ganglion    199.9 Adult Crop    164.9 Adult Midgut    86.1 Adult Hindgut    117.7 Adult Malpighian Tubules    98.5 Adult Fat Body    177.4 Adult Salivary Gland    132.4 Adult Heart    134.8 Adult VirginFemale Spermatheca    78.8 Adult InseminatedFemale Spermatheca    106.6 Adult Ovary    254.6 Adult Testis    138.6 Adult Male Accessory Gland    278.5 Adult Carcass    146.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    125.1   NA  Eye    106.225   NA  Brain    181.6   395.125  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    199.9   NA  Crop    164.9   72.7  Midgut    86.1   148.4  Hindgut    117.7   109  Malpighian Tubules    98.5   104.2  Fat Body    177.4   186.5  Salivary Gland    132.4   NA  Heart    134.8   244.35  Trachea    NA   NA  VirginFemale Spermatheca    78.8   NA  InseminatedFemale Spermatheca    106.6   NA  Ovary    254.6   NA  Testis    138.6   NA  Male Accessory Gland    278.5   196.7  Carcass    146.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033160 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11107-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG11107 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 CG11107GD7199 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG11107GD7199 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 CG11107GD7199 visible, with Scer\GAL4pnr-MD237 CG11107GD7199 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage, with Scer\GAL41407 CG11107GD7199 ganglion mother cell | larval stage, with Scer\GAL41407 CG11107GD7199 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG11107GD7199
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG11107 Class Mutagen Stocks Known lesion CG11107KG02727 P-element activity 2 -- CG111075-SZ-3362 1 -- CG11107CB-5084-3 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11107 Class Mutagen Stocks Known lesion CG11107GD7199 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7199} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG11107CB-5084-3 NA P{RS5}CG111075-SZ-3362 NA P{SUPor-P}CG11107KG02727 NA insertion of mobile activating element P{GSV1}C371C371 NA
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent helicase activity inferred from sequence or structural similarity with EMBL:AB001636 (FlyBase, 1992-) ATP-dependent RNA helicase activity inferred from sequence or structural similarity with Saccharomyces PRP43 (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) RNA helicase activity inferred from sequence or structural similarity (Liang and Biggin, 1998) inferred from sequence or structural similarity with NCBI:NP_011395 AND inferred from sequence or structural similarity with Saccharomyces PRP43 (Mount and Salz, 2000)
Biological Process
CV term Evidence References
nuclear mRNA splicing, via spliceosome inferred by curator from GO:0071011|GO:0071013 (Herold et al., 2009) inferred from sequence or structural similarity with NCBI:NP_011395 AND inferred from sequence or structural similarity with Saccharomyces PRP43 (Mount and Salz, 2000)
Cellular Component
CV term Evidence References
spliceosomal complex inferred from sequence or structural similarity with Saccharomyces PRP43 (Mount and Salz, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11107 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61535 DroID - A comprehensive database of gene and protein interactions. • FBgn0033160 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35654
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12707 Dere\GG23275 Dgri\GH21159 Dmoj\GI18757 Dper\GL11162 Dpse\GA10763 Dsec\GM20947 Dvir\GJ21780 Dwil\GK21317 Dyak\GE19122
Curated drosophilid orthologs	Dpse\GA10763
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004419-PA Aedes aegypti (mosquito) AGAP011149-PA Anopheles gambiae (mosquito) XP_392081.2 Apis mellifera (honey bee) XP_001945171.1 Acyrthosiphon pisum (pea aphid) At2g47250.1 Arabidopsis thaliana (wall cress) 13867 Batrachochytrium dendrobatidis (chytrid fungus) 59675 Branchiostoma floridae (lancelet) 97597 Branchiostoma floridae (lancelet) BGIBMGA009578-PA Bombyx mori (silk worm) ENSBTAP00000011714 Bos taurus (bovine) CAL0000153 Candida albicans (a form of yeast) CN08323 Caenorhabditis brenneri (small nematode) CBP31856 Caenorhabditis briggsae (nematode) CE01334 Caenorhabditis elegans (worm) ENSCAFP00000024285 Canis familiaris (dog) CAGL0F07139g Candida glabrata (haploid yeast) Chro.80471 Cryptosporidium hominis (obligate parasite) ENSCINP00000005405 Ciona intestinalis (sea squirt) JA18007 Caenorhabditis japonica (nematode) CMM048C Cyanidioschyzon merolae (red alga) cn06092 Cryptococcus neoformans (yeast-like fungus) cgd8_4100 Cryptosporidium parvum (protozoan parasite) CPIJ008192 Culex pipens (mosquito) ENSCPOP00000005824 Cavia porcellus (guinea pig) RP41260 Caenorhabditis remanei (nematode) 150705 Capitella spl (polychaete worm) DDB0233403 Dictyostelium discoideum (amoeba) DEHA2A09372g Debaryomyces Hansenii (yeast) 198525 Daphnia pulex (daphnia) ENSECAP00000020897 Equus caballus (horse) NP_414690.4 Escherichia coli K12 (bacteria) XP_656898 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023570 Gymnopilus aculeatus (mushroom) ENSGALP00000023214 Gallus gallus (chicken) 191960 Hypsipyla robusta (cedar shoot borer) ENSP00000336741 Homo sapiens (human) KLLA0B00561g Kluyveromyces lactis (yeast) 206726 Lottia gigantea (owl limpet) LmjF35.1200 Leishmania major (virus) ENSMODP00000000619 Monodelphis domestica (gray opossum) ENSMMUP00000012608 Macaca mulatta (rhesus monkey) ENSMUSP00000031061 Mus musculus (house mouse) 132292 Nematostella vectensis (starlet anemone) XP_001608279.1 Nasonia vitripennis (wasp) ENSOANP00000010667 Ornithorynchus anatinus (platypus) ENSORLP00000006067 Oryzias latipes (japanese killifish) LOC_Os03g19960.1 Oryza sativa (asian rice) 30318 Ostreococcus tauri (green alga) PFI0860c Plasmodium falciparum (protozoal parasite) PHUM000249-PA Pediculus humanus (human body louse) PP04341 Pristionchus pacificus (nematode) 176656 Physcomitrella patens (moss) 204131 Physcomitrella patens (moss) ENSPPYP00000016358 Pongo pygmaeus (orangutan) 71468 Phytophthora ramorum (sudden oak death pathogen) 108590 Phytophthora sojae (root rot pathogen) 799231 Populus trichocarpa (black cottonwood) ENSPTRP00000027472 Pan troglodytes (chimpanzee) PVX_099300 Plasmodium vivax (protozoal parasite) ENSRNOP00000005126 Rattus norvegicus (norway rat) YGL120C Saccharomyces cerevisiae (budding yeast) Smp_169650 Schistosoma mansoni (trematode parasite) SPBC16H5.10c Schizosaccharomyces pombe (fission yeast) XP_780422.1 Strongylocentrotus purpuratus (purple sea urchin) 61750 Trichoplax adhaerens (metazoa) TA16855 Theileria annulata (apicomplexan parasite) XP_966364.1 Tribolium castaneum (red flour beetle) Tc00.1047053503911.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000015334 Tetraodon nigroviridis (green spotted pufferfish) TP01_1019 Theileria parva (parasitic protozoan) 42282 Thalassiosira pseudonana (marine diatom) ENSTRUP00000035776 Takifugu rubripes (pufferfish Takifugu) 3760.m00252 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000004539 Xenopus tropicalis (frog) YALI0B15642g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13206 NV10474 LH21698 FBgn0236482 FBgn0223309 FBgn0208898 FBgn0182242 FBgn0175828 JGI_V11_198525 FBgn0070819 FBgn0148772 FBgn0141496 FBgn0128621 FBgn0115426 FBgn0089741 CPIJ008192 BGIBMGA009578 ACYPI007670 GB17778 AGAP011149 AAEL004419 PHUM227550 GLEAN_00481
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	12911 y1; P{SUPor-P}CG11107KG02727/CyO; ry506
Kyoto	123449 w1118; P{RS3}CG11107CB-5084-3 126018 w1118; P{RS5}CG111075-SZ-3362 111503 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}42D P{SUPor-P}CG11107KG02727 /CyO y+
VDRC	v44119 w1118; P{GD7199}v44119/CyO
Genomic Clones ( 1 )
	BACR26B18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 97 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM13272
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02460 AT08923 AT09859 AT18704 AT23592 AT29267 GM01950 GM07836 GM23829 GM24359 GM28281 LD03593 LD03891 LD05544 LD07088 LD08576 LD15670 LD16683 LD26149 LD30301 LD31551 LD34063 LD35213 LD36283 LD36635 LD36957 LD38781 LD45968 LD45969 LD47365 RE05060 RE06161 RE10186 RE11249 RE17032 RE17661 RE22903 RE22977 RE25259 RE27355 RE29360 RE29463 RE29849 RE30747 RE36477 RE42368 RE44137 RE52642 RE54706 RE60536 RE66289 RE74403 SD02838 SD03975 SD03987 SD09864 SD10088 SD10724 SD10947 SD12956 SD13327 SD15695 SD20237 SD20622
Other clones	40381 101370 105618 172597 214435.43 272931 274633 AI124258 CK01.66D.H9 CK01.170D.E10 Dmel_dig_013041_0645_2283 Dmel_dig_014735_0610_0828 Dmel_neb_013357_0337_2362 EC29252 EC37322 EC051042 EC052296 EC052557 EC053580 EC055129 EC055574 EC056661 EK053931 EK105149 EK153711 EK230818 EK256306 EK274118 EK299760 EK302349 EP19714 RP001000385
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033160 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35654
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG11107 anon-EST:Liang-1.18 (Ashburner, 2004.6.30)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136425 RefSeq (Proteins) • NP_610269 DDBJ / EMBL / GenBank • AA803479 AAF59269 AAL13713 AI124258 AI518952 AY058484 BH214601 Entrez Gene - A searchable database of RefSeq genes. • 35654 UniProtKB/TrEMBL • Q7K3M5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) Helicase-associated domain (IPR007502) Domain of unknown function DUF1605 (IPR011709) DEAD-like helicase (IPR014001) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61535 DroID - A comprehensive database of gene and protein interactions. • FBgn0033160 DRSC - Results from RNAi screens. • FBgn0033160 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033160 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11107-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033160 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35654 InParanoid A subset of ortholog calls from InParanoid. • AAEL004419-PA Aedes aegypti (mosquito) AGAP011149-PA Anopheles gambiae (mosquito) XP_392081.2 Apis mellifera (honey bee) XP_001945171.1 Acyrthosiphon pisum (pea aphid) At2g47250.1 Arabidopsis thaliana (wall cress) 13867 Batrachochytrium dendrobatidis (chytrid fungus) 59675 Branchiostoma floridae (lancelet) 97597 Branchiostoma floridae (lancelet) BGIBMGA009578-PA Bombyx mori (silk worm) ENSBTAP00000011714 Bos taurus (bovine) CAL0000153 Candida albicans (a form of yeast) CN08323 Caenorhabditis brenneri (small nematode) CBP31856 Caenorhabditis briggsae (nematode) CE01334 Caenorhabditis elegans (worm) ENSCAFP00000024285 Canis familiaris (dog) CAGL0F07139g Candida glabrata (haploid yeast) Chro.80471 Cryptosporidium hominis (obligate parasite) ENSCINP00000005405 Ciona intestinalis (sea squirt) JA18007 Caenorhabditis japonica (nematode) CMM048C Cyanidioschyzon merolae (red alga) cn06092 Cryptococcus neoformans (yeast-like fungus) cgd8_4100 Cryptosporidium parvum (protozoan parasite) CPIJ008192 Culex pipens (mosquito) ENSCPOP00000005824 Cavia porcellus (guinea pig) RP41260 Caenorhabditis remanei (nematode) 150705 Capitella spl (polychaete worm) DDB0233403 Dictyostelium discoideum (amoeba) DEHA2A09372g Debaryomyces Hansenii (yeast) 198525 Daphnia pulex (daphnia) ENSECAP00000020897 Equus caballus (horse) NP_414690.4 Escherichia coli K12 (bacteria) XP_656898 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023570 Gymnopilus aculeatus (mushroom) ENSGALP00000023214 Gallus gallus (chicken) 191960 Hypsipyla robusta (cedar shoot borer) ENSP00000336741 Homo sapiens (human) KLLA0B00561g Kluyveromyces lactis (yeast) 206726 Lottia gigantea (owl limpet) LmjF35.1200 Leishmania major (virus) ENSMODP00000000619 Monodelphis domestica (gray opossum) ENSMMUP00000012608 Macaca mulatta (rhesus monkey) ENSMUSP00000031061 Mus musculus (house mouse) 132292 Nematostella vectensis (starlet anemone) XP_001608279.1 Nasonia vitripennis (wasp) ENSOANP00000010667 Ornithorynchus anatinus (platypus) ENSORLP00000006067 Oryzias latipes (japanese killifish) LOC_Os03g19960.1 Oryza sativa (asian rice) 30318 Ostreococcus tauri (green alga) PFI0860c Plasmodium falciparum (protozoal parasite) PHUM000249-PA Pediculus humanus (human body louse) PP04341 Pristionchus pacificus (nematode) 176656 Physcomitrella patens (moss) 204131 Physcomitrella patens (moss) ENSPPYP00000016358 Pongo pygmaeus (orangutan) 71468 Phytophthora ramorum (sudden oak death pathogen) 108590 Phytophthora sojae (root rot pathogen) 799231 Populus trichocarpa (black cottonwood) ENSPTRP00000027472 Pan troglodytes (chimpanzee) PVX_099300 Plasmodium vivax (protozoal parasite) ENSRNOP00000005126 Rattus norvegicus (norway rat) YGL120C Saccharomyces cerevisiae (budding yeast) Smp_169650 Schistosoma mansoni (trematode parasite) SPBC16H5.10c Schizosaccharomyces pombe (fission yeast) XP_780422.1 Strongylocentrotus purpuratus (purple sea urchin) 61750 Trichoplax adhaerens (metazoa) TA16855 Theileria annulata (apicomplexan parasite) XP_966364.1 Tribolium castaneum (red flour beetle) Tc00.1047053503911.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000015334 Tetraodon nigroviridis (green spotted pufferfish) TP01_1019 Theileria parva (parasitic protozoan) 42282 Thalassiosira pseudonana (marine diatom) ENSTRUP00000035776 Takifugu rubripes (pufferfish Takifugu) 3760.m00252 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000004539 Xenopus tropicalis (frog) YALI0B15642g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35654 modMine - Data generated by the modENCODE project. • FBgn0033160 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13206 NV10474 LH21698 FBgn0236482 FBgn0223309 FBgn0208898 FBgn0182242 FBgn0175828 JGI_V11_198525 FBgn0070819 FBgn0148772 FBgn0141496 FBgn0128621 FBgn0115426 FBgn0089741 CPIJ008192 BGIBMGA009578 ACYPI007670 GB17778 AGAP011149 AAEL004419 PHUM227550 GLEAN_00481
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	anon-EST:Liang-1.18   cg11107 (Lasko, 2000) CG11107 (Molnar et al., 2006, Herold et al., 2009, Liebl and Featherstone, 2005, Neumüller et al., 2011) clone 1.18 (Liang and Biggin, 1998)
Name Synonym
Secondary FlyBase IDs
	FBgn0026004
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 2 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 )
Recent research papers ( 1 )
	Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Show all research papers ...