A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\unc-104

General Information
SymbolDmel\unc-104SpeciesD. melanogaster
Nameunc-104Annotation symbolCG8566
Feature typeprotein_coding_geneFlyBase IDFBgn0034155
Gene Model StatusCurrent Stock availability 15 publicly available
Also Known Asimac, Klp53D, DmKlp53D
Genomic Location
Chromosome (arm)2RRecombination map
Cytogenetic map53D6-53D7Sequence location2R:12,639,008..12,660,002 [-]

Genomic Maps

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modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene unc-104 is referred to in FlyBase by the symbol Dmel\unc-104 (CG8566, FBgn0034155). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: microtubule motor activity. There is experimental evidence that it is involved in the biological process: synaptic vesicle maturation; vesicle transport along microtubule; axon guidance; anterograde synaptic vesicle transport; synaptic vesicle transport; neuromuscular junction development; vesicle-mediated transport; larval locomotory behavior. 28 alleles are reported. The phenotypes of these alleles are annotated with: bouton; terminal button; embryonic/larval neuromuscular junction; ISNb; synapse; synaptic vesicle. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Forkhead-associated (FHA) domain; Kinesin protein 1B; Kinesin, motor domain; Kinesin, motor region, conserved site; Kinesin-like; Pleckstrin homology domain; Pleckstrin homology-type; SMAD/FHA domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval Malpighian tubules, adult heart, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637684_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of unc-104. Gene sequence location is 2R:12639008..12660002.

External Summaries
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Description
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What does this section not display?
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FB2012_01
References
Sequence features
FB2011_10
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
53D6-53D7  
Limits computationally determined from genome sequence between P{PZ}Sema-2a03021&P{PZ}Cdk405428 and P{EP}BEST:SD02913EP2148&P{lacW}Dekk09907  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
53D-53D  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\unc-104 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0087080 FBtr0303024 FBtr0091496 FBtr0112382 FBtr0087021 FBtr0300043 FBtr0113088 FBtr0304679 FBtr0304680 FBtr0113089 FBtr0087079 FBtr0305319 FBtr0305318 FBtr0113087 FBtr0087078 FBtr0087023 FBpp0086228 FBpp0292143 FBpp0100040 FBpp0111297 FBpp0086172 FBpp0112001 FBpp0293221 FBpp0086227 FBpp0112000 FBpp0293222 FBpp0112002 FBpp0289320 FBpp0293862 FBpp0293861 FBpp0086226 FBpp0086174 FBti0042349 FBti0131720 FBti0078464 FBti0127543 FBti0042969 FBti0051326 FBti0067419 FBti0042460 FBti0023224
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0113087
  7234
  1670
FBtr0113088
  7381
  1670
FBtr0087079
  7588
  1739
FBtr0113089
  7423
  1684
FBtr0304679
 
  7396
  1675
FBtr0304680
 
  7414
  1681
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0112000  
189.3  
1670  
6.09  
FBpp0112001  
189.3  
1670  
6.09  
FBpp0086227  
197.0  
1739  
6.04  
FBpp0112002  
190.8  
1684  
6.17  
FBpp0293221  
189.6  
1675  
6.01  
 
 
FBpp0293222  
190.6  
1681  
6.17  
 
 
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view Acp53C14c-RB Acp53C14c-RA CG34189-RA CG5267-RA CG42392-RA unc-104-RC unc-104-RG unc-104-RE unc-104-RF unc-104-RD CG5348-RC CG5348-RB unc-104-RB Sod2-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0034155


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0034155
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0034155 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (559)
embryo 02-04hr
 (190)
embryo 04-06hr
 (243)
embryo 06-08hr
 (295)
embryo 08-10hr
 (372)
embryo 10-12hr
 (434)
embryo 12-14hr
 (714)
embryo 14-16hr
 (828)
embryo 16-18hr
 (1335)
embryo 18-20hr
 (1939)
embryo 20-22hr
 (2331)
embryo 22-24hr
 (2939)
larva L1
 (2316)
larva L2
 (896)
larva L3 12hr old
 (365)
larva L3 puffstage 1-2
 (234)
larva L3 puffstage 3-6
 (581)
larva L3 puffstage 7-9
 (1000)
white prepupae new
 (1430)
white prepupae 12hr
 (1418)
white prepupae 24hr
 (1692)
pupae 2d postWPP
 (1829)
pupae 3d postWPP
 (1846)
pupae 4d postWPP
 (1748)
adult male 01day
 (2042)
adult male 05day
 (2048)
adult male 30day
 (1974)
adult female 01day
 (1028)
adult female 05day
 (800)
adult female 30day
 (800)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 (1939)
embryo 20-22hr
 (2331)
embryo 22-24hr
 (2939)
larva L1
 (2316)
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 1430
white prepupae 12hr
 1418
white prepupae 24hr
 (1692)
pupae 2d postWPP
 (1829)
pupae 3d postWPP
 (1846)
pupae 4d postWPP
 (1748)
adult male 01day
 (2042)
adult male 05day
 (2048)
adult male 30day
 (1974)
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0034155 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (559)
embryo 02-04hr
 (190)
embryo 04-06hr
 (243)
embryo 06-08hr
 (295)
embryo 08-10hr
 (372)
embryo 10-12hr
 (434)
embryo 12-14hr
 (714)
embryo 14-16hr
 (828)
embryo 16-18hr
 (1335)
embryo 18-20hr
 (1939)
embryo 20-22hr
 (2331)
embryo 22-24hr
 (2939)
larva L1
 (2316)
larva L2
 (896)
larva L3 12hr old
 (365)
larva L3 puffstage 1-2
 (234)
larva L3 puffstage 3-6
 (581)
larva L3 puffstage 7-9
 (1000)
white prepupae new
 (1430)
white prepupae 12hr
 (1418)
white prepupae 24hr
 (1692)
pupae 2d postWPP
 (1829)
pupae 3d postWPP
 (1846)
pupae 4d postWPP
 (1748)
adult male 01day
 (2042)
adult male 05day
 (2048)
adult male 30day
 (1974)
adult female 01day
 (1028)
adult female 05day
 (800)
adult female 30day
 (800)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 1939
embryo 20-22hr
 2331
embryo 22-24hr
 (2939)
larva L1
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 1430
white prepupae 12hr
 1418
white prepupae 24hr
 1692
pupae 2d postWPP
 1829
pupae 3d postWPP
 1846
pupae 4d postWPP
 1748
adult male 01day
 2042
adult male 05day
 2048
adult male 30day
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 559
embryo 02-04hr
 
 190
embryo 04-06hr
 
 243
embryo 06-08hr
 
 295
embryo 08-10hr
 
 372
embryo 10-12hr
 
 434
embryo 12-14hr
 
 714
embryo 14-16hr
 
 828
embryo 16-18hr
 
 1335
embryo 18-20hr
 
 1939
embryo 20-22hr
 
 2331
embryo 22-24hr
 
 2939
larva L1
 
 2316
larva L2
 
 896
larva L3 12hr old
 
 365
larva L3 puffstage 1-2
 
 234
larva L3 puffstage 3-6
 
 581
larva L3 puffstage 7-9
 
 1000
white prepupae new
 
 1430
white prepupae 12hr
 
 1418
white prepupae 24hr
 
 1692
pupae 2d postWPP
 
 1829
pupae 3d postWPP
 
 1846
pupae 4d postWPP
 
 1748
adult male 01day
 
 2042
adult male 05day
 
 2048
adult male 30day
 
 1974
adult female 01day
 
 1028
adult female 05day
 
 800
adult female 30day
 
 800
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0034155


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0034155
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval Malpighian tubules, adult heart, adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0034155 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1134.5
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 
 1315.9
Adult Eye
 
 1316.125
Adult Brain
 
 2494.7
Adult Thoracic-Abdominal Ganglion
 
 2911.8
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1134.5)
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 (1315.9)
Adult Eye
 (1316.125)
Adult Brain
 (2494.7)
Adult Thoracic-Abdominal Ganglion
 (2911.8)
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 (1134.5)
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 (1315.9)
Adult Eye
 (1316.125)
Adult Brain
 (2494.7)
Adult Thoracic-Abdominal Ganglion
 (2911.8)
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1134.5
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 
 1315.9
Adult Eye
 
 1316.125
Adult Brain
 
 2494.7
Adult Thoracic-Abdominal Ganglion
 
 2911.8
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0034155 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1134.5
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 
 1315.9
Adult Eye
 
 1316.125
Adult Brain
 
 2494.7
Adult Thoracic-Abdominal Ganglion
 
 2911.8
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1134.5)
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 (1315.9)
Adult Eye
 (1316.125)
Adult Brain
 (2494.7)
Adult Thoracic-Abdominal Ganglion
 (2911.8)
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 1134.5
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 1315.9
Adult Eye
 1316.125
Adult Brain
 (2494.7)
Adult Thoracic-Abdominal Ganglion
 (2911.8)
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1134.5
Larval Midgut
 
 51.3
Larval Hindgut
 
 61.4
Larval Malpighian Tubules
 
 159
Larval Fat Body
 
 47.8
Larval Salivary Gland
 
 55.3
Larval Trachea
 
 70.325
Larval Carcass
 
 61.225
Adult Head
 
 1315.9
Adult Eye
 
 1316.125
Adult Brain
 
 2494.7
Adult Thoracic-Abdominal Ganglion
 
 2911.8
Adult Crop
 
 56.8
Adult Midgut
 
 86.6
Adult Hindgut
 
 75.8
Adult Malpighian Tubules
 
 70.2
Adult Fat Body
 
 62.4
Adult Salivary Gland
 
 92
Adult Heart
 
 121.65
Adult VirginFemale Spermatheca
 
 77.6
Adult InseminatedFemale Spermatheca
 
 73.6
Adult Ovary
 
 34.1
Adult Testis
 
 12.9
Adult Male Accessory Gland
 
 502
Adult Carcass
 
 153.9
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 1315.9
 
NA 
Eye
 
 1316.125
 
NA 
Brain
 
 2494.7
 
1134.5 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 2911.8
 
NA 
Crop
 
 56.8
 
51.3 
Midgut
 
 86.6
 
61.4 
Hindgut
 
 75.8
 
159 
Malpighian Tubules
 
 70.2
 
47.8 
Fat Body
 
 62.4
 
55.3 
Salivary Gland
 
 92
 
NA 
Heart
 
 121.65
 
70.325 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 77.6
 
NA 
InseminatedFemale Spermatheca
 
 73.6
 
NA 
Ovary
 
 34.1
 
NA 
Testis
 
 12.9
 
NA 
Male Accessory Gland
 
 502
 
61.225 
Carcass
 
 153.9

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
dense core granule & axon (with unc-104O1.2)
dense core granule & axon (with unc-104O3.1)
dense core granule & axon (with unc-104P350)
hide Classical Alleles ( 21 )
For All Classical Alleles Show

Allele of unc-104ClassMutagenStocksKnown lesion
unc-104d112042 --
unc-104f03580
1 --
unc-104MB05021
1 --
unc-104MB10763
1 --
unc-104P3501 Yes
unc-104R7571 Yes
unc-1041020 Yes
unc-1041160 Yes
unc-1041600 Yes
unc-1041700 Yes
unc-1041720 Yes
unc-104500 Yes
unc-104520 Yes
unc-104760 Yes
unc-104C6740 Yes
unc-104f02071
0 --
unc-104O1.2hypomorphic allele - genetic evidence0 --
unc-104O3.1hypomorphic allele - genetic evidence0 --
unc-104R18290 Yes
unc-104R4030 Yes
unc-104R7670 Yes
hide Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show

Allele of unc-104ClassMutagenStocksKnown lesion
unc-104Scer\UAS.RVB.T:Avic\GFP-S65T3 Yes
unc-104GD135262 Yes
unc-104GD164062 Yes
unc-104HM051621 Yes
unc-104dsRNA.cGa0 Yes
unc-104GMR.PB0 Yes
unc-104Scer\UAS.cPCa0 Yes
hide Aneuploid Aberrations
Disrupted in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
characterization construct
Insertions
Type of insertions
Name
Expression data
insertion of mobile activating element
miscellaneous insertions
insertion of enhancer trap binary system
hide Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
hide Terms Based on Experimental Evidence ( 9 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProtKB)
Cellular Component
CV term
References
inferred from mutant phenotype
(assigned by UniProtKB)
hide Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term
References
inferred from sequence or structural similarity with UniProtKB:O43896
Biological Process ( 0 terms)
Cellular Component
CV term
References
inferred from sequence or structural similarity with UniProtKB:O43896
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
unc-104 allele
Gene
References
hide External Data
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 15 )
Bloomington
Harvard
VDRC
hide Genomic Clones ( 2 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 38 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for identity of: unc-104 CG8566
Source for database merge of
Additional comments
Source for identity of unc-104 CG8566 was sequence comparison (date:000607).
hide Other Comments
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym
Name Synonym
unc-104
 
Secondary FlyBase IDs
hide References ( 43 )
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List References by type
hide Recent research papers ( 1 )
Rui et al., 2010, PLoS Genet. 6(11): e1001208
Sarcomere formation occurs by the assembly of multiple latent protein complexes. [FBrf0212444]
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All reviews listed in FlyBase were published before 2010