Gene model reviewed during 5.44
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgant1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pgant1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
FlyBase curator comment: "l(2)35Aa" (FBgn0001970, Pgant35A, CG7480) is also referred to in FBrf0151358 as "dGalNAc-T1", but "l(2)35Aa" is not the same gene as the gene with the valid symbol "GalNAc-T1" in FlyBase, which is FBgn0034025, CG8182 described in FBrf0130686 (accession number AF218236).
Source for identity of GalNAc-T1 CG8182 was sequence comparison ( date:000916 ).