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Gene Dmel\CG5335

General Information
Symbol	Dmel\CG5335	Species	D. melanogaster
Name		Annotation symbol	CG5335
Feature type	protein_coding_gene	FlyBase ID	FBgn0034365
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	55E2-55E2	Sequence location	2R:14,509,050..14,510,475 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5335 (FBgn0034365). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: sugar binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup; Galectin, carbohydrate recognition domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult heart, adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631627_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5335. Gene sequence location is 2R:14509050..14510475.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA06931 BKN25516
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 55E2-55E2   Limits computationally determined from genome sequence between P{EP}EP437 and P{PZ}l(2)0370903709
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5335 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5335-RA FBtr0086708  NM_137505   1253   321
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5335-PA   FBpp0085887   36.7   321   6.58     NP_611349   AAF57667
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Galectin, carbohydrate recognition domain (IPR001079) Concanavalin A-like lectin/glucanase (IPR008985) Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695866   AE013599 AAF57667   AW941227   AY060892 AAL28440   BF500594   BI173149   BI636012   BP548613   BT003230   BT050574   CK135972   CO181492   CO270325   CO304483   CO313901   EC076681   EC088171   EC243191   EV584665   GH747726   GH752183   GH753071   GH754333   GH754582   GH757138   GH782897   GH789353   GH793693   GH794199   GH794952   GH798666   GH801165   GH807807   GH809341   GH811200   GH812315   GH815597   GH819690   GH821765   GH827300   GH831276   GH832734   GH832846   GH833113   GH838379   GH838676   GH839284   GH839326   GH840035   GH845944   GH852585   GH858646   GH867506   GH875412   GH882223   GH887842   GH890880   GH892564   GH892868   GH901856   GH901964   GH907353   GH914817   GH916422   GH922781   GH925650   GH929714   GH934529   GH940935   GH942295   GH942561
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95SA3 A1ZBB1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034365    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034365 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034365 expression level Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (933) embryo 02-04hr  (375) embryo 04-06hr    94 embryo 06-08hr  (154) embryo 08-10hr  (299) embryo 10-12hr  (2000) embryo 12-14hr  (1752) embryo 14-16hr  (1420) embryo 16-18hr  (1191) embryo 18-20hr  (1345) embryo 20-22hr  (2413) embryo 22-24hr  (2698) larva L1  (1848) larva L2  (1813) larva L3 12hr old  (1796) larva L3 puffstage 1-2  (3091) larva L3 puffstage 3-6  (2503) larva L3 puffstage 7-9  (2571) white prepupae new  (1587) white prepupae 12hr  (702) white prepupae 24hr  (484) pupae 2d postWPP  (414) pupae 3d postWPP  (348) pupae 4d postWPP  (613) adult male 01day  (1211) adult male 05day  (1302) adult male 30day  (1259) adult female 01day  (1466) adult female 05day  (1550) adult female 30day  (1700) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr  (2000) embryo 12-14hr  (1752) embryo 14-16hr  1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr  (2413) embryo 22-24hr  (2698) larva L1  (1848) larva L2  (1813) larva L3 12hr old  (1796) larva L3 puffstage 1-2  (3091) larva L3 puffstage 3-6  (2503) larva L3 puffstage 7-9  (2571) white prepupae new  (1587) white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day  1466 adult female 05day  (1550) adult female 30day  (1700) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034365 expression level Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (933) embryo 02-04hr  (375) embryo 04-06hr    94 embryo 06-08hr  (154) embryo 08-10hr  (299) embryo 10-12hr  (2000) embryo 12-14hr  (1752) embryo 14-16hr  (1420) embryo 16-18hr  (1191) embryo 18-20hr  (1345) embryo 20-22hr  (2413) embryo 22-24hr  (2698) larva L1  (1848) larva L2  (1813) larva L3 12hr old  (1796) larva L3 puffstage 1-2  (3091) larva L3 puffstage 3-6  (2503) larva L3 puffstage 7-9  (2571) white prepupae new  (1587) white prepupae 12hr  (702) white prepupae 24hr  (484) pupae 2d postWPP  (414) pupae 3d postWPP  (348) pupae 4d postWPP  (613) adult male 01day  (1211) adult male 05day  (1302) adult male 30day  (1259) adult female 01day  (1466) adult female 05day  (1550) adult female 30day  (1700) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr  2000 embryo 12-14hr  1752 embryo 14-16hr  1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr  2413 embryo 22-24hr  (2698) larva L1  1848 larva L2  1813 larva L3 12hr old  1796 larva L3 puffstage 1-2  (3091) larva L3 puffstage 3-6  (2503) larva L3 puffstage 7-9  (2571) white prepupae new  1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day  1466 adult female 05day  1550 adult female 30day  1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    933 embryo 02-04hr    375 embryo 04-06hr    94 embryo 06-08hr    154 embryo 08-10hr    299 embryo 10-12hr    2000 embryo 12-14hr    1752 embryo 14-16hr    1420 embryo 16-18hr    1191 embryo 18-20hr    1345 embryo 20-22hr    2413 embryo 22-24hr    2698 larva L1    1848 larva L2    1813 larva L3 12hr old    1796 larva L3 puffstage 1-2    3091 larva L3 puffstage 3-6    2503 larva L3 puffstage 7-9    2571 white prepupae new    1587 white prepupae 12hr    702 white prepupae 24hr    484 pupae 2d postWPP    414 pupae 3d postWPP    348 pupae 4d postWPP    613 adult male 01day    1211 adult male 05day    1302 adult male 30day    1259 adult female 01day    1466 adult female 05day    1550 adult female 30day    1700 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034365    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034365 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult heart, adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034365 expression level Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut    1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut    1099.5 Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut  (1016.1) Larval Hindgut  (909.9) Larval Malpighian Tubules  534 Larval Fat Body    85.8 Larval Salivary Gland  (775) Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut  (1099.5) Adult Hindgut  (638.7) Adult Malpighian Tubules  (868.5) Adult Fat Body    189.5 Adult Salivary Gland  (840.3) Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut  1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut  (1099.5) Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut    1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut    1099.5 Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034365 expression level Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut    1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut    1099.5 Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut  (1016.1) Larval Hindgut  (909.9) Larval Malpighian Tubules  534 Larval Fat Body    85.8 Larval Salivary Gland  775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut  (1099.5) Adult Hindgut  638.7 Adult Malpighian Tubules  (868.5) Adult Fat Body    189.5 Adult Salivary Gland  (840.3) Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut  1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut  1099.5 Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    16.475 Larval Midgut    1016.1 Larval Hindgut    909.9 Larval Malpighian Tubules    534 Larval Fat Body    85.8 Larval Salivary Gland    775 Larval Trachea    172.275 Larval Carcass    93.325 Adult Head    141.6 Adult Eye    148.125 Adult Brain    54.8 Adult Thoracic-Abdominal Ganglion    61.7 Adult Crop    479.3 Adult Midgut    1099.5 Adult Hindgut    638.7 Adult Malpighian Tubules    868.5 Adult Fat Body    189.5 Adult Salivary Gland    840.3 Adult Heart    257.65 Adult VirginFemale Spermatheca    299.8 Adult InseminatedFemale Spermatheca    264.6 Adult Ovary    211.9 Adult Testis    25.5 Adult Male Accessory Gland    491.7 Adult Carcass    122.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    141.6   NA  Eye    148.125   NA  Brain    54.8   16.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    61.7   NA  Crop    479.3   1016.1  Midgut    1099.5   909.9  Hindgut    638.7   534  Malpighian Tubules    868.5   85.8  Fat Body    189.5   775  Salivary Gland    840.3   NA  Heart    257.65   172.275  Trachea    NA   NA  VirginFemale Spermatheca    299.8   NA  InseminatedFemale Spermatheca    264.6   NA  Ovary    211.9   NA  Testis    25.5   NA  Male Accessory Gland    491.7   93.325  Carcass    122.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_20
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034365 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5335-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG5335d30 viable, with Scer\GAL4pnr-MD237 CG5335GD11611 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5335 Class Mutagen Stocks Known lesion CG5335d30 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5335 Class Mutagen Stocks Known lesion CG5335GD11611 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5335KK104556 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Atg7d77 (Juhász et al., 2007) Df(2R)Exel7157 (Ryder, 2004.4.26)
Partially disrupted in	Df(2R)CG5335d30 (Juhász et al., 2007)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11611} NA P{KK104556} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}Atg7d05866 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
sugar binding inferred from electronic annotation with InterPro:IPR001079 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5335 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0034365
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11976 Dere\GG21911 Dgri\GH20302 Dmoj\GI19972 Dper\GL17029 Dpse\GA18810 Dsec\GM21902 Dsim\GD11398 Dvir\GJ21223 Dwil\GK21966 Dyak\GE11985
Curated drosophilid orthologs	Dpse\GA18810
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012135-PA Aedes aegypti (mosquito) AGAP000341-PA Anopheles gambiae (mosquito) XP_001900812.1 Brugia malayi (roundworm nematode) CN12654 Caenorhabditis brenneri (small nematode) CBP08203 Caenorhabditis briggsae (nematode) CE16577 Caenorhabditis elegans (worm) JA13126 Caenorhabditis japonica (nematode) CPIJ000665 Culex pipens (mosquito) RP38584 Caenorhabditis remanei (nematode) ISCW020586-PA Ixodes scapularis (deer tick) XP_001602230.1 Nasonia vitripennis (wasp) PP00320 Pristionchus pacificus (nematode) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229763 FBgn0223951 FBgn0208356 FBgn0183147 FBgn0176779 JGI_V11_103164 JGI_V11_303864 JGI_V11_224569 FBgn0245733 FBgn0078810 FBgn0154633 FBgn0142709 FBgn0127766 FBgn0114089 FBgn0089015 CPIJ000665 GALE2
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v101295 P{KK104556}VIE-260B v22068 w1118; P{GD11611}v22068/TM3
Genomic Clones ( 1 )
	BACR27L09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 66 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM04669 LP07910
Other clones	FI06810
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT15580 RE15902
Other clones	107864 CK01.127D.A2 Dmel_dig_013816_0635_2374 EC14416 EK098525 EK234252 EK244761 FGH129F08 RP003032008 RP003048127 RP003058994 RP003106350 RP003113125 RP003115938 RP003119424 RP003136329 RP003156707 RP003161858 RP003166788 RP003194083 RP003199638 RP003222461 RP003226377 RP003229199 RP003242261 RP003245795 RP003266256 RP003316461 RP003326760 RP003327024 RP003332775 RP003372766 RP003375284 RP003406660 RP003415450 RP003447510 RP003447703 RP003467939 RP003470930 RP003489712 RP003495254 RP003497887 RP003503439 RP003516167 RP003524871 RP003529682 RP003537520 RP003545098 RP003557154 RP003564437 RP003574026 RP003598984 RP003604183 RP003604900 RP003605022 RP003617791 RP003640916 RP003642665 RP003652082 RP003655440 SD17570
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034365 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37140
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137505 RefSeq (Proteins) • NP_611349 DDBJ / EMBL / GenBank • AA695866 AAF57667 AAL28440 AW941227 AY060892 BI636012 Entrez Gene - A searchable database of RefSeq genes. • 37140 UniProtKB/TrEMBL • A1ZBB1 Q95SA3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Galectin, carbohydrate recognition domain (IPR001079) Concanavalin A-like lectin/glucanase (IPR008985) Concanavalin A-like lectin/glucanase, subgroup (IPR013320)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0034365 DRSC - Results from RNAi screens. • FBgn0034365 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034365 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5335-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034365 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37140 InParanoid A subset of ortholog calls from InParanoid. • AAEL012135-PA Aedes aegypti (mosquito) AGAP000341-PA Anopheles gambiae (mosquito) XP_001900812.1 Brugia malayi (roundworm nematode) CN12654 Caenorhabditis brenneri (small nematode) CBP08203 Caenorhabditis briggsae (nematode) CE16577 Caenorhabditis elegans (worm) JA13126 Caenorhabditis japonica (nematode) CPIJ000665 Culex pipens (mosquito) RP38584 Caenorhabditis remanei (nematode) ISCW020586-PA Ixodes scapularis (deer tick) XP_001602230.1 Nasonia vitripennis (wasp) PP00320 Pristionchus pacificus (nematode) modMine - Data generated by the modENCODE project. • FBgn0034365 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229763 FBgn0223951 FBgn0208356 FBgn0183147 FBgn0176779 JGI_V11_103164 JGI_V11_303864 JGI_V11_224569 FBgn0245733 FBgn0078810 FBgn0154633 FBgn0142709 FBgn0127766 FBgn0114089 FBgn0089015 CPIJ000665 GALE2
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5335 (Juhász et al., 2007, Hou et al., 2008, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Hou et al., 2008, J. Cell Biol. 182(6): 1127--1139 Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis. [FBrf0206034] Juhász et al., 2007, Genes Dev. 21(23): 3061--3066 Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. [FBrf0201603]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Review	Cooper, 2002, Biochim. biophys. Acta 1572(2-3): 209--231 Galectinomics: finding themes in complexity. [FBrf0155571]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Milshina, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126686]