dArc1
Please see the GBrowse view of Dmel\Arc1 or the JBrowse view of Dmel\Arc1 for information on other features
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Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Homooligomer; homooligomerizes into virion-like capsids.
The protein is evolutionarily related to retrotransposon Gag proteins (PubMed:29328915, PubMed:29328916). It contains structural elements found within viral Gag polyproteins originated from the Ty3/gypsy retrotransposon family and retains the ability to form virion-like capsid structures that can mediate mRNA transfer between cells (PubMed:29328915, PubMed:29328916). Tetrapod and fly Arc protein-coding genes originated independently from distinct lineages of Ty3/gypsy retrotransposons (PubMed:29328916).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Arc1 using the Feature Mapper tool.
Arc1 is expressed in a number of large neurons that innervate the larval ring gland. It is expressed in all dilp+ median cells and in several other pars neurosecretory cells.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Arc1 in GBrowse 22-70
2-70
2-75.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: Arc1 CG12505
Source for merge of: CG12505 anon-WO0153538.31 anon-WO0153538.40 anon-WO0153538.41 anon-WO0153538.43 anon-WO0153538.45
Source for merge of CG12505 anon-WO0153538.31 anon-WO0153538.40 anon-WO0153538.41 anon-WO0153538.43 anon-WO0153538.45 was sequence comparison ( date:051113 ).
Arc1 mutants are starvation-resistant, exhibiting an increased time of survival in the absence of food.
