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Gene Dmel\HPS1

General Information
Symbol	Dmel\HPS1	Species	D. melanogaster
Name	Hermansky-Pudlak Syndrome 1 ortholog	Annotation symbol	CG12855
Feature type	protein_coding_gene	FlyBase ID	FBgn0033973
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	51C5-51C5	Sequence location	2R:10,742,934..10,745,007 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Hermansky-Pudlak Syndrome 1 ortholog is referred to in FlyBase by the symbol Dmel\HPS1 (CG12855, FBgn0033973). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Hermansky-Pudlak syndrome 1 protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval fat body, larval/adult salivary gland. Comments on Affy2 ProbeSet: ProbeSet 1627118_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of HPS1. Gene sequence location is 2R:10742934..10745007.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 51C5-51C5   Limits computationally determined from genome sequence between P{lacW}Rpn6k00103 and P{PZ}chn02064
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\HPS1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) HPS1-RA FBtr0087449  NM_137153   2074   596
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein HPS1-PA   FBpp0086579   66.7   596   6.35     NP_610997   AAF58194
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Hermansky-Pudlak syndrome 1 protein (IPR026053)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA538586   AE013599 AAF58194   AI516828   AI519606   AW941055   AY058469 AAL13698   BF488780   BI567790   BI583621   BI586137   BI588909   BI634926   CA806876   CA807386   CK131949   CK661300   CO279499   CO292707   CO293312   CO304804   CO325079   CO325313   CO328336   CO330246   EC198308   EC200940   EC201234   EC204914   EC221949   EC226136   EC258824
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7K3N1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval fat body, larval/adult salivary gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    122.075 Larval Midgut    53.5 Larval Hindgut    54 Larval Malpighian Tubules    91 Larval Fat Body    124.2 Larval Salivary Gland    100 Larval Trachea    56.25 Larval Carcass    58.75 Adult Head    153.1 Adult Eye    181.775 Adult Brain    380.8 Adult Thoracic-Abdominal Ganglion    248.5 Adult Crop    69.7 Adult Midgut    59.9 Adult Hindgut    54.7 Adult Malpighian Tubules    64.1 Adult Fat Body    91.5 Adult Salivary Gland    100.5 Adult Heart    72.3 Adult VirginFemale Spermatheca    87.3 Adult InseminatedFemale Spermatheca    76.7 Adult Ovary    72.2 Adult Testis    33.1 Adult Male Accessory Gland    65.8 Adult Carcass    58.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    153.1   NA  Eye    181.775   NA  Brain    380.8   122.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    248.5   NA  Crop    69.7   53.5  Midgut    59.9   54  Hindgut    54.7   91  Malpighian Tubules    64.1   124.2  Fat Body    91.5   100  Salivary Gland    100.5   NA  Heart    72.3   56.25  Trachea    NA   NA  VirginFemale Spermatheca    87.3   NA  InseminatedFemale Spermatheca    76.7   NA  Ovary    72.2   NA  Testis    33.1   NA  Male Accessory Gland    65.8   58.75  Carcass    58.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    3 central nervous system, larvae L3    4 central nervous system, pupae P8    11 head, virgin 1-day female    5 head, virgin 4-day female    6 head, virgin 20-day female    7 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    10 head, mated 4-day male    9 head, mated 20-day male    11 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    5 carcass, larvae L3 wandering    3 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    6 ovary, mated 4-day female    6 testis, mated 4-day male    2 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    4 embryo 08-10hr    6 embryo 10-12hr    9 embryo 12-14hr    8 embryo 14-16hr    12 embryo 16-18hr    7 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    8 larva L2    6 larva L3 12hr old    3 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    7 white prepupae new    8 white prepupae 12hr    8 white prepupae 24hr    10 pupae 2d postWPP    13 pupae 3d postWPP    7 pupae 4d postWPP    5 adult male 01day    6 adult male 05day    7 adult male 30day    8 adult female 01day    5 adult female 05day    6 adult female 30day    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    6 embryonic 1182-4H    5 embryonic GM2    7 embryonic Kc167    4 embryonic S1    3 embryonic S3    5 leg disc CME L1    3 wing disc CME-W2    5 wing disc ML-DmD8    7 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    6 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    5 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    3 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    4 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    4 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    4 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_25 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033973 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12855-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 HPS1GD1205 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of HPS1 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of HPS1 Class Mutagen Stocks Known lesion HPS1GD1205 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes HPS1NIG.12855R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes HPS1t4.7 in vitro construct 0 --
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.12855R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
HPS1 - ATPsyn-γ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Atpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG10672 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG1444 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG1458 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG2064 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG2065 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG2199 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG2862 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG4169 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG4692 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG4747 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG4769 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG5447 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CG5728 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Chc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Chd64 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - CoIV anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Eb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - FK506-bp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Fer1HCH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Flo-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Gale anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Gp210 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Gαi anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Hel25E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - ImpL3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - MRP anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Mtor anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Mtpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Nop56 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Nopp140 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Nup358 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Nup75 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Nup98-96 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Ost48 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Ote anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - PH4αEFB anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Pen anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Prx3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Rcc1 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) HPS1 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - RpS10b anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Rpb8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Su(var)205 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - TER94 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Tango5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Tapδ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Tcp-1η anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - Vap-33-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - bor anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - chic anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - fax anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - kst anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - l(2)03709 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - l(2)37Cc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - mTerf3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - mod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - mus209 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - nop5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - porin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - prod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - sle anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - smt3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) HPS1 - α-Spec anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions HPS1 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033973 DroID - A comprehensive database of gene and protein interactions. • FBgn0033973 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36656
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QJS6V Dipteran inclusive ortholog search EOG6P2Q9J Insect inclusive ortholog search EOG67PW22 Arthropod inclusive ortholog search EOG6XPNX1 Metazoa inclusive ortholog search EOG69D31T
Orthologs in Drosophila Species (EOG6QJS6V)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\HPS1     Drosophila simulans   Dsim\GD11081 Y   Drosophila sechellia   Dsec\GM21576 Y   Drosophila erecta   Dere\GG20485 Y   Drosophila yakuba   Dyak\GE13616 Y   Drosophila ananassae   Dana\GF12824 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11858 Y   Drosophila persimilis   Dper\GL11251 Y   Drosophila willistoni   Dwil\GK22171 Y   Drosophila virilis   Dvir\GJ20765 Y   Drosophila mojavensis   Dmoj\GI20585 Y   Drosophila grimshawi   Dgri\GH22790 Y
Orthologs in non-Drosophila Dipterans (EOG6P2Q9J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012884   Anopheles gambiae Malaria mosquito  Agam\AGAP011210   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017811
Orthologs in non-Dipteran Insects (EOG67PW22)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47076   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001499   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12698   Atta cephalotes Leafcutter ant  Acep\ACEP18514   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19455   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19266   Linepithema humile Argentine ant  Lhum\LH10697   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20711   Solenopsis invicta Red fire ant  Sinv\SINV22287   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009278   Bombyx mori Silkmoth  Bmor\BGIBMGA011478   Pediculus humanus Human body louse  Phum\PHUM202080   Tribolium castaneum Red flour beetle  Tcas\TC001237
Orthologs in non-Insect Arthropods (EOG6XPNX1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_323149   Ixodes scapularis Deer tick  Isca\ISCW003346
Orthologs in non-Arthropod Metazoa (EOG69D31T)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025781gn   Danio rerio Zebrafish  Drer\hps1   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000026342   Gallus gallus Domestic chicken  Ggal\HPS1   Mus musculus House mouse  Mmus\ENSMUSG00000025188   Rattus norvegicus Norway rat  Rnor\Hps1   Homo sapiens Human  Hsap\HPS1
Human Orthologs (1)
Gene OMIM HGNC Hsap\HPS1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11081 Drosophila sechellia Dsec\GM21576 Drosophila erecta Dere\GG20485 Drosophila yakuba Dyak\GE13616 Drosophila ananassae Dana\GF12824 Drosophila pseudoobscura pseudoobscura Dpse\GA11858 Drosophila persimilis Dper\GL11251 Drosophila willistoni Dwil\GK22171 Drosophila virilis Dvir\GJ20765 Drosophila mojavensis Dmoj\GI20585 Drosophila grimshawi Dgri\GH22790
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v5639 w1118; P{GD1205}v5639 v5641 w1118; P{GD1205}v5641
Genomic Clones ( 1 )
	BACR03K23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 29 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH27401
Other clones	DPiM_GH27401
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24422 LD18151 LD39251 LP13063 LP20690 RH22278 RH25896 RH30367 RH38374 RH39195
Other clones	20911 35740 67500 73340 123341 191881 214569.61 EK134848 EK195538 EK196108 EK200807 EK202546 EK246253 EK294814 EP09023 ESG015b.E21_G05 ESG017c.E21.4_H04
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0033973 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36656
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: HPS1 HPS (Lee et al., 2009) Source for identity of: HPS CG12855 (Radford et al., 2005)
Source for database merge of
Additional comments
Other Comments
	S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006) Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; decreased expression in per01, tim01 and ClkJrk background. (Claridge-Chang et al., 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137153 RefSeq (Proteins) • NP_610997 DDBJ / EMBL / GenBank • AAF58194 AAL13698 AI516828 AW941055 AY058469 Entrez Gene - A searchable database of RefSeq genes. • 36656 UniProtKB/TrEMBL • Q7K3N1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Hermansky-Pudlak syndrome 1 protein (IPR026053)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0033973 DroID - A comprehensive database of gene and protein interactions. • FBgn0033973 DRSC - Results from RNAi screens. • FBgn0033973 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033973 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12855-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033973 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36656 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36656 modMine - Data generated by the modENCODE project. • FBgn0033973
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG12855 (Falcon-Perez et al., 2007, Radford et al., 2005, Claridge-Chang et al., 2001, Stroschein-Stevenson et al., 2006, Lee et al., 2009) dHPS1 (Lee et al., 2009) HPS (Japanese National Institute of Genetics, 2012.5.21) HPS1
Name Synonym	Hermansky-Pudlak Syndrome 1 ortholog   HPS
Secondary FlyBase IDs
References ( 13 )
Research paper	Lee et al., 2009, Nat. Cell Biol. 11(9): 1150--1156 Silencing by small RNAs is linked to endosomal trafficking. [FBrf0208810] Falcon-Perez et al., 2007, Traffic 8(2): 154--168 The Drosophila Pigmentation Gene pink (p) Encodes a Homologue of Human Hermansky-Pudlak Syndrome 5 (HPS5). [FBrf0192474] Stroschein-Stevenson et al., 2006, PLoS Biol. 4(1): e4 Identification of Drosophila gene products required for phagocytosis of Candida albicans. [FBrf0191376] Radford et al., 2005, Genetics 170(4): 1737--1745 Drosophila ERCC1 Is Required for a Subset of MEI-9-Dependent Meiotic Crossovers. [FBrf0187655] Claridge-Chang et al., 2001, Neuron 32(4): 657--671 Circadian regulation of gene expression systems in the Drosophila head. [FBrf0141689]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]