• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG1418

General Information
Symbol	Dmel\CG1418	Species	D. melanogaster
Name		Annotation symbol	CG1418
Feature type	protein_coding_gene	FlyBase ID	FBgn0033468
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	46C7-46C8	Sequence location	2R:5,851,342..5,852,567 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG1418 (FBgn0033468). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: Rab GTPase binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Prenylated rab acceptor PRA1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult male reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632991_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG1418. Gene sequence location is 2R:5851342..5852567.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN28393 HFA06447
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 46C7-46C8   Limits computationally determined from genome sequence between P{lacW}l(2)k08601k08601 and P{lacW}Adamk13906&P{EP}Pka-R2EP2162
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG1418 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG1418-RA FBtr0088440  NM_136695   1121   193
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG1418-PA   FBpp0087526   21.3   193   9.34     NP_610539   AAF58869
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Prenylated rab acceptor PRA1 (IPR004895)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142291   AE013599 AAF58869   AI296330   AI534919   BE662224   BE975214   BE976878   BF493124   BG633763   BH759245   BI365128   BI374443   BT011423   BT012668   BT125850   CO184903   CO187119   CO193062   CO268381   CO283321   CO288417   CO292813   CO301423   CO319027   EC070156   EC073479   EC089895   EC200280   EC208537   EC217829   EC235629   EL883398   EL883399
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A1Z823
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033468    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033468 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033468 expression level Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2567) embryo 02-04hr  (1340) embryo 04-06hr  (2055) embryo 06-08hr  (2754) embryo 08-10hr  (3073) embryo 10-12hr  (3709) embryo 12-14hr  (2904) embryo 14-16hr  (1205) embryo 16-18hr  (805) embryo 18-20hr  (572) embryo 20-22hr  (432) embryo 22-24hr  (456) larva L1  (1108) larva L2  (1556) larva L3 12hr old  (1201) larva L3 puffstage 1-2  (1084) larva L3 puffstage 3-6  (1608) larva L3 puffstage 7-9  (1809) white prepupae new  (1923) white prepupae 12hr  (2151) white prepupae 24hr  (3385) pupae 2d postWPP  (3933) pupae 3d postWPP  (3889) pupae 4d postWPP  (3670) adult male 01day  (7158) adult male 05day  (8400) adult male 30day  (8015) adult female 01day  (1060) adult female 05day  (1814) adult female 30day  (2012) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2567) embryo 02-04hr    1340 embryo 04-06hr  (2055) embryo 06-08hr  (2754) embryo 08-10hr  (3073) embryo 10-12hr  (3709) embryo 12-14hr  (2904) embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2  (1556) larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6  (1608) larva L3 puffstage 7-9  (1809) white prepupae new  (1923) white prepupae 12hr  (2151) white prepupae 24hr  (3385) pupae 2d postWPP  (3933) pupae 3d postWPP  (3889) pupae 4d postWPP  (3670) adult male 01day  (7158) adult male 05day  (8400) adult male 30day  (8015) adult female 01day    1060 adult female 05day  (1814) adult female 30day  (2012) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033468 expression level Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2567) embryo 02-04hr  (1340) embryo 04-06hr  (2055) embryo 06-08hr  (2754) embryo 08-10hr  (3073) embryo 10-12hr  (3709) embryo 12-14hr  (2904) embryo 14-16hr  (1205) embryo 16-18hr  (805) embryo 18-20hr  (572) embryo 20-22hr  (432) embryo 22-24hr  (456) larva L1  (1108) larva L2  (1556) larva L3 12hr old  (1201) larva L3 puffstage 1-2  (1084) larva L3 puffstage 3-6  (1608) larva L3 puffstage 7-9  (1809) white prepupae new  (1923) white prepupae 12hr  (2151) white prepupae 24hr  (3385) pupae 2d postWPP  (3933) pupae 3d postWPP  (3889) pupae 4d postWPP  (3670) adult male 01day  (7158) adult male 05day  (8400) adult male 30day  (8015) adult female 01day  (1060) adult female 05day  (1814) adult female 30day  (2012) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2567) embryo 02-04hr    1340 embryo 04-06hr  2055 embryo 06-08hr  (2754) embryo 08-10hr  (3073) embryo 10-12hr  (3709) embryo 12-14hr  (2904) embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2  1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6  1608 larva L3 puffstage 7-9  1809 white prepupae new  1923 white prepupae 12hr  2151 white prepupae 24hr  (3385) pupae 2d postWPP  (3933) pupae 3d postWPP  (3889) pupae 4d postWPP  (3670) adult male 01day  (7158) adult male 05day  (8400) adult male 30day  (8015) adult female 01day    1060 adult female 05day  1814 adult female 30day  2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2567 embryo 02-04hr    1340 embryo 04-06hr    2055 embryo 06-08hr    2754 embryo 08-10hr    3073 embryo 10-12hr    3709 embryo 12-14hr    2904 embryo 14-16hr    1205 embryo 16-18hr    805 embryo 18-20hr    572 embryo 20-22hr    432 embryo 22-24hr    456 larva L1    1108 larva L2    1556 larva L3 12hr old    1201 larva L3 puffstage 1-2    1084 larva L3 puffstage 3-6    1608 larva L3 puffstage 7-9    1809 white prepupae new    1923 white prepupae 12hr    2151 white prepupae 24hr    3385 pupae 2d postWPP    3933 pupae 3d postWPP    3889 pupae 4d postWPP    3670 adult male 01day    7158 adult male 05day    8400 adult male 30day    8015 adult female 01day    1060 adult female 05day    1814 adult female 30day    2012 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033468    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033468 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult male reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult female reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033468 expression level Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland    1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis    1359 Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland  529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland  (1042.7) Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis  (1359) Adult Male Accessory Gland  (882.4) Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland  1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis  (1359) Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland    1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis    1359 Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033468 expression level Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland    1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis    1359 Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland  529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland  (1042.7) Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis  (1359) Adult Male Accessory Gland  (882.4) Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland  1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis  1359 Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    97.175 Larval Midgut    40.2 Larval Hindgut    108.6 Larval Malpighian Tubules    57.5 Larval Fat Body    173.3 Larval Salivary Gland    529.2 Larval Trachea    129.425 Larval Carcass    124.925 Adult Head    102.4 Adult Eye    91.975 Adult Brain    85.4 Adult Thoracic-Abdominal Ganglion    84.5 Adult Crop    175.4 Adult Midgut    68.1 Adult Hindgut    113.1 Adult Malpighian Tubules    117.6 Adult Fat Body    115.4 Adult Salivary Gland    1042.7 Adult Heart    108.8 Adult VirginFemale Spermatheca    213.1 Adult InseminatedFemale Spermatheca    245.4 Adult Ovary    176.2 Adult Testis    1359 Adult Male Accessory Gland    882.4 Adult Carcass    103.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    102.4   NA  Eye    91.975   NA  Brain    85.4   97.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    84.5   NA  Crop    175.4   40.2  Midgut    68.1   108.6  Hindgut    113.1   57.5  Malpighian Tubules    117.6   173.3  Fat Body    115.4   529.2  Salivary Gland    1042.7   NA  Heart    108.8   129.425  Trachea    NA   NA  VirginFemale Spermatheca    213.1   NA  InseminatedFemale Spermatheca    245.4   NA  Ovary    176.2   NA  Testis    1359   NA  Male Accessory Gland    882.4   124.925  Carcass    103.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033468 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1418-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG1418GD4532 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG1418 Class Mutagen Stocks Known lesion CG1418CB-5355-3 1 -- CG1418KG00559 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG1418 Class Mutagen Stocks Known lesion CG1418GD4532 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG1418KK108393 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1418GD16470 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4532} NA P{GD16470} NA P{KK108393} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG1418CB-5355-3 NA P{SUPor-P}CG1418KG00559 NA P{wHy}DG25306 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
Rab GTPase binding inferred from sequence or structural similarity with EMBL:AF120162 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG1418 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61863 DroID - A comprehensive database of gene and protein interactions. • FBgn0033468 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36035
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11298 Dere\GG25243 Dgri\GH20444 Dmoj\GI19271 Dper\GL17704 Dpse\GA12807 Dsec\GM20563 Dsim\GD10035 Dvir\GJ22148 Dwil\GK15829 Dyak\GE21886
Curated drosophilid orthologs	Dere\GG25243   Dpse\GA12807
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010794-PA Aedes aegypti (mosquito) AGAP003662-PA Anopheles gambiae (mosquito) XP_393100.1 Apis mellifera (honey bee) At5g07110.1 Arabidopsis thaliana (wall cress) 14138 Batrachochytrium dendrobatidis (chytrid fungus) 125634 Branchiostoma floridae (lancelet) 261071 Branchiostoma floridae (lancelet) ENSBTAP00000024793 Bos taurus (bovine) CAF0007072 Candida albicans (a form of yeast) ENSCAFP00000007398 Canis familiaris (dog) CAGL0G01452g Candida glabrata (haploid yeast) Chro.80192 Cryptosporidium hominis (obligate parasite) cn09020 Cryptococcus neoformans (yeast-like fungus) cgd8_1640 Cryptosporidium parvum (protozoan parasite) CPIJ009442 Culex pipens (mosquito) ENSCPOP00000021170 Cavia porcellus (guinea pig) 171434 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000017092 Ciona savignyi (sedentary tunicate) 19146 Capitella spl (polychaete worm) DDB0206263 Dictyostelium discoideum (amoeba) 47113 Daphnia pulex (daphnia) ENSDARP00000028630 Danio rerio (zebra fish) ENSGACP00000012542 Gymnopilus aculeatus (mushroom) 169884 Hypsipyla robusta (cedar shoot borer) ENSP00000222008 Homo sapiens (human) ISCW006473-PA Ixodes scapularis (deer tick) KLLA0F03905g Kluyveromyces lactis (yeast) 153327 Lottia gigantea (owl limpet) LmjF33.1530 Leishmania major (virus) 33098 Monocosta brevicollis (choanoflagellate) ENSMMUP00000022939 Macaca mulatta (rhesus monkey) ENSMUSP00000076227 Mus musculus (house mouse) 110754 Nematostella vectensis (starlet anemone) XP_001608099.1 Nasonia vitripennis (wasp) ENSOANP00000029089 Ornithorynchus anatinus (platypus) ENSORLP00000016547 Oryzias latipes (japanese killifish) LOC_Os11g01610.1 Oryza sativa (asian rice) LOC_Os12g01690.1 Oryza sativa (asian rice) 12748 Ostreococcus tauri (green alga) PHUM004777-PA Pediculus humanus (human body louse) 119721 Physcomitrella patens (moss) ENSPPYP00000011228 Pongo pygmaeus (orangutan) 76177 Phytophthora ramorum (sudden oak death pathogen) 134231 Phytophthora sojae (root rot pathogen) 809747 Populus trichocarpa (black cottonwood) ENSPTRP00000018962 Pan troglodytes (chimpanzee) ENSRNOP00000027435 Rattus norvegicus (norway rat) 5028156 Sorghum bicolor (sorghum) YNL044W Saccharomyces cerevisiae (budding yeast) XP_001179602.1 Strongylocentrotus purpuratus (purple sea urchin) 55970 Trichoplax adhaerens (metazoa) XP_968976.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010828 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020300 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000051415 Xenopus tropicalis (frog) YALI0A09845g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10283 LH17118 ISCW006473 FBgn0239128 FBgn0217832 FBgn0209262 FBgn0181810 FBgn0175445 JGI_V11_47113 FBgn0064441 FBgn0155307 FBgn0142010 FBgn0127907 FBgn0064646 FBgn0088338 CPIJ009442 BGIBMGA007566 GB17986 AGAP003662 AAEL010794 PB22370 PHUM424150 GLEAN_14897
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	13680 y1 w67c23; P{SUPor-P}CG1418KG00559
Kyoto	123582 w1118; P{RS3}CG1418CB-5355-3
VDRC	v104571 P{KK108393}VIE-260B v37728 w1118; P{GD4532}v37728 v37729 w1118; P{GD4532}v37729/CyO
Genomic Clones ( 2 )
	BACR01L01 BACR06J01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 28 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT01420 AT15204 RE50359
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT29491 LP10191 RE62033 SD01205
Other clones	43500 58500 72375 175066 bs32b01 bs39h04 bs57b04 CK01.29D.D10 CK01.86D.F4 CK01.119D.C11 CK01371 EC28768 EC35066 EK026335 EK068454 EK091212 EK162843 EK180930 EK201016 EK276025 IP13077
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033468 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36035
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136695 RefSeq (Proteins) • NP_610539 DDBJ / EMBL / GenBank • AAF58869 BE662224 BF493124 BH759245 BI365128 Entrez Gene - A searchable database of RefSeq genes. • 36035 UniProtKB/TrEMBL • A1Z823
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Prenylated rab acceptor PRA1 (IPR004895)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61863 DroID - A comprehensive database of gene and protein interactions. • FBgn0033468 DRSC - Results from RNAi screens. • FBgn0033468 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033468 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1418-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033468 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36035 InParanoid A subset of ortholog calls from InParanoid. • AAEL010794-PA Aedes aegypti (mosquito) AGAP003662-PA Anopheles gambiae (mosquito) XP_393100.1 Apis mellifera (honey bee) At5g07110.1 Arabidopsis thaliana (wall cress) 14138 Batrachochytrium dendrobatidis (chytrid fungus) 125634 Branchiostoma floridae (lancelet) 261071 Branchiostoma floridae (lancelet) ENSBTAP00000024793 Bos taurus (bovine) CAF0007072 Candida albicans (a form of yeast) ENSCAFP00000007398 Canis familiaris (dog) CAGL0G01452g Candida glabrata (haploid yeast) Chro.80192 Cryptosporidium hominis (obligate parasite) cn09020 Cryptococcus neoformans (yeast-like fungus) cgd8_1640 Cryptosporidium parvum (protozoan parasite) CPIJ009442 Culex pipens (mosquito) ENSCPOP00000021170 Cavia porcellus (guinea pig) 171434 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000017092 Ciona savignyi (sedentary tunicate) 19146 Capitella spl (polychaete worm) DDB0206263 Dictyostelium discoideum (amoeba) 47113 Daphnia pulex (daphnia) ENSDARP00000028630 Danio rerio (zebra fish) ENSGACP00000012542 Gymnopilus aculeatus (mushroom) 169884 Hypsipyla robusta (cedar shoot borer) ENSP00000222008 Homo sapiens (human) ISCW006473-PA Ixodes scapularis (deer tick) KLLA0F03905g Kluyveromyces lactis (yeast) 153327 Lottia gigantea (owl limpet) LmjF33.1530 Leishmania major (virus) 33098 Monocosta brevicollis (choanoflagellate) ENSMMUP00000022939 Macaca mulatta (rhesus monkey) ENSMUSP00000076227 Mus musculus (house mouse) 110754 Nematostella vectensis (starlet anemone) XP_001608099.1 Nasonia vitripennis (wasp) ENSOANP00000029089 Ornithorynchus anatinus (platypus) ENSORLP00000016547 Oryzias latipes (japanese killifish) LOC_Os11g01610.1 Oryza sativa (asian rice) LOC_Os12g01690.1 Oryza sativa (asian rice) 12748 Ostreococcus tauri (green alga) PHUM004777-PA Pediculus humanus (human body louse) 119721 Physcomitrella patens (moss) ENSPPYP00000011228 Pongo pygmaeus (orangutan) 76177 Phytophthora ramorum (sudden oak death pathogen) 134231 Phytophthora sojae (root rot pathogen) 809747 Populus trichocarpa (black cottonwood) ENSPTRP00000018962 Pan troglodytes (chimpanzee) ENSRNOP00000027435 Rattus norvegicus (norway rat) 5028156 Sorghum bicolor (sorghum) YNL044W Saccharomyces cerevisiae (budding yeast) XP_001179602.1 Strongylocentrotus purpuratus (purple sea urchin) 55970 Trichoplax adhaerens (metazoa) XP_968976.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010828 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020300 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000051415 Xenopus tropicalis (frog) YALI0A09845g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36035 modMine - Data generated by the modENCODE project. • FBgn0033468 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10283 LH17118 ISCW006473 FBgn0239128 FBgn0217832 FBgn0209262 FBgn0181810 FBgn0175445 JGI_V11_47113 FBgn0064441 FBgn0155307 FBgn0142010 FBgn0127907 FBgn0064646 FBgn0088338 CPIJ009442 BGIBMGA007566 GB17986 AGAP003662 AAEL010794 PB22370 PHUM424150 GLEAN_14897
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG1418 (Hollien and Weissman, 2006, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Bergman et al., 2002, GenomeBiol. 3(12): RESEARCH0086 Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. [FBrf0155470]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Hollien and Weissman, 2006, Science 313(5783): [FBrf0199122] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Gelbart, 2008.3.31, DG.xml DG.xml [FBrf0204101] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection. Deletion Generator Project genomic insertion collection. [FBrf0188490] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]