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Gene Dmel\CG8818

General Information
Symbol	Dmel\CG8818	Species	D. melanogaster
Name		Annotation symbol	CG8818
Feature type	protein_coding_gene	FlyBase ID	FBgn0033751
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	49A10-49A10	Sequence location	2R:8,404,760..8,406,423 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8818 (FBgn0033751). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transferase activity, transferring phosphorus-containing groups. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631766_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8818. Gene sequence location is 2R:8404760..8406423.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN30426 HFA07275
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 49A10-49A10   Limits computationally determined from genome sequence between P{lacW}fdlk17040 and P{EP}CG8569EP1182
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8818 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8818-RA FBtr0087941  NM_136950   1550   429
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8818-PA   FBpp0087052   48.6   429   8.53     NP_610794   AAF58495
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (IPR009076)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141790   AA141943   AA141957   AA141968   AA696696   AA804096   AE013599 AAF58495   AI063792   AI063895   AI134159   AI293197   AI388984   AW940153   AY060613 AAL28161   BF493228   BF504122   BF506218   BF506685   BF506702   BG640327   BG640380   BG641129   BI232147   BI482020   BI565497   BI569750   BI570516   BI572507   BI587192   BI589997   BI590327   BI609405   BI618669   BI619816   BI619888   BI628855   BI638912   BP554001   BP559701   CO297613   CO300875   CO306691   EC087797   EC088747   EC226089   EC234136   EC245848   EC264037   EL876368   EV593991   FD585487   FD585723   FD585761   FD586253   FD586881   FD587485   GH738933   GH739753   GH740022   GH743397   GH745000   GH745638   GH766124   GH766129   GH769470   GH769850   GH779287
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7K2X0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033751    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033751 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033751 expression level Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3405) embryo 02-04hr  (2595) embryo 04-06hr  (6112) embryo 06-08hr  (6424) embryo 08-10hr  (6191) embryo 10-12hr  (7056) embryo 12-14hr  (4135) embryo 14-16hr  (4299) embryo 16-18hr  (3477) embryo 18-20hr  (3598) embryo 20-22hr  (2787) embryo 22-24hr  (3068) larva L1  (3453) larva L2  (3291) larva L3 12hr old  (2855) larva L3 puffstage 1-2  (2717) larva L3 puffstage 3-6  (3026) larva L3 puffstage 7-9  (3211) white prepupae new  (2777) white prepupae 12hr  (3428) white prepupae 24hr  (4242) pupae 2d postWPP  (3938) pupae 3d postWPP  (3479) pupae 4d postWPP  (3221) adult male 01day  (4918) adult male 05day  (6253) adult male 30day  (5463) adult female 01day  (3766) adult female 05day  (3067) adult female 30day  (3317) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3405) embryo 02-04hr  (2595) embryo 04-06hr  (6112) embryo 06-08hr  (6424) embryo 08-10hr  (6191) embryo 10-12hr  (7056) embryo 12-14hr  (4135) embryo 14-16hr  (4299) embryo 16-18hr  (3477) embryo 18-20hr  (3598) embryo 20-22hr  (2787) embryo 22-24hr  (3068) larva L1  (3453) larva L2  (3291) larva L3 12hr old  (2855) larva L3 puffstage 1-2  (2717) larva L3 puffstage 3-6  (3026) larva L3 puffstage 7-9  (3211) white prepupae new  (2777) white prepupae 12hr  (3428) white prepupae 24hr  (4242) pupae 2d postWPP  (3938) pupae 3d postWPP  (3479) pupae 4d postWPP  (3221) adult male 01day  (4918) adult male 05day  (6253) adult male 30day  (5463) adult female 01day  (3766) adult female 05day  (3067) adult female 30day  (3317) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033751 expression level Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3405) embryo 02-04hr  (2595) embryo 04-06hr  (6112) embryo 06-08hr  (6424) embryo 08-10hr  (6191) embryo 10-12hr  (7056) embryo 12-14hr  (4135) embryo 14-16hr  (4299) embryo 16-18hr  (3477) embryo 18-20hr  (3598) embryo 20-22hr  (2787) embryo 22-24hr  (3068) larva L1  (3453) larva L2  (3291) larva L3 12hr old  (2855) larva L3 puffstage 1-2  (2717) larva L3 puffstage 3-6  (3026) larva L3 puffstage 7-9  (3211) white prepupae new  (2777) white prepupae 12hr  (3428) white prepupae 24hr  (4242) pupae 2d postWPP  (3938) pupae 3d postWPP  (3479) pupae 4d postWPP  (3221) adult male 01day  (4918) adult male 05day  (6253) adult male 30day  (5463) adult female 01day  (3766) adult female 05day  (3067) adult female 30day  (3317) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3405) embryo 02-04hr  (2595) embryo 04-06hr  (6112) embryo 06-08hr  (6424) embryo 08-10hr  (6191) embryo 10-12hr  (7056) embryo 12-14hr  (4135) embryo 14-16hr  (4299) embryo 16-18hr  (3477) embryo 18-20hr  (3598) embryo 20-22hr  (2787) embryo 22-24hr  (3068) larva L1  (3453) larva L2  (3291) larva L3 12hr old  (2855) larva L3 puffstage 1-2  (2717) larva L3 puffstage 3-6  (3026) larva L3 puffstage 7-9  (3211) white prepupae new  (2777) white prepupae 12hr  (3428) white prepupae 24hr  (4242) pupae 2d postWPP  (3938) pupae 3d postWPP  (3479) pupae 4d postWPP  (3221) adult male 01day  (4918) adult male 05day  (6253) adult male 30day  (5463) adult female 01day  (3766) adult female 05day  (3067) adult female 30day  (3317) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3405 embryo 02-04hr    2595 embryo 04-06hr    6112 embryo 06-08hr    6424 embryo 08-10hr    6191 embryo 10-12hr    7056 embryo 12-14hr    4135 embryo 14-16hr    4299 embryo 16-18hr    3477 embryo 18-20hr    3598 embryo 20-22hr    2787 embryo 22-24hr    3068 larva L1    3453 larva L2    3291 larva L3 12hr old    2855 larva L3 puffstage 1-2    2717 larva L3 puffstage 3-6    3026 larva L3 puffstage 7-9    3211 white prepupae new    2777 white prepupae 12hr    3428 white prepupae 24hr    4242 pupae 2d postWPP    3938 pupae 3d postWPP    3479 pupae 4d postWPP    3221 adult male 01day    4918 adult male 05day    6253 adult male 30day    5463 adult female 01day    3766 adult female 05day    3067 adult female 30day    3317 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033751    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033751 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult thoracico-abdominal ganglion, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033751 expression level Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion  524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland  (598.8) Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033751 expression level Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion  524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland  598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    336.75 Larval Midgut    235.1 Larval Hindgut    295.4 Larval Malpighian Tubules    180 Larval Fat Body    126.6 Larval Salivary Gland    360.5 Larval Trachea    378.525 Larval Carcass    307.875 Adult Head    241.9 Adult Eye    256.125 Adult Brain    496.2 Adult Thoracic-Abdominal Ganglion    524.2 Adult Crop    302.6 Adult Midgut    207.5 Adult Hindgut    388.4 Adult Malpighian Tubules    320.2 Adult Fat Body    126.9 Adult Salivary Gland    428.1 Adult Heart    292.85 Adult VirginFemale Spermatheca    228.6 Adult InseminatedFemale Spermatheca    200.2 Adult Ovary    146.1 Adult Testis    200.7 Adult Male Accessory Gland    598.8 Adult Carcass    347.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    241.9   NA  Eye    256.125   NA  Brain    496.2   336.75  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    524.2   NA  Crop    302.6   235.1  Midgut    207.5   295.4  Hindgut    388.4   180  Malpighian Tubules    320.2   126.6  Fat Body    126.9   360.5  Salivary Gland    428.1   NA  Heart    292.85   378.525  Trachea    NA   NA  VirginFemale Spermatheca    228.6   NA  InseminatedFemale Spermatheca    200.2   NA  Ovary    146.1   NA  Testis    200.7   NA  Male Accessory Gland    598.8   307.875  Carcass    347.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_31
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033751 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8818-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8818 Stages(s) 1-3 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8818GD14037 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG8818 Class Mutagen Stocks Known lesion CG8818SH1564 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8818 Class Mutagen Stocks Known lesion CG8818GD14037 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14037} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}CG8818SH1564 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
transferase activity, transferring phosphorus-containing groups inferred from electronic annotation with InterPro:IPR009076 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8818 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0033751
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12446 Dere\GG22572 Dgri\GH20568 Dmoj\GI19762 Dper\GL10212 Dpse\GA21344 Dsec\GM20353 Dsim\GD25832 Dvir\GJ18206 Dwil\GK19480 Dyak\GE13441
Curated drosophilid orthologs	Dpse\GA21344
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP005198-PA Anopheles gambiae (mosquito) CPIJ006565 Culex pipens (mosquito) XP_975595.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231115 FBgn0221478 FBgn0205371 FBgn0197112 FBgn0175236 FBgn0081332 FBgn0147822 FBgn0142499 FBgn0128031 FBgn0114743 FBgn0089483 CPIJ006565 ACYPI001136 AGAP005198 AAEL014641 GLEAN_08796
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v28957 w1118; P{GD14037}v28957/CyO
Genomic Clones ( 1 )
	BACR24H09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 63 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH04007
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01542 AT05420 AT08638 AT09235 AT09256 GH03772 GH11536 GH16317 GH20051 GM08177 GM12823 RE28165 RE64660 RH01891 RH02861 RH03537 RH03932 RH08042 RH14180 RH27685 RH49549 RH50934 RH51021 RH57615 RH63277 SD11317 SD11381 SD12383 SD21316
Other clones	46877 54502 103172 122068 144722 533479 CK00044 CK00064 CK02474 Dmel_neb_005153_0633_0903 EK170204 EK179560 EK251915 FGM227D12 FGM322D07 IP06301 RM04257 RM04457 RM04657 RM04757 RM04857 RM04957 RP001002342 RP001005659 RP001015756 RP001020976 RP001021337 RP001021906 RP001025884 RP001034239 RP001043511 RP001046703 RP001053677
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033751 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36375
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136950 RefSeq (Proteins) • NP_610794 DDBJ / EMBL / GenBank • AAF58495 AAL28161 AI063895 AW940153 AY060613 Entrez Gene - A searchable database of RefSeq genes. • 36375 UniProtKB/TrEMBL • Q7K2X0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (IPR009076)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0033751 DRSC - Results from RNAi screens. • FBgn0033751 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033751 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8818-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033751 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36375 InParanoid A subset of ortholog calls from InParanoid. • AGAP005198-PA Anopheles gambiae (mosquito) CPIJ006565 Culex pipens (mosquito) XP_975595.1 Tribolium castaneum (red flour beetle) modMine - Data generated by the modENCODE project. • FBgn0033751 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231115 FBgn0221478 FBgn0205371 FBgn0197112 FBgn0175236 FBgn0081332 FBgn0147822 FBgn0142499 FBgn0128031 FBgn0114743 FBgn0089483 CPIJ006565 ACYPI001136 AGAP005198 AAEL014641 GLEAN_08796
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8818 (Wasbrough et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 9 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Wasbrough et al., 2010, J. Proteomics 73(11): Supplemental Table 1. Mass spectrometry data. [FBrf0213252] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]