The gene bedraggled is referred to in FlyBase by the symbol Dmel\bdg (CG8291, FBgn0034049). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:15923040..15931935. Its molecular function is described by: L-amino acid transmembrane transporter activity; amino acid:sodium symporter activity; neurotransmitter:sodium symporter activity; neurotransmitter transmembrane transporter activity. It is involved in the biological process described with: glycine import across plasma membrane; R3/R4 cell fate commitment; sodium ion transmembrane transport; neurotransmitter transport. 15 alleles are reported. The phenotypes of these alleles manifest in: antennal disc; eye disc; ommatidium; eye photoreceptor cell. The phenotypic classes of alleles include: abnormal planar polarity; flightless; lethal; viable; uncoordinated; abnormal locomotor behavior. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages.
Please see the JBrowse view of Dmel\bdg for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bdg using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: Thorax and abdomen assayed together.
Comment: Thorax and abdomen assayed together.
Expression pattern inferred from unspecified enhancer trap line.
JBrowse - Visual display of RNA-Seq signals
View Dmel\bdg in JBrowseThe gene 'ToolKit' contains a set of key genetic reagents that can be used to study a gene. A single reagent for each category is chosen based on frequency of usage, and stock availability. Click "See all" to view all the reagents for the category.
Category | Common alleles (# stocks) |
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Classical and Insertion Alleles | |
Loss of function allele | |
Amorphic allele | |
Fluorescently-tagged allele | |
Transgenic Constructs | |
UAS RNAi | |
UAS wild-type cDNA | |
Untagged genomic rescue | |
Fluorescently-tagged genomic rescue | |
Aberrations | |
Deficiency | |
Duplication |
2-76
2-80.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: bdg CG8291
The gene is named "bedraggled" for the appearance of mutant flies after they get stuck in the food due to defects in motor coordination.