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Gene Dmel\CAP

General Information
Symbol	Dmel\CAP	Species	D. melanogaster
Name	CAP	Annotation symbol	CG18408
Feature type	protein_coding_gene	FlyBase ID	FBgn0033504
Gene Model Status	Current	Stock availability	22 publicly available
Also Known As	DCAP, Rexin
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	46F9-47A1	Sequence location	2R:6,156,521..6,194,529 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: vinculin binding. The biological processes in which it is involved are not known. 31 alleles are reported. No phenotypic data is available. It has 23 annotated transcripts and 23 annotated polypeptides. Protein features are: Neutrophil cytosol factor 2 p67phox; Sorbin-like; Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, inseminated spermatheca, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules, larval salivary gland, larval trachea, adult female reproductive system, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1633353_s_at completely aligns to an exonic region of only a subset of 16 of the 17 FlyBase-annotated transcript isoforms of CAP. Gene sequence location is 2R:6156521..6194529.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Controlled Vocabulary Terms sensory perception of sound sensory perception of mechanical stimulus muscle attachment Alleles CAP[C.Scer\UAS.T:Hsap\MYC] CAP[42b] CAP[E.Scer\UAS.T:Hsap\MYC] CAP[49a] CAP[49e] CAP[DeltaSoHo.C.Scer\UAS.T:Hsap\MYC] CAP[miRNA.Scer\UAS] Transgenic Constructs P{UAS-CAP.C} P{UAS-CAP.E} P{UAS-CAP.C.DeltaSoHo} P{UAS-CAP.miRNA}
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 46F9-47A1   Limits computationally determined from genome sequence between P{lacW}Hr46k10308 and P{PZ}lola00349&P{EP}lolaEP952
Experimentally Determined Cytological Location
Cytogenetic map Notes References 46F9-47A1     (Yamazaki and Nusse, 2002)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CAP for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model includes transcripts encoding non-overlapping portions of the full CDS. Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters. Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CAP-RA FBtr0088341  NM_136727   8447   2376 CAP-RB FBtr0088344  NM_165760   6205   1734 CAP-RC FBtr0088343  NM_165757   3322   824 CAP-RD FBtr0088345  NM_165761   2376   527 CAP-RE FBtr0088346  NM_165762   1788   313 CAP-RF FBtr0088342  NM_165758   3510   811 CAP-RG FBtr0088340  NM_165759   3521   500 CAP-RH FBtr0088339  NM_136728   2578   500 CAP-RI FBtr0088338  NM_136726   2663   639 CAP-RJ FBtr0088347  NM_206073   2702   565 CAP-RK FBtr0299825  NM_001144164   3301   630 CAP-RL FBtr0299826  NM_001144165   8414   2365 CAP-RN FBtr0299828  NM_001144167   3157   313 CAP-RO FBtr0299829  NM_001144168   2824   630 CAP-RP FBtr0299830  NM_001144169   6531   1883 CAP-RQ FBtr0301131  NM_001144166   8555   2412 CAP-RR FBtr0301965  NM_001169639   6232   1743 CAP-RS FBtr0306688  NM_001259309   2384   554 CAP-RU FBtr0306690  NM_001259311   2872   674 CAP-RV FBtr0306691  NM_001259312   8693   2458 CAP-RW FBtr0336694  NM_001273930   5528   1586 CAP-RX FBtr0336695  NM_001259310   8834   2505 CAP-RY FBtr0336696  NM_001273931   8546   2409
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CAP-PA   FBpp0087430   267.7   2376   5.42     NP_610571   AAF58816 CAP-PB   FBpp0087433   196.9   1734   10.23     NP_724913   AAM68780 CAP-PC   FBpp0087432   92.6   824   9.12     NP_724910   AAM68778 CAP-PD   FBpp0087434   60.5   527   8.86     NP_724914   AAM68781 CAP-PE   FBpp0087435   35.5   313   8.42     NP_724915   AAM68782 CAP-PF   FBpp0087431   91.3   811   9.20     NP_724911   AAF58815 CAP-PG   FBpp0087429   56.5   500   7.34     NP_724912   AAM68779 CAP-PH   FBpp0087428   56.5   500   7.34     NP_610572   AAF58814 CAP-PI   FBpp0087427   72.0   639   9.02     NP_610570   AAF58813 CAP-PJ   FBpp0087436   63.9   565   8.35     NP_995795   AAS64879 CAP-PK   FBpp0289103   71.7   630   8.64     NP_001137636   ACL83090 CAP-PL   FBpp0289104   266.3   2365   5.49     NP_001137637   ACL83091 CAP-PN   FBpp0289106   35.5   313   8.42     NP_001137639   ACL83093 CAP-PO   FBpp0289107   71.7   630   8.64     NP_001137640   ACL83094 CAP-PP   FBpp0289108   212.0   1883   5.11     NP_001137641   ACL83095 CAP-PQ   FBpp0290354   272.1   2412   5.60     NP_001137638   ACL83092 CAP-PR   FBpp0291177   198.0   1743   10.20     NP_001163110   ACZ94385 CAP-PS   FBpp0297627   62.5   554   8.95     NP_001246238   AFH07993 CAP-PU   FBpp0297629   76.9   674   9.03     NP_001246240   AFH07995 CAP-PV   FBpp0297630   277.5   2458   5.65     NP_001246241   AFH07996 CAP-PW   FBpp0307675   179.0   1586   6.94     NP_001260859   AGB93392 CAP-PX   FBpp0307676   282.6   2505   5.79     NP_001246239   AFH07994 CAP-PY   FBpp0307677   271.5   2409   5.47     NP_001260860   AGB93393
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Neutrophil cytosol factor 2 p67phox (IPR000108) Src homology-3 domain (IPR001452) Sorbin-like (IPR003127)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA979480   AE013599 AAF58813   AE013599 AAF58814   AE013599 AAF58815   AE013599 AAF58816   AE013599 AAM68778   AE013599 AAM68779   AE013599 AAM68780   AE013599 AAM68781   AE013599 AAM68782   AE013599 AAS64879   AB053478 BAB62017   AB053479 BAB62018   AB053480 BAB62019   AB053481 BAB62020   AB053482 BAB62021   AE013599 ACL83090   AE013599 ACL83091   AE013599 ACL83092   AE013599 ACL83093   AE013599 ACL83094   AE013599 ACL83095   AE013599 ACZ94385   AE013599 AFH07993   AE013599 AFH07994   AE013599 AFH07995   AE013599 AFH07996   AE013599 AGB93392   AE013599 AGB93393   AI260907   AI297346   AI403448   AI519241   AI532298   AI533344   AI542309   AI542877   AW944151   AW944326   AY061565 AAL29113   BG638924   BG639916   BH011472   BH759203   BH840393   BI142063   BI164275   BI164332   BI164494   BI164754   BI166170   BI168848   BI169627   BI170240   BI212212   BI214936   BI230372   BI231338   BI231554   BI356647   BI368027   BI370161   BI371458   BI485515   BI565422   BI577591   BI605030   BI614819   BI617813   BI619468   BI620404   BI621843   BI624873   BI629329   BI630264   BP546812   BP546895   BQ103034   BT001690 AAN71445   BT001858 AAN71620   BT003217 AAO24972   BT003435 AAO39438   BT029611   BT029638   BT031113   BT120189   CK133330   CK659628   CL610202   CO178552   CO186488   CO186631   CO187834   CO262501   CO263833   CO270894   CO272972   CO273917   CO275237   CO280781   CO281870   CO283194   CO283662   CO284574   CO285365   CO286212   CO288827   CO289364   CO291395   CO291970   CO292140   CO292926   CO295033   CO303076   CO310044   CO310193   CO311018   CO313186   CO320927   CO322278   CO322326   CO324234   CO328335   CO328382   CO328847   CO330728   CO330856   CO339800   CO340091   CO341249   CO343871   CZ477917   CZ480353   CZ481743   CZ483961   CZ484600   CZ484601   EC058793   EC060531   EC063101   EC070450   EC075154   EC075981   EC076136   EC077001   EC079573   EC080255   EC081143   EC081602   EC086233   EC088045   EC209296   EC216331   EC221002   EC229235   EC234309   EC236967   EC237431   EC239291   EC242872   EC242873   EC246981   EC247137   EC248245   EC251629   EC252506   EC256625   EC257015   EC258256   EC258705   EC264544   EL875232   EL875360   EL884206   EL886437   EL886557   EL886774   ES693386   ES696193   ES696194   ES696195   ES696197   ES696199   ES696200   ES696201   ES696202   ES696203   ES696204   ES696205   ES696206   ES696208   ES696209   ES696210   ES696211   ES696212   EV588993   GH947493
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86P80 Q966U7 Q966V0 Q7K1M7 A1Z870 A1Z869 Q7JR75 A1Z867 A1Z872 A1Z871 A1Z866 B7YZD9 B7YZD8 B7YZE0 Q8IGN4 Q966U8 Q966V1 Q966U9 Q8IGB7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   garland cell primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   amnioserosa   (Fisher et al., 2012) dorsal sensory complex proper primordium   (Fisher et al., 2012) Comment:reported as dorsal/lateral sensory complexes embryonic head epidermis   (Fisher et al., 2012) embryonic/larval dorsal vessel   (Fisher et al., 2012) embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) sensory nervous system primordium   (Fisher et al., 2012) ventral sensory complex primordium   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, inseminated spermatheca, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules, larval salivary gland, larval trachea, adult female reproductive system, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut    1294 Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass    1435.525 Adult Head    766.9 Adult Eye    1256.575 Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop    2047.4 Adult Midgut    544.3 Adult Hindgut    1361.7 Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland    3110 Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut  (760.8) Larval Hindgut  (1294) Larval Malpighian Tubules    262.5 Larval Fat Body  (688.8) Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass  (1435.525) Adult Head  (766.9) Adult Eye  (1256.575) Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop  (2047.4) Adult Midgut  (544.3) Adult Hindgut  (1361.7) Adult Malpighian Tubules  (685.1) Adult Fat Body  (817.6) Adult Salivary Gland  (3110) Adult Heart  (918.75) Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca  (575.2) Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland  (905.3) Adult Carcass  (915) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut  (1294) Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass  (1435.525) Adult Head    766.9 Adult Eye  (1256.575) Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop  (2047.4) Adult Midgut    544.3 Adult Hindgut  (1361.7) Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland  (3110) Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut    1294 Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass    1435.525 Adult Head    766.9 Adult Eye    1256.575 Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop    2047.4 Adult Midgut    544.3 Adult Hindgut    1361.7 Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland    3110 Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut    1294 Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass    1435.525 Adult Head    766.9 Adult Eye    1256.575 Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop    2047.4 Adult Midgut    544.3 Adult Hindgut    1361.7 Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland    3110 Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut  760.8 Larval Hindgut  (1294) Larval Malpighian Tubules    262.5 Larval Fat Body  688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass  (1435.525) Adult Head  766.9 Adult Eye  (1256.575) Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop  (2047.4) Adult Midgut  544.3 Adult Hindgut  (1361.7) Adult Malpighian Tubules  685.1 Adult Fat Body  (817.6) Adult Salivary Gland  (3110) Adult Heart  (918.75) Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca  575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland  (905.3) Adult Carcass  (915) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut  1294 Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass  1435.525 Adult Head    766.9 Adult Eye  1256.575 Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop  (2047.4) Adult Midgut    544.3 Adult Hindgut  1361.7 Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland  (3110) Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.1 Larval Midgut    760.8 Larval Hindgut    1294 Larval Malpighian Tubules    262.5 Larval Fat Body    688.8 Larval Salivary Gland    111.2 Larval Trachea    162.775 Larval Carcass    1435.525 Adult Head    766.9 Adult Eye    1256.575 Adult Brain    302.7 Adult Thoracic-Abdominal Ganglion    406.4 Adult Crop    2047.4 Adult Midgut    544.3 Adult Hindgut    1361.7 Adult Malpighian Tubules    685.1 Adult Fat Body    817.6 Adult Salivary Gland    3110 Adult Heart    918.75 Adult VirginFemale Spermatheca    402.9 Adult InseminatedFemale Spermatheca    575.2 Adult Ovary    135.2 Adult Testis    168.7 Adult Male Accessory Gland    905.3 Adult Carcass    915 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    766.9   NA  Eye    1256.575   NA  Brain    302.7   395.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    406.4   NA  Crop    2047.4   760.8  Midgut    544.3   1294  Hindgut    1361.7   262.5  Malpighian Tubules    685.1   688.8  Fat Body    817.6   111.2  Salivary Gland    3110   NA  Heart    918.75   162.775  Trachea    NA   NA  VirginFemale Spermatheca    402.9   NA  InseminatedFemale Spermatheca    575.2   NA  Ovary    135.2   NA  Testis    168.7   NA  Male Accessory Gland    905.3   1435.525  Carcass    915 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult  (33) carcass, 4-day adult  (27) carcass, 20-day adult  26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult  (33) carcass, 4-day adult  27 carcass, 20-day adult  26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    4 central nervous system, pupae P8    14 head, virgin 1-day female    17 head, virgin 4-day female    19 head, virgin 20-day female    14 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    14 head, mated 1-day male    25 head, mated 4-day male    23 head, mated 20-day male    25 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    10 digestive system, 4-day adult    15 digestive system, 20-day adult    13 fat body, larvae L3 wandering    5 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    10 carcass, 1-day adult    33 carcass, 4-day adult    27 carcass, 20-day adult    26 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    2 accessory gland, mated 4-day male    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr  (33) embryo 18-20hr  (54) embryo 20-22hr  (42) embryo 22-24hr  (40) larva L1  26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr  (33) embryo 18-20hr  (54) embryo 20-22hr  (42) embryo 22-24hr  (40) larva L1  26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    2 embryo 10-12hr    4 embryo 12-14hr    10 embryo 14-16hr    24 embryo 16-18hr    33 embryo 18-20hr    54 embryo 20-22hr    42 embryo 22-24hr    40 larva L1    26 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    4 white prepupae 24hr    4 pupae 2d postWPP    23 pupae 3d postWPP    19 pupae 4d postWPP    15 adult male 01day    20 adult male 05day    22 adult male 30day    21 adult female 01day    12 adult female 05day    4 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3  (28) eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3  28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    7 Schneider line 2 Sg4    3 embryonic 1182-4H    2 embryonic GM2    6 embryonic Kc167    1 embryonic S1    1 embryonic S3    0 leg disc CME L1    5 wing disc CME-W2    1 wing disc ML-DmD8    1 wing disc ML-DmD9    5 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    3 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    28 eye-antennal disc ML-DmD11    2 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    3 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    7 ovary fGS/OSS    1 ovary OSC    1 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    14 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    18 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • IP16877 LP11629 SD03761 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033504 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18408-RI FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CAP Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | partially, with CAP77-284 CAPa.77-284 lethal | embryonic stage | partially, with CAPa.77-284 CAP77-284 viable CAP42b CAP49e CAPCA06924 CAPCA07185 CAPEY08073 CAPEY16176 viable, with Scer\GAL4pnr-MD237 CAPGD8545 Sterility Allele fertile CAP42b CAP49e CAPEY08073 CAPEY16176 Other Phenotypes Allele auditory perception defective | adult stage CAP49e auditory perception defective | adult stage, with Scer\GAL4nompA.cK CAPmiRNA.Scer\UAS behavior defective | third instar larval stage CAP42b CAP49e behavior defective | third instar larval stage, with Scer\GAL4nompA.cK CAPmiRNA.Scer\UAS neuroanatomy defective | adult stage CAP49e Phenotype manifest in Allele Johnston organ CAP49e muscle attachment site, with Scer\GAL4Mef2.PR CAPE.Scer\UAS.T:Hsap\MYC muscle attachment site | larval stage CAP49e CAP42b muscle attachment site | larval stage, with Scer\GAL4Mef2.PR CAPmiRNA.Scer\UAS scolopale cell CAP49e
Classical Alleles ( 23 )
For All Classical Alleles Show
Allele of CAP Class Mutagen Stocks Known lesion CAP5-HA-1965 1 -- CAPBG02184 P-element activity 1 Yes CAPe00006 piggyBac transposase 1 -- CAPe02572 piggyBac transposase 1 -- CAPe03984 piggyBac transposase 1 -- CAPEY08073 P-element activity 1 -- CAPEY16176 P-element activity 1 -- CAPEY21786 P-element activity 1 -- CAPf01489 piggyBac transposase 1 -- CAPKG00083 P-element activity 1 -- CAPKG00192 1 -- CAPKG00308 P-element activity 1 -- CAPMB04531 1 -- CAPMI02963 1 -- CAPMI03547 1 -- CAPMI03930 1 -- CAPNP7370 1 -- CAP42b amorphic allele - molecular evidence P-element activity 0 Yes CAP49e amorphic allele - molecular evidence P-element activity 0 Yes CAP49a P-element activity 0 Yes CAPCA06924 P-element activity 0 Yes CAPCA07185 P-element activity 0 Yes CAPf02098 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 15 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CAP Class Mutagen Stocks Known lesion CAPGD8545 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CAPGL00573 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CAPHM05250 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CAPHMS01551 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CAPKK107936 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CAP77-284 in vitro construct - RNAi 0 Yes CAPa.77-284 in vitro construct - RNAi 0 Yes CAPC.Scer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes CAPE.Scer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes CAPmiRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes CAPNIG.18408R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CAPNIG.3451R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CAPS.hs in vitro construct - regulatory fusion 0 Yes CAPS.Scer\UAS in vitro construct - regulatory fusion 0 Yes CAPΔSoHo.C.Scer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8545} NA P{KK107936} NA P{NIG.3451R} NA P{NIG.18408R} NA P{TRiP.GL00573} NA P{TRiP.HM05250} NA P{TRiP.HMS01551} NA P{UAS-CAP.C.ΔSoHo} NA P{UAS-CAP.C} NA P{UAS-CAP.E} NA P{UAS-CAP.miRNA} NA P{UAS-CAP.S} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CAPMI02963 NA Mi{MIC}CAPMI03547 NA Mi{MIC}CAPMI03930 NA P{GT1}CAPBG02184 NA P{PTT-GA}CAPCA06924 NA P{PTT-GA}CAPCA07185 NA P{RS5}CAP5-HA-1965 NA P{SUPor-P}CAPKG00083 NA P{SUPor-P}CAPKG00308 NA P{SUPor-P}hebeKG00192 NA PBac{RB}CAPe00006 NA PBac{RB}CAPe02572 NA PBac{RB}CAPe03984 NA PBac{WH}CAPf01489 NA PBac{WH}CAPf02098 NA insertion of mobile activating element P{EPgy2}CAPEY08073 NA P{EPgy2}CAPEY16176 NA P{EPgy2}CAPEY21786 NA insertion of enhancer trap P{lacW}l(2)SH1724SH1724 No insertion of enhancer trap binary system Mi{ET1}CAPMB04531 No P{GawB}CAPNP7370 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
muscle attachment inferred from mutant phenotype (Bharadwaj et al., 2013) sensory perception of mechanical stimulus inferred from mutant phenotype (Bharadwaj et al., 2013) sensory perception of sound inferred from mutant phenotype (Bharadwaj et al., 2013)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
vinculin binding inferred from sequence or structural similarity with EMBL:AF064807 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
focal adhesion inferred from sequence or structural similarity with EMBL:AF064807 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CAP pull down, western blot (Yamazaki and Nusse, 2002) CAP - Axn pull down, western blot, two hybrid (Yamazaki and Nusse, 2002) CAP - CG10306 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - CG13900 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - CG16789 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - CG7194 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - CG9769 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Int6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - NHP2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Npc2b anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - RpL35A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Tango7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - Zn72D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - eIF3-S8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - homer anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - mRpS24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CAP - vig anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CAP allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61904 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033504 DroID - A comprehensive database of gene and protein interactions. • FBgn0033504 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36084 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • A1Z872
Orthologs
OrthoDB Orthologs (5) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG63V0DT Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG63V0DT)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CAP     Drosophila simulans   Dsim\GD10729     Drosophila sechellia   Dsec\GM21205     Drosophila yakuba   Dyak\GE19352     Drosophila willistoni   Dwil\GK17789
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (3) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila willistoni Dwil\GK17791 Drosophila virilis Dvir\GJ22205 Drosophila grimshawi Dgri\GH21781
Stocks & Reagents
Stocks Listed in FlyBase ( 22 )
Bloomington	12596 w1118; P{GT1}CAPBG02184 36389 y1 w*; Mi{MIC}CAPMI03930 20017 y1 w67c23; P{EPgy2}CAPEY08073 21195 y1 w67c23; P{EPgy2}CAPEY16176 22508 y1 w67c23; P{EPgy2}CAPEY21786
Harvard	- PBac{RB}CAPe00006 - PBac{RB}CAPe02572 - PBac{RB}CAPe03984 - PBac{WH}CAPf01489
Kyoto	125500 w1118; P{RS5}CAP5-HA-1965
VDRC	v106309 P{KK107936}VIE-260B v19054 w1118; P{GD8545}v19054
	More stocks available...
Genomic Clones ( 1 )
	BACR48F07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 132 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP17077 IP17177 LP11629 RE10170 RE58362 RH64582 SD03761 SD16465
Other clones	DPiM_RE58362 DPiM_RH64582 IP16877
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH22885 LD34077 LP04911 LP17522 RE03923 RE03987 RE04187 RE04492 RE06212 RE09741 RE10858 RE11631 RE17258 RE20791 RE21091 RE42836 RE53928 RE56578 RE68861 RE71293 RH44293 RH48258 RH50509 RH51547 RH53263 RH58174 RH59269 RH63193 RH70543 SD05124 SD09382 SD16060
Other clones	9914 11723 14433 52621 62796 65624 71402 72624 73446 97595 100443 103160 104267 106262 117946 120307 184070 192685 214211.38 214275.7 214315.39 214379.32 214479.36 214505.28 522407 CK01.21D.A6 CK01.23D.C10 CK01.71D.A8 CK01.88A.E2 CK01.90A.F8 CK01.101C.D1 CK01.110C.F6 CK01.112A.B10 Dmel_neb_014873_0118_1766 EK020227 EK021641 EK033841 EK057025 EK062103 EK069449 EK070856 EK078613 EK085610 EK100942 EK109025 EK112627 EK116838 EK136602 EK154840 EK158957 EK162458 EK164026 EK166327 EK168837 EK187810 EK187907 EK193032 EK198905 EK199317 EK201232 EK208405 EK220321 EK220702 EK223153 EK231831 EK239847 EK288821 EK291523 EK296037 EK296321 EP09022 EP09115 EP09430 EP10014 EP12119 EP18251 FGH110D04 FGH111C05 IP15247 IP15347 IP15547 IP17684 IP17784 IP17984 LD38758 RE22433 RP004207657 SD08586 UUGC0430
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033504 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36084
Antibody Information
	polyclonal (Yamazaki and Nusse, 2002, Bharadwaj et al., 2013)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: rexin CG18408 (FlyBase, 1996-)
Source for database merge of
Additional comments	Source for identity of rexin CG18408 was sequence comparison (date:010707). (FlyBase, 1996-)
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) CAP was isolated in a yeast two-hybrid screen, using Axn as a bait. (Yamazaki and Nusse, 2002) Annotations CG18408, CG18409, CG3451 merged as CG18408 in release 3 of the genome annotation, April 2002.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136726 NM_136727 NM_136728 NM_165757 NM_165758 NM_165759 NM_165760 NM_165761 NM_165762 NM_206073 NM_001144164 NM_001144165 NM_001144166 NM_001144167 NM_001144168 NM_001144169 NM_001169639 NM_001259309 NM_001259310 NM_001259311 NM_001259312 NM_001273930 NM_001273931 RefSeq (Proteins) • NP_610570 NP_610571 NP_610572 NP_724910 NP_724911 NP_724912 NP_724913 NP_724914 NP_724915 NP_995795 NP_001137636 NP_001137637 NP_001137638 NP_001137639 NP_001137640 NP_001137641 NP_001163110 NP_001246238 NP_001246239 NP_001246240 NP_001246241 NP_001260859 NP_001260860 DDBJ / EMBL / GenBank • AAF58813 AAF58814 AAF58815 AAF58816 AAL29113 AAM68778 AAM68779 AAM68780 AAM68781 AAM68782 AAN71445 AAN71620 AAO24972 AAO39438 AAS64879 AB053478 AB053479 AB053480 AB053481 AB053482 ACL83090 ACL83091 ACL83092 ACL83093 ACL83094 ACL83095 ACZ94385 AFH07993 AFH07994 AFH07995 AFH07996 AGB93392 AGB93393 AI297346 AI532298 AW944151 AW944326 AY061565 BAB62017 BAB62018 BAB62019 BAB62020 BAB62021 BH011472 BH759203 BH840393 BI230372 BI231554 BI371458 BI624873 BT001690 BT001858 BT003217 BT003435 CL610202 CZ477917 CZ480353 CZ481743 CZ483961 CZ484600 CZ484601 Entrez Gene - A searchable database of RefSeq genes. • 36084 UniProtKB/TrEMBL • A1Z866 A1Z867 A1Z869 A1Z870 A1Z871 A1Z872 B7YZD8 B7YZD9 B7YZE0 Q7JR75 Q7K1M7 Q8IGB7 Q8IGN4 Q86P80 Q966U7 Q966U8 Q966U9 Q966V0 Q966V1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Neutrophil cytosol factor 2 p67phox (IPR000108) Src homology-3 domain (IPR001452) Sorbin-like (IPR003127) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • IP16877 LP11629 SD03761
Linkouts
	BioGRID - A database of protein and genetic interactions • 61904 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033504 DroID - A comprehensive database of gene and protein interactions. • FBgn0033504 DRSC - Results from RNAi screens. • FBgn0033504 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033504 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18408-RI FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033504 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36084 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36084 modMine - Data generated by the modENCODE project. • FBgn0033504 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • A1Z872
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	CAP (Bharadwaj et al., 2013, Buszczak et al., 2007, Nelson et al., 2005, Kaltenbach et al., 2007, Kallappagoudar et al., 2010, Strub et al., 2008, Firth and Baker, 2007, Serio et al., 2010, Wasbrough et al., 2010, Japanese National Institute of Genetics, 2012.5.21, Senthilan et al., 2012, Tunstall et al., 2012) cap (Zinzen et al., 2009) CAP/Vinexin (Avery et al., 2004) CG3451   CG18408 (Metta et al., 2006, Perkins et al., 2009, Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Strub et al., 2008, Cammarato et al., 2011) CG18409 (Borras et al., 2003, ) DCAP (Yamazaki and Yanagawa, 2003, Yamazaki and Nusse, 2002) Rexin (Knust and Bossinger, 2002) rexin (Giot et al., 2003, )
Name Synonym	CAP (Nelson et al., 2005, Kaltenbach et al., 2007, Cammarato et al., 2011) cap (Zinzen et al., 2009) Rexin/CAP (Girard et al., 2006)
Secondary FlyBase IDs
	FBgn0033503 FBgn0033505
References ( 49 )
Generate a list of	All references relating to this gene ( 49 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 9 ) Review  ( 1 ) Personal communication to FlyBase  ( 13 ) Abstract  ( 2 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 3 )
	Bharadwaj et al., 2013, Development 140(3): 627--638 Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. [FBrf0220383] Senthilan et al., 2012, Cell 150(5): 1042--1054 Drosophila auditory organ genes and genetic hearing defects. [FBrf0219321] Tunstall et al., 2012, PLoS ONE 7(4): e35641 A Screen for Genes Expressed in the Olfactory Organs of Drosophila melanogaster Identifies Genes Involved in Olfactory Behaviour. [FBrf0218110] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...