dKDM4A, Histone demethylase 4A
histone demethylase - regulates H3K36me3 levels - regulates heterochromatin organization and function - Jun recruits the HP1a/KDM4A complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation - along with Kdm4B, Kdm4A is essential for mediating ecdysteroid hormone signaling during larval development
Gene model reviewed during 5.41
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Kdm4A using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Kdm4A in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Kdm4A CG15835