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Gene Dmel\RpS11

General Information
Symbol	Dmel\RpS11	Species	D. melanogaster
Name	Ribosomal protein S11	Annotation symbol	CG8857
Feature type	protein_coding_gene	FlyBase ID	FBgn0033699
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	S11
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	48E8-48E9	Sequence location	2R:8,086,529..8,088,320 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein S11 is referred to in FlyBase by the symbol Dmel\RpS11 (CG8857, FBgn0033699). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization; neurogenesis. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Nucleic acid-binding, OB-fold; Ribosomal protein S17; Ribosomal protein S17, archaeal; Ribosomal protein S17, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Gene sequence location is 2R:8086529..8088320.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 48E8-48E9   Limits computationally determined from genome sequence between P{PZ}SmD302833 and P{PZ}Cam03909
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpS11 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpS11-RB FBtr0088006  NM_165869   569   154 RpS11-RC FBtr0088007  NM_165868   738   155
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpS11-PB   FBpp0087114   18.1   154   11.70     NP_725115   AAM71029 RpS11-PC   FBpp0087115   18.1   155   11.56     NP_725114   AAM71028
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S17 (IPR000266) Nucleic acid-binding, OB-fold (IPR012340) Ribosomal protein S17, conserved site (IPR019979) Ribosomal protein S17, archaeal (IPR019978)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264285   AA390668   AA433211   AA536266   AA695524   AA696068   AA735669   AA735677   AA735854   AA736042   AA802541   AA802659   AA803003   AA803226   AA803530   AA803893   AA803908   AA978402   AE013599 AAM71028   AE013599 AAM71029   AI113925   AI114063   AI114096   AI114143   AI238277   AI260213   AI261016   AI261095   AI292955   AI293740   AI294798   AI387372   AI387976   AI388630   AI389123   AI403011   AI403364   AI403699   AI404011   AI405152   AI405195   AI405662   AI455832   AI517644   AI533663   AI544232   AI546430   AY231785   AY232057   BG632594   BG632651   BG633092   BG633096   BG634216   BG635518   BG636222   BG636593   BG636681   BG636989   BG637428   BG638504   BG639555   BG639628   BG640085   BG640426   BG640435   BG640735   BG640996   BG641300   BI141835   BI142061   BI163103   BI163158   BI165252   BI167049   BI167455   BI168296   BI168911   BI169110   BI169542   BI170135   BI170766   BI213847   BI215037   BI215423   BI228633   BI228814   BI230221   BI230632   BI232217   BI232540   BI233173   BI236772   BI239159   BI239416   BI241278   BI241531   BI242313   BI243873   BI243905   BI351691   BI351980   BI352152   BI352200   BI352298   BI352931   BI352997   BI353322   BI353437   BI353687   BI354026   BI354132   BI354525   BI354653   BI354769   BI355062   BI355180   BI355275   BI355313   BI355351   BI355770   BI356340   BI358042   BI362757   BI363775   BI364365   BI365340   BI365951   BI366352   BI367694   BI368206   BI369566   BI370666   BI370947   BI482333   BI486323   BI486579   BI564922   BI565317   BI565403   BI570684   BI570737   BI572278   BI572287   BI573113   BI573123   BI575603   BI578225   BI581156   BI582267   BI582322   BI582388   BI582521   BI582593   BI582617   BI583036   BI583624   BI588938   BI589001   BI590721   BI591788   BI593513   BI605772   BI607511   BI608110   BI610290   BI611958   BI614817   BI617453   BI618717   BI619614   BI619973   BI620233   BI620768   BI622419   BI626064   BI627350   BI627781   BI628303   BI629116   BI632980   BI633218   BI633242   BI633370   BI633631   BI633682   BI634879   BI635309   BI635650   BI635840   BI636000   BI636091   BI636108   BI636109   BI636382   BI636510   BI637257   BI637818   BI637822   BI638092   BI638882   BI639055   BI639537   BI639658   BI640029   BI640262   BI640354   BI640383   BI640433   BI640479   BI641090   BI641136   BI641221   BI641374   BI641453   BI641664   BI641759   BP541395   BP541578   BP543054   BP543112   BP543538   BP543568   BP543991   BP544046   BP544060   BP544269   BP545896   BP546722   BP546918   BP546922   BP547318   BP547529   BP548138   BP548215   BP548412   BP548978   BP549889   BP550023   BP550791   BP551177   BP551690   BP551754   BP551843   BP553949   BP554129   BP554648   BP555423   BP556682   BP557137   BP557182   BP557817   BP559242   BP560172   BP560329   BP560376   BQ103198   BQ103557   BT088759   BT088761   BT088762   CA803780   CA804583   CA805078   CA805248   CA805696   CK657016   CK657965   CK658306   CK658857   CK660866   CK661134   CO152777   CO153497   CO153694   CO153817   CO154646   CO155241   CO155340   CO155680   CO156053   CO180771   CO181013   CO181135   CO181521   CO181633   CO181679   CO181689   CO181749   CO182054   CO182106   CO182195   CO182929   CO183265   CO183342   CO184733   CO191152   CO191238   CO192296   CO192714   CO192803   CO194272   CO195154   CO195330   CO195403   CO195567   CO196672   CO266230   CO273536   CO274400   CO281450   CO285504   CO287417   CO296329   CO299122   CO302825   CO306690   CO311086   CO318075   CO321411   CO329779   CO336011   CO336126   CO336522   CO336842   CO337024   CO337215   EC052777   EC060362   EC060501   EC202167   EC203351   EC209445   EC211774   EC222341   EC223057   EC223441   EC228783   EC243941   EC250054   EC250713   EC261088   EC261177   EC261392   EC261617   EC261729   EC262728   EC262738   EC262956   EC265148   EC266005   EC266090   EC266498   EC266919   EL872902   EL878963   EL881918   ES690026   EV574783   EV575082   EV575199   EV575284   EV575294   EV575305   EV575370   EV575644   EV575876   EV576194   EV576489   EV576567   EV577369   EV577613   EV577638   EV577715   EV577737   EV578040   EV578362   EV579350   EV579685   EV579735   EV579829   EV580085   EV580453   EV580745   EV581136   EV581205   EV581509   EV581681   EV581792   EV581930   EV582521   EV582548   EV582946   EV582951   EV583100   EV583106   EV583171   EV583754   EV584126   EV584376   EV584438   EV584609   EV584810   EV585040   EV585149   EV585924   EV585989   EV586045   EV586180   EV586640   EV587123   EV587163   EV587488   EV587786   EV588459   EV589204   EV590055   EV590633   EV590675   EV591028   EV591081   EV592827   EV593045   EV593237   EV593808   EV594114   EV594211   EV594842   EV594949   EV597508   EV597647   EV598121   EV598483   EV598538   EV599158   EV599705   GH942647   GH950158   GH950746   GH952817   GH955042   GH961397   GH963142   GH966402   GH966431   GH966604   GH967219   GH969684   GH970842   GH971587   GH972636   GH972959   GH974153   GH979317   GH982468   GH984790
UniProtKB/Swiss-Prot	Q0E9B6
UniProtKB/TrEMBL	A1Z8U9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    357 central nervous system, larvae L3    283 central nervous system, pupae P8    151 head, virgin 1-day female    154 head, virgin 4-day female    211 head, virgin 20-day female    291 head, mated 1-day female    131 head, mated 4-day female    223 head, mated 20-day female    241 head, mated 1-day male    135 head, mated 4-day male    142 head, mated 20-day male    216 salivary gland, larvae L3 wandering    168 salivary gland, white prepupae    354 digestive system, larvae L3 wandering    249 digestive system, 1-day adult    229 digestive system, 4-day adult    190 digestive system, 20-day adult    194 fat body, larvae L3 wandering    132 fat body, white prepupae    136 fat body, pupae P8    257 carcass, larvae L3 wandering    292 carcass, 1-day adult    153 carcass, 4-day adult    186 carcass, 20-day adult    190 ovary, virgin 4-day female    324 ovary, mated 4-day female    299 testis, mated 4-day male    183 accessory gland, mated 4-day male    213 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (357) central nervous system, larvae L3  (283) central nervous system, pupae P8  (151) head, virgin 1-day female  (154) head, virgin 4-day female  (211) head, virgin 20-day female  (291) head, mated 1-day female  (131) head, mated 4-day female  (223) head, mated 20-day female  (241) head, mated 1-day male  (135) head, mated 4-day male  (142) head, mated 20-day male  (216) salivary gland, larvae L3 wandering  (168) salivary gland, white prepupae  (354) digestive system, larvae L3 wandering  (249) digestive system, 1-day adult  (229) digestive system, 4-day adult  (190) digestive system, 20-day adult  (194) fat body, larvae L3 wandering  (132) fat body, white prepupae  (136) fat body, pupae P8  (257) carcass, larvae L3 wandering  (292) carcass, 1-day adult  (153) carcass, 4-day adult  (186) carcass, 20-day adult  (190) ovary, virgin 4-day female  (324) ovary, mated 4-day female  (299) testis, mated 4-day male  (183) accessory gland, mated 4-day male  (213) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (357) central nervous system, larvae L3  (283) central nervous system, pupae P8  (151) head, virgin 1-day female  (154) head, virgin 4-day female  (211) head, virgin 20-day female  (291) head, mated 1-day female  (131) head, mated 4-day female  (223) head, mated 20-day female  (241) head, mated 1-day male  (135) head, mated 4-day male  (142) head, mated 20-day male  (216) salivary gland, larvae L3 wandering  (168) salivary gland, white prepupae  (354) digestive system, larvae L3 wandering  (249) digestive system, 1-day adult  (229) digestive system, 4-day adult  (190) digestive system, 20-day adult  (194) fat body, larvae L3 wandering  (132) fat body, white prepupae  (136) fat body, pupae P8  (257) carcass, larvae L3 wandering  (292) carcass, 1-day adult  (153) carcass, 4-day adult  (186) carcass, 20-day adult  (190) ovary, virgin 4-day female  (324) ovary, mated 4-day female  (299) testis, mated 4-day male  (183) accessory gland, mated 4-day male  (213) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    357 central nervous system, larvae L3    283 central nervous system, pupae P8    151 head, virgin 1-day female    154 head, virgin 4-day female    211 head, virgin 20-day female    291 head, mated 1-day female    131 head, mated 4-day female    223 head, mated 20-day female    241 head, mated 1-day male    135 head, mated 4-day male    142 head, mated 20-day male    216 salivary gland, larvae L3 wandering    168 salivary gland, white prepupae    354 digestive system, larvae L3 wandering    249 digestive system, 1-day adult    229 digestive system, 4-day adult    190 digestive system, 20-day adult    194 fat body, larvae L3 wandering    132 fat body, white prepupae    136 fat body, pupae P8    257 carcass, larvae L3 wandering    292 carcass, 1-day adult    153 carcass, 4-day adult    186 carcass, 20-day adult    190 ovary, virgin 4-day female    324 ovary, mated 4-day female    299 testis, mated 4-day male    183 accessory gland, mated 4-day male    213 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    357 central nervous system, larvae L3    283 central nervous system, pupae P8    151 head, virgin 1-day female    154 head, virgin 4-day female    211 head, virgin 20-day female    291 head, mated 1-day female    131 head, mated 4-day female    223 head, mated 20-day female    241 head, mated 1-day male    135 head, mated 4-day male    142 head, mated 20-day male    216 salivary gland, larvae L3 wandering    168 salivary gland, white prepupae    354 digestive system, larvae L3 wandering    249 digestive system, 1-day adult    229 digestive system, 4-day adult    190 digestive system, 20-day adult    194 fat body, larvae L3 wandering    132 fat body, white prepupae    136 fat body, pupae P8    257 carcass, larvae L3 wandering    292 carcass, 1-day adult    153 carcass, 4-day adult    186 carcass, 20-day adult    190 ovary, virgin 4-day female    324 ovary, mated 4-day female    299 testis, mated 4-day male    183 accessory gland, mated 4-day male    213 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (357) central nervous system, larvae L3  (283) central nervous system, pupae P8  (151) head, virgin 1-day female  (154) head, virgin 4-day female  (211) head, virgin 20-day female  (291) head, mated 1-day female  (131) head, mated 4-day female  (223) head, mated 20-day female  (241) head, mated 1-day male  (135) head, mated 4-day male  (142) head, mated 20-day male  (216) salivary gland, larvae L3 wandering  (168) salivary gland, white prepupae  (354) digestive system, larvae L3 wandering  (249) digestive system, 1-day adult  (229) digestive system, 4-day adult  (190) digestive system, 20-day adult  (194) fat body, larvae L3 wandering  (132) fat body, white prepupae  (136) fat body, pupae P8  (257) carcass, larvae L3 wandering  (292) carcass, 1-day adult  (153) carcass, 4-day adult  (186) carcass, 20-day adult  (190) ovary, virgin 4-day female  (324) ovary, mated 4-day female  (299) testis, mated 4-day male  (183) accessory gland, mated 4-day male  (213) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (357) central nervous system, larvae L3  (283) central nervous system, pupae P8  (151) head, virgin 1-day female  (154) head, virgin 4-day female  (211) head, virgin 20-day female  (291) head, mated 1-day female  131 head, mated 4-day female  (223) head, mated 20-day female  (241) head, mated 1-day male  135 head, mated 4-day male  142 head, mated 20-day male  (216) salivary gland, larvae L3 wandering  (168) salivary gland, white prepupae  (354) digestive system, larvae L3 wandering  (249) digestive system, 1-day adult  (229) digestive system, 4-day adult  (190) digestive system, 20-day adult  (194) fat body, larvae L3 wandering  132 fat body, white prepupae  136 fat body, pupae P8  (257) carcass, larvae L3 wandering  (292) carcass, 1-day adult  (153) carcass, 4-day adult  (186) carcass, 20-day adult  (190) ovary, virgin 4-day female  (324) ovary, mated 4-day female  (299) testis, mated 4-day male  (183) accessory gland, mated 4-day male  (213) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    357 central nervous system, larvae L3    283 central nervous system, pupae P8    151 head, virgin 1-day female    154 head, virgin 4-day female    211 head, virgin 20-day female    291 head, mated 1-day female    131 head, mated 4-day female    223 head, mated 20-day female    241 head, mated 1-day male    135 head, mated 4-day male    142 head, mated 20-day male    216 salivary gland, larvae L3 wandering    168 salivary gland, white prepupae    354 digestive system, larvae L3 wandering    249 digestive system, 1-day adult    229 digestive system, 4-day adult    190 digestive system, 20-day adult    194 fat body, larvae L3 wandering    132 fat body, white prepupae    136 fat body, pupae P8    257 carcass, larvae L3 wandering    292 carcass, 1-day adult    153 carcass, 4-day adult    186 carcass, 20-day adult    190 ovary, virgin 4-day female    324 ovary, mated 4-day female    299 testis, mated 4-day male    183 accessory gland, mated 4-day male    213 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1691 embryo 02-04hr    2565 embryo 04-06hr    2652 embryo 06-08hr    2714 embryo 08-10hr    3166 embryo 10-12hr    3874 embryo 12-14hr    2389 embryo 14-16hr    3287 embryo 16-18hr    2566 embryo 18-20hr    2512 embryo 20-22hr    2404 embryo 22-24hr    2218 larva L1    3257 larva L2    2484 larva L3 12hr old    2053 larva L3 puffstage 1-2    1716 larva L3 puffstage 3-6    1550 larva L3 puffstage 7-9    1677 white prepupae new    1483 white prepupae 12hr    1431 white prepupae 24hr    1354 pupae 2d postWPP    1236 pupae 3d postWPP    1046 pupae 4d postWPP    1336 adult male 01day    781 adult male 05day    760 adult male 30day    1061 adult female 01day    2297 adult female 05day    1758 adult female 30day    1895 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1691) embryo 02-04hr  (2565) embryo 04-06hr  (2652) embryo 06-08hr  (2714) embryo 08-10hr  (3166) embryo 10-12hr  (3874) embryo 12-14hr  (2389) embryo 14-16hr  (3287) embryo 16-18hr  (2566) embryo 18-20hr  (2512) embryo 20-22hr  (2404) embryo 22-24hr  (2218) larva L1  (3257) larva L2  (2484) larva L3 12hr old  (2053) larva L3 puffstage 1-2  (1716) larva L3 puffstage 3-6  (1550) larva L3 puffstage 7-9  (1677) white prepupae new  (1483) white prepupae 12hr  (1431) white prepupae 24hr  (1354) pupae 2d postWPP  (1236) pupae 3d postWPP  (1046) pupae 4d postWPP  (1336) adult male 01day  (781) adult male 05day  (760) adult male 30day  (1061) adult female 01day  (2297) adult female 05day  (1758) adult female 30day  (1895) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1691) embryo 02-04hr  (2565) embryo 04-06hr  (2652) embryo 06-08hr  (2714) embryo 08-10hr  (3166) embryo 10-12hr  (3874) embryo 12-14hr  (2389) embryo 14-16hr  (3287) embryo 16-18hr  (2566) embryo 18-20hr  (2512) embryo 20-22hr  (2404) embryo 22-24hr  (2218) larva L1  (3257) larva L2  (2484) larva L3 12hr old  (2053) larva L3 puffstage 1-2  (1716) larva L3 puffstage 3-6  (1550) larva L3 puffstage 7-9  (1677) white prepupae new  (1483) white prepupae 12hr  (1431) white prepupae 24hr  (1354) pupae 2d postWPP  (1236) pupae 3d postWPP  (1046) pupae 4d postWPP  (1336) adult male 01day  (781) adult male 05day  (760) adult male 30day  (1061) adult female 01day  (2297) adult female 05day  (1758) adult female 30day  (1895) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1691 embryo 02-04hr    2565 embryo 04-06hr    2652 embryo 06-08hr    2714 embryo 08-10hr    3166 embryo 10-12hr    3874 embryo 12-14hr    2389 embryo 14-16hr    3287 embryo 16-18hr    2566 embryo 18-20hr    2512 embryo 20-22hr    2404 embryo 22-24hr    2218 larva L1    3257 larva L2    2484 larva L3 12hr old    2053 larva L3 puffstage 1-2    1716 larva L3 puffstage 3-6    1550 larva L3 puffstage 7-9    1677 white prepupae new    1483 white prepupae 12hr    1431 white prepupae 24hr    1354 pupae 2d postWPP    1236 pupae 3d postWPP    1046 pupae 4d postWPP    1336 adult male 01day    781 adult male 05day    760 adult male 30day    1061 adult female 01day    2297 adult female 05day    1758 adult female 30day    1895 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1691 embryo 02-04hr    2565 embryo 04-06hr    2652 embryo 06-08hr    2714 embryo 08-10hr    3166 embryo 10-12hr    3874 embryo 12-14hr    2389 embryo 14-16hr    3287 embryo 16-18hr    2566 embryo 18-20hr    2512 embryo 20-22hr    2404 embryo 22-24hr    2218 larva L1    3257 larva L2    2484 larva L3 12hr old    2053 larva L3 puffstage 1-2    1716 larva L3 puffstage 3-6    1550 larva L3 puffstage 7-9    1677 white prepupae new    1483 white prepupae 12hr    1431 white prepupae 24hr    1354 pupae 2d postWPP    1236 pupae 3d postWPP    1046 pupae 4d postWPP    1336 adult male 01day    781 adult male 05day    760 adult male 30day    1061 adult female 01day    2297 adult female 05day    1758 adult female 30day    1895 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1691) embryo 02-04hr  (2565) embryo 04-06hr  (2652) embryo 06-08hr  (2714) embryo 08-10hr  (3166) embryo 10-12hr  (3874) embryo 12-14hr  (2389) embryo 14-16hr  (3287) embryo 16-18hr  (2566) embryo 18-20hr  (2512) embryo 20-22hr  (2404) embryo 22-24hr  (2218) larva L1  (3257) larva L2  (2484) larva L3 12hr old  (2053) larva L3 puffstage 1-2  (1716) larva L3 puffstage 3-6  (1550) larva L3 puffstage 7-9  (1677) white prepupae new  (1483) white prepupae 12hr  (1431) white prepupae 24hr  (1354) pupae 2d postWPP  (1236) pupae 3d postWPP  (1046) pupae 4d postWPP  (1336) adult male 01day  (781) adult male 05day  (760) adult male 30day  (1061) adult female 01day  (2297) adult female 05day  (1758) adult female 30day  (1895) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1691) embryo 02-04hr  (2565) embryo 04-06hr  (2652) embryo 06-08hr  (2714) embryo 08-10hr  (3166) embryo 10-12hr  (3874) embryo 12-14hr  (2389) embryo 14-16hr  (3287) embryo 16-18hr  (2566) embryo 18-20hr  (2512) embryo 20-22hr  (2404) embryo 22-24hr  (2218) larva L1  (3257) larva L2  (2484) larva L3 12hr old  (2053) larva L3 puffstage 1-2  (1716) larva L3 puffstage 3-6  (1550) larva L3 puffstage 7-9  (1677) white prepupae new  (1483) white prepupae 12hr  (1431) white prepupae 24hr  (1354) pupae 2d postWPP  (1236) pupae 3d postWPP  (1046) pupae 4d postWPP  (1336) adult male 01day  (781) adult male 05day  (760) adult male 30day  (1061) adult female 01day  (2297) adult female 05day  (1758) adult female 30day  (1895) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1691 embryo 02-04hr    2565 embryo 04-06hr    2652 embryo 06-08hr    2714 embryo 08-10hr    3166 embryo 10-12hr    3874 embryo 12-14hr    2389 embryo 14-16hr    3287 embryo 16-18hr    2566 embryo 18-20hr    2512 embryo 20-22hr    2404 embryo 22-24hr    2218 larva L1    3257 larva L2    2484 larva L3 12hr old    2053 larva L3 puffstage 1-2    1716 larva L3 puffstage 3-6    1550 larva L3 puffstage 7-9    1677 white prepupae new    1483 white prepupae 12hr    1431 white prepupae 24hr    1354 pupae 2d postWPP    1236 pupae 3d postWPP    1046 pupae 4d postWPP    1336 adult male 01day    781 adult male 05day    760 adult male 30day    1061 adult female 01day    2297 adult female 05day    1758 adult female 30day    1895 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    961 Schneider line 2 Sg4    562 embryonic 1182-4H    501 embryonic GM2    427 embryonic Kc167    462 embryonic S1    336 embryonic S3    544 leg disc CME L1    429 wing disc CME-W2    571 wing disc ML-DmD8    642 wing disc ML-DmD9    497 wing disc ML-DmD16-c3    314 wing disc ML-DmD21    927 wing disc ML-DmD32    306 haltere disc ML-DmD17-c3    366 eye-antennal disc ML-DmD11    582 antennal disc ML-DmD20-c5    690 mixed discs ML-DmD4-c1    479 CNS ML-DmBG1-c1    481 CNS ML-DmBG2-c2    1135 tumorous blood cells mbn2    896 ovary fGS/OSS    401 ovary OSC    293 ovary OSS    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (961) Schneider line 2 Sg4  (562) embryonic 1182-4H  (501) embryonic GM2  (427) embryonic Kc167  (462) embryonic S1  (336) embryonic S3  (544) leg disc CME L1  (429) wing disc CME-W2  (571) wing disc ML-DmD8  (642) wing disc ML-DmD9  (497) wing disc ML-DmD16-c3  (314) wing disc ML-DmD21  (927) wing disc ML-DmD32  (306) haltere disc ML-DmD17-c3  (366) eye-antennal disc ML-DmD11  (582) antennal disc ML-DmD20-c5  (690) mixed discs ML-DmD4-c1  (479) CNS ML-DmBG1-c1  (481) CNS ML-DmBG2-c2  (1135) tumorous blood cells mbn2  (896) ovary fGS/OSS  (401) ovary OSC  (293) ovary OSS  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (961) Schneider line 2 Sg4  (562) embryonic 1182-4H  (501) embryonic GM2  (427) embryonic Kc167  (462) embryonic S1  (336) embryonic S3  (544) leg disc CME L1  (429) wing disc CME-W2  (571) wing disc ML-DmD8  (642) wing disc ML-DmD9  (497) wing disc ML-DmD16-c3  (314) wing disc ML-DmD21  (927) wing disc ML-DmD32  (306) haltere disc ML-DmD17-c3  (366) eye-antennal disc ML-DmD11  (582) antennal disc ML-DmD20-c5  (690) mixed discs ML-DmD4-c1  (479) CNS ML-DmBG1-c1  (481) CNS ML-DmBG2-c2  (1135) tumorous blood cells mbn2  (896) ovary fGS/OSS  (401) ovary OSC  (293) ovary OSS  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    961 Schneider line 2 Sg4    562 embryonic 1182-4H    501 embryonic GM2    427 embryonic Kc167    462 embryonic S1    336 embryonic S3    544 leg disc CME L1    429 wing disc CME-W2    571 wing disc ML-DmD8    642 wing disc ML-DmD9    497 wing disc ML-DmD16-c3    314 wing disc ML-DmD21    927 wing disc ML-DmD32    306 haltere disc ML-DmD17-c3    366 eye-antennal disc ML-DmD11    582 antennal disc ML-DmD20-c5    690 mixed discs ML-DmD4-c1    479 CNS ML-DmBG1-c1    481 CNS ML-DmBG2-c2    1135 tumorous blood cells mbn2    896 ovary fGS/OSS    401 ovary OSC    293 ovary OSS    158 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    961 Schneider line 2 Sg4    562 embryonic 1182-4H    501 embryonic GM2    427 embryonic Kc167    462 embryonic S1    336 embryonic S3    544 leg disc CME L1    429 wing disc CME-W2    571 wing disc ML-DmD8    642 wing disc ML-DmD9    497 wing disc ML-DmD16-c3    314 wing disc ML-DmD21    927 wing disc ML-DmD32    306 haltere disc ML-DmD17-c3    366 eye-antennal disc ML-DmD11    582 antennal disc ML-DmD20-c5    690 mixed discs ML-DmD4-c1    479 CNS ML-DmBG1-c1    481 CNS ML-DmBG2-c2    1135 tumorous blood cells mbn2    896 ovary fGS/OSS    401 ovary OSC    293 ovary OSS    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (961) Schneider line 2 Sg4  (562) embryonic 1182-4H  (501) embryonic GM2  (427) embryonic Kc167  (462) embryonic S1  (336) embryonic S3  (544) leg disc CME L1  (429) wing disc CME-W2  (571) wing disc ML-DmD8  (642) wing disc ML-DmD9  (497) wing disc ML-DmD16-c3  (314) wing disc ML-DmD21  (927) wing disc ML-DmD32  (306) haltere disc ML-DmD17-c3  (366) eye-antennal disc ML-DmD11  (582) antennal disc ML-DmD20-c5  (690) mixed discs ML-DmD4-c1  (479) CNS ML-DmBG1-c1  (481) CNS ML-DmBG2-c2  (1135) tumorous blood cells mbn2  (896) ovary fGS/OSS  (401) ovary OSC  (293) ovary OSS  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (961) Schneider line 2 Sg4  (562) embryonic 1182-4H  (501) embryonic GM2  (427) embryonic Kc167  (462) embryonic S1  (336) embryonic S3  (544) leg disc CME L1  (429) wing disc CME-W2  (571) wing disc ML-DmD8  (642) wing disc ML-DmD9  (497) wing disc ML-DmD16-c3  (314) wing disc ML-DmD21  (927) wing disc ML-DmD32  (306) haltere disc ML-DmD17-c3  (366) eye-antennal disc ML-DmD11  (582) antennal disc ML-DmD20-c5  (690) mixed discs ML-DmD4-c1  (479) CNS ML-DmBG1-c1  (481) CNS ML-DmBG2-c2  (1135) tumorous blood cells mbn2  (896) ovary fGS/OSS  (401) ovary OSC  (293) ovary OSS  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    961 Schneider line 2 Sg4    562 embryonic 1182-4H    501 embryonic GM2    427 embryonic Kc167    462 embryonic S1    336 embryonic S3    544 leg disc CME L1    429 wing disc CME-W2    571 wing disc ML-DmD8    642 wing disc ML-DmD9    497 wing disc ML-DmD16-c3    314 wing disc ML-DmD21    927 wing disc ML-DmD32    306 haltere disc ML-DmD17-c3    366 eye-antennal disc ML-DmD11    582 antennal disc ML-DmD20-c5    690 mixed discs ML-DmD4-c1    479 CNS ML-DmBG1-c1    481 CNS ML-DmBG2-c2    1135 tumorous blood cells mbn2    896 ovary fGS/OSS    401 ovary OSC    293 ovary OSS    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    194 cold shock, 4-day adult    163 heat shock, 4-day adult    340 Cadmium 50 mM 6 hrs, larvae L3    485 Cadmium 50 mM 12 hrs, larvae L3    427 Cadmium 50 mM 48 hrs, 4-day adult    259 Cadmium 100 mM 48 hrs, 4-day adult    255 Copper 0.5 mM 12 hrs, larvae L3    182 Copper 15 mM 48 hrs, 4-day adult    179 Zinc 5 mM 12 hrs, larvae L3    173 Zinc 4.5 mM 48 hrs, 4-day adult    182 Ethanol 2.5% 3 hrs, larvae L3    459 Ethanol 5% 3 hrs, larvae L3    477 Ethanol 10% 3 hrs, larvae L3    396 Caffeine 1.5 mg/ml 4 hrs, larvae L3    394 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    125 Paraquat 5 mM 48 hrs, 4-day adult    353 Paraquat 10 mM 48 hrs, 4-day adult    359 Rotenone 2 μg 12 hrs, larvae L3    450 Rotenone 8 μg 12 hrs, larvae L3    460 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (194) cold shock, 4-day adult  (163) heat shock, 4-day adult  (340) Cadmium 50 mM 6 hrs, larvae L3  (485) Cadmium 50 mM 12 hrs, larvae L3  (427) Cadmium 50 mM 48 hrs, 4-day adult  (259) Cadmium 100 mM 48 hrs, 4-day adult  (255) Copper 0.5 mM 12 hrs, larvae L3  (182) Copper 15 mM 48 hrs, 4-day adult  (179) Zinc 5 mM 12 hrs, larvae L3  (173) Zinc 4.5 mM 48 hrs, 4-day adult  (182) Ethanol 2.5% 3 hrs, larvae L3  (459) Ethanol 5% 3 hrs, larvae L3  (477) Ethanol 10% 3 hrs, larvae L3  (396) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (394) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (125) Paraquat 5 mM 48 hrs, 4-day adult  (353) Paraquat 10 mM 48 hrs, 4-day adult  (359) Rotenone 2 μg 12 hrs, larvae L3  (450) Rotenone 8 μg 12 hrs, larvae L3  (460) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (194) cold shock, 4-day adult  (163) heat shock, 4-day adult  (340) Cadmium 50 mM 6 hrs, larvae L3  (485) Cadmium 50 mM 12 hrs, larvae L3  (427) Cadmium 50 mM 48 hrs, 4-day adult  (259) Cadmium 100 mM 48 hrs, 4-day adult  (255) Copper 0.5 mM 12 hrs, larvae L3  (182) Copper 15 mM 48 hrs, 4-day adult  (179) Zinc 5 mM 12 hrs, larvae L3  (173) Zinc 4.5 mM 48 hrs, 4-day adult  (182) Ethanol 2.5% 3 hrs, larvae L3  (459) Ethanol 5% 3 hrs, larvae L3  (477) Ethanol 10% 3 hrs, larvae L3  (396) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (394) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (125) Paraquat 5 mM 48 hrs, 4-day adult  (353) Paraquat 10 mM 48 hrs, 4-day adult  (359) Rotenone 2 μg 12 hrs, larvae L3  (450) Rotenone 8 μg 12 hrs, larvae L3  (460) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    194 cold shock, 4-day adult    163 heat shock, 4-day adult    340 Cadmium 50 mM 6 hrs, larvae L3    485 Cadmium 50 mM 12 hrs, larvae L3    427 Cadmium 50 mM 48 hrs, 4-day adult    259 Cadmium 100 mM 48 hrs, 4-day adult    255 Copper 0.5 mM 12 hrs, larvae L3    182 Copper 15 mM 48 hrs, 4-day adult    179 Zinc 5 mM 12 hrs, larvae L3    173 Zinc 4.5 mM 48 hrs, 4-day adult    182 Ethanol 2.5% 3 hrs, larvae L3    459 Ethanol 5% 3 hrs, larvae L3    477 Ethanol 10% 3 hrs, larvae L3    396 Caffeine 1.5 mg/ml 4 hrs, larvae L3    394 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    125 Paraquat 5 mM 48 hrs, 4-day adult    353 Paraquat 10 mM 48 hrs, 4-day adult    359 Rotenone 2 μg 12 hrs, larvae L3    450 Rotenone 8 μg 12 hrs, larvae L3    460 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    194 cold shock, 4-day adult    163 heat shock, 4-day adult    340 Cadmium 50 mM 6 hrs, larvae L3    485 Cadmium 50 mM 12 hrs, larvae L3    427 Cadmium 50 mM 48 hrs, 4-day adult    259 Cadmium 100 mM 48 hrs, 4-day adult    255 Copper 0.5 mM 12 hrs, larvae L3    182 Copper 15 mM 48 hrs, 4-day adult    179 Zinc 5 mM 12 hrs, larvae L3    173 Zinc 4.5 mM 48 hrs, 4-day adult    182 Ethanol 2.5% 3 hrs, larvae L3    459 Ethanol 5% 3 hrs, larvae L3    477 Ethanol 10% 3 hrs, larvae L3    396 Caffeine 1.5 mg/ml 4 hrs, larvae L3    394 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    125 Paraquat 5 mM 48 hrs, 4-day adult    353 Paraquat 10 mM 48 hrs, 4-day adult    359 Rotenone 2 μg 12 hrs, larvae L3    450 Rotenone 8 μg 12 hrs, larvae L3    460 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (194) cold shock, 4-day adult  (163) heat shock, 4-day adult  (340) Cadmium 50 mM 6 hrs, larvae L3  (485) Cadmium 50 mM 12 hrs, larvae L3  (427) Cadmium 50 mM 48 hrs, 4-day adult  (259) Cadmium 100 mM 48 hrs, 4-day adult  (255) Copper 0.5 mM 12 hrs, larvae L3  (182) Copper 15 mM 48 hrs, 4-day adult  (179) Zinc 5 mM 12 hrs, larvae L3  (173) Zinc 4.5 mM 48 hrs, 4-day adult  (182) Ethanol 2.5% 3 hrs, larvae L3  (459) Ethanol 5% 3 hrs, larvae L3  (477) Ethanol 10% 3 hrs, larvae L3  (396) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (394) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (125) Paraquat 5 mM 48 hrs, 4-day adult  (353) Paraquat 10 mM 48 hrs, 4-day adult  (359) Rotenone 2 μg 12 hrs, larvae L3  (450) Rotenone 8 μg 12 hrs, larvae L3  (460) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (194) cold shock, 4-day adult  (163) heat shock, 4-day adult  (340) Cadmium 50 mM 6 hrs, larvae L3  (485) Cadmium 50 mM 12 hrs, larvae L3  (427) Cadmium 50 mM 48 hrs, 4-day adult  (259) Cadmium 100 mM 48 hrs, 4-day adult  (255) Copper 0.5 mM 12 hrs, larvae L3  (182) Copper 15 mM 48 hrs, 4-day adult  (179) Zinc 5 mM 12 hrs, larvae L3  (173) Zinc 4.5 mM 48 hrs, 4-day adult  (182) Ethanol 2.5% 3 hrs, larvae L3  (459) Ethanol 5% 3 hrs, larvae L3  (477) Ethanol 10% 3 hrs, larvae L3  (396) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (394) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  125 Paraquat 5 mM 48 hrs, 4-day adult  (353) Paraquat 10 mM 48 hrs, 4-day adult  (359) Rotenone 2 μg 12 hrs, larvae L3  (450) Rotenone 8 μg 12 hrs, larvae L3  (460) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    194 cold shock, 4-day adult    163 heat shock, 4-day adult    340 Cadmium 50 mM 6 hrs, larvae L3    485 Cadmium 50 mM 12 hrs, larvae L3    427 Cadmium 50 mM 48 hrs, 4-day adult    259 Cadmium 100 mM 48 hrs, 4-day adult    255 Copper 0.5 mM 12 hrs, larvae L3    182 Copper 15 mM 48 hrs, 4-day adult    179 Zinc 5 mM 12 hrs, larvae L3    173 Zinc 4.5 mM 48 hrs, 4-day adult    182 Ethanol 2.5% 3 hrs, larvae L3    459 Ethanol 5% 3 hrs, larvae L3    477 Ethanol 10% 3 hrs, larvae L3    396 Caffeine 1.5 mg/ml 4 hrs, larvae L3    394 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    125 Paraquat 5 mM 48 hrs, 4-day adult    353 Paraquat 10 mM 48 hrs, 4-day adult    359 Rotenone 2 μg 12 hrs, larvae L3    450 Rotenone 8 μg 12 hrs, larvae L3    460 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • RH04493 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033699 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8857-RB;CG8857-RA;CG8857-RC
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal RpS11GD13530 lethal | pupal stage, with Scer\GAL4pnr-MD237 RpS11GD13530 Other Phenotypes Allele neuroanatomy defective | larval stage RpS11GD13530 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage RpS11GD13530 ganglion mother cell | larval stage RpS11GD13530
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of RpS11 Class Mutagen Stocks Known lesion RpS11NP0211 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpS11 Class Mutagen Stocks Known lesion RpS11GD13530 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13530} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}RpS11NP0211 No
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity (Akaboshi and Inoue, 1997) inferred from sequence or structural similarity with NCBI_gi:4506681 (FlyBase, 1992-)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity (Akaboshi and Inoue, 1997) inferred from sequence or structural similarity with NCBI_gi:4506681 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosolic small ribosomal subunit inferred from sequence or structural similarity (Akaboshi and Inoue, 1997) inferred from sequence or structural similarity with NCBI_gi:4506681 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
RpS11 - AR-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Arf51F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Ate1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG10175 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG1092 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG11060 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG11109 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG11188 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG11279 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG12104 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG12116 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG12301 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG12744 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG14253 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG14544 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG14556 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG14615 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15044 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15220 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15345 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15661 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15743 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG15877 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG16817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG2772 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG3061 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG31675 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG3548 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG3703 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG4951 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG5213 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG5516 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG5745 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG5886 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG6227 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG6654 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG7339 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG7829 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG8298 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG8379 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG8924 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG8965 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG9114 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CG9773 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Cchl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - ChLD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CkIIβ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Clc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - CycY anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Cyp4ad1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Cyp6a21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Dic61B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Dsp1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Fas3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Fkbp13 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Gen anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - HDAC6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Inx3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Jra anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - LBR anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Lmpt anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Lst8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Mis12 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Nep2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Obp44a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - PGRP-LE experimental knowledge based (Guruharsha et al., 2011) RpS11 - Pka-C1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - RASSF8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Rab9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Rca1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - RhoBTB anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Rpn9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Sap30 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Tip60 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Upf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Vap-33-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - Vha44 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - crn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - ct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - dlg1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - dsx-c73A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - eIF4E-4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - eya anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - gcl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - hpo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - kay anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - l(2)37Bb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - mael anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - mib1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - obst-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - p130CAS anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - pho anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - pigeon anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - spoon anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - trpml anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - vig anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RpS11 - wek anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpS11 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62099 DroID - A comprehensive database of gene and protein interactions. • FBgn0033699 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36321
Orthologs
OrthoDB Orthologs (47) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QVCZD Dipteran inclusive ortholog search EOG6S1TH9 Insect inclusive ortholog search EOG6K998G Arthropod inclusive ortholog search EOG6H9W34 Metazoa inclusive ortholog search EOG6RRKCC
Orthologs in Drosophila Species (EOG6QVCZD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpS11     Drosophila simulans   Dsim\GD15239 Y   Drosophila sechellia   Dsec\GM20375 Y   Drosophila erecta   Dere\GG22596 Y   Drosophila yakuba   Dyak\GE13464 Y   Drosophila ananassae   Dana\GF12077 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21371 Y   Drosophila persimilis   Dper\GL11264 Y   Drosophila willistoni   Dwil\GK22117 Y   Drosophila virilis   Dvir\GJ21555 Y   Drosophila mojavensis   Dmoj\GI18949 Y   Drosophila grimshawi   Dgri\GH22980 Y
Orthologs in non-Drosophila Dipterans (EOG6S1TH9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\RpS11   Anopheles gambiae Malaria mosquito  Agam\AGAP012798   Anopheles gambiae Malaria mosquito  Agam\RpS11   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006623
Orthologs in non-Dipteran Insects (EOG6K998G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RpS11   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013027   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16366   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH25306   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16365   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH26113   Atta cephalotes Leafcutter ant  Acep\ACEP20180   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22276   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21668   Linepithema humile Argentine ant  Lhum\LH18607   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11682   Solenopsis invicta Red fire ant  Sinv\SINV23381   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009948   Bombyx mori Silkmoth  Bmor\BGIBMGA013792   Pediculus humanus Human body louse  Phum\PHUM593550   Tribolium castaneum Red flour beetle  Tcas\TC009438
Orthologs in non-Insect Arthropods (EOG6H9W34)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_230714   Ixodes scapularis Deer tick  Isca\ISCW024761   Ixodes scapularis Deer tick  Isca\ISCW008334
Orthologs in non-Arthropod Metazoa (EOG6RRKCC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rps-11   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022682gn   Danio rerio Zebrafish  Drer\rps11   Danio rerio Zebrafish  Drer\si:dkey-159f12.2   Xenopus tropicalis Western clawed frog  Xtro\rps11   Gallus gallus Domestic chicken  Ggal\RPS11   Mus musculus House mouse  Mmus\Rps11   Mus musculus House mouse  Mmus\Gm9808   Rattus norvegicus Norway rat  Rnor\RGD1563352   Rattus norvegicus Norway rat  Rnor\RGD1565560   Rattus norvegicus Norway rat  Rnor\Rps11   Homo sapiens Human  Hsap\RPS11
Human Orthologs (1)
Gene OMIM HGNC Hsap\RPS11
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15239 Drosophila sechellia Dsec\GM20375 Drosophila erecta Dere\GG22596 Drosophila yakuba Dyak\GE13464 Drosophila ananassae Dana\GF12077 Drosophila pseudoobscura pseudoobscura Dpse\GA21371 Drosophila persimilis Dper\GL11264 Drosophila willistoni Dwil\GK22117 Drosophila virilis Dvir\GJ21555 Drosophila mojavensis Dmoj\GI18949 Drosophila grimshawi Dgri\GH22980
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Kyoto	103557 y* w*; P{GawB}RpS11NP0211 / CyO, P{UAS-lacZ.UW14}UW14
VDRC	v23475 w1118; P{GD13530}v23475 v23477 w1118; P{GD13530}v23477/TM3
Genomic Clones ( 1 )
	BACR37I09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 453 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE28480 RH03287
Other clones	RH04493 yak-ad_CG8857 yak-em_CG8857
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH10440 GH10776 GH10838 GH11078 GH11825 GH14292 GH15994 GH17883 GH18683 GH19588 GH20014 GH20082 GH20216 GH22365 GH22785 GH23192 GH23585 GH25078 GH25130 GH25745 GH28683 GM05789 GM10863 GM13411 GM14690 GM15720 GM18284 GM18694 GM21330 GM23129 GM24731 GM26005 GM29367 GM29758 GM30179 GM30357 LD09749 LD16769 LD21716 LD27663 LD35543 LD47695 LD48004 LP03925 LP05078 LP05173 LP06943 LP08258 LP14413 LP15150 LP16119 LP19804 LP20308 RE05106 RE07329 RE10750 RE11494 RE12340 RE14348 RE19468 RE21228 RE21821 RE26460 RE28248 RE28624 RE29462 RE32883 RE35573 RE35896 RE38624 RE41722 RE47411 RE48717 RE49458 RE50617 RE51358 RE51868 RE53494 RE54133 RE55783 RE57378 RE57733 RE65013 RE69742 RE70027 RE72068 RH04380 RH05454 RH08833 RH11604 RH12275 RH15413 RH18451 RH21469 RH22281 RH30648 RH31339 RH39136 RH44291 RH47793 RH49605 RH50684 RH51124 RH51318 RH51980 RH54284 RH56669 RH57930 RH62523 RH63065 RH66593 RH68636 RH74590 SD02420 SD03656 SD05562 SD11032 SD11442 SD11451 SD11877 SD12196 SD12954 SD14338 SD14442 SD15431 SD15768 SD16057 SD16616 SD17063 SD17553 SD17659 SD17677 SD17678 SD19219 SD19910 SD19917 SD20289 SD21495 SD22302 SD23183 SD23222 SD23285 SD23355 SD24340 SD24635 SD27280 SD27442
Other clones	8760 11222 12404 12613 42493 56495 60787 61602 100782 144724 165809 191232 473642 522706 522834 523969 524756 525461 527096 556898 557946 561903 562083 568856 569692 AA433211 AT30351 CK01.2C.F12 Dmel_dig_000336_0661_3644 Dmel_dig_000397_0694_0383 Dmel_dig_000405_0714_0307 Dmel_dig_001503_0676_3644 Dmel_dig_001630_0583_2424 Dmel_dig_002037_0692_1578 Dmel_dig_002268_0696_2507 Dmel_dig_002604_0678_2255 Dmel_dig_003194_0663_0442 Dmel_dig_003204_0656_0571 Dmel_dig_003611_0671_0395 Dmel_dig_003806_0708_2315 Dmel_dig_004124_0656_0881 Dmel_dig_004574_0688_2386 Dmel_dig_004819_0592_1999 Dmel_dig_004986_0671_3392 Dmel_dig_005165_0614_0413 Dmel_dig_005461_0707_1433 Dmel_dig_005704_0608_2224 Dmel_dig_005971_0619_0354 Dmel_dig_006034_0688_1879 Dmel_dig_006250_0710_1120 Dmel_dig_006257_0635_1269 Dmel_dig_007121_0638_1855 Dmel_dig_007750_0656_2576 Dmel_dig_008131_0707_1139 Dmel_dig_008856_0625_1175 Dmel_dig_009255_0686_0787 Dmel_dig_009832_0639_2710 Dmel_dig_010845_0595_3319 Dmel_dig_012070_0696_2439 Dmel_dig_012128_0596_2826 Dmel_dig_012368_0663_1339 Dmel_dig_013260_0670_3419 Dmel_dig_013860_0628_2892 Dmel_dig_014035_0683_3494 Dmel_dig_014543_0586_2110 Dmel_dig_014605_0667_2186 Dmel_dig_015211_0683_1789 Dmel_dig_015340_0605_2764 Dmel_dig_016577_0658_1938 Dmel_dig_016590_0587_1225 Dmel_dig_016945_0710_1926 Dmel_dig_017065_0600_1263 Dmel_dig_017295_0595_2607 Dmel_dig_018190_0582_3035 Dmel_dig_018265_0649_3058 Dmel_dig_018388_0591_2037 Dmel_dig_019779_0672_1054 Dmel_dig_020084_0700_3258 Dmel_dig_021251_0585_3159 Dmel_neb_003793_0679_3632 Dmel_neb_006221_0828_1301 Dmel_neb_009291_0367_3531 Dmel_neb_010722_0081_2283 Dmel_neb_011061_0092_0464 Dmel_neb_011090_0699_0460 Dmel_neb_011136_0599_0464 Dmel_neb_011478_0088_1438 Dmel_neb_012887_0578_3144 Dmel_neb_013288_0327_2946 Dmel_neb_013360_0940_2802 Dmel_neb_013381_0336_0830 Dmel_neb_013762_0123_2163 Dmel_neb_014471_0886_2247 Dmel_neb_014650_0924_1657 Dmel_neb_014716_0849_0761 Dmel_neb_014767_0627_2420 Dmel_neb_014919_0443_3101 Dmel_neb_015217_0207_0628 Dmel_neb_015226_0440_2224 Dmel_neb_015381_0652_2561 Dmel_neb_015413_0117_1705 Dmel_neb_015431_0838_2513 Dmel_neb_015601_0607_3429 Dmel_neb_015618_0617_0779 Dmel_neb_015749_0347_1818 Dmel_neb_016005_0906_0793 EC05996 EC13339 EC13603 EC14466 EC14761 EC14829 EC14839 EC14922 EC22038 EC22110 EC22243 EC24296 EC25329 EC25506 EC28487 EC30227 EC30505 EC33490 EC34338 EC34527 EC37729 EC39780 EC40066 EC40271 EC40580 EC052777 EK007242 EK065814 EK111349 EK114013 EK145503 EK157210 EK169126 EK174561 EK184954 EK185627 EK213405 EK223340 EK251914 EK270256 EK293837 EN00424 EN02106 EN02615 EN02864 EN04528 EN05706 EN05850 EN06545 EN07250 EN11640 EN11902 EN12712 EN13340 EN13658 EN14049 ESG0110c.E21.1_C02 ESG0114b.B21_C09 ESG0116b.B21_G09 ESG0117b.B21_B01 ESG0119b.B21_C04 FGC001B11 FGC003B08 FGC018D06 FGC018F12 FGC021A06 FGC021B09 FGC023E03 FGC023G08 FGC023H03 FGC025A01 FGH001F10 FGH109D09 FGH111E04 FGH111E08 FGH115F12 FGH117H09 FGH124D08 FGH125C02 FGH127E05 FGM002H10 FGM104A11 FGM104H02 FGM209B05 FGM211D08 FGM214C04 FGM214F03 FGM215B06 FGM227B10 FGM228B09 FGM231A04 FGM235B12 FGM304H10 FGM307E07 FGM307G09 FGM311D05 FGM319G03 FGM325A12 FGM325H10 FGX001F08 GH10738 GM02965 GM04995 GM06068 GM06763 GM09971 GM10426 GM14554 GM15256 GM17111 GM18080 GM21711 GM23616 GM26394 GM27183 GM27760 GM28221 GM30474 GM32235 IP04747 IP08838 IP11729 LD07921 LD21740 LD29035 LP22945 RE02423 RE02491 RE07843 RE08924 RE09818 RE10088 RE26239 RE38310 RE39613 RE41676 RE42457 RE44708 RH05513 RH06767 RH07754 RH07765 RH08821 RH18489 RH20232 RH20292 RH20437 RH20753 RH20852 RH20885 RH30417 RH63169 RH69211 RH71711 RP004097751 RP004104654 RP004138531 RP004170613 RP004176151 RP004220821 RP004252092 RP004265175 RP004369507 RP004389539 RP004394853 RP004410670 RP004421111 RP004438014 RP004470128 RP004478081 RP004479783 RP004480002 RP004517614 RP004535050 SD12619 SD13837 SD14832 SD17350 SD18040 SD18213 SD21282 SD22141 SD22794 SD23075 SD24232 SD24439 SD24794 SD25177 SD25365 SD26892 SD27247 SD27766 SD27829 UUGC0598 UUGC0964
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033699 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36321
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG8857 anon-EST:fe1D2 (Bayraktaroglu, 2000.11.2) Source for merge of: RpS11 anon-MMS23 (FlyBase, 1996-)
Additional comments
Other Comments
	Haploinsufficient locus. (Cook et al., 2012) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Minute gene. (Marygold et al., 2007) Molecularly-defined mutations in RpS11 result in Minute phenotypes. (Marygold et al., 2007) RpS11 lies in a gap in deletion coverage. (Marygold et al., 2007) Transcript induced by MMS treatment of S1CII cells. (Akaboshi and Inoue, 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165868 NM_165869 RefSeq (Proteins) • NP_725114 NP_725115 DDBJ / EMBL / GenBank • AA433211 AAM71028 AAM71029 Entrez Gene - A searchable database of RefSeq genes. • 36321 UniProtKB/Swiss-Prot • Q0E9B6 UniProtKB/TrEMBL • A1Z8U9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S17 (IPR000266) Nucleic acid-binding, OB-fold (IPR012340) Ribosomal protein S17, conserved site (IPR019979) Ribosomal protein S17, archaeal (IPR019978) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH04493
Linkouts
	BioGRID - A database of protein and genetic interactions • 62099 DroID - A comprehensive database of gene and protein interactions. • FBgn0033699 DRSC - Results from RNAi screens. • FBgn0033699 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033699 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8857-RB;CG8857-RA;CG8857-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033699 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36321 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36321 modMine - Data generated by the modENCODE project. • FBgn0033699
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	anon-EST:fe1D2   anon-MMS23   CG8857 (Ceriani et al., 2002, Huang et al., 2005, Wang et al., 2004, Goshima et al., 2007, Herranz et al., 2012, Marygold et al., 2007, Saulière et al., 2010, Cammarato et al., 2011) clone 23 (Akaboshi and Inoue, 1997) M(2)48E (Marygold et al., 2007) RpS11 (Fischer et al., 2012, Goshima et al., 2007, Marygold et al., 2007, Abruzzi et al., 2011, Cook et al., 2012, Lindquist et al., 2011) RPS11 (Coléno-Costes et al., 2012) S11 (Brogna et al., 2002, Carpenter et al., 2009) unnamed (Schmid and Tautz, 1997)
Name Synonym	anon-fast-evolving-1D2   Ribosomal protein S11 (Ashburner and Marygold, 2004.7.2, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0025258 FBgn0025784
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 15 ) Supplementary material  ( 8 ) Review  ( 1 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 3 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 7 )
	Coléno-Costes et al., 2012, PLoS Genet. 8(10): e1003006 New partners in regulation of gene expression: the enhancer of trithorax and polycomb corto interacts with methylated ribosomal protein l12 via its chromodomain. [FBrf0219702] Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Fischer et al., 2012, Proc. Biol. Sci. 279(1738): 2636--2644 Conserved properties of Drosophila and human spermatozoal mRNA repertoires. [FBrf0218415] Herranz et al., 2012, BMC Genomics 13: 52 Microgravity simulation by diamagnetic levitation: effects of a strong gradient magnetic field on the transcriptional profile of Drosophila melanogaster. [FBrf0217750] Abruzzi et al., 2011, Genes Dev. 25(22): 2374--2386 Drosophila CLOCK target gene characterization: implications for circadian tissue-specific gene expression. [FBrf0216798] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Lindquist et al., 2011, Genome Res. 21(3): 433--446 Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. [FBrf0213199] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...