dCirl, latrophilin
G-protein coupled receptor - involved in the perception of tactile, proprioceptive, and auditory stimuli through chordotonal neurons of the PNS - sensitizes these neurons for the detection of mechanical stimulation by amplifying their input-output function
Please see the JBrowse view of Dmel\Cirl for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.43
Gene model reviewed during 5.49
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembrane moiety.
Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cirl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Cirl in GBrowse 22-59
2-57.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Cirl CG8639
Source for merge of: Cirl BcDNA:GH07331
Source for merge of: Cirl anon-WO0170980.7 anon-WO0170980.8
Source for merge of Cirl BcDNA:GH07331 was a shared cDNA ( date:020730 ).
Source for merge of Cirl anon-WO0170980.7 anon-WO0170980.8 was sequence comparison ( date:051113 ).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.