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Gene Dmel\bdg

General Information
Symbol	Dmel\bdg	Species	D. melanogaster
Name	bedraggled	Annotation symbol	CG8291
Feature type	protein_coding_gene	FlyBase ID	FBgn0034049
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	52D2-52D2	Sequence location	2R:11,810,545..11,819,440 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene bedraggled is referred to in FlyBase by the symbol Dmel\bdg (CG8291, FBgn0034049). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: neurotransmitter transporter activity. There is experimental evidence that it is involved in the biological process: R3/R4 cell fate commitment. 11 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; antennal disc; eye photoreceptor cell; ommatidium. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Sodium:neurotransmitter symporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult hindgut, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1639040_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of bdg. Gene sequence location is 2R:11810545..11819440.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 52D2-52D2   Limits computationally determined from genome sequence between P{lacW}l(2)k02205k02205&P{PZ}sli05248 and P{lacW}ATPCLk09217
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\bdg for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) bdg-RA FBtr0087298  NM_137220   4407   1331 bdg-RB FBtr0087299  NM_166121   4914   1331 bdg-RC FBtr0087300  NM_176181   4620   1331 bdg-RD FBtr0340017     4404   1330
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein bdg-PA   FBpp0086433   146.7   1331   6.75     NP_611064   AAF58096 bdg-PB   FBpp0086434   146.7   1331   6.75     NP_725499   AAM70967 bdg-PC   FBpp0086435   146.7   1331   6.75     NP_788361   AAO41388 bdg-PD   FBpp0309031   146.5   1330   6.75
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sodium:neurotransmitter symporter (IPR000175)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202121   AA821102   AA950142   AA951926   AE013599 AAF58096   AE013599 AAM70967   AE013599 AAO41388   AI532783   AI534149   AI534226   AI534231   AI546680   AI546691   AW944472   AY118652 AAM50021   BF486731   BF494258   BF499995   BF504603   BG637740   BG639813   BH840731   BI579737   BI608223   BI628445   BI632865   BI639792   CA806523   CA806592   CA806830   CA807101   CO266911   CO273643   CO281586   CO292106   CO301137   CO306756   CO310640   CO326597   CO339496   CZ482397   CZ489778   EC074198   EC084889   EC209387   EC212410   EC221994   EC237859   EC254419   EC255526   ES693805   ES693871   EV587799   EV590608   EV591769
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q0E961 Q8MSR0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference adult stage   adult head   (Romero-Calderon et al., 2007) adult thorax   (Romero-Calderon et al., 2007) Comment:Thorax and abdomen assayed together. adult abdomen   (Romero-Calderon et al., 2007) Comment:Thorax and abdomen assayed together.
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult hindgut, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    88.525 Larval Midgut    49.8 Larval Hindgut    75.5 Larval Malpighian Tubules    51.1 Larval Fat Body    31.6 Larval Salivary Gland    28.1 Larval Trachea    34.7 Larval Carcass    68.375 Adult Head    44.9 Adult Eye    37.85 Adult Brain    57.8 Adult Thoracic-Abdominal Ganglion    58.5 Adult Crop    84.6 Adult Midgut    45.9 Adult Hindgut    380.1 Adult Malpighian Tubules    33.8 Adult Fat Body    22.3 Adult Salivary Gland    25 Adult Heart    36.575 Adult VirginFemale Spermatheca    18.1 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    61.1 Adult Testis    182.7 Adult Male Accessory Gland    38.9 Adult Carcass    46.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    44.9   NA  Eye    37.85   NA  Brain    57.8   88.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    58.5   NA  Crop    84.6   49.8  Midgut    45.9   75.5  Hindgut    380.1   51.1  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   28.1  Salivary Gland    no informative data   NA  Heart    36.575   34.7  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    61.1   NA  Testis    182.7   NA  Male Accessory Gland    no informative data   68.375  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male  (27) accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male  27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    20 central nervous system, larvae L3    9 central nervous system, pupae P8    5 head, virgin 1-day female    3 head, virgin 4-day female    3 head, virgin 20-day female    3 head, mated 1-day female    3 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    5 head, mated 4-day male    4 head, mated 20-day male    5 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    6 digestive system, 4-day adult    4 digestive system, 20-day adult    6 fat body, larvae L3 wandering    1 fat body, white prepupae    6 fat body, pupae P8    9 carcass, larvae L3 wandering    10 carcass, 1-day adult    3 carcass, 4-day adult    3 carcass, 20-day adult    4 ovary, virgin 4-day female    11 ovary, mated 4-day female    11 testis, mated 4-day male    27 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr  (31) embryo 04-06hr  (42) embryo 06-08hr  (45) embryo 08-10hr  (34) embryo 10-12hr  (27) embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr  31 embryo 04-06hr  (42) embryo 06-08hr  (45) embryo 08-10hr  (34) embryo 10-12hr  27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    31 embryo 04-06hr    42 embryo 06-08hr    45 embryo 08-10hr    34 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    17 embryo 16-18hr    16 embryo 18-20hr    13 embryo 20-22hr    8 embryo 22-24hr    8 larva L1    6 larva L2    5 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    20 white prepupae new    20 white prepupae 12hr    23 white prepupae 24hr    20 pupae 2d postWPP    18 pupae 3d postWPP    11 pupae 4d postWPP    16 adult male 01day    15 adult male 05day    18 adult male 30day    18 adult female 01day    8 adult female 05day    9 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (49) Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (49) Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    49 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    9 embryonic Kc167    11 embryonic S1    17 embryonic S3    8 leg disc CME L1    8 wing disc CME-W2    13 wing disc ML-DmD8    11 wing disc ML-DmD9    11 wing disc ML-DmD16-c3    17 wing disc ML-DmD21    11 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    12 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    16 tumorous blood cells mbn2    19 ovary fGS/OSS    24 ovary OSC    10 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034049 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8291-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4Act.PU bdgScer\UAS.cRa lethal, with Scer\GAL4hs.PB bdgScer\UAS.cRa lethal | recessive bdg36 bdg90 bdg164 viable, with Scer\GAL4pnr-MD237 bdgGD2018 Other Phenotypes Allele flightless bdg36 bdg164 locomotor behavior defective | adult stage bdg36 bdg164 planar polarity defective bdgGMREP planar polarity defective, with Scer\GAL4GMR.PF bdgScer\UAS.cRa uncoordinated | adult stage bdg36 bdg164 Phenotype manifest in Allele antennal disc bdg90 eye disc bdg90 eye photoreceptor cell bdgGMREP bdg164 eye photoreceptor cell, with Scer\GAL4GMR.PF bdgScer\UAS.cRa eye photoreceptor cell | somatic clone bdg90 ommatidium bdgGMREP bdg164 ommatidium, with Scer\GAL4GMR.PF bdgScer\UAS.cRa ommatidium | somatic clone bdg90
Classical Alleles ( 7 )
For All Classical Alleles Show
Allele of bdg Class Mutagen Stocks Known lesion bdge04631 piggyBac transposase 1 -- bdgKG07083 P-element activity 1 Yes bdg164 Delta2-3 0 Yes bdg36 Delta2-3 0 Yes bdg90 Delta2-3 0 Yes bdgf07025 piggyBac transposase 0 -- bdgGMREP 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of bdg Class Mutagen Stocks Known lesion bdgGD2018 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes bdgKK105846 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes bdgScer\UAS.cRa in vitro construct - regulatory fusion 0 Yes bdgt7.4 in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7138 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK105846} NA P{UAS-bdg.R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}sliEP2577 NA P{Mae-GMR.EP}bdgGMREP NA insertion of enhancer trap P{lacW}l(2)SH1673SH1673 No P{PZ}sli05248 No miscellaneous insertions P{SUPor-P}bdgKG07083 NA PBac{RB}bdge04631 NA PBac{WH}bdgf07025 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
R3/R4 cell fate commitment inferred from genetic interaction with dgo (Rawls et al., 2007) inferred from genetic interaction with dsh (Rawls et al., 2007) inferred from genetic interaction with stan (Rawls et al., 2007) inferred from genetic interaction with Vang (Rawls et al., 2007) inferred from mutant phenotype (Rawls et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
neurotransmitter:sodium symporter activity inferred from electronic annotation with InterPro:IPR000175 (FlyBase Curators et al., 2004-) neurotransmitter transporter activity inferred from sequence or structural similarity with DAT (Romero-Calderon et al., 2007) inferred from sequence or structural similarity with UniProtKB:P23978 (FlyBase, 1992-)
Biological Process
CV term Evidence References
neurotransmitter transport inferred from sequence or structural similarity with DAT (Romero-Calderon et al., 2007)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000175 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions bdg allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62474 DroID - A comprehensive database of gene and protein interactions. • FBgn0034049 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36747
Orthologs
OrthoDB Orthologs (33) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NW04N Dipteran inclusive ortholog search EOG6C2HJK Insect inclusive ortholog search EOG6THTNX Arthropod inclusive ortholog search EOG69CNPH Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6NW04N)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\bdg     Drosophila simulans   Dsim\GD25588 Y   Drosophila sechellia   Dsec\GM20111 Y   Drosophila erecta   Dere\GG22323 Y   Drosophila yakuba   Dyak\GE14119 Y   Drosophila ananassae   Dana\GF13338 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20961 Y   Drosophila persimilis   Dper\GL16261 Y   Drosophila willistoni   Dwil\GK19541 Y   Drosophila virilis   Dvir\GJ20902 Y   Drosophila mojavensis   Dmoj\GI21300 Y   Drosophila grimshawi   Dgri\GH20963 Y
Orthologs in non-Drosophila Dipterans (EOG6C2HJK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006800   Anopheles gambiae Malaria mosquito  Agam\AGAP012290   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ010535
Orthologs in non-Dipteran Insects (EOG6THTNX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47438   Apis mellifera Western honey bee  Amel\GB47439   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004544   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004543   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14562   Atta cephalotes Leafcutter ant  Acep\ACEP10639   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17514   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13685   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13686   Linepithema humile Argentine ant  Lhum\LH21943   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14797   Solenopsis invicta Red fire ant  Sinv\SINV22803   Acyrthosiphon pisum Pea aphid  Apim\ACYPI010163   Bombyx mori Silkmoth  Bmor\BGIBMGA011081   Pediculus humanus Human body louse  Phum\PHUM079960   Tribolium castaneum Red flour beetle  Tcas\TC000366
Orthologs in non-Insect Arthropods (EOG69CNPH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Surf4   Ixodes scapularis Deer tick  Isca\ISCW010698
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25588 Drosophila sechellia Dsec\GM20111 Drosophila erecta Dere\GG22323 Drosophila yakuba Dyak\GE14119 Drosophila ananassae Dana\GF13338 Drosophila pseudoobscura pseudoobscura Dpse\GA20961 Drosophila persimilis Dper\GL16261 Drosophila willistoni Dwil\GK19541 Drosophila virilis Dvir\GJ20902 Drosophila mojavensis Dmoj\GI21300 Drosophila grimshawi Dgri\GH20963
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	14160 y1 w67c23; P{SUPor-P}bdgKG07083
Harvard	- PBac{RB}bdge04631
VDRC	v44375 w1118; P{GD2018}v44375
Genomic Clones ( 1 )
	BACR07M03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 43 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD06851
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02703 AT06193 AT14782 AT21241 GM09715 LD28685 LD32837 RE73814 RH12413 RH56853 SD04401 SD06667 SD10015 SD10418 SD22469 SD26756
Other clones	11513 37006 42702 57972 71289 145277 214213.73 214535.80 Dmel_neb_011323_0340_2636 Dmel_neb_011801_0352_0559 Dmel_neb_013854_0209_0334 EK111722 EK147916 EK157615 EK180223 EK199215 EK222206 EK252213 EP02127 EP04259 ESG013d.E21_B05 ESG014a.E21_D11 ESG015b.E21_A05 ESG016b.E21_C02 LD02241 SD06837
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034049 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36747
Antibody Information
Other Information
Discoverer
Etymology
	The gene is named "bedraggled" for the appearance of mutant flies after they get stuck in the food due to defects in motor coordination. (Rawls et al., 2007)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: bdg CG8291 (Rawls et al., 2007)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137220 NM_166121 NM_176181 RefSeq (Proteins) • NP_611064 NP_725499 NP_788361 DDBJ / EMBL / GenBank • AAF58096 AAM50021 AAM70967 AAO41388 AI534231 AW944472 AY118652 BH840731 CZ482397 CZ489778 Entrez Gene - A searchable database of RefSeq genes. • 36747 UniProtKB/TrEMBL • Q0E961 Q8MSR0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sodium:neurotransmitter symporter (IPR000175)
Linkouts
	BioGRID - A database of protein and genetic interactions • 62474 DroID - A comprehensive database of gene and protein interactions. • FBgn0034049 DRSC - Results from RNAi screens. • FBgn0034049 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034049 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8291-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034049 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36747 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36747 modMine - Data generated by the modENCODE project. • FBgn0034049
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	bdg (Rawls et al., 2007) CG8291 (Rawls et al., 2007, Huh et al., 2007, Quinones-Coello, 2007, Romero-Calderon et al., 2007, Vinci et al., 2008, Miller et al., 2008, Anaka et al., 2008, Thimgan et al., 2006, Pauli et al., 2010, Keleman et al., 2009.8.5)
Name Synonym	bedraggled (Rawls et al., 2007) CG8291
Secondary FlyBase IDs
References ( 25 )
Generate a list of	All references relating to this gene ( 25 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...