A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Dmel\Or45a

General Information
SymbolDmel\Or45aSpeciesD. melanogaster
NameOdorant receptor 45aAnnotation symbolCG1978
Feature typeprotein_coding_geneFlyBase IDFBgn0033404
Gene Model StatusCurrent Stock availability 1 publicly available
Also Known As45a
Genomic Location
Chromosome (arm)2RRecombination map
Cytogenetic map45D1-45D1Sequence location2R:5,232,854..5,236,368 [+]

Genomic Maps

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Automatically generated summary

See sections below for more information
The gene Odorant receptor 45a is referred to in FlyBase by the symbol Dmel\Or45a (CG1978, FBgn0033404). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: olfactory receptor activity. There is experimental evidence that it is involved in the biological process: detection of chemical stimulus involved in sensory perception of smell. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Olfactory receptor, Drosophila. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1631438_a_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Or45a. Gene sequence location is 2R:5232854..5236368.
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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2013_03
FB2013_02
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hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
45D1-45D1  
Limits computationally determined from genome sequence between P{lacW}Pknk11209 and P{lacW}wunk09507&P{lacW}l(2)k12402k12402  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
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Please see the GBrowse view of Dmel\Or45a for information on other features GBrowse View Help
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0088503 FBtr0088558 FBtr0332997 FBtr0332996 FBpp0087587 FBpp0305212 FBpp0305211 FBti0145548 FBti0145185 FBti0052420
Comments on Gene Model
Gene model reviewed during 5.46
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0088503
  3461
  378
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0087587  
43.3  
378  
9.96  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
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Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
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Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
hide Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term
References
hide Expression Deduced from Reporters
hide High-Throughput Expression Data
Associated Tools
Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
hide FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)


   Styles
   Scales

Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 Very high 
log, scaled to maximum expression level
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 0.35
Larval Midgut
 
 1.2
Larval Hindgut
 
 3
Larval Malpighian Tubules
 
 2.5
Larval Fat Body
 
 5.4
Larval Salivary Gland
 
 0.7
Larval Trachea
 
 1.65
Larval Carcass
 
 2.275
Adult Head
 
 3.1
Adult Eye
 
 3.125
Adult Brain
 
 2.3
Adult Thoracic-Abdominal Ganglion
 
 4.5
Adult Crop
 
 3.1
Adult Midgut
 
 2.4
Adult Hindgut
 
 2
Adult Malpighian Tubules
 
 1.6
Adult Fat Body
 
 2.7
Adult Salivary Gland
 
 8.9
Adult Heart
 
 1.65
Adult VirginFemale Spermatheca
 
 1.4
Adult InseminatedFemale Spermatheca
 
 4.2
Adult Ovary
 
 1.1
Adult Testis
 
 3.2
Adult Male Accessory Gland
 
 5.1
Adult Carcass
 
 5.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 3.1
 
NA 
Eye
 
 3.125
 
NA 
Brain
 
 2.3
 
0.35 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 4.5
 
NA 
Crop
 
 3.1
 
1.2 
Midgut
 
 2.4
 
Hindgut
 
 2
 
2.5 
Malpighian Tubules
 
 1.6
 
5.4 
Fat Body
 
 2.7
 
0.7 
Salivary Gland
 
 8.9
 
NA 
Heart
 
 1.65
 
1.65 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 1.4
 
NA 
InseminatedFemale Spermatheca
 
 4.2
 
NA 
Ovary
 
 1.1
 
NA 
Testis
 
 3.2
 
NA 
Male Accessory Gland
 
 5.1
 
2.275 
Carcass
 
 5.8

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide modENCODE Anatomy RNA-Seq
hide modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
hide modENCODE Cell Lines RNA-Seq
hide modENCODE Treatments RNA-Seq
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
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Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
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hide Summary of Allele Phenotypes
Other Phenotypes
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 0 )
For All Classical Alleles Show

Allele of Or45aClassMutagenStocksKnown lesion
hide Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Or45aClassMutagenStocksKnown lesion
Or45aKK1051721 Yes
Or45aGD6020 Yes
Or45aNIG.1978R0 Yes
Or45aScer\UAS.T:Hsap\MYC0 Yes
hide Aneuploid Aberrations
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
GAL4 construct
characterization construct
Insertions
Type of insertions
Name
Expression data
hide Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
hide Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term
References
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term
References
inferred from electronic annotation with InterPro:IPR004117
inferred from electronic annotation with InterPro:IPR004117
inferred from sequence or structural similarity
Biological Process
CV term
References
inferred from sequence or structural similarity
Cellular Component
CV term
References
inferred from sequence or structural similarity
inferred from electronic annotation with InterPro:IPR004117
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
Or45a allele
Gene
References
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Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
hide OrthoDB Orthologs (25) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
hideOrthologs in Drosophila Species (EOG6NGH6N)
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly 
 
 
Drosophila simulans
 
Y
 
Drosophila sechellia
 
Y
 
Drosophila erecta
 
Y
 
Drosophila yakuba
 
Y
 
Drosophila ananassae
 
Y
 
Drosophila pseudoobscura pseudoobscura
 
Y
 
Drosophila persimilis
 
Y
 
Drosophila willistoni
 
Y
 
hideOrthologs in non-Drosophila Dipterans (EOG6P2Q9X)
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Anopheles gambiae
Malaria mosquito 
Y
Culex quinquefasciatus
Southern house mosquito 
Y
hideOrthologs in non-Dipteran Insects (EOG6RV1MS)
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Apis mellifera
Western honey bee 
Amel\GB45078
Y
Nasonia vitripennis
Parasitic wasp 
Nvit\Nasvi2EG037221
Y
Nasonia vitripennis
Parasitic wasp 
Nvit\Nasvi2EG037275
Y
Nasonia vitripennis
Parasitic wasp 
Nvit\Nasvi2EG036979
Y
Atta cephalotes
Leafcutter ant 
Acep\ACEP18688
Y
Atta cephalotes
Leafcutter ant 
Acep\ACEP18705
Y
Harpegnathos saltator
Jerdons jumping ant 
Hsal\HSAL23580
Y
Harpegnathos saltator
Jerdons jumping ant 
Hsal\HSAL13778
Y
Harpegnathos saltator
Jerdons jumping ant 
Hsal\HSAL13782
Y
Harpegnathos saltator
Jerdons jumping ant 
Hsal\HSAL13783
Y
Linepithema humile
Argentine ant 
Lhum\LH26051
Y
Tribolium castaneum
Red flour beetle 
Y
Tribolium castaneum
Red flour beetle 
Y
Tribolium castaneum
Red flour beetle 
Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
hide Human Orthologs (0)
Gene
OMIM
HGNC
hideAAA Orthologs (8) based on analysis using Dmel annotation version 4.3
Organism
Gene
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 1 )
VDRC
hide Genomic Clones ( 1 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 2 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for identity of: Or45a CG1978
Source for database merge of
Additional comments
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hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
hide Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym
Name Synonym
Odorant receptor 45a
 
Secondary FlyBase IDs
hide References ( 32 )
Generate a list of
List References by type
hide Recent research papers ( 2 )
Hoare et al., 2011, PLoS ONE 6(8): e22996
Modeling peripheral olfactory coding in Drosophila larvae. [FBrf0214697]
Montague et al., 2011, J. Neurosci. 31(21): 7891--7899
Similar odorants elicit different behavioral and physiological responses, some supersustained. [FBrf0213787]
hide Recent reviews (0)
All reviews listed in FlyBase were published before 2011