FlyBase Gene Report: Dmel\Hsl

General Information

Symbol

Dmel\Hsl

Species

D. melanogaster

Name

Hormone-sensitive lipase

Annotation Symbol

CG11055

Feature Type

protein_coding_gene

FlyBase ID

FBgn0034491

Gene Model Status

Current

Stock Availability

6 publicly available

Enzyme Name (EC)

sterol esterase (3.1.1.13)

acylglycerol lipase (3.1.1.23)

triacylglycerol lipase (3.1.1.3)

Gene Summary

Hormone-sensitive lipase (Hsl) encodes a protein involved in lipid storage. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

dHSL, DmHSL

Key Links

Genomic Location

Cytogenetic map

56F11-56F11

Sequence location

2R:20,257,650..20,261,726 [+]

Recombination map

2-90

RefSeq locus

NT_033778 REGION:20257650..20261726

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (5 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

enables hydrolase activity

inferred from electronic annotation with InterPro:IPR013094

(InterPro Project Members, 2004-)

enables lipase activity

inferred from electronic annotation with InterPro:IPR010468

(InterPro Project Members, 2004-)

enables monoacylglycerol lipase activity

inferred from sequence or structural similarity with UniProtKB:P54310

(Gene Ontology Curators, 2002-)

enables sterol ester esterase activity

inferred from biological aspect of ancestor with PANTHER:PTN002745229

(GO Reference Genome Project, 2011-)

enables triacylglycerol lipase activity

inferred from sequence or structural similarity with UniProtKB:Q05469

(Gene Ontology Curators, 2002-)

inferred from biological aspect of ancestor with PANTHER:PTN002745229

(GO Reference Genome Project, 2011-)

Biological Process (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in triglyceride mobilization

inferred from mutant phenotype

(Bi et al., 2012)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in cholesterol metabolic process

inferred from electronic annotation with InterPro:IPR010468

(InterPro Project Members, 2004-)

involved_in lipid catabolic process

inferred from electronic annotation with InterPro:IPR010468

(InterPro Project Members, 2004-)

involved_in triglyceride catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN002745229

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in cytosol

inferred from direct assay

(Bi et al., 2012)

is_active_in lipid droplet

inferred from direct assay

(Ueda et al., 2022, Bi et al., 2012)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytosol

inferred from biological aspect of ancestor with PANTHER:PTN002745229

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

ACYLGLYCEROL LIPASES

UNCLASSIFIED TRIGLYCERIDE LIPASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

sterol ester esterase activity

a sterol ester + H2O = a sterol + a fatty acid + H(+) (3.1.1.13)

RHEA 10100: triacylglycerol lipase activity

a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+) (3.1.1.3)

RHEA 12044: monoacylglycerol lipase activity

Hydrolyzes glycerol monoesters of long-chain fatty acids (3.1.1.23)

RHEA 15245:

Summaries

Gene Snapshot

Hormone-sensitive lipase (Hsl) encodes a protein involved in lipid storage. [Date last reviewed: 2019-03-07]

Gene Group (FlyBase)

ACYLGLYCEROL LIPASES -: Acylglycerol lipases are hydrolases that catalyze the conversion of acylglycerol into a fatty acid and glycerol.
UNCLASSIFIED TRIGLYCERIDE LIPASES -: This group comprises triglyceride lipases that do not classify under other groups in FlyBase.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Hsl for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q7JR83)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.51

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Hsl-RA

FBtr0086271

NM_166381

3554

881

Hsl-RB

FBtr0086270

NM_137619

3522

881

Hsl-RC

FBtr0086272

NM_166382

3613

881

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Hsl-PA

FBpp0085583

97.5

881

4.97

FBpp0085582

97.5

881

4.97

FBpp0085584

97.5

881

4.97

Q7JR83

NP_725942

AAM68400

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

881 aa isoforms: Hsl-PA, Hsl-PB, Hsl-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Hsl using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Hsl_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.14

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 5

organism | ubiquitous

(Bi et al., 2012)

embryonic stage 14

embryonic/larval gut

(Bi et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

organism

(Bi et al., 2012)

Additional Descriptive Data

Hsl transcripts are detected through development but are very abundant in early embryos. They are ubiquitously distributed in blastoderm embryos and are found in the digestive tract in mid-stage embryos. RT-PCR shows that is also widely expressed in various tissues in third instar larvae.

(Bi et al., 2012)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytosol

inferred from direct assay

(Bi et al., 2012)

is_active_in lipid droplet

inferred from direct assay

(Ueda et al., 2022, Bi et al., 2012)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Hsl in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Hsl

View exonic expression by tissue for Dmel\Hsl

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37289/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034491

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034491

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034491

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11055

Flygut - An atlas of the Drosophila adult midgut

FBgn0034491

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Hsl

Transgenic constructs containing regulatory region of Hsl

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2R)Exel7162

(Ryder, 2004.4.26)

Inferred from location ( 2 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

Hsl¹

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Hsl^GD7180

viable, with Scer\GAL4^Mef2.PR

Hsl^GD7180

viable, with Scer\GAL4^pnr-MD237

Hsl^GD7180

viable, with Scer\GAL4^tin.CΔ4

Hsl^GD7180

Other Phenotypes

Allele

decreased fecundity

Hsl¹

decreased fecundity, with Scer\GAL4^Cg.PA

Hsl^HMC05951

some die during embryonic stage

Hsl¹

some die during embryonic stage, with Scer\GAL4^Cg.PA

Hsl^HMC05951

Phenotype manifest in

Allele

embryonic/larval fat body | larval stage

Hsl^b24

lipid droplet

Hsl^b24

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (10)

Hsap\LIPE

13 of 14

Yes

Hsap\AADAC

3 of 14

Yes

Hsap\AADACL2

3 of 14

Yes

Hsap\AADACL3

3 of 14

Yes

Hsap\AADACL4

3 of 14

Yes

Hsap\NCEH1

3 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (15)

Rnor\Lipe

13 of 14

Yes

Rnor\Aadacl2

3 of 14

Yes

Rnor\Aadacl3

3 of 14

Yes

Rnor\Aadacl4

3 of 14

Yes

Rnor\Aadac

3 of 14

Yes

Rnor\LOC691196

3 of 14

Yes

Rnor\Nceh1

3 of 14

Yes

Rnor\RGD1308878

3 of 14

Yes

Rnor\RGD1559622

3 of 14

Yes

Rnor\RGD1559644

3 of 14

Yes

Rnor\RGD1560324

3 of 14

Yes

Rnor\RGD1563334

3 of 14

Yes

Rnor\RGD1560162

2 of 14

Yes

Rnor\RGD1561998

2 of 14

Yes

Rnor\Afmid

1 of 14

Mus musculus (laboratory mouse) (17)

Mmus\Lipe

13 of 14

Yes

Mmus\Aadacl2fm1

3 of 14

Yes

Mmus\Aadacl2fm3

3 of 14

Yes

Mmus\Aadacl2

3 of 14

Yes

Mmus\Aadacl3

3 of 14

Yes

Mmus\Aadacl4fm1

3 of 14

Yes

Mmus\Aadacl4fm2

3 of 14

Yes

Mmus\AAdacl4fm3

3 of 14

Yes

Mmus\Aadacl4fm4

3 of 14

Yes

Mmus\Aadacl4fm5

3 of 14

Yes

Mmus\Aadac

3 of 14

Yes

Mmus\Nceh1

3 of 14

Yes

Mmus\Aadacl2fm2

2 of 14

Yes

Mmus\Aadacl4

2 of 14

Yes

Mmus\Afmid

1 of 14

Mmus\Gm5709

1 of 14

Yes

Mmus\Gm16527

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (7)

Xtro\lipe

10 of 13

Yes

Xtro\aadacl3

2 of 13

Yes

Xtro\aadacl4

2 of 13

Yes

Xtro\aadac

2 of 13

Yes

Xtro\nceh1

2 of 13

Yes

Xtro\capn3

1 of 13

Xtro\fntb

1 of 13

Danio rerio (Zebrafish) (7)

Drer\lipea

14 of 14

Yes

Drer\lipeb

12 of 14

Yes

Drer\aadac

3 of 14

Yes

Drer\aadacl4

3 of 14

Yes

Drer\nceh1a

3 of 14

Yes

Drer\nceh1b.1

3 of 14

Yes

Drer\LOC797436

2 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (14)

Cele\hosl-1

13 of 14

Yes

Cele\F16F9.4

3 of 14

Yes

Cele\T09B9.1

3 of 14

Yes

Cele\trcs-1

3 of 14

Yes

Cele\nceh-1

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (6)

Agam\AgaP_AGAP002567

12 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (22)

Atha\AT1G49640

4 of 13

Yes

Atha\AT1G19190

3 of 13

Yes

Atha\AT1G47480

3 of 13

Yes

Atha\AT1G49650

3 of 13

Yes

Atha\AT1G68620

3 of 13

Yes

Atha\AT2G03550

3 of 13

Yes

Atha\AT2G45600

3 of 13

Yes

Atha\AT2G45610

3 of 13

Yes

Atha\AT3G27320

3 of 13

Yes

Atha\AT5G06570

3 of 13

Yes

Atha\CXE5

3 of 13

Yes

Atha\CXE12

3 of 13

Yes

Atha\CXE13

3 of 13

Yes

Atha\CXE16

3 of 13

Yes

Atha\CXE17

3 of 13

Yes

Atha\CXE18

3 of 13

Yes

Atha\CXE20

3 of 13

Yes

Atha\GID1A

3 of 13

Yes

Atha\GID1B

3 of 13

Yes

Atha\GID1C

3 of 13

Yes

Atha\ICME-LIKE1

1 of 13

Atha\PCME

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\SAY1

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\SPAC4A8.06c

3 of 12

Yes

Spom\SPAC1039.03

2 of 12

Yes

Spom\SPAPB1A11.02

1 of 12

Escherichia coli (enterobacterium) (1)

Ecol\aes

2 of 11

Yes

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Hsl. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (4)

α-Est5

1 of 13

Glt

1 of 13

Jhedup

1 of 13

KFase

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

LIPE; lipase E, hormone sensitive type

model of familial partial lipodystrophy type 6

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

LIPE; lipase E, hormone sensitive type

13 of 14

151750

LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 6; FPLD6

familial partial lipodystrophy type 6

AADAC; arylacetamide deacetylase

3 of 14

600338

AADACL2; arylacetamide deacetylase like 2

3 of 14

AADACL3; arylacetamide deacetylase like 3

3 of 14

AADACL4; arylacetamide deacetylase like 4

3 of 14

NCEH1; neutral cholesterol ester hydrolase 1

3 of 14

613234

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Hsl - Rab2

pull down, peptide massfingerprinting

(Gillingham et al., 2014)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Hsl

enhanceable

bmm

(Bi et al., 2012)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Bi et al., 2012)

suppressible

(Xu et al., 2021)

suppressible

(Yoshinari et al., 2021)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

62945

DroID - A comprehensive database of gene and protein interactions.

FBgn0034491

MIST (protein-protein) - An integrated Molecular Interaction Database

37289

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-90

Cytogenetic map

56F11-56F11

Sequence location

2R:20,257,650..20,261,726 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

56F11-56F11

Limits computationally determined from genome sequence between P{lacW}Ate1^k10809 and P{EP}CG10444^EP951

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

56E-56E

(Axton et al., 1994)

Experimentally Determined Recombination Data

Location

2-90

(FlyBase, 2016)

2-96.2

(Comeron et al., 2012)

(Axton et al., 1994)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (6)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

62826

w¹¹¹⁸; PBac{IT.GAL4}Hsl^0400-G4

22358

y¹ w^67c23; P{EPgy2}Hsl^EY20067

65148

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05951}attP40

VDRC

v109336

P{KK107348}VIE-260B

v18686

w¹¹¹⁸; P{GD7180}v18686

v318217

PBac{fTRG00729.sfGFP-TVPTBF}VK00033

Genomic Clones (9)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (96)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

DPiM_RE52776

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0034491

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0034491

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: CG11055 anon-56Ea

(FlyBase, 1996-)

Additional comments

Source for merge of CG11055 anon-56Ea was comparison of Figure 2. in FBrf0068407 with the corresponding region of the release 4.2 genome ( date:060307 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Hsl CG11055

(Bi et al., 2012)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

(Axton et al., 1994)

CG11055

(Toprak et al., 2020, Kolkhof et al., 2017, Sarov et al., 2016, Tsuda-Sakurai et al., 2015, Lin et al., 2014, Krahmer et al., 2013, Bi et al., 2012, Kuhnlein, 2012, Lee et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009, Liu and Lehmann, 2008, Cermelli et al., 2006, Gronke et al., 2005)

DmHSL

(Toprak et al., 2020, Kuhnlein, 2012)

HSL

(Krejčová et al., 2023, Lehmann, 2018, Park et al., 2018, Zheng et al., 2016)

Hsl

(Nguyen et al., 2024, Qian et al., 2023, Eickelberg et al., 2022, Ueda et al., 2022, Zhou et al., 2022, Heier et al., 2021, Kumar et al., 2021, Xu et al., 2021, Kierdorf et al., 2020, Lee et al., 2020, Parker et al., 2020, Sênos Demarco et al., 2020, Franchet et al., 2019, Saavedra and Perrimon, 2019, Yan et al., 2017, Clandinin and Owens, 2016-)

anon-56Ea

dHSL

(Akagi et al., 2025, Yoshinari et al., 2021, Azuma et al., 2019, Molaei et al., 2019, Lee et al., 2013, Bi et al., 2012)

dHsl

(Dayal Aggarwal et al., 2024)

dhsl

(Scopelliti et al., 2019)

hsl

(Wei et al., 2025, De Groef et al., 2024, Tran et al., 2024, Binh et al., 2022, Zhao et al., 2021, Wat et al., 2020)

Name Synonyms

Hormone sensitive lipase

(Krahmer et al., 2013)

Hormone-sensitive lipase

(Liu et al., 2019, Lee et al., 2013)

Hormone-sensitive lipase ortholog

transcription unit A

(Axton et al., 1994)

Secondary FlyBase IDs

FBgn0014915

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 45 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37289

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q7JR83

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q7JR83

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37289/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034491

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034491

FlyMine - An integrated database for Drosophila genomics

FBgn0034491

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG11055

MARRVEL_MODEL - MARRVEL (model organism gene)

37289

Linkouts

BioGRID - A database of protein and genetic interactions.

62945

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0034491

DroID - A comprehensive database of gene and protein interactions.

FBgn0034491

DRSC - Results frm RNAi screens

FBgn0034491

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Hsl_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034491

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0034491

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11055

Flygut - An atlas of the Drosophila adult midgut

FBgn0034491

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC008216

MIST (protein-protein) - An integrated Molecular Interaction Database

37289

References (80)

The following external sites may use different assemblies or annotations than FlyBase.

0.14

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