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Gene Dmel\CG8979

General Information
Symbol	Dmel\CG8979	Species	D. melanogaster
Name		Annotation symbol	CG8979
Feature type	protein_coding_gene	FlyBase ID	FBgn0033669
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	48D5-48D5	Sequence location	2R:7,854,848..7,857,591 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8979 (FBgn0033669). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: response to DNA damage stimulus. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Proteasome Inhibitor PI31. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult heart, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626981_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG8979. Gene sequence location is 2R:7854848..7857591.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Transcripts CG8979-RF CG8979-RD CG8979-RE Polypeptides CG8979-PD CG8979-PF CG8979-PE Clones RE31413 RE16863 EK243543 RE25796 101392 RE14824 Controlled Vocabulary Terms day 6 of adulthood day 5 of adulthood male day 7 of adulthood spermatozoon
FB2012_01	Sequence features BKN27597 HFA07306
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 48D5-48D5   Limits computationally determined from genome sequence between P{lacW}l(2)k06612k06612 and P{lacW}jebk05644
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8979 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.42
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8979-RA FBtr0088051  NM_136871   1137   270 CG8979-RB FBtr0088053  NM_165854   1113   270 CG8979-RC FBtr0088052  NM_165855   1222   270 CG8979-RD FBtr0310157     1089   270 CG8979-RE FBtr0310158     1200   270 CG8979-RF FBtr0310159     1170   270
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8979-PA   FBpp0087157   30.1   270   5.18     NP_610715   AAF58602 CG8979-PB   FBpp0087159   30.1   270   5.18     NP_725092   AAM68701 CG8979-PC   FBpp0087158   30.1   270   5.18     NP_725093   AAM68702 CG8979-PD   FBpp0301842   30.1   270   5.18       CG8979-PE   FBpp0301843   30.1   270   5.18       CG8979-PF   FBpp0301844   30.1   270   5.18
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Proteasome Inhibitor PI31 (IPR021625)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF58602   AE013599 AAM68701   AE013599 AAM68702   AI062169   AI062170   AI109860   AI259892   AI513094   AI517243   AI546699   AI944752   AI946119   AI947037   AY058250 AAL13479   BE975188   BF486743   BF498952   BF501235   BF502978   BI164427   BI170601   BI172368   BI173765   BI228300   BI235554   BI355949   BI361966   BI369246   BI483553   BI578231   BI578312   BI580534   BI622609   BI637369   BI639144   BI640943   BP551296   CA805953   CO292763   CO304062   EC064800   EC227070   EC247043   ES689965   ES689991   EV576860   EV577847   EV581978   GH748729   GH749211   GH749434   GH752561   GH753723   GH755263   GH759086   GH772023   GH775684   GH778221   GH781182   GH783540   GH793741   GH794138   GH799074   GH805248   GH809199   GH810732   GH812670   GH815500   GH819980   GH824683   GH825417   GH826152   GH828078   GH828102   GH829339   GH829962   GH835786   GH836382   GH842081   GH842344   GH847633   GH847673   GH857274   GH858619   GH871086   GH877602   GH878484   GH881161   GH886293   GH886663   GH886782   GH889071   GH889755   GH889903   GH892472   GH894262   GH899392   GH903581   GH904038   GH907486   GH909562   GH911064   GH911771   GH915991   GH918478   GH919418   GH921017   GH923155   GH923579   GH931731   GH932419   GH933760   GH935640   GH942772   GH948704   GH950126   GH964000   GH969413   GH970002   GH970430   GH971607   GH974426   GH974452   GH981634   GH982479
UniProtKB/Swiss-Prot	Q9V637
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033669    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033669 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033669 expression level Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day    11747 adult male 30day    12211 adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5793) embryo 02-04hr  (4810) embryo 04-06hr  (6092) embryo 06-08hr  (5023) embryo 08-10hr  (4957) embryo 10-12hr  (5721) embryo 12-14hr  (3667) embryo 14-16hr  (3980) embryo 16-18hr  (2868) embryo 18-20hr  (2321) embryo 20-22hr  (1660) embryo 22-24hr  (1766) larva L1  (1967) larva L2  (2329) larva L3 12hr old  (1574) larva L3 puffstage 1-2  (2767) larva L3 puffstage 3-6  (4535) larva L3 puffstage 7-9  (6191) white prepupae new  (5818) white prepupae 12hr  (5222) white prepupae 24hr  (6389) pupae 2d postWPP  (6548) pupae 3d postWPP  (6171) pupae 4d postWPP  (6468) adult male 01day  (8789) adult male 05day  (11747) adult male 30day  (12211) adult female 01day  (3665) adult female 05day  (4116) adult female 30day  (4206) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5793) embryo 02-04hr  (4810) embryo 04-06hr  (6092) embryo 06-08hr  (5023) embryo 08-10hr  (4957) embryo 10-12hr  (5721) embryo 12-14hr  (3667) embryo 14-16hr  (3980) embryo 16-18hr  (2868) embryo 18-20hr  (2321) embryo 20-22hr  (1660) embryo 22-24hr  (1766) larva L1  (1967) larva L2  (2329) larva L3 12hr old  (1574) larva L3 puffstage 1-2  (2767) larva L3 puffstage 3-6  (4535) larva L3 puffstage 7-9  (6191) white prepupae new  (5818) white prepupae 12hr  (5222) white prepupae 24hr  (6389) pupae 2d postWPP  (6548) pupae 3d postWPP  (6171) pupae 4d postWPP  (6468) adult male 01day  (8789) adult male 05day  (11747) adult male 30day  (12211) adult female 01day  (3665) adult female 05day  (4116) adult female 30day  (4206) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day  (11747) adult male 30day  (12211) adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day    11747 adult male 30day    12211 adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033669 expression level Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day    11747 adult male 30day    12211 adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5793) embryo 02-04hr  (4810) embryo 04-06hr  (6092) embryo 06-08hr  (5023) embryo 08-10hr  (4957) embryo 10-12hr  (5721) embryo 12-14hr  (3667) embryo 14-16hr  (3980) embryo 16-18hr  (2868) embryo 18-20hr  (2321) embryo 20-22hr  (1660) embryo 22-24hr  (1766) larva L1  (1967) larva L2  (2329) larva L3 12hr old  (1574) larva L3 puffstage 1-2  (2767) larva L3 puffstage 3-6  (4535) larva L3 puffstage 7-9  (6191) white prepupae new  (5818) white prepupae 12hr  (5222) white prepupae 24hr  (6389) pupae 2d postWPP  (6548) pupae 3d postWPP  (6171) pupae 4d postWPP  (6468) adult male 01day  (8789) adult male 05day  (11747) adult male 30day  (12211) adult female 01day  (3665) adult female 05day  (4116) adult female 30day  (4206) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5793) embryo 02-04hr  (4810) embryo 04-06hr  (6092) embryo 06-08hr  (5023) embryo 08-10hr  (4957) embryo 10-12hr  (5721) embryo 12-14hr  (3667) embryo 14-16hr  (3980) embryo 16-18hr  (2868) embryo 18-20hr  2321 embryo 20-22hr  1660 embryo 22-24hr  1766 larva L1  1967 larva L2  2329 larva L3 12hr old  1574 larva L3 puffstage 1-2  (2767) larva L3 puffstage 3-6  (4535) larva L3 puffstage 7-9  (6191) white prepupae new  (5818) white prepupae 12hr  (5222) white prepupae 24hr  (6389) pupae 2d postWPP  (6548) pupae 3d postWPP  (6171) pupae 4d postWPP  (6468) adult male 01day  (8789) adult male 05day  (11747) adult male 30day  (12211) adult female 01day  (3665) adult female 05day  (4116) adult female 30day  (4206) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day  11747 adult male 30day  12211 adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5793 embryo 02-04hr    4810 embryo 04-06hr    6092 embryo 06-08hr    5023 embryo 08-10hr    4957 embryo 10-12hr    5721 embryo 12-14hr    3667 embryo 14-16hr    3980 embryo 16-18hr    2868 embryo 18-20hr    2321 embryo 20-22hr    1660 embryo 22-24hr    1766 larva L1    1967 larva L2    2329 larva L3 12hr old    1574 larva L3 puffstage 1-2    2767 larva L3 puffstage 3-6    4535 larva L3 puffstage 7-9    6191 white prepupae new    5818 white prepupae 12hr    5222 white prepupae 24hr    6389 pupae 2d postWPP    6548 pupae 3d postWPP    6171 pupae 4d postWPP    6468 adult male 01day    8789 adult male 05day    11747 adult male 30day    12211 adult female 01day    3665 adult female 05day    4116 adult female 30day    4206 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033669    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033669 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult heart, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033669 expression level Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis    1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart  (642) Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis  (1046) Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis  1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis    1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033669 expression level Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis    1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart  642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis  (1046) Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis  1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    243.475 Larval Midgut    141 Larval Hindgut    166.2 Larval Malpighian Tubules    274.7 Larval Fat Body    269 Larval Salivary Gland    175.4 Larval Trachea    232.925 Larval Carcass    151.325 Adult Head    224.5 Adult Eye    453.775 Adult Brain    312.1 Adult Thoracic-Abdominal Ganglion    306.8 Adult Crop    267 Adult Midgut    149 Adult Hindgut    206.8 Adult Malpighian Tubules    204.1 Adult Fat Body    445.7 Adult Salivary Gland    215.8 Adult Heart    642 Adult VirginFemale Spermatheca    172.9 Adult InseminatedFemale Spermatheca    186.2 Adult Ovary    239.6 Adult Testis    1046 Adult Male Accessory Gland    292.5 Adult Carcass    413.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    224.5   NA  Eye    453.775   NA  Brain    312.1   243.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    306.8   NA  Crop    267   141  Midgut    149   166.2  Hindgut    206.8   274.7  Malpighian Tubules    204.1   269  Fat Body    445.7   175.4  Salivary Gland    215.8   NA  Heart    642   232.925  Trachea    NA   NA  VirginFemale Spermatheca    172.9   NA  InseminatedFemale Spermatheca    186.2   NA  Ovary    239.6   NA  Testis    1046   NA  Male Accessory Gland    292.5   151.325  Carcass    413.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033669 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8979-RC FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8979 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG8979GD13764 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG8979GD13764 visible, with Scer\GAL4pnr-MD237 CG8979GD13764 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG8979GD13764 trichogen cell, with Scer\GAL4pnr-MD237 CG8979GD13764
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG8979 Class Mutagen Stocks Known lesion CG8979G7971 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8979 Class Mutagen Stocks Known lesion CG8979GD13764 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG8979KK107597 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13764} NA P{KK107597} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG03360 NA insertion of mobile activating element P{EP}CG8979G7971 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a cellular component or molecular function term for this gene. (Based on a review of available data on: 2010-07-22)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
response to DNA damage stimulus inferred from mutant phenotype (Ravi et al., 2009)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8979 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62061 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033669 DroID - A comprehensive database of gene and protein interactions. • FBgn0033669 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36277
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11798 Dere\GG22619 Dgri\GH20402 Dmoj\GI19589 Dper\GL10241 Dpse\GA21450 Dsec\GM20399 Dsim\GD25873 Dvir\GJ18358 Dwil\GK22249 Dyak\GE13488
Curated drosophilid orthologs	Dpse\GA21450
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001422-PA Aedes aegypti (mosquito) AGAP007418-PA Anopheles gambiae (mosquito) XP_393166.2 Apis mellifera (honey bee) XP_001952651.1 Acyrthosiphon pisum (pea aphid) 37577 Batrachochytrium dendrobatidis (chytrid fungus) 224758 Branchiostoma floridae (lancelet) 224884 Branchiostoma floridae (lancelet) BGIBMGA003583-PA Bombyx mori (silk worm) ENSBTAP00000024505 Bos taurus (bovine) ENSCAFP00000010190 Canis familiaris (dog) CPIJ000276 Culex pipens (mosquito) ENSCPOP00000012399 Cavia porcellus (guinea pig) 176567 Capitella spl (polychaete worm) DDB0232963 Dictyostelium discoideum (amoeba) 302186 Daphnia pulex (daphnia) ENSDARP00000093216 Danio rerio (zebra fish) ENSECAP00000021490 Equus caballus (horse) ENSGACP00000000034 Gymnopilus aculeatus (mushroom) ENSGALP00000000338 Gallus gallus (chicken) 185589 Hypsipyla robusta (cedar shoot borer) ENSP00000327704 Homo sapiens (human) 110935 Lottia gigantea (owl limpet) ENSMODP00000024375 Monodelphis domestica (gray opossum) ENSMMUP00000006261 Macaca mulatta (rhesus monkey) ENSMUSP00000041184 Mus musculus (house mouse) 245135 Nematostella vectensis (starlet anemone) XP_001602913.1 Nasonia vitripennis (wasp) PHUM011590-PA Pediculus humanus (human body louse) ENSPPYP00000012129 Pongo pygmaeus (orangutan) 79776 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000022517 Pan troglodytes (chimpanzee) ENSRNOP00000038926 Rattus norvegicus (norway rat) Smp_066340.2 Schistosoma mansoni (trematode parasite) XP_782862.1 Strongylocentrotus purpuratus (purple sea urchin) 58401 Trichoplax adhaerens (metazoa) 3686.m00092 Tetrahymena thermophila (ciliate protozoa) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15854 NV16505 LH24510 ISCW020292 FBgn0231157 FBgn0224234 FBgn0205517 FBgn0197153 FBgn0175282 JGI_V11_302186 JGI_V11_119605 FBgn0081437 FBgn0147851 FBgn0142326 FBgn0127865 FBgn0119820 FBgn0114790 FBgn0088838 CPIJ000276 BGIBMGA003583 ACYPI27321 ACYPI000244 GB11336 AGAP007418 AAEL001422 PHUM616880 GLEAN_07686
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	28491 y1 w*; P{EP}CG8979G7971/CyO
VDRC	v105476 P{KK107597}VIE-260B v28858 w1118; P{GD13764}v28858 v28860 w1118; P{GD13764}v28860/TM3
Genomic Clones ( 1 )
	BACR14L19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 119 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH01278
Other clones	DPiM_GH01278
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT13441 AT16506 AT18854 AT21258 GH01277 GH09242 GH27918 LP03412 RE04095 RE12117 RE14824 RE16863 RE25796 RE31413 RE37017 RE46408 RE55368 RE66464 RE72074 RE72165 RE74742 RH54510 SD10439 SD19363 SD21607 SD23981
Other clones	72214 101392 164886 bs05b01 bs21b04 bs34c12 bs39f02 Dmel_dig_000743_0648_0435 Dmel_dig_003048_0588_1664 Dmel_dig_003868_0611_3127 EK200920 EK243543 ESG0120b.B21_H06 FGM212B01 RP003008351 RP003016425 RP003036338 RP003048800 RP003049011 RP003066774 RP003067417 RP003069181 RP003078191 RP003093020 RP003098175 RP003107602 RP003126529 RP003128486 RP003143555 RP003161756 RP003163113 RP003168362 RP003171018 RP003174703 RP003186291 RP003212460 RP003226594 RP003228974 RP003246634 RP003272200 RP003275781 RP003282885 RP003285015 RP003286777 RP003297605 RP003300806 RP003307813 RP003318776 RP003322165 RP003324877 RP003336594 RP003340633 RP003342504 RP003348092 RP003351411 RP003359013 RP003383086 RP003423964 RP003452521 RP003465952 RP003478021 RP003486939 RP003510522 RP003514169 RP003518602 RP003525009 RP003540015 RP003540809 RP003551873 RP003552707 RP003556760 RP003558261 RP003562587 RP003601898 RP003617109 RP003627332 RP003628655 RP003633284 RP003644490 RP004176524 RP004194516 RP004220476 RP004229363 RP004257283 RP004362668 RP004363479 RP004410020 RP004427003 RP004433512 RP004441724 RP004509959
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033669 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36277
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136871 NM_165854 NM_165855 RefSeq (Proteins) • NP_610715 NP_725092 NP_725093 DDBJ / EMBL / GenBank • AAF58602 AAL13479 AAM68701 AAM68702 AI062170 AI259892 AI513094 AI546699 AI944752 AI946119 AI947037 AY058250 Entrez Gene - A searchable database of RefSeq genes. • 36277 UniProtKB/Swiss-Prot • Q9V637
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Proteasome Inhibitor PI31 (IPR021625)
Linkouts
	BioGRID - A database of protein and genetic interactions • 62061 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033669 DroID - A comprehensive database of gene and protein interactions. • FBgn0033669 DRSC - Results from RNAi screens. • FBgn0033669 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033669 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8979-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033669 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36277 InParanoid A subset of ortholog calls from InParanoid. • AAEL001422-PA Aedes aegypti (mosquito) AGAP007418-PA Anopheles gambiae (mosquito) XP_393166.2 Apis mellifera (honey bee) XP_001952651.1 Acyrthosiphon pisum (pea aphid) 37577 Batrachochytrium dendrobatidis (chytrid fungus) 224758 Branchiostoma floridae (lancelet) 224884 Branchiostoma floridae (lancelet) BGIBMGA003583-PA Bombyx mori (silk worm) ENSBTAP00000024505 Bos taurus (bovine) ENSCAFP00000010190 Canis familiaris (dog) CPIJ000276 Culex pipens (mosquito) ENSCPOP00000012399 Cavia porcellus (guinea pig) 176567 Capitella spl (polychaete worm) DDB0232963 Dictyostelium discoideum (amoeba) 302186 Daphnia pulex (daphnia) ENSDARP00000093216 Danio rerio (zebra fish) ENSECAP00000021490 Equus caballus (horse) ENSGACP00000000034 Gymnopilus aculeatus (mushroom) ENSGALP00000000338 Gallus gallus (chicken) 185589 Hypsipyla robusta (cedar shoot borer) ENSP00000327704 Homo sapiens (human) 110935 Lottia gigantea (owl limpet) ENSMODP00000024375 Monodelphis domestica (gray opossum) ENSMMUP00000006261 Macaca mulatta (rhesus monkey) ENSMUSP00000041184 Mus musculus (house mouse) 245135 Nematostella vectensis (starlet anemone) XP_001602913.1 Nasonia vitripennis (wasp) PHUM011590-PA Pediculus humanus (human body louse) ENSPPYP00000012129 Pongo pygmaeus (orangutan) 79776 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000022517 Pan troglodytes (chimpanzee) ENSRNOP00000038926 Rattus norvegicus (norway rat) Smp_066340.2 Schistosoma mansoni (trematode parasite) XP_782862.1 Strongylocentrotus purpuratus (purple sea urchin) 58401 Trichoplax adhaerens (metazoa) 3686.m00092 Tetrahymena thermophila (ciliate protozoa) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36277 modMine - Data generated by the modENCODE project. • FBgn0033669 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15854 NV16505 LH24510 ISCW020292 FBgn0231157 FBgn0224234 FBgn0205517 FBgn0197153 FBgn0175282 JGI_V11_302186 JGI_V11_119605 FBgn0081437 FBgn0147851 FBgn0142326 FBgn0127865 FBgn0119820 FBgn0114790 FBgn0088838 CPIJ000276 BGIBMGA003583 ACYPI27321 ACYPI000244 GB11336 AGAP007418 AAEL001422 PHUM616880 GLEAN_07686
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	8979 (Ravi et al., 2009) cg8979 (Herold et al., 2003) CG8979 (Keleman et al., 2009.8.5, Wasbrough et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Ravi et al., 2009, PLoS Genet. 5(6): e1000527 A network of conserved damage survival pathways revealed by a genomic RNAi screen. [FBrf0208272] Herold et al., 2003, EMBO J. 22(10): 2472--2483 Genome-wide analysis of nuclear mRNA export pathways in Drosophila. [FBrf0158900]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wasbrough et al., 2010, J. Proteomics 73(11): Supplemental Table 1. Mass spectrometry data. [FBrf0213252] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2009.8.20, BDGP_2009_0825.GenExel.xml BDGP_2009_0825.GenExel.xml [FBrf0208536] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Anonymous, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126650]
Protein sequence record	Swiss-Prot Project Members, 2001.8.20, UniProtKB: Q9V637 Putative proteasome inhibitor. [FBrf0151077]