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Gene Dmel\CG8712

General Information
Symbol	Dmel\CG8712	Species	D. melanogaster
Name		Annotation symbol	CG8712
Feature type	protein_coding_gene	FlyBase ID	FBgn0033258
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	44A4-44A4	Sequence location	2R:3,984,297..3,985,989 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8712 (FBgn0033258). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1640084_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG8712. Gene sequence location is 2R:3984297..3985989.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 44A4-44A4   Limits computationally determined from genome sequence between P{lacW}Vps28k16503 and P{EP}kermitEP493
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8712 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8712-RA FBtr0088822  NM_136506   1489   417 CG8712-RB FBtr0088823  NM_165587   1693   417
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8712-PA   FBpp0087898   46.5   417   10.49     NP_610350   AAF59137 CG8712-PB   FBpp0087899   46.5   417   10.49     NP_724644   AAM68849
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696206   AE013599 AAF59137   AE013599 AAM68849   BF488639   BF498068   BF501315   BF504704   BF506764   BT003806   CL527966   CO329495   CZ478047   CZ478048   CZ479301   EC250673   GH943852   GH944196   GH949722   GH952312   GH958021   GH961259   GH961662   GH964081   GH973344   GH984322
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7JQU5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis  (710) Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis  710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    70.275 Larval Midgut    13.5 Larval Hindgut    16.2 Larval Malpighian Tubules    20.2 Larval Fat Body    96.3 Larval Salivary Gland    7.7 Larval Trachea    30.525 Larval Carcass    13 Adult Head    19.6 Adult Eye    19.175 Adult Brain    42.4 Adult Thoracic-Abdominal Ganglion    30.3 Adult Crop    11.3 Adult Midgut    9.1 Adult Hindgut    12.7 Adult Malpighian Tubules    14.8 Adult Fat Body    16.6 Adult Salivary Gland    3 Adult Heart    16.7 Adult VirginFemale Spermatheca    11.5 Adult InseminatedFemale Spermatheca    12.3 Adult Ovary    128.2 Adult Testis    710 Adult Male Accessory Gland    44.5 Adult Carcass    15.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    19.6   NA  Eye    19.175   NA  Brain    42.4   70.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    30.3   NA  Crop    no informative data   no informative data  Midgut    9.1   16.2  Hindgut    12.7   20.2  Malpighian Tubules    no informative data   96.3  Fat Body    no informative data   7.7  Salivary Gland    3   NA  Heart    16.7   30.525  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    128.2   NA  Testis    710   NA  Male Accessory Gland    44.5   no informative data  Carcass    15.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (45) central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female  (28) ovary, mated 4-day female    24 testis, mated 4-day male  (75) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (45) central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female  28 ovary, mated 4-day female    24 testis, mated 4-day male  (75) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    45 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    9 fat body, pupae P8    16 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    75 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day  (28) adult male 05day  (37) adult male 30day  (33) adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day  28 adult male 05day  (37) adult male 30day  (33) adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    25 embryo 02-04hr    6 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    8 embryo 10-12hr    5 embryo 12-14hr    4 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    2 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    23 pupae 3d postWPP    20 pupae 4d postWPP    15 adult male 01day    28 adult male 05day    37 adult male 30day    33 adult female 01day    5 adult female 05day    15 adult female 30day    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    4 embryonic 1182-4H    3 embryonic GM2    4 embryonic Kc167    2 embryonic S1    5 embryonic S3    3 leg disc CME L1    4 wing disc CME-W2    6 wing disc ML-DmD8    4 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    2 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    4 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    3 ovary fGS/OSS    4 ovary OSC    3 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    19 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    21 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	BDGP expression data • AT09333 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033258 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8712-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG8712EY07021 viable, with Scer\GAL4pnr-MD237 CG8712GD14007 Sterility Allele fertile CG8712EY07021 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG8712 Class Mutagen Stocks Known lesion CG8712e00152 piggyBac transposase 1 -- CG8712EY07021 P-element activity 1 -- CG8712e01489 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8712 Class Mutagen Stocks Known lesion CG8712GD14007 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6056 (Ryder, 2004.4.26) Df(2R)Exel7094 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14007} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG8712EY07021 NA miscellaneous insertions PBac{RB}CG8712e00152 NA PBac{RB}CG8712e01489 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8712 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61635 DroID - A comprehensive database of gene and protein interactions. • FBgn0033258
Orthologs
OrthoDB Orthologs (13) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NW05S Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6NW05S)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG8712     Drosophila simulans   Dsim\GD10192 Y   Drosophila sechellia   Dsec\GM20726 Y   Drosophila erecta   Dere\GG10679 Y   Drosophila yakuba   Dyak\GE23334 Y   Drosophila ananassae   Dana\GF11214 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA24810 Y   Drosophila persimilis   Dper\GL17384 Y   Drosophila willistoni   Dwil\GK19221     Drosophila willistoni   Dwil\GK15291 Y   Drosophila virilis   Dvir\GJ20229 Y   Drosophila mojavensis   Dmoj\GI20165 Y   Drosophila grimshawi   Dgri\GH19990 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10192 Drosophila sechellia Dsec\GM20726 Drosophila erecta Dere\GG10679 Drosophila yakuba Dyak\GE23334 Drosophila ananassae Dana\GF11214 Drosophila pseudoobscura pseudoobscura Dpse\GA24810 Drosophila persimilis Dper\GL17384 Drosophila willistoni Dwil\GK15291 Drosophila virilis Dvir\GJ20229 Drosophila mojavensis Dmoj\GI20165 Drosophila grimshawi Dgri\GH19990
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	16778 y1 w67c23; P{EPgy2}CG8712EY07021
Harvard	- PBac{RB}CG8712e00152
VDRC	v46108 w1118; P{GD14007}v46108 v46109 w1118; P{GD14007}v46109
Genomic Clones ( 2 )
	BACR09N11 BACR38O04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 18 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT09333
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT06380 AT12427 AT16604 AT24125 GM05273
Other clones	190720 EK292956 RP004045267 RP004145980 RP004181602 RP004200039 RP004242951 RP004245953 RP004383127 RP004507032 RP004532798 RP004536979
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033258 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35778
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136506 NM_165587 RefSeq (Proteins) • NP_610350 NP_724644 DDBJ / EMBL / GenBank • AAF59137 AAM68849 BF506764 CL527966 CZ478047 CZ478048 CZ479301 Entrez Gene - A searchable database of RefSeq genes. • 35778 UniProtKB/TrEMBL • Q7JQU5
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • AT09333
Linkouts
	BioGRID - A database of protein and genetic interactions • 61635 DroID - A comprehensive database of gene and protein interactions. • FBgn0033258 DRSC - Results from RNAi screens. • FBgn0033258 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033258 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8712-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033258 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35778 modMine - Data generated by the modENCODE project. • FBgn0033258
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8712 (Blanco et al., 2010, Geng and MacDonald, 2007)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Geng and MacDonald, 2007, Fly 1(5): 259--267 Identification of genes that influence gurken expression. [FBrf0205043]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]