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Gene Dmel\CG12863

General Information
Symbol	Dmel\CG12863	Species	D. melanogaster
Name		Annotation symbol	CG12863
Feature type	protein_coding_gene	FlyBase ID	FBgn0033948
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	51B6-51B6	Sequence location	2R:10,507,303..10,508,820 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12863 (FBgn0033948). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA methylase, N-6 adenine-specific, eukaryotic; Zinc finger, CCHC retroviral-type; Zinc finger, CCHC-type; Zinc finger, CTCHY-type; Zinc finger, DHHC-type, palmitoyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult female reproductive system, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1635428_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG12863. Gene sequence location is 2R:10507303..10508820.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA06203 BKN20547
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 51B6-51B6   Limits computationally determined from genome sequence between P{lacW}ttvk03617&P{EP}ttvEP765 and P{lacW}Rpn6k00103
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12863 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	<new comment>CG12863 structure from gene prediction. Final exon enlarged to include region of BLASTX homology. DGC clone RE24565 appears problematic: unspliced intron
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12863-RA FBtr0087500  NM_137129   1412   437
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12863-PA   FBpp0086629   51.1   437   8.24     NP_610973   AAF58228
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, DHHC-type, palmitoyltransferase (IPR001594) Zinc finger, CCHC-type (IPR001878) Zinc finger, CTCHY-type (IPR017921) DNA methylase, N-6 adenine-specific, eukaryotic (IPR019369) Zinc finger, CCHC retroviral-type (IPR013084)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF58228   AY071205 AAL48827   BI227498   BT120242   EC076466   GH739439   GH741790   GH741900   GH741949   GH742206   GH745696   GH745896   GH747316   GH763217
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SZ05 A1Z9S8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0033948    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0033948 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0033948 expression level Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (983) embryo 02-04hr  (775) embryo 04-06hr  (784) embryo 06-08hr  (619) embryo 08-10hr  (676) embryo 10-12hr  (542) embryo 12-14hr  (475) embryo 14-16hr  (228) embryo 16-18hr  (181) embryo 18-20hr  (125) embryo 20-22hr  (157) embryo 22-24hr  (191) larva L1  (289) larva L2  (203) larva L3 12hr old  (151) larva L3 puffstage 1-2  (270) larva L3 puffstage 3-6  (354) larva L3 puffstage 7-9  (484) white prepupae new  (352) white prepupae 12hr  (493) white prepupae 24hr  (492) pupae 2d postWPP  (332) pupae 3d postWPP  (199) pupae 4d postWPP  (154) adult male 01day  (214) adult male 05day  (213) adult male 30day  (174) adult female 01day  (535) adult female 05day  (913) adult female 30day  (988) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0033948 expression level Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (983) embryo 02-04hr  (775) embryo 04-06hr  (784) embryo 06-08hr  (619) embryo 08-10hr  (676) embryo 10-12hr  (542) embryo 12-14hr  (475) embryo 14-16hr  (228) embryo 16-18hr  (181) embryo 18-20hr  125 embryo 20-22hr  (157) embryo 22-24hr  (191) larva L1  (289) larva L2  (203) larva L3 12hr old  (151) larva L3 puffstage 1-2  (270) larva L3 puffstage 3-6  (354) larva L3 puffstage 7-9  (484) white prepupae new  (352) white prepupae 12hr  (493) white prepupae 24hr  (492) pupae 2d postWPP  (332) pupae 3d postWPP  (199) pupae 4d postWPP  (154) adult male 01day  (214) adult male 05day  (213) adult male 30day  (174) adult female 01day  (535) adult female 05day  (913) adult female 30day  (988) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    983 embryo 02-04hr    775 embryo 04-06hr    784 embryo 06-08hr    619 embryo 08-10hr    676 embryo 10-12hr    542 embryo 12-14hr    475 embryo 14-16hr    228 embryo 16-18hr    181 embryo 18-20hr    125 embryo 20-22hr    157 embryo 22-24hr    191 larva L1    289 larva L2    203 larva L3 12hr old    151 larva L3 puffstage 1-2    270 larva L3 puffstage 3-6    354 larva L3 puffstage 7-9    484 white prepupae new    352 white prepupae 12hr    493 white prepupae 24hr    492 pupae 2d postWPP    332 pupae 3d postWPP    199 pupae 4d postWPP    154 adult male 01day    214 adult male 05day    213 adult male 30day    174 adult female 01day    535 adult female 05day    913 adult female 30day    988 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0033948    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0033948 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult female reproductive system, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0033948 expression level Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0033948 expression level Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    116.95 Larval Midgut no informative data Larval Hindgut    65.6 Larval Malpighian Tubules    79.7 Larval Fat Body    88.9 Larval Salivary Gland    90.1 Larval Trachea    115.6 Larval Carcass    53.1 Adult Head    49.6 Adult Eye    59.45 Adult Brain    55 Adult Thoracic-Abdominal Ganglion    56.2 Adult Crop    73.8 Adult Midgut    52.8 Adult Hindgut    49.5 Adult Malpighian Tubules    91.6 Adult Fat Body    75.2 Adult Salivary Gland    94.8 Adult Heart    68.9 Adult VirginFemale Spermatheca    95.8 Adult InseminatedFemale Spermatheca    115 Adult Ovary    204.1 Adult Testis    41.1 Adult Male Accessory Gland    124.6 Adult Carcass    54.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    49.6   NA  Eye    59.45   NA  Brain    55   116.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    56.2   NA  Crop    73.8   no informative data  Midgut    52.8   65.6  Hindgut    49.5   79.7  Malpighian Tubules    91.6   88.9  Fat Body    75.2   90.1  Salivary Gland    94.8   NA  Heart    68.9   115.6  Trachea    NA   NA  VirginFemale Spermatheca    95.8   NA  InseminatedFemale Spermatheca    115   NA  Ovary    204.1   NA  Testis    41.1   NA  Male Accessory Gland    124.6   53.1  Carcass    54.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_06
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033948 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12863-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG12863 Class Mutagen Stocks Known lesion CG12863G18229 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12863 Class Mutagen Stocks Known lesion CG12863KK100451 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG12863GD12655 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6284 (Ryder, 2004.4.26) Df(2R)Exel7133 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12655} NA P{KK100451} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG12863G18229 NA P{EPgy2}Uhg5EY04055 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR013084 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR001594, InterPro:IPR001878, InterPro:IPR013084 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12863 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62369 DroID - A comprehensive database of gene and protein interactions. • FBgn0033948 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36623
Orthologs
Genome-wide drosophilid orthologs	Dmoj\GI18794 Dwil\GK19525
Curated drosophilid orthologs	Dpse\GA11865
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004422-PA Aedes aegypti (mosquito) XP_001949879.1 Acyrthosiphon pisum (pea aphid) XP_001893611.1 Brugia malayi (roundworm nematode) BGIBMGA009901-PA Bombyx mori (silk worm) ENSBTAP00000009526 Bos taurus (bovine) CN25303 Caenorhabditis brenneri (small nematode) CBP14485 Caenorhabditis briggsae (nematode) CE17756 Caenorhabditis elegans (worm) ENSCAFP00000024205 Canis familiaris (dog) ENSCINP00000013585 Ciona intestinalis (sea squirt) JA11320 Caenorhabditis japonica (nematode) CPIJ013353 Culex pipens (mosquito) ENSCPOP00000010319 Cavia porcellus (guinea pig) RP09419 Caenorhabditis remanei (nematode) ENSCSAVP00000012636 Ciona savignyi (sedentary tunicate) 185876 Capitella spl (polychaete worm) 43964 Daphnia pulex (daphnia) ENSDARP00000022770 Danio rerio (zebra fish) ENSECAP00000005399 Equus caballus (horse) ENSGACP00000001255 Gymnopilus aculeatus (mushroom) ENSGALP00000023186 Gallus gallus (chicken) 185018 Hypsipyla robusta (cedar shoot borer) ENSP00000303468 Homo sapiens (human) ISCW000961-PA Ixodes scapularis (deer tick) ENSMODP00000000466 Monodelphis domestica (gray opossum) ENSMMUP00000020208 Macaca mulatta (rhesus monkey) ENSMUSP00000031077 Mus musculus (house mouse) XP_001606538.1 Nasonia vitripennis (wasp) ENSOANP00000010675 Ornithorynchus anatinus (platypus) ENSORLP00000024779 Oryzias latipes (japanese killifish) PHUM001810-PA Pediculus humanus (human body louse) PP26233 Pristionchus pacificus (nematode) ENSPPYP00000016365 Pongo pygmaeus (orangutan) ENSPTRP00000027482 Pan troglodytes (chimpanzee) ENSRNOP00000051233 Rattus norvegicus (norway rat) XP_001178580.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001194790.1 Strongylocentrotus purpuratus (purple sea urchin) 28284 Trichoplax adhaerens (metazoa) XP_970334.2 Tribolium castaneum (red flour beetle) ENSTNIP00000009072 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000025275 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000002081 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11520 LH18262 ISCW000961 FBgn0221523 JGI_V11_43964 FBgn0141533 CPIJ013353 BGIBMGA009901 ACYPI008533 GB17573 AAEL004422 PB25370 PHUM439080 GLEAN_05649
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	27440 y1 w*; P{EP}CG12863G18229
VDRC	v107989 P{KK100451}VIE-260B
Genomic Clones ( 2 )
	BACR07P02 BACR27M04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 12 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE24565
Other clones	MIP16609
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	104898 RP001008765 RP001024775 RP001029614 RP001033263 RP001035388 RP001042553 RP001048245 RP001050591 RP001053425
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033948 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36623
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137129 RefSeq (Proteins) • NP_610973 DDBJ / EMBL / GenBank • AAF58228 AAL48827 AY071205 BI227498 Entrez Gene - A searchable database of RefSeq genes. • 36623 UniProtKB/TrEMBL • A1Z9S8 Q8SZ05
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, DHHC-type, palmitoyltransferase (IPR001594) Zinc finger, CCHC-type (IPR001878) Zinc finger, CTCHY-type (IPR017921) DNA methylase, N-6 adenine-specific, eukaryotic (IPR019369) Zinc finger, CCHC retroviral-type (IPR013084)
Linkouts
	BioGRID - A database of protein and genetic interactions • 62369 DroID - A comprehensive database of gene and protein interactions. • FBgn0033948 DRSC - Results from RNAi screens. • FBgn0033948 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033948 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12863-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033948 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36623 InParanoid A subset of ortholog calls from InParanoid. • AAEL004422-PA Aedes aegypti (mosquito) XP_001949879.1 Acyrthosiphon pisum (pea aphid) XP_001893611.1 Brugia malayi (roundworm nematode) BGIBMGA009901-PA Bombyx mori (silk worm) ENSBTAP00000009526 Bos taurus (bovine) CN25303 Caenorhabditis brenneri (small nematode) CBP14485 Caenorhabditis briggsae (nematode) CE17756 Caenorhabditis elegans (worm) ENSCAFP00000024205 Canis familiaris (dog) ENSCINP00000013585 Ciona intestinalis (sea squirt) JA11320 Caenorhabditis japonica (nematode) CPIJ013353 Culex pipens (mosquito) ENSCPOP00000010319 Cavia porcellus (guinea pig) RP09419 Caenorhabditis remanei (nematode) ENSCSAVP00000012636 Ciona savignyi (sedentary tunicate) 185876 Capitella spl (polychaete worm) 43964 Daphnia pulex (daphnia) ENSDARP00000022770 Danio rerio (zebra fish) ENSECAP00000005399 Equus caballus (horse) ENSGACP00000001255 Gymnopilus aculeatus (mushroom) ENSGALP00000023186 Gallus gallus (chicken) 185018 Hypsipyla robusta (cedar shoot borer) ENSP00000303468 Homo sapiens (human) ISCW000961-PA Ixodes scapularis (deer tick) ENSMODP00000000466 Monodelphis domestica (gray opossum) ENSMMUP00000020208 Macaca mulatta (rhesus monkey) ENSMUSP00000031077 Mus musculus (house mouse) XP_001606538.1 Nasonia vitripennis (wasp) ENSOANP00000010675 Ornithorynchus anatinus (platypus) ENSORLP00000024779 Oryzias latipes (japanese killifish) PHUM001810-PA Pediculus humanus (human body louse) PP26233 Pristionchus pacificus (nematode) ENSPPYP00000016365 Pongo pygmaeus (orangutan) ENSPTRP00000027482 Pan troglodytes (chimpanzee) ENSRNOP00000051233 Rattus norvegicus (norway rat) XP_001178580.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001194790.1 Strongylocentrotus purpuratus (purple sea urchin) 28284 Trichoplax adhaerens (metazoa) XP_970334.2 Tribolium castaneum (red flour beetle) ENSTNIP00000009072 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000025275 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000002081 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36623 modMine - Data generated by the modENCODE project. • FBgn0033948 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11520 LH18262 ISCW000961 FBgn0221523 JGI_V11_43964 FBgn0141533 CPIJ013353 BGIBMGA009901 ACYPI008533 GB17573 AAEL004422 PB25370 PHUM439080 GLEAN_05649
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG12863 (Keleman et al., 2009.8.5, Accardo et al., 2004)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Research paper	Accardo et al., 2004, Bioinformatics 20(18): 3293--3301 A computational search for box C/D snoRNA genes in the Drosophila melanogaster genome. [FBrf0187185]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2009.5.5, BDGP_2009_0507.GenExel.xml BDGP_2009_0507.GenExel.xml [FBrf0207859] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]