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Gene Dmel\CG10933

General Information
Symbol	Dmel\CG10933	Species	D. melanogaster
Name		Annotation symbol	CG10933
Feature type	protein_coding_gene	FlyBase ID	FBgn0034264
Gene Model Status	Current	Stock availability	10 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	54E2-54E2	Sequence location	2R:13,610,818..13,612,561 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10933 (FBgn0034264). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1638211_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10933. Gene sequence location is 2R:13610818..13612561.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN51364 BKN51287 BKN27019 HFA06016 BKN45457
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 54E2-54E2   Limits computationally determined from genome sequence between P{lacW}l(2)k07509k07509&P{EP}CG10934EP538 and P{EP}subEP616
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10933 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	5prime UTR appears to overlap 3prime UTR of previous gene, CG10934
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10933-RA FBtr0086860  NM_137407   1398   355
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10933-PA   FBpp0086020   40.1   355   4.61     NP_611251   AAF57808
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Src homology-3 domain (IPR001452)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF57808   AY069205   BE975477   BF485714   BF493757   BI369871   BP546821   BP547842   BT001682 AAN71437   BT088857   BT099964   CK657230   CK658281   CO181902   CO267111   CO307733   EC077567   EC233448   GH740928   GH744171   GH747193   GH765354   GH766146   GH768364   GH779641
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IGN9 A1ZAY1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034264    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034264 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034264 expression level Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr  (929) embryo 04-06hr  (3361) embryo 06-08hr  (2772) embryo 08-10hr  (2471) embryo 10-12hr  (2176) embryo 12-14hr  (1386) embryo 14-16hr  (584) embryo 16-18hr  (296) embryo 18-20hr  (214) embryo 20-22hr  (143) embryo 22-24hr  (203) larva L1  (153) larva L2  (274) larva L3 12hr old  (188) larva L3 puffstage 1-2  (593) larva L3 puffstage 3-6  (807) larva L3 puffstage 7-9  (1409) white prepupae new  (1411) white prepupae 12hr  (1814) white prepupae 24hr  (2065) pupae 2d postWPP  (1045) pupae 3d postWPP  (507) pupae 4d postWPP  (188) adult male 01day  (141) adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr  (3361) embryo 06-08hr  (2772) embryo 08-10hr  (2471) embryo 10-12hr  (2176) embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9  1409 white prepupae new  1411 white prepupae 12hr  (1814) white prepupae 24hr  (2065) pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034264 expression level Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr  (929) embryo 04-06hr  (3361) embryo 06-08hr  (2772) embryo 08-10hr  (2471) embryo 10-12hr  (2176) embryo 12-14hr  (1386) embryo 14-16hr  (584) embryo 16-18hr  (296) embryo 18-20hr  (214) embryo 20-22hr  143 embryo 22-24hr  (203) larva L1  (153) larva L2  (274) larva L3 12hr old  (188) larva L3 puffstage 1-2  (593) larva L3 puffstage 3-6  (807) larva L3 puffstage 7-9  (1409) white prepupae new  (1411) white prepupae 12hr  (1814) white prepupae 24hr  (2065) pupae 2d postWPP  (1045) pupae 3d postWPP  (507) pupae 4d postWPP  (188) adult male 01day  141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr  (3361) embryo 06-08hr  (2772) embryo 08-10hr  2471 embryo 10-12hr  2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9  1409 white prepupae new  1411 white prepupae 12hr  1814 white prepupae 24hr  2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    52 embryo 02-04hr    929 embryo 04-06hr    3361 embryo 06-08hr    2772 embryo 08-10hr    2471 embryo 10-12hr    2176 embryo 12-14hr    1386 embryo 14-16hr    584 embryo 16-18hr    296 embryo 18-20hr    214 embryo 20-22hr    143 embryo 22-24hr    203 larva L1    153 larva L2    274 larva L3 12hr old    188 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    807 larva L3 puffstage 7-9    1409 white prepupae new    1411 white prepupae 12hr    1814 white prepupae 24hr    2065 pupae 2d postWPP    1045 pupae 3d postWPP    507 pupae 4d postWPP    188 adult male 01day    141 adult male 05day    73 adult male 30day    80 adult female 01day    100 adult female 05day    22 adult female 30day    28 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034264    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034264 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval trachea. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034264 expression level Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034264 expression level Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.5 Larval Midgut    6.6 Larval Hindgut    65.7 Larval Malpighian Tubules    2.6 Larval Fat Body    9 Larval Salivary Gland    8.1 Larval Trachea    148.375 Larval Carcass    61.6 Adult Head    20.1 Adult Eye    43.25 Adult Brain    2.5 Adult Thoracic-Abdominal Ganglion    3 Adult Crop    67.2 Adult Midgut    4.7 Adult Hindgut    39.7 Adult Malpighian Tubules    6.3 Adult Fat Body    6.3 Adult Salivary Gland    5.8 Adult Heart    1.025 Adult VirginFemale Spermatheca    4.3 Adult InseminatedFemale Spermatheca    8.3 Adult Ovary    1.9 Adult Testis    7.2 Adult Male Accessory Gland    3.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    20.1   NA  Eye    43.25   NA  Brain    2.5   63.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3   NA  Crop    67.2   6.6  Midgut    4.7   65.7  Hindgut    39.7   2.6  Malpighian Tubules    6.3   9  Fat Body    6.3   8.1  Salivary Gland    5.8   NA  Heart    1.025   148.375  Trachea    NA   NA  VirginFemale Spermatheca    4.3   NA  InseminatedFemale Spermatheca    8.3   NA  Ovary    1.9   NA  Testis    7.2   NA  Male Accessory Gland    3.2   61.6  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034264 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10933-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG10933GD7133 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG10933GD7133 semi-lethal | recessive CG1093304 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG10933GD7133 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 CG10933GD7133 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG10933GD7133 trichogen cell, with Scer\GAL4pnr-MD237 CG10933GD7133
Classical Alleles ( 8 )
For All Classical Alleles Show
Allele of CG10933 Class Mutagen Stocks Known lesion CG1093304 1 Yes CG10933c04569a 1 -- CG10933c07171a 1 -- CG10933c07172 1 -- CG10933KG05496 1 -- CG10933c07173 0 -- CG10933Δ1 Delta2-3 0 Yes CG10933Δ2 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10933 Class Mutagen Stocks Known lesion CG10933GD7133 in vitro construct - RNAi in vitro construct - regulatory fusion 4 Yes CG10933KK107019 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7150 (Ryder, 2004.4.26)
Partially disrupted in	Df(2R)Snx16Δ1 (Rodal et al., 2011) Df(2R)Snx16Δ2 (Rodal et al., 2011)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7133} NA P{KK107019} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}CG10933KG05496 NA P{UAST-YFP.Rab26.Q250L}CG1093304 NA PBac{PB}CG10933c04569a NA PBac{PB}CG10933c07171a NA PBac{PB}CG10933c07172 NA PBac{PB}CG10933c07173 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10933 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62700 DroID - A comprehensive database of gene and protein interactions. • FBgn0034264 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37014
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11665 Dere\GG21812 Dgri\GH21638 Dmoj\GI20091 Dper\GL16792 Dpse\GA24296 Dsec\GM21814 Dsim\GD11305 Dvir\GJ19858 Dwil\GK23256 Dyak\GE11889
Curated drosophilid orthologs	Dpse\GA10652
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001262-PA Aedes aegypti (mosquito) AGAP005616-PA Anopheles gambiae (mosquito) XP_623845.2 Apis mellifera (honey bee) XP_001950019.1 Acyrthosiphon pisum (pea aphid) 218678 Branchiostoma floridae (lancelet) BGIBMGA012878-PA Bombyx mori (silk worm) CN01658 Caenorhabditis brenneri (small nematode) CBP26179 Caenorhabditis briggsae (nematode) CE39135 Caenorhabditis elegans (worm) JA02045 Caenorhabditis japonica (nematode) CPIJ002311 Culex pipens (mosquito) RP44387 Caenorhabditis remanei (nematode) 313770 Daphnia pulex (daphnia) 130482 Lottia gigantea (owl limpet) 221077 Nematostella vectensis (starlet anemone) XP_001603810.1 Nasonia vitripennis (wasp) ENSPTRP00000015127 Pan troglodytes (chimpanzee) 56417 Trichoplax adhaerens (metazoa) XP_970913.2 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB19266 NV14329 LH15005 FBgn0229673 FBgn0225218 FBgn0207000 FBgn0183054 FBgn0176691 JGI_V11_313770 FBgn0245693 FBgn0154396 FBgn0142827 FBgn0129099 FBgn0120416 FBgn0113990 FBgn0088705 CPIJ002311 BGIBMGA012878 ACYPI002938 GB14161 AGAP005616 AAEL014832 AAEL001262 PHUM601210 GLEAN_14503
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	14207 y1 w67c23; P{SUPor-P}CG10933KG05496 9809 y1 w*; P{UAST-YFP.Rab26.Q250L}CG1093304/CyO
Harvard	- PBac{PB}CG10933c07172 - PBac{PB}CG10933c07171a, PBac{PB}c07171b - PBac{PB}CG10933c04569a, PBac{PB}Ctr1Ac04569b
VDRC	v104282 P{KK107019}VIE-260B v16103 w1118 P{GD7133}v16103 v46726 w1118; P{GD7133}v46726 v46724 w1118; P{GD7133}v46724/TM3 v46727 w1118; P{GD7133}v46727/TM3
Genomic Clones ( 1 )
	BACR12C23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 22 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH26058 RE56202
Other clones	DPiM_GH26058 FI04490 FI04491
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02094 AT19665 LP15108 LP23357
Other clones	bs43e02 EC15454 EK148742 EK255436 FGH110E01 FGH121C07 RP001022252 RP001030714 RP001034897 RP001047453 RP001051668 RP001053583 RP001055382
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034264 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37014
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137407 RefSeq (Proteins) • NP_611251 DDBJ / EMBL / GenBank • AAF57808 AAN71437 BI369871 BT001682 Entrez Gene - A searchable database of RefSeq genes. • 37014 UniProtKB/TrEMBL • A1ZAY1 Q8IGN9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Src homology-3 domain (IPR001452)
Linkouts
	BioGRID - A database of protein and genetic interactions • 62700 DroID - A comprehensive database of gene and protein interactions. • FBgn0034264 DRSC - Results from RNAi screens. • FBgn0034264 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034264 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10933-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034264 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37014 InParanoid A subset of ortholog calls from InParanoid. • AAEL001262-PA Aedes aegypti (mosquito) AGAP005616-PA Anopheles gambiae (mosquito) XP_623845.2 Apis mellifera (honey bee) XP_001950019.1 Acyrthosiphon pisum (pea aphid) 218678 Branchiostoma floridae (lancelet) BGIBMGA012878-PA Bombyx mori (silk worm) CN01658 Caenorhabditis brenneri (small nematode) CBP26179 Caenorhabditis briggsae (nematode) CE39135 Caenorhabditis elegans (worm) JA02045 Caenorhabditis japonica (nematode) CPIJ002311 Culex pipens (mosquito) RP44387 Caenorhabditis remanei (nematode) 313770 Daphnia pulex (daphnia) 130482 Lottia gigantea (owl limpet) 221077 Nematostella vectensis (starlet anemone) XP_001603810.1 Nasonia vitripennis (wasp) ENSPTRP00000015127 Pan troglodytes (chimpanzee) 56417 Trichoplax adhaerens (metazoa) XP_970913.2 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37014 modMine - Data generated by the modENCODE project. • FBgn0034264 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB19266 NV14329 LH15005 FBgn0229673 FBgn0225218 FBgn0207000 FBgn0183054 FBgn0176691 JGI_V11_313770 FBgn0245693 FBgn0154396 FBgn0142827 FBgn0129099 FBgn0120416 FBgn0113990 FBgn0088705 CPIJ002311 BGIBMGA012878 ACYPI002938 GB14161 AGAP005616 AAEL014832 AAEL001262 PHUM601210 GLEAN_14503
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10933 (Zhang et al., 2007, Keleman et al., 2009.8.5, Rodal et al., 2011)
Name Synonym
Secondary FlyBase IDs
References ( 16 )
Research paper	Rodal et al., 2011, J. Cell Biol. 193(1): 201--217 A presynaptic endosomal trafficking pathway controls synaptic growth signaling. [FBrf0213353] Gonzalez-Aguero et al., 2005, Gene 345(2): 213--224 Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization. [FBrf0187577]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Zhang et al., 2007, Genetics 176(2): Supplement to Zhang et al., 2007. [FBrf0203184] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]