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Gene Dmel\CG10914

General Information
Symbol	Dmel\CG10914	Species	D. melanogaster
Name		Annotation symbol	CG10914
Feature type	protein_coding_gene	FlyBase ID	FBgn0034307
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	55B9-55B9	Sequence location	2R:14,045,772..14,047,815 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10914 (FBgn0034307). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GTP-binding domain, HSR1-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1627851_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10914. Gene sequence location is 2R:14045772..14047815.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN27610 HFA06010
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 55B9-55B9   Limits computationally determined from genome sequence between P{PZ}Hsf03091&P{EP}Dgp-1EP731 and P{PZ}sbb04525&P{EP}EP1081EP1081
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10914 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10914-RA FBtr0086745  NM_137453   2044   624
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10914-PA   FBpp0085924   70.6   624   9.44     NP_611297   AAF57738
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GTP-binding domain, HSR1-related (IPR002917)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA735989   AA736015   AE013599 AAF57738   AY071190 AAL48812   BI216514   CZ470409   GH740265   GH742098   GH744851   GH745435   GH746524   GH764769   GH765040   GH766002   GH766491   GH766889   GH768024   GH779388   GH779408   GH779648   GH779690
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SZ15
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034307    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034307 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034307 expression level Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (597) embryo 02-04hr  (665) embryo 04-06hr  (923) embryo 06-08hr  (793) embryo 08-10hr  (537) embryo 10-12hr  (461) embryo 12-14hr  (424) embryo 14-16hr  (531) embryo 16-18hr  (612) embryo 18-20hr  (366) embryo 20-22hr  (247) embryo 22-24hr  (180) larva L1  (552) larva L2  (600) larva L3 12hr old  (359) larva L3 puffstage 1-2  (171) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  (261) white prepupae new  (243) white prepupae 12hr  (315) white prepupae 24hr  (376) pupae 2d postWPP  (438) pupae 3d postWPP  (428) pupae 4d postWPP  (202) adult male 01day  (219) adult male 05day  (260) adult male 30day  (249) adult female 01day  (494) adult female 05day  (713) adult female 30day  (684) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034307 expression level Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (597) embryo 02-04hr  (665) embryo 04-06hr  (923) embryo 06-08hr  (793) embryo 08-10hr  (537) embryo 10-12hr  (461) embryo 12-14hr  (424) embryo 14-16hr  (531) embryo 16-18hr  (612) embryo 18-20hr  (366) embryo 20-22hr  (247) embryo 22-24hr  (180) larva L1  (552) larva L2  (600) larva L3 12hr old  (359) larva L3 puffstage 1-2  (171) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  (261) white prepupae new  (243) white prepupae 12hr  (315) white prepupae 24hr  (376) pupae 2d postWPP  (438) pupae 3d postWPP  (428) pupae 4d postWPP  (202) adult male 01day  (219) adult male 05day  (260) adult male 30day  (249) adult female 01day  (494) adult female 05day  (713) adult female 30day  (684) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    597 embryo 02-04hr    665 embryo 04-06hr    923 embryo 06-08hr    793 embryo 08-10hr    537 embryo 10-12hr    461 embryo 12-14hr    424 embryo 14-16hr    531 embryo 16-18hr    612 embryo 18-20hr    366 embryo 20-22hr    247 embryo 22-24hr    180 larva L1    552 larva L2    600 larva L3 12hr old    359 larva L3 puffstage 1-2    171 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    261 white prepupae new    243 white prepupae 12hr    315 white prepupae 24hr    376 pupae 2d postWPP    438 pupae 3d postWPP    428 pupae 4d postWPP    202 adult male 01day    219 adult male 05day    260 adult male 30day    249 adult female 01day    494 adult female 05day    713 adult female 30day    684 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034307    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034307 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034307 expression level Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034307 expression level Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.825 Larval Midgut    31.7 Larval Hindgut    52.1 Larval Malpighian Tubules    23.3 Larval Fat Body no informative data Larval Salivary Gland    26.7 Larval Trachea    32.4 Larval Carcass    44.325 Adult Head    26.8 Adult Eye    24.275 Adult Brain    36.8 Adult Thoracic-Abdominal Ganglion    43.7 Adult Crop    24.3 Adult Midgut no informative data Adult Hindgut    30.8 Adult Malpighian Tubules    46.9 Adult Fat Body    61.9 Adult Salivary Gland no informative data Adult Heart    34.425 Adult VirginFemale Spermatheca    54.6 Adult InseminatedFemale Spermatheca    52 Adult Ovary    92.7 Adult Testis    31.2 Adult Male Accessory Gland    32.1 Adult Carcass    30.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    26.8   NA  Eye    24.275   NA  Brain    36.8   71.825  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    43.7   NA  Crop    24.3   31.7  Midgut    no informative data   52.1  Hindgut    30.8   23.3  Malpighian Tubules    46.9   no informative data  Fat Body    61.9   26.7  Salivary Gland    no informative data   NA  Heart    34.425   32.4  Trachea    NA   NA  VirginFemale Spermatheca    54.6   NA  InseminatedFemale Spermatheca    52   NA  Ovary    92.7   NA  Testis    31.2   NA  Male Accessory Gland    32.1   44.325  Carcass    30.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034307 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10914-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG10914GD7123 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG10914 Class Mutagen Stocks Known lesion CG10914c05992 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10914 Class Mutagen Stocks Known lesion CG10914GD7123 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10914KK107610 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7152 (Ryder, 2004.4.26) Df(2R)Exel7153 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7123} NA P{KK107610} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG10914c05992 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10914 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62757 DroID - A comprehensive database of gene and protein interactions. • FBgn0034307 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37075
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12654 Dere\GG21848 Dgri\GH21055 Dmoj\GI18656 Dper\GL11551 Dpse\GA10638 Dsec\GM21850 Dsim\GD11344 Dvir\GJ21673 Dwil\GK19491 Dyak\GE11927
Curated drosophilid orthologs	Dpse\GA10638
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008086-PA Aedes aegypti (mosquito) AAEL008095-PA Aedes aegypti (mosquito) AGAP010271-PA Anopheles gambiae (mosquito) XP_396974.3 Apis mellifera (honey bee) XP_001952820.1 Acyrthosiphon pisum (pea aphid) At3g47450.1 Arabidopsis thaliana (wall cress) 85971 Batrachochytrium dendrobatidis (chytrid fungus) 115313 Branchiostoma floridae (lancelet) XP_001893531.1 Brugia malayi (roundworm nematode) BGIBMGA007976-PA Bombyx mori (silk worm) ENSBTAP00000025792 Bos taurus (bovine) CN26048 Caenorhabditis brenneri (small nematode) CBP30102 Caenorhabditis briggsae (nematode) CE28989 Caenorhabditis elegans (worm) ENSCAFP00000003278 Canis familiaris (dog) JA03843 Caenorhabditis japonica (nematode) CME141C Cyanidioschyzon merolae (red alga) CPIJ002584 Culex pipens (mosquito) ENSCPOP00000018683 Cavia porcellus (guinea pig) 174922 Chlamidomonas reinhardtii (green alga) RP30891 Caenorhabditis remanei (nematode) 19738 Capitella spl (polychaete worm) DDB0204555 Dictyostelium discoideum (amoeba) 313052 Daphnia pulex (daphnia) ENSECAP00000018108 Equus caballus (horse) ENSGACP00000021534 Gymnopilus aculeatus (mushroom) ENSGALP00000031537 Gallus gallus (chicken) ENSP00000264230 Homo sapiens (human) KLLA0F01144g Kluyveromyces lactis (yeast) 124576 Lottia gigantea (owl limpet) LmjF30.0840 Leishmania major (virus) ENSMODP00000025897 Monodelphis domestica (gray opossum) ENSMMUP00000029659 Macaca mulatta (rhesus monkey) ENSMUSP00000045948 Mus musculus (house mouse) 21779 Nematostella vectensis (starlet anemone) XP_001599126.1 Nasonia vitripennis (wasp) ENSOANP00000029100 Ornithorynchus anatinus (platypus) ENSORLP00000025389 Oryzias latipes (japanese killifish) LOC_Os02g01440.1 Oryza sativa (asian rice) 17927 Ostreococcus tauri (green alga) PF14_0564 Plasmodium falciparum (protozoal parasite) PHUM004680-PA Pediculus humanus (human body louse) 21847 Physcomitrella patens (moss) ENSPPYP00000016469 Pongo pygmaeus (orangutan) 84860 Phytophthora ramorum (sudden oak death pathogen) 178021 Populus trichocarpa (black cottonwood) ENSPTRP00000027668 Pan troglodytes (chimpanzee) PVX_117505 Plasmodium vivax (protozoal parasite) ENSRNOP00000002810 Rattus norvegicus (norway rat) 144093 Sorghum bicolor (sorghum) Smp_134940 Schistosoma mansoni (trematode parasite) 60700 Trichoplax adhaerens (metazoa) TA19855 Theileria annulata (apicomplexan parasite) XP_971651.1 Tribolium castaneum (red flour beetle) Tc00.1047053509965.400 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009118 Tetraodon nigroviridis (green spotted pufferfish) TP02_0603 Theileria parva (parasitic protozoan) ENSTRUP00000045325 Takifugu rubripes (pufferfish Takifugu) 3692.m00114 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000056181 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12328 NV16577 LH16846 ISCW014370 ISCW014371 FBgn0229709 FBgn0221489 FBgn0208792 FBgn0183093 FBgn0176727 JGI_V11_313052 FBgn0070694 FBgn0149160 FBgn0141395 FBgn0128517 FBgn0114026 FBgn0089690 CPIJ002584 BGIBMGA007976 ACYPI003097 GB19759 AGAP010271 AAEL008095 AAEL008086 PHUM513370 GLEAN_12448
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v108735 P{KK107610}VIE-260B v38420 w1118 P{GD7123}v38420 v38419 w1118; P{GD7123}v38419
Genomic Clones ( 2 )
	BACR15G20 BACR33K09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 18 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE23670
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM10253 GM10286
Other clones	RP001002361 RP001004277 RP001007109 RP001008789 RP001009551 RP001011328 RP001012737 RP001013566 RP001015401 RP001016081 RP001017996 RP001018301 RP001034660 RP001042392 RP001052121
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034307 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37075
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137453 RefSeq (Proteins) • NP_611297 DDBJ / EMBL / GenBank • AAF57738 AAL48812 AY071190 BI216514 CZ470409 Entrez Gene - A searchable database of RefSeq genes. • 37075 UniProtKB/TrEMBL • Q8SZ15
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GTP-binding domain, HSR1-related (IPR002917)
Linkouts
	BioGRID - A database of protein and genetic interactions • 62757 DroID - A comprehensive database of gene and protein interactions. • FBgn0034307 DRSC - Results from RNAi screens. • FBgn0034307 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034307 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10914-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034307 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37075 InParanoid A subset of ortholog calls from InParanoid. • AAEL008086-PA Aedes aegypti (mosquito) AAEL008095-PA Aedes aegypti (mosquito) AGAP010271-PA Anopheles gambiae (mosquito) XP_396974.3 Apis mellifera (honey bee) XP_001952820.1 Acyrthosiphon pisum (pea aphid) At3g47450.1 Arabidopsis thaliana (wall cress) 85971 Batrachochytrium dendrobatidis (chytrid fungus) 115313 Branchiostoma floridae (lancelet) XP_001893531.1 Brugia malayi (roundworm nematode) BGIBMGA007976-PA Bombyx mori (silk worm) ENSBTAP00000025792 Bos taurus (bovine) CN26048 Caenorhabditis brenneri (small nematode) CBP30102 Caenorhabditis briggsae (nematode) CE28989 Caenorhabditis elegans (worm) ENSCAFP00000003278 Canis familiaris (dog) JA03843 Caenorhabditis japonica (nematode) CME141C Cyanidioschyzon merolae (red alga) CPIJ002584 Culex pipens (mosquito) ENSCPOP00000018683 Cavia porcellus (guinea pig) 174922 Chlamidomonas reinhardtii (green alga) RP30891 Caenorhabditis remanei (nematode) 19738 Capitella spl (polychaete worm) DDB0204555 Dictyostelium discoideum (amoeba) 313052 Daphnia pulex (daphnia) ENSECAP00000018108 Equus caballus (horse) ENSGACP00000021534 Gymnopilus aculeatus (mushroom) ENSGALP00000031537 Gallus gallus (chicken) ENSP00000264230 Homo sapiens (human) KLLA0F01144g Kluyveromyces lactis (yeast) 124576 Lottia gigantea (owl limpet) LmjF30.0840 Leishmania major (virus) ENSMODP00000025897 Monodelphis domestica (gray opossum) ENSMMUP00000029659 Macaca mulatta (rhesus monkey) ENSMUSP00000045948 Mus musculus (house mouse) 21779 Nematostella vectensis (starlet anemone) XP_001599126.1 Nasonia vitripennis (wasp) ENSOANP00000029100 Ornithorynchus anatinus (platypus) ENSORLP00000025389 Oryzias latipes (japanese killifish) LOC_Os02g01440.1 Oryza sativa (asian rice) 17927 Ostreococcus tauri (green alga) PF14_0564 Plasmodium falciparum (protozoal parasite) PHUM004680-PA Pediculus humanus (human body louse) 21847 Physcomitrella patens (moss) ENSPPYP00000016469 Pongo pygmaeus (orangutan) 84860 Phytophthora ramorum (sudden oak death pathogen) 178021 Populus trichocarpa (black cottonwood) ENSPTRP00000027668 Pan troglodytes (chimpanzee) PVX_117505 Plasmodium vivax (protozoal parasite) ENSRNOP00000002810 Rattus norvegicus (norway rat) 144093 Sorghum bicolor (sorghum) Smp_134940 Schistosoma mansoni (trematode parasite) 60700 Trichoplax adhaerens (metazoa) TA19855 Theileria annulata (apicomplexan parasite) XP_971651.1 Tribolium castaneum (red flour beetle) Tc00.1047053509965.400 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009118 Tetraodon nigroviridis (green spotted pufferfish) TP02_0603 Theileria parva (parasitic protozoan) ENSTRUP00000045325 Takifugu rubripes (pufferfish Takifugu) 3692.m00114 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000056181 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37075 modMine - Data generated by the modENCODE project. • FBgn0034307 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12328 NV16577 LH16846 ISCW014370 ISCW014371 FBgn0229709 FBgn0221489 FBgn0208792 FBgn0183093 FBgn0176727 JGI_V11_313052 FBgn0070694 FBgn0149160 FBgn0141395 FBgn0128517 FBgn0114026 FBgn0089690 CPIJ002584 BGIBMGA007976 ACYPI003097 GB19759 AGAP010271 AAEL008095 AAEL008086 PHUM513370 GLEAN_12448
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10914 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]