Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Component of the NTC(Nineteen)/Prp19 complex composed of at least fand, Prp19,CG9667/ISY1 and Cdc5/CDC5L. Within the complex, interacts with Prp19 and ISY1/CG9667.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fand using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\fand in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: fand CG6197
The 'faint sausage (fas)' phenotype, previously associated the immunoglobulin domain protein CG17716 (Lekven et al, 1998; FBrf0103312), is now shown to be caused by mutations in CG6197, also known as 'fand' (Guilgur et al, 2014; FBrf0224810).
FlyBase curator comment: Based on their findings, Sauerwald et al, 2017 (FBrf0234822) refer to the CG6197/fand gene as 'fas'. However, given the history, it would likely be confusing to effectively transfer the 'fas/faint sausage' nomenclature from the CG17716 gene to the fand/CG6197 gene in FlyBase. Thus, FlyBase has: (i) retained 'fand/fandango' as the FlyBase symbol/name of CG6197 (based on FBrf0224810), but added 'fas/faint sausage' as synonyms (based on FBrf0234822); and (ii) reverted the current 'fas/faint sausage' gene to just have 'CG17716' as its FlyBase symbol (at least until it is given a more appropriate symbol/name), while retaining 'fas/faint sausage' as synonyms.
Splicing of early zygotic, but not maternally encoded pre-mRNAs is affected in mutant embryos.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
The gene is named "fandango", after the Iberian folk dance, based on the phenotype of mutant embryos.