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Gene Dmel\CG8235

General Information
Symbol	Dmel\CG8235	Species	D. melanogaster
Name		Annotation symbol	CG8235
Feature type	protein_coding_gene	FlyBase ID	FBgn0033351
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	44F8-44F8	Sequence location	2R:4,814,519..4,815,610 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8235 (FBgn0033351). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: tRNA binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nucleic acid-binding, OB-fold; tRNA-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626469_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8235. Gene sequence location is 2R:4814519..4815610.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 44F8-44F8   Limits computationally determined from genome sequence between P{lacW}Dmnk16109&P{lacW}Gγ1k08017 and P{lacW}babok16912
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8235 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency junction(s) not annotated. Gene model reviewed during 5.44 Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8235-RA FBtr0088676  NM_136582   1036   323
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8235-PA   FBpp0087757   34.4   323   9.28     NP_610426   AAF59019
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • tRNA-binding domain (IPR002547) Nucleic acid-binding, OB-fold (IPR012340)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF59019   AI517252   AY071480 AAL49102   BI171354   BI352005   BI352168   BI353007   BI369016   EL880822   EL880823   EV579820   EV591864
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A1Z7K8 Q8SYK9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic foregut   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval salivary gland   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland  (561) Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland  561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    289.1 Larval Midgut    159.9 Larval Hindgut    246.2 Larval Malpighian Tubules    229.3 Larval Fat Body    213 Larval Salivary Gland    561 Larval Trachea    468.55 Larval Carcass    240.85 Adult Head    182.3 Adult Eye    223.3 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    135.4 Adult Crop    234.9 Adult Midgut    166.6 Adult Hindgut    153.3 Adult Malpighian Tubules    318.3 Adult Fat Body    168 Adult Salivary Gland    278.1 Adult Heart    215.75 Adult VirginFemale Spermatheca    228.9 Adult InseminatedFemale Spermatheca    282.7 Adult Ovary    453.3 Adult Testis    81.5 Adult Male Accessory Gland    268 Adult Carcass    181.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    182.3   NA  Eye    223.3   NA  Brain    92.1   289.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    135.4   NA  Crop    234.9   159.9  Midgut    166.6   246.2  Hindgut    153.3   229.3  Malpighian Tubules    318.3   213  Fat Body    168   561  Salivary Gland    278.1   NA  Heart    215.75   468.55  Trachea    NA   NA  VirginFemale Spermatheca    228.9   NA  InseminatedFemale Spermatheca    282.7   NA  Ovary    453.3   NA  Testis    81.5   NA  Male Accessory Gland    268   240.85  Carcass    181.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (46) central nervous system, larvae L3  (33) central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering  (30) carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  (64) ovary, mated 4-day female  (55) testis, mated 4-day male  (35) accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (46) central nervous system, larvae L3  (33) central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering  30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  (64) ovary, mated 4-day female  (55) testis, mated 4-day male  (35) accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    33 central nervous system, pupae P8    11 head, virgin 1-day female    15 head, virgin 4-day female    12 head, virgin 20-day female    12 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    13 head, mated 1-day male    9 head, mated 4-day male    10 head, mated 20-day male    12 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    17 digestive system, 4-day adult    19 digestive system, 20-day adult    17 fat body, larvae L3 wandering    13 fat body, white prepupae    17 fat body, pupae P8    22 carcass, larvae L3 wandering    30 carcass, 1-day adult    12 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    64 ovary, mated 4-day female    55 testis, mated 4-day male    35 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (48) embryo 02-04hr    12 embryo 04-06hr  26 embryo 06-08hr  (29) embryo 08-10hr    23 embryo 10-12hr  (30) embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1  (40) larva L2  (45) larva L3 12hr old  (38) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day  (33) adult female 05day  (49) adult female 30day  (54) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (48) embryo 02-04hr    12 embryo 04-06hr  26 embryo 06-08hr  29 embryo 08-10hr    23 embryo 10-12hr  30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1  (40) larva L2  (45) larva L3 12hr old  (38) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day  (33) adult female 05day  (49) adult female 30day  (54) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    48 embryo 02-04hr    12 embryo 04-06hr    26 embryo 06-08hr    29 embryo 08-10hr    23 embryo 10-12hr    30 embryo 12-14hr    19 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    16 embryo 20-22hr    19 embryo 22-24hr    14 larva L1    40 larva L2    45 larva L3 12hr old    38 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    23 white prepupae new    21 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    19 pupae 3d postWPP    15 pupae 4d postWPP    12 adult male 01day    14 adult male 05day    15 adult male 30day    12 adult female 01day    33 adult female 05day    49 adult female 30day    54 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (54) Schneider line 2 Sg4  (67) embryonic 1182-4H  (43) embryonic GM2  (42) embryonic Kc167    21 embryonic S1  (92) embryonic S3  (60) leg disc CME L1  (64) wing disc CME-W2  (40) wing disc ML-DmD8  (40) wing disc ML-DmD9  (47) wing disc ML-DmD16-c3  (48) wing disc ML-DmD21  (63) wing disc ML-DmD32  (78) haltere disc ML-DmD17-c3  (49) eye-antennal disc ML-DmD11  (60) antennal disc ML-DmD20-c5  (87) mixed discs ML-DmD4-c1  (39) CNS ML-DmBG1-c1  (64) CNS ML-DmBG2-c2  (38) tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (54) Schneider line 2 Sg4  (67) embryonic 1182-4H  (43) embryonic GM2  (42) embryonic Kc167    21 embryonic S1  (92) embryonic S3  (60) leg disc CME L1  (64) wing disc CME-W2  (40) wing disc ML-DmD8  (40) wing disc ML-DmD9  (47) wing disc ML-DmD16-c3  (48) wing disc ML-DmD21  (63) wing disc ML-DmD32  (78) haltere disc ML-DmD17-c3  (49) eye-antennal disc ML-DmD11  (60) antennal disc ML-DmD20-c5  (87) mixed discs ML-DmD4-c1  (39) CNS ML-DmBG1-c1  (64) CNS ML-DmBG2-c2  (38) tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    54 Schneider line 2 Sg4    67 embryonic 1182-4H    43 embryonic GM2    42 embryonic Kc167    21 embryonic S1    92 embryonic S3    60 leg disc CME L1    64 wing disc CME-W2    40 wing disc ML-DmD8    40 wing disc ML-DmD9    47 wing disc ML-DmD16-c3    48 wing disc ML-DmD21    63 wing disc ML-DmD32    78 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    60 antennal disc ML-DmD20-c5    87 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    64 CNS ML-DmBG2-c2    38 tumorous blood cells mbn2    24 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult  (30) Cadmium 50 mM 6 hrs, larvae L3  (35) Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult  (32) Cadmium 100 mM 48 hrs, 4-day adult  (41) Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3  (45) Ethanol 5% 3 hrs, larvae L3  26 Ethanol 10% 3 hrs, larvae L3  (31) Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (40) Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  (33) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3  (34) Rotenone 8 μg 12 hrs, larvae L3  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult  30 Cadmium 50 mM 6 hrs, larvae L3  (35) Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult  32 Cadmium 100 mM 48 hrs, 4-day adult  (41) Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3  (45) Ethanol 5% 3 hrs, larvae L3  26 Ethanol 10% 3 hrs, larvae L3  31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (40) Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  (33) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3  (34) Rotenone 8 μg 12 hrs, larvae L3  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    20 cold shock, 4-day adult    12 heat shock, 4-day adult    30 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    19 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    45 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    40 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    33 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    34 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • RE55091 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033351 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8235-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8235 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG8235 Class Mutagen Stocks Known lesion CG8235CB-5088-3 1 -- CG8235UM-8162-3 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8235 Class Mutagen Stocks Known lesion CG8235GD13853 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel8048 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13853} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG8235CB-5088-3 NA P{RS3}CG8235UM-8162-3 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
tRNA binding inferred from electronic annotation with InterPro:IPR002547 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
aminoacyl-tRNA synthetase multienzyme complex inferred from sequence or structural similarity with EMBL:AF021800 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG8235 - Aats-arg experimental knowledge based (Guruharsha et al., 2011) CG8235 - Aats-asp experimental knowledge based (Guruharsha et al., 2011) CG8235 - Aats-gln experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG8235 - Aats-glupro experimental knowledge based (Guruharsha et al., 2011) CG8235 - Aats-ile experimental knowledge based (Guruharsha et al., 2011) CG8235 - Aats-lys anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8235 - CG12304 experimental knowledge based (Guruharsha et al., 2011) CG8235 - CG15100 experimental knowledge based (Guruharsha et al., 2011) CG8235 - PHGPx anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8235 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61730 DroID - A comprehensive database of gene and protein interactions. • FBgn0033351 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35892
Orthologs
OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6XH0KC Dipteran inclusive ortholog search EOG6R50BT Insect inclusive ortholog search EOG62RC4N Arthropod inclusive ortholog search EOG6GTHW7 Metazoa inclusive ortholog search EOG6ND07H
Orthologs in Drosophila Species (EOG6XH0KC)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG8235     Drosophila simulans   Dsim\GD15265 Y   Drosophila sechellia   Dsec\GM20651 Y   Drosophila erecta   Dere\GG10606 Y   Drosophila yakuba   Dyak\GE22699 Y   Drosophila ananassae   Dana\GF12729 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20918 Y   Drosophila persimilis   Dper\GL10404 Y   Drosophila willistoni   Dwil\GK10745 Y   Drosophila virilis   Dvir\GJ21051 Y   Drosophila mojavensis   Dmoj\GI20611 Y   Drosophila grimshawi   Dgri\GH22683 Y
Orthologs in non-Drosophila Dipterans (EOG6R50BT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010514   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005307   Anopheles gambiae Malaria mosquito  Agam\AGAP010586   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005868
Orthologs in non-Dipteran Insects (EOG62RC4N)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Acyrthosiphon pisum Pea aphid  Apim\ACYPI006813   Bombyx mori Silkmoth  Bmor\BGIBMGA011019   Pediculus humanus Human body louse  Phum\PHUM212240   Tribolium castaneum Red flour beetle  Tcas\TC011565
Orthologs in non-Insect Arthropods (EOG6GTHW7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\SMARCAD1   Ixodes scapularis Deer tick  Isca\ISCW018043
Orthologs in non-Arthropod Metazoa (EOG6ND07H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013261gn   Danio rerio Zebrafish  Drer\aimp1   Danio rerio Zebrafish  Drer\zgc:101853   Xenopus tropicalis Western clawed frog  Xtro\aimp1   Gallus gallus Domestic chicken  Ggal\AIMP1   Mus musculus House mouse  Mmus\Aimp1   Rattus norvegicus Norway rat  Rnor\Aimp1   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000028940   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042212   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029467   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000029417   Homo sapiens Human  Hsap\AIMP1
Human Orthologs (1)
Gene OMIM HGNC Hsap\AIMP1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15265 Drosophila sechellia Dsec\GM20651 Drosophila erecta Dere\GG10606 Drosophila yakuba Dyak\GE22699 Drosophila ananassae Dana\GF12729 Drosophila pseudoobscura pseudoobscura Dpse\GA20918 Drosophila persimilis Dper\GL10404 Drosophila willistoni Dwil\GK10745 Drosophila virilis Dvir\GJ21051 Drosophila mojavensis Dmoj\GI20611 Drosophila grimshawi Dgri\GH22683
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
Kyoto	123451 w1118; P{RS3}CG8235CB-5088-3
Genomic Clones ( 1 )
	BACR02C23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 9 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE55091
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH27932 GM17193 GM18158 GM21771 RE13107
Other clones	Dmel_dig_006493_0660_1739 Dmel_neb_011130_0397_2742 IP10657
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033351 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35892
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136582 RefSeq (Proteins) • NP_610426 DDBJ / EMBL / GenBank • AAF59019 AAL49102 AY071480 BI369016 Entrez Gene - A searchable database of RefSeq genes. • 35892 UniProtKB/TrEMBL • A1Z7K8 Q8SYK9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • tRNA-binding domain (IPR002547) Nucleic acid-binding, OB-fold (IPR012340) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE55091
Linkouts
	BioGRID - A database of protein and genetic interactions • 61730 DroID - A comprehensive database of gene and protein interactions. • FBgn0033351 DRSC - Results from RNAi screens. • FBgn0033351 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033351 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8235-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033351 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35892 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35892 modMine - Data generated by the modENCODE project. • FBgn0033351
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8235 (Loop et al., 2004)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Loop et al., 2004, BMC Genomics 5(1): 24 Transcriptional signature of an adult brain tumor in Drosophila. [FBrf0174362]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]
Curated genome annotation	Zhu, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126704]