• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG12822

General Information
Symbol	Dmel\CG12822	Species	D. melanogaster
Name		Annotation symbol	CG12822
Feature type	protein_coding_gene	FlyBase ID	FBgn0033229
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43E18-43E18	Sequence location	2R:3,719,676..3,721,346 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12822 (FBgn0033229). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Uncharacterised domain UPF0066; Uncharacterised domain UPF0066, YaeB-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1641689_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG12822 expression signal. See the GBrowse view of CG12822 to determine the overlapping gene(s). Gene sequence location is 2R:3719676..3721346.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43E18-43E18   Limits computationally determined from genome sequence between P{EP}CanB2EP774 and P{lacW}lin19k01207&P{lacW}rnh1k07624
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12822 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51 Gene model reviewed during 5.46 Shares 5' UTR with downstream gene.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12822-RA FBtr0088841  NM_136483   1522   412 CG12822-RB FBtr0088842  NM_206052   1468   394
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12822-PA   FBpp0087917   46.1   412   6.24     NP_610327   AAF59182 CG12822-PB   FBpp0087918   44.0   394   6.35     NP_995774   AAS64896
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised domain UPF0066, YaeB-like domain (IPR023370) Uncharacterised domain UPF0066 (IPR001378)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392342   AE013599 AAF59182   AE013599 AAS64896   AI389934   AI404647   AI513719   AI533083   AY122124 AAM52636   BF500779   BI171679   BI171742   BI171945   BI228427   BI234668   BI365654   BI365708   BI375349   BI563440   BI568599   BI574974   BI578245   BI583937   BI584197   BI585171   BI586540   BI587228   BI610412   BI617996   BI619316   BI623052   BI625081   BI626731   BI626742   BI632529   BI641452   BT001584 AAN71339   BT023823   CK135506   CK135570   CK660408   CO156978   CO177234   CO315940   CO331539   CZ484517   CZ484526   EC215271   EL873673   EL873774   EL878705   EL878896   EL882794   EL882795   EL882986   EL882987   EL883058   EL883540   EV580584   EV598997   FD585801   FD585812   FD585936   FD585966   GH739409   GH739747   GH740655   GH743091   GH744856   GH745717   GH745934   GH747079   GH761719   GH761939   GH762046   GH762277   GH762888   GH763175   GH763360   GH764617   GH765003   GH766186   GH768784   GH769307
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MR50 A1Z759
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion  516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion  516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    197.95 Larval Midgut    77.5 Larval Hindgut    77.4 Larval Malpighian Tubules    58.3 Larval Fat Body    50.2 Larval Salivary Gland    81.9 Larval Trachea    141.15 Larval Carcass    82.375 Adult Head    182.2 Adult Eye    179.15 Adult Brain    494.5 Adult Thoracic-Abdominal Ganglion    516.6 Adult Crop    152.8 Adult Midgut    96.6 Adult Hindgut    128.7 Adult Malpighian Tubules    107.2 Adult Fat Body    122.8 Adult Salivary Gland    219 Adult Heart    110.3 Adult VirginFemale Spermatheca    142.9 Adult InseminatedFemale Spermatheca    148.5 Adult Ovary    112.9 Adult Testis    32.7 Adult Male Accessory Gland    151.3 Adult Carcass    159.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    182.2   NA  Eye    179.15   NA  Brain    494.5   197.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    516.6   NA  Crop    152.8   77.5  Midgut    96.6   77.4  Hindgut    128.7   58.3  Malpighian Tubules    107.2   50.2  Fat Body    122.8   81.9  Salivary Gland    219   NA  Heart    110.3   141.15  Trachea    NA   NA  VirginFemale Spermatheca    142.9   NA  InseminatedFemale Spermatheca    148.5   NA  Ovary    112.9   NA  Testis    32.7   NA  Male Accessory Gland    151.3   82.375  Carcass    159.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female  26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male  (35) head, mated 4-day male  (39) head, mated 20-day male  (59) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female  (29) ovary, mated 4-day female  26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female  26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male  (35) head, mated 4-day male  (39) head, mated 20-day male  (59) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female  29 ovary, mated 4-day female  26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    22 central nervous system, pupae P8    20 head, virgin 1-day female    22 head, virgin 4-day female    22 head, virgin 20-day female    26 head, mated 1-day female    20 head, mated 4-day female    23 head, mated 20-day female    19 head, mated 1-day male    35 head, mated 4-day male    39 head, mated 20-day male    59 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    16 digestive system, 4-day adult    12 digestive system, 20-day adult    17 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    17 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    14 ovary, virgin 4-day female    29 ovary, mated 4-day female    26 testis, mated 4-day male    17 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (30) embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr  26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP  (43) adult male 01day    19 adult male 05day  (27) adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day  (28) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr  26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP  (43) adult male 01day    19 adult male 05day  27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day  28 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    16 embryo 04-06hr    17 embryo 06-08hr    21 embryo 08-10hr    23 embryo 10-12hr    26 embryo 12-14hr    15 embryo 14-16hr    15 embryo 16-18hr    14 embryo 18-20hr    13 embryo 20-22hr    12 embryo 22-24hr    12 larva L1    19 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    23 white prepupae 24hr    24 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    43 adult male 01day    19 adult male 05day    27 adult male 30day    22 adult female 01day    23 adult female 05day    25 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (93) Schneider line 2 Sg4  (67) embryonic 1182-4H  (47) embryonic GM2  (49) embryonic Kc167  (50) embryonic S1  (69) embryonic S3  (55) leg disc CME L1  (42) wing disc CME-W2  (40) wing disc ML-DmD8  (37) wing disc ML-DmD9  (48) wing disc ML-DmD16-c3  (35) wing disc ML-DmD21  (66) wing disc ML-DmD32  (55) haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11  (30) antennal disc ML-DmD20-c5  (48) mixed discs ML-DmD4-c1  (31) CNS ML-DmBG1-c1  (31) CNS ML-DmBG2-c2  (69) tumorous blood cells mbn2  (42) ovary fGS/OSS  (46) ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (93) Schneider line 2 Sg4  (67) embryonic 1182-4H  (47) embryonic GM2  (49) embryonic Kc167  (50) embryonic S1  (69) embryonic S3  (55) leg disc CME L1  (42) wing disc CME-W2  (40) wing disc ML-DmD8  (37) wing disc ML-DmD9  (48) wing disc ML-DmD16-c3  (35) wing disc ML-DmD21  (66) wing disc ML-DmD32  (55) haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11  30 antennal disc ML-DmD20-c5  (48) mixed discs ML-DmD4-c1  31 CNS ML-DmBG1-c1  31 CNS ML-DmBG2-c2  (69) tumorous blood cells mbn2  (42) ovary fGS/OSS  (46) ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    67 embryonic 1182-4H    47 embryonic GM2    49 embryonic Kc167    50 embryonic S1    69 embryonic S3    55 leg disc CME L1    42 wing disc CME-W2    40 wing disc ML-DmD8    37 wing disc ML-DmD9    48 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    66 wing disc ML-DmD32    55 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    30 antennal disc ML-DmD20-c5    48 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    31 CNS ML-DmBG2-c2    69 tumorous blood cells mbn2    42 ovary fGS/OSS    46 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult  (34) Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  (43) Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (32) Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  (47) Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult  (34) Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3  (43) Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  (47) Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    34 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    43 Ethanol 5% 3 hrs, larvae L3    19 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    47 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_21 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033229 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12822-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG12822GD7839 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG12822 Class Mutagen Stocks Known lesion CG12822f02022 piggyBac transposase 2 -- CG12822f02030 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12822 Class Mutagen Stocks Known lesion CG12822GD7839 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG12822NIG.12822R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7839} NA P{NIG.12822R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG00610 NA PBac{WH}CG12822f02022 NA PBac{WH}CG12822f02030 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12822 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0033229
Orthologs
OrthoDB Orthologs (35) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6H46PR Dipteran inclusive ortholog search EOG6PZJGC Insect inclusive ortholog search EOG6MCVVC Arthropod inclusive ortholog search EOG6V41PR Metazoa inclusive ortholog search EOG6FFRTS
Orthologs in Drosophila Species (EOG6H46PR)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG12822     Drosophila simulans   Dsim\GD10513 Y   Drosophila sechellia   Dsec\GM20986 Y   Drosophila erecta   Dere\GG23308 Y   Drosophila yakuba   Dyak\GE19153 Y   Drosophila ananassae   Dana\GF13638 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11834 Y   Drosophila persimilis   Dper\GL11692 Y   Drosophila willistoni   Dwil\GK21968 Y   Drosophila virilis   Dvir\GJ17719 Y   Drosophila mojavensis   Dmoj\GI19783 Y   Drosophila grimshawi   Dgri\GH21293 Y
Orthologs in non-Drosophila Dipterans (EOG6PZJGC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007313   Anopheles gambiae Malaria mosquito  Agam\AGAP012444   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ000135
Orthologs in non-Dipteran Insects (EOG6MCVVC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB53196 Y Apis mellifera Western honey bee  Amel\GB46988 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG030688 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17512 Y Atta cephalotes Leafcutter ant  Acep\ACEP12937 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO22912 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14354 Y Linepithema humile Argentine ant  Lhum\LH19178 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18344 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI003470 Y Bombyx mori Silkmoth  Bmor\BGIBMGA013897 Y Pediculus humanus Human body louse  Phum\PHUM370960 Y Tribolium castaneum Red flour beetle  Tcas\TC030545 Y
Orthologs in non-Insect Arthropods (EOG6V41PR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW014570 Y
Orthologs in non-Arthropod Metazoa (EOG6FFRTS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024998gn   Danio rerio Zebrafish  Drer\zgc:123172   Xenopus tropicalis Western clawed frog  Xtro\c9orf156   Mus musculus House mouse  Mmus\Nap1   Rattus norvegicus Norway rat  Rnor\RGD1305420   Homo sapiens Human  Hsap\C9orf156
Human Orthologs (1)
Gene OMIM HGNC Hsap\C9orf156
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10513 Drosophila sechellia Dsec\GM20986 Drosophila erecta Dere\GG23308 Drosophila yakuba Dyak\GE19153 Drosophila ananassae Dana\GF13638 Drosophila pseudoobscura pseudoobscura Dpse\GA11834 Drosophila persimilis Dper\GL11692 Drosophila willistoni Dwil\GK21968 Drosophila virilis Dvir\GJ17719 Drosophila mojavensis Dmoj\GI19783 Drosophila grimshawi Dgri\GH21293
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	18503 w1118; PBac{WH}CG12822f02022/CyO
Harvard	- PBac{WH}CG12822f02022 - PBac{WH}CG12822f02030
VDRC	v32031 w1118 P{GD7839}v32031 v32029 w1118; P{GD7839}v32029
Genomic Clones ( 1 )
	BACR04B09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 72 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH21247 RE25969 RH23185
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT15810 GH24434 GH26775 LD11186 LP18956 RE13504 RE13575 RE13847 RE30411 RE51039 RE51075 RE63131 RE72089 RH15883 RH22661 RH24647 RH26602 RH27530 RH27738 RH34074 RH40221 RH48505 RH64914 RH67763 RH67784 SD04779 SD24793 SD26332
Other clones	160457 Dmel_dig_018968_0649_3345 Dmel_neb_012376_0927_2165 EK052952 EK263156 EK300408 EN09705 IP08552 IP08752 IP12471 IP12671 IP12771 IP13201 IP13761 IP13861 RH50328 RH55120 RM02069 RM02169 RM02369 RM02469 RP001011510 RP001014492 RP001016374 RP001020886 RP001024186 RP001024384 RP001025620 RP001025986 RP001027051 RP001031126 RP001034901 RP001037140 RP001038843 RP001040217 RP001041090 RP001041586 RP001046596 RP001051650 RP001052831 RP001055516
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033229 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35737
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	CG18853 appears to be a chimeric gene, with the 5' part of the gene derived from CG12822 and the 3' part of the gene derived from phr. (Rogers and Hartl, 2012) "CG18853" is a putative chimeric gene derived from the "CG12822" and "phr" genes (where coding sequences of the two parental genes contribute to the coding sequence of the chimeric gene). (Rogers et al., 2009)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136483 NM_206052 RefSeq (Proteins) • NP_610327 NP_995774 DDBJ / EMBL / GenBank • AAF59182 AAM52636 AAN71339 AAS64896 AI389934 AY122124 BI228427 BI584197 BI619316 BI623052 BT001584 CZ484517 CZ484526 Entrez Gene - A searchable database of RefSeq genes. • 35737 UniProtKB/TrEMBL • A1Z759 Q8MR50
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised domain UPF0066, YaeB-like domain (IPR023370) Uncharacterised domain UPF0066 (IPR001378)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0033229 DRSC - Results from RNAi screens. • FBgn0033229 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033229 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12822-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033229 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35737 modMine - Data generated by the modENCODE project. • FBgn0033229
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG12822 (Rogers and Hartl, 2012, Zhan et al., 2011, Japanese National Institute of Genetics, 2012.5.21) CG12822-PA (Rogers et al., 2009)
Name Synonym
Secondary FlyBase IDs
References ( 16 )
Research paper	Rogers and Hartl, 2012, Mol. Biol. Evol. 29(2): 517--529 Chimeric Genes as a Source of Rapid Evolution in Drosophila melanogaster. [FBrf0217452] Zhan et al., 2011, Gene 470(1-2): 1--6 Evolution of alternative splicing in newly evolved genes of Drosophila. [FBrf0212278] Rogers et al., 2009, Genetics 181(1): 313--322 Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. [FBrf0207085]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Torroja, 2003.10.29, FlyBase error report for CG18853 on Wed Oct 29 08:59:30 2003. FlyBase error report for CG18853 on Wed Oct 29 08:59:30 2003. [FBrf0173220] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] Levis, 2001.5.22, CG12822 and CG18853 - one or two genes? CG12822 and CG18853 - one or two genes? [FBrf0138594] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]