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Gene Dmel\CG6484

General Information
Symbol	Dmel\CG6484	Species	D. melanogaster
Name		Annotation symbol	CG6484
Feature type	protein_coding_gene	FlyBase ID	FBgn0034247
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	54C10-54C10	Sequence location	2R:13,469,512..13,471,514 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6484 (FBgn0034247). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: glucose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: General substrate transporter; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter; Sugar transporter, conserved site; Sugar/inositol transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut, virgin spermatheca, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, adult heart, adult fat body, inseminated spermatheca, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626734_at partially aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6484: 13 out of 14 probes fall into this exonic region. Gene sequence location is 2R:13469512..13471514.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN26784 HFA06991
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 54C10-54C10   Limits computationally determined from genome sequence between P{EP}MESR4EP386&P{EP}POSHEP1206 and P{PZ}l(2)1050510505
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6484 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6484-RA FBtr0086903  NM_137390   1587   465
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6484-PA   FBpp0086060   50.3   465   4.84     NP_611234   AAF57829
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sugar/inositol transporter (IPR003663) Sugar transporter, conserved site (IPR005829) Major facilitator superfamily domain, general substrate transporter (IPR016196) General substrate transporter (IPR005828) Major facilitator superfamily domain (IPR020846)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141222   AA141223   AE013599 AAF57829   AI390039   AW940827   AY058435 AAL13664   BI373236   CO176945   CO185785   CZ481523   EC058480   EC240541   EC260730   GH748796   GH750119   GH772504   GH786604   GH787249   GH798393   GH802340   GH816540   GH823933   GH828777   GH857027   GH865292   GH868220   GH871502   GH873100   GH886336   GH894362   GH894427   GH895102   GH903400   GH904769   GH929308   GH929340   GH938220   GH939859   GH942387   GH942415   GH942433
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7K3P6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034247    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034247 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034247 expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr  (162) embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr  (535) embryo 16-18hr  (776) embryo 18-20hr  (2330) embryo 20-22hr  (3524) embryo 22-24hr  (4181) larva L1  (2536) larva L2  (2448) larva L3 12hr old  (692) larva L3 puffstage 1-2  (528) larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new  (114) white prepupae 12hr  (153) white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP  (1075) adult male 01day  (6336) adult male 05day  (4298) adult male 30day  (3683) adult female 01day  (4471) adult female 05day  (1234) adult female 30day  (875) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr  (2330) embryo 20-22hr  (3524) embryo 22-24hr  (4181) larva L1  (2536) larva L2  (2448) larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day  (6336) adult male 05day  (4298) adult male 30day  (3683) adult female 01day  (4471) adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034247 expression level Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr  (162) embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr  (535) embryo 16-18hr  (776) embryo 18-20hr  (2330) embryo 20-22hr  (3524) embryo 22-24hr  (4181) larva L1  (2536) larva L2  (2448) larva L3 12hr old  (692) larva L3 puffstage 1-2  (528) larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new  114 white prepupae 12hr  (153) white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP  (1075) adult male 01day  (6336) adult male 05day  (4298) adult male 30day  (3683) adult female 01day  (4471) adult female 05day  (1234) adult female 30day  (875) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr  2330 embryo 20-22hr  (3524) embryo 22-24hr  (4181) larva L1  (2536) larva L2  2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day  (6336) adult male 05day  (4298) adult male 30day  (3683) adult female 01day  (4471) adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3 embryo 02-04hr    61 embryo 04-06hr    83 embryo 06-08hr    162 embryo 08-10hr    97 embryo 10-12hr    61 embryo 12-14hr    92 embryo 14-16hr    535 embryo 16-18hr    776 embryo 18-20hr    2330 embryo 20-22hr    3524 embryo 22-24hr    4181 larva L1    2536 larva L2    2448 larva L3 12hr old    692 larva L3 puffstage 1-2    528 larva L3 puffstage 3-6    90 larva L3 puffstage 7-9    40 white prepupae new    114 white prepupae 12hr    153 white prepupae 24hr    45 pupae 2d postWPP    48 pupae 3d postWPP    54 pupae 4d postWPP    1075 adult male 01day    6336 adult male 05day    4298 adult male 30day    3683 adult female 01day    4471 adult female 05day    1234 adult female 30day    875 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034247    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034247 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut, virgin spermatheca, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, adult heart, adult fat body, inseminated spermatheca, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034247 expression level Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut    2738.3 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut  (2738.3) Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca  (708.9) Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland  522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut  (2738.3) Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut    2738.3 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034247 expression level Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut    2738.3 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut  (2738.3) Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca  708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland  522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut  (2738.3) Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    4.325 Larval Midgut    149.3 Larval Hindgut    4.1 Larval Malpighian Tubules    7 Larval Fat Body    5.5 Larval Salivary Gland    3.6 Larval Trachea    3.15 Larval Carcass    3.45 Adult Head    22.2 Adult Eye    5.725 Adult Brain    6.1 Adult Thoracic-Abdominal Ganglion    4.3 Adult Crop    6.7 Adult Midgut    2738.3 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body    317.8 Adult Salivary Gland    4.8 Adult Heart    202.05 Adult VirginFemale Spermatheca    708.9 Adult InseminatedFemale Spermatheca    434.6 Adult Ovary    3.6 Adult Testis    8 Adult Male Accessory Gland    522.6 Adult Carcass    160.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    22.2   NA  Eye    5.725   NA  Brain    6.1   4.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4.3   NA  Crop    6.7   149.3  Midgut    2738.3   4.1  Hindgut    31.8   7  Malpighian Tubules    no informative data   5.5  Fat Body    317.8   3.6  Salivary Gland    4.8   NA  Heart    202.05   3.15  Trachea    NA   NA  VirginFemale Spermatheca    708.9   NA  InseminatedFemale Spermatheca    434.6   NA  Ovary    3.6   NA  Testis    8   NA  Male Accessory Gland    522.6   3.45  Carcass    160.8 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_15
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034247 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6484-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG6484 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG6484GD2054 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG6484 Class Mutagen Stocks Known lesion CG6484e03770 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6484 Class Mutagen Stocks Known lesion CG6484GD2054 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6484KK106784 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7149 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2054} NA P{KK106784} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG6484e03770 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
glucose transmembrane transporter activity inferred from sequence or structural similarity with mouse Slc2a1 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR005828 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6484 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0034247 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36994
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11588 Dere\GG21040 Dgri\GH21817 Dmoj\GI20788 Dper\GL17690 Dpse\GA19628 Dsec\GM19968 Dsim\GD25462 Dvir\GJ20522 Dwil\GK10669 Dyak\GE13983
Curated drosophilid orthologs	Dpse\GA19628   Dsec\CG6484 (Dworkin and Jones, 2009)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • CAL0005849 Candida albicans (a form of yeast) CAGL0I07447g Candida glabrata (haploid yeast) CMK066C Cyanidioschyzon merolae (red alga) KLLA0C12309g Kluyveromyces lactis (yeast) LOC_Os03g24870.1 Oryza sativa (asian rice) 4776442 Sorghum bicolor (sorghum) 4781586 Sorghum bicolor (sorghum) YOL103W Saccharomyces cerevisiae (budding yeast) SPAC20G8.03 Schizosaccharomyces pombe (fission yeast) Tc00.1047053505183.130 Trypanosoma cruzi (parasitic trypanosome) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231618 FBgn0212682 FBgn0208936 FBgn0208935 FBgn0207662 FBgn0196756 FBgn0174854 FBgn0079624 FBgn0155293 FBgn0143523 FBgn0129278 FBgn0113224 FBgn0088628
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v4954 w1118; P{GD2054}v4954
Genomic Clones ( 2 )
	BACR12C23 BACR21A09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 33 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH21490
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE60481
Other clones	CK01399 EK012121 EK051716 RP003033013 RP003068053 RP003077203 RP003077259 RP003091483 RP003091885 RP003181933 RP003196812 RP003239951 RP003279731 RP003280056 RP003304025 RP003318886 RP003321462 RP003342637 RP003344923 RP003425825 RP003433505 RP003444396 RP003444470 RP003509607 RP003576180 RP003611359 RP003613965 RP003625253 RP003626390 RP003640364 RP003666243
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034247 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36994
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137390 RefSeq (Proteins) • NP_611234 DDBJ / EMBL / GenBank • AAF57829 AAL13664 AI390039 AW940827 AY058435 CZ481523 Entrez Gene - A searchable database of RefSeq genes. • 36994 UniProtKB/TrEMBL • Q7K3P6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sugar/inositol transporter (IPR003663) Sugar transporter, conserved site (IPR005829) Major facilitator superfamily domain, general substrate transporter (IPR016196) General substrate transporter (IPR005828) Major facilitator superfamily domain (IPR020846)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0034247 DRSC - Results from RNAi screens. • FBgn0034247 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034247 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6484-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034247 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36994 InParanoid A subset of ortholog calls from InParanoid. • CAL0005849 Candida albicans (a form of yeast) CAGL0I07447g Candida glabrata (haploid yeast) CMK066C Cyanidioschyzon merolae (red alga) KLLA0C12309g Kluyveromyces lactis (yeast) LOC_Os03g24870.1 Oryza sativa (asian rice) 4776442 Sorghum bicolor (sorghum) 4781586 Sorghum bicolor (sorghum) YOL103W Saccharomyces cerevisiae (budding yeast) SPAC20G8.03 Schizosaccharomyces pombe (fission yeast) Tc00.1047053505183.130 Trypanosoma cruzi (parasitic trypanosome) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36994 modMine - Data generated by the modENCODE project. • FBgn0034247 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0231618 FBgn0212682 FBgn0208936 FBgn0208935 FBgn0207662 FBgn0196756 FBgn0174854 FBgn0079624 FBgn0155293 FBgn0143523 FBgn0129278 FBgn0113224 FBgn0088628
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG6484 (Bowler et al., 2006, Jensen et al., 2006, Stergiopoulos et al., 2009, Raja et al., 2010, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 19 )
Research paper	Raja et al., 2010, Mol. Cell 38(6): 827--841 The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila. [FBrf0211222] Dworkin and Jones, 2009, Genetics 181(2): 721--736 Genetic Changes Accompanying the Evolution of Host Specialization in Drosophila sechellia. [FBrf0207106] Stergiopoulos et al., 2009, Physiol. Genomics 37(1): 1--11 Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress. [FBrf0206888] Bowler et al., 2006, Dev. Biol. 299(1): 78--90 Computational identification of Ftz/Ftz-F1 downstream target genes. [FBrf0200137] Jensen et al., 2006, Insect Molec. Biol. 15(3): 329--339 The effect of a synergistic concentration of a Piper nigrum extract used in conjunction with pyrethrum upon gene expression in Drosophila melanogaster. [FBrf0194463] McGraw et al., 2004, Curr. Biol. 14(16): 1509--1514 Genes regulated by mating, sperm, or seminal proteins in mated female Drosophila melanogaster. [FBrf0180059]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126677]