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Gene Dmel\CG13868

General Information
Symbol	Dmel\CG13868	Species	D. melanogaster
Name		Annotation symbol	CG13868
Feature type	protein_coding_gene	FlyBase ID	FBgn0034501
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	56F16-56F16	Sequence location	2R:16,196,217..16,204,415 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG13868 (FBgn0034501). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult Malpighian tubules, larval/adult fat body, adult spermathecae. Comments on Affy2 ProbeSet: ProbeSet 1638183_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG13868. Gene sequence location is 2R:16196217..16204415.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA06427 BKN24690
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 56F16-56F16   Limits computationally determined from genome sequence between P{EP}CG10444EP951 and P{EP}l(2)05510EP2587&P{lacW}rigk07917
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG13868 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone SD03066 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG13868-RA FBtr0086298  NM_137628   3918   523 CG13868-RB FBtr0301209  NM_001169744   3216   523
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG13868-PA   FBpp0085610   59.0   523   4.63     NP_611472   AAF57480 CG13868-PB   FBpp0290427   59.0   523   4.63     NP_001163215   ACZ94487
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA393019   AA567598   AA816780   AE013599 AAF57480   AE013599 ACZ94487   AI063791   AI109882   AI113386   AI135888   AI135917   AI238121   AI531799   AI532205   AW944282   AX201676   AY084205 AAL89943   BE662120   BG632784   BI162456   BI162457   BI162839   BI163825   BI164528   BI165038   BI165708   BI165792   BI168608   BI168996   BI169331   BI172376   BI173369   BI212442   BI213024   BI213034   BI215036   BI216727   BI216913   BI227570   BI228767   BI230344   BI230653   BI231420   BI231967   BI235949   BI236862   BI237278   BI237752   BI238246   BI242132   BI242309   BI242375   BI243175   BI361618   BI362656   BI363007   BI364741   BI365150   BI366708   BI367197   BI368474   BI370310   BI370549   BI371622   BI372384   BI373034   BI373630   BI373993   BI374303   BI375553   BI482639   BI563765   BI566943   BI567119   BI567874   BI569150   BI569168   BI569370   BI570245   BI570379   BI575307   BI575357   BI575775   BI576124   BI576175   BI576730   BI576965   BI577774   BI578540   BI579386   BI580000   BI581702   BI581831   BI583000   BI583437   BI584288   BI584423   BI585714   BI585929   BI587034   BI587643   BI587709   BI588124   BI589779   BI592134   BI592766   BI592768   BI593067   BI593297   BI593302   BI593336   BI593379   BI593486   BI593571   BI605834   BI606750   BI607481   BI607792   BI607886   BI608011   BI608274   BI608293   BI608986   BI609021   BI609518   BI609859   BI609937   BI610428   BI610832   BI611007   BI611068   BI611396   BI611901   BI613454   BI613591   BI615054   BI615121   BI615906   BI617135   BI617804   BI618624   BI618809   BI619109   BI619724   BI620855   BI621208   BI623385   BI624278   BI625213   BI625505   BI625870   BI627724   BI628785   BI629711   BI630131   BI631050   BI631691   BI631778   BI631860   BI631938   BI631981   BI634127   BP547714   BP555246   CL526179   CO177741   CO179397   CO196027   CO265025   CO271467   CO271578   CO275202   CO275691   CO279294   CO281291   CO282665   CO292207   CO296944   CO299075   CO300675   CO303524   CO303714   CO303747   CO306307   CO309905   CO310148   CO313963   CO318068   CO319830   CO337849   CO343278   CZ477731   CZ487783   CZ487784   EC053718   EC059831   EC064564   EC064846   EC064874   EC071606   EC075053   EC075288   EC076303   EC080455   EC081003   EC083627   EC084247   EC198214   EC199960   EC203162   EC204581   EC208955   EC215908   EC217486   EC225566   EC225748   EC232125   EC236306   EC240063   EC244605   EC245167   EC245455   EC247676   EC249153   EC249903   EC250048   EC257329   EC267054   ES690869   ES690875
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T4G0 A1ZBT2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034501    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034501 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034501 expression level Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr    13766 embryo 18-20hr    27870 embryo 20-22hr    12473 embryo 22-24hr    17800 larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day    13061 adult male 30day    10844 adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (298) embryo 02-04hr  (2967) embryo 04-06hr  (2441) embryo 06-08hr  (3635) embryo 08-10hr  (1996) embryo 10-12hr  (2017) embryo 12-14hr  (2992) embryo 14-16hr  (7428) embryo 16-18hr  (13766) embryo 18-20hr  (27870) embryo 20-22hr  (12473) embryo 22-24hr  (17800) larva L1  (3899) larva L2  (3470) larva L3 12hr old  (6125) larva L3 puffstage 1-2  (2991) larva L3 puffstage 3-6  (3247) larva L3 puffstage 7-9  (2956) white prepupae new  (3099) white prepupae 12hr  (6120) white prepupae 24hr  (3715) pupae 2d postWPP  (2720) pupae 3d postWPP  (4463) pupae 4d postWPP  (8863) adult male 01day  (8914) adult male 05day  (13061) adult male 30day  (10844) adult female 01day  (7318) adult female 05day  (3669) adult female 30day  (3722) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr  (2967) embryo 04-06hr  (2441) embryo 06-08hr  (3635) embryo 08-10hr  (1996) embryo 10-12hr  (2017) embryo 12-14hr  (2992) embryo 14-16hr  (7428) embryo 16-18hr  (13766) embryo 18-20hr  (27870) embryo 20-22hr  (12473) embryo 22-24hr  (17800) larva L1  (3899) larva L2  (3470) larva L3 12hr old  (6125) larva L3 puffstage 1-2  (2991) larva L3 puffstage 3-6  (3247) larva L3 puffstage 7-9  (2956) white prepupae new  (3099) white prepupae 12hr  (6120) white prepupae 24hr  (3715) pupae 2d postWPP  (2720) pupae 3d postWPP  (4463) pupae 4d postWPP  (8863) adult male 01day  (8914) adult male 05day  (13061) adult male 30day  (10844) adult female 01day  (7318) adult female 05day  (3669) adult female 30day  (3722) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr  (13766) embryo 18-20hr  (27870) embryo 20-22hr  (12473) embryo 22-24hr  (17800) larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day  (13061) adult male 30day  (10844) adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr    13766 embryo 18-20hr    27870 embryo 20-22hr    12473 embryo 22-24hr    17800 larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day    13061 adult male 30day    10844 adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034501 expression level Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr    13766 embryo 18-20hr    27870 embryo 20-22hr    12473 embryo 22-24hr    17800 larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day    13061 adult male 30day    10844 adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (298) embryo 02-04hr  (2967) embryo 04-06hr  (2441) embryo 06-08hr  (3635) embryo 08-10hr  (1996) embryo 10-12hr  (2017) embryo 12-14hr  (2992) embryo 14-16hr  (7428) embryo 16-18hr  (13766) embryo 18-20hr  (27870) embryo 20-22hr  (12473) embryo 22-24hr  (17800) larva L1  (3899) larva L2  (3470) larva L3 12hr old  (6125) larva L3 puffstage 1-2  (2991) larva L3 puffstage 3-6  (3247) larva L3 puffstage 7-9  (2956) white prepupae new  (3099) white prepupae 12hr  (6120) white prepupae 24hr  (3715) pupae 2d postWPP  (2720) pupae 3d postWPP  (4463) pupae 4d postWPP  (8863) adult male 01day  (8914) adult male 05day  (13061) adult male 30day  (10844) adult female 01day  (7318) adult female 05day  (3669) adult female 30day  (3722) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr  (2967) embryo 04-06hr  2441 embryo 06-08hr  (3635) embryo 08-10hr  1996 embryo 10-12hr  2017 embryo 12-14hr  (2992) embryo 14-16hr  (7428) embryo 16-18hr  (13766) embryo 18-20hr  (27870) embryo 20-22hr  (12473) embryo 22-24hr  (17800) larva L1  (3899) larva L2  (3470) larva L3 12hr old  (6125) larva L3 puffstage 1-2  (2991) larva L3 puffstage 3-6  (3247) larva L3 puffstage 7-9  (2956) white prepupae new  (3099) white prepupae 12hr  (6120) white prepupae 24hr  (3715) pupae 2d postWPP  (2720) pupae 3d postWPP  (4463) pupae 4d postWPP  (8863) adult male 01day  (8914) adult male 05day  (13061) adult male 30day  (10844) adult female 01day  (7318) adult female 05day  (3669) adult female 30day  (3722) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr  13766 embryo 18-20hr  (27870) embryo 20-22hr  12473 embryo 22-24hr  17800 larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day  13061 adult male 30day  10844 adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    298 embryo 02-04hr    2967 embryo 04-06hr    2441 embryo 06-08hr    3635 embryo 08-10hr    1996 embryo 10-12hr    2017 embryo 12-14hr    2992 embryo 14-16hr    7428 embryo 16-18hr    13766 embryo 18-20hr    27870 embryo 20-22hr    12473 embryo 22-24hr    17800 larva L1    3899 larva L2    3470 larva L3 12hr old    6125 larva L3 puffstage 1-2    2991 larva L3 puffstage 3-6    3247 larva L3 puffstage 7-9    2956 white prepupae new    3099 white prepupae 12hr    6120 white prepupae 24hr    3715 pupae 2d postWPP    2720 pupae 3d postWPP    4463 pupae 4d postWPP    8863 adult male 01day    8914 adult male 05day    13061 adult male 30day    10844 adult female 01day    7318 adult female 05day    3669 adult female 30day    3722 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034501    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034501 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult Malpighian tubules, larval/adult fat body, adult spermathecae. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034501 expression level Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034501 expression level Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.625 Larval Midgut    71.5 Larval Hindgut    90 Larval Malpighian Tubules    202.1 Larval Fat Body    134.1 Larval Salivary Gland    8.7 Larval Trachea    7.45 Larval Carcass    14.1 Adult Head    50.4 Adult Eye    23.8 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    20.2 Adult Midgut    24.1 Adult Hindgut    43.6 Adult Malpighian Tubules    267.9 Adult Fat Body    276.7 Adult Salivary Gland no informative data Adult Heart    78.675 Adult VirginFemale Spermatheca    313.7 Adult InseminatedFemale Spermatheca    366.9 Adult Ovary    8.2 Adult Testis    8 Adult Male Accessory Gland    20.2 Adult Carcass    96.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    50.4   NA  Eye    23.8   NA  Brain    no informative data   14.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    20.2   71.5  Midgut    24.1   90  Hindgut    43.6   202.1  Malpighian Tubules    267.9   134.1  Fat Body    276.7   8.7  Salivary Gland    no informative data   NA  Heart    78.675   7.45  Trachea    NA   NA  VirginFemale Spermatheca    313.7   NA  InseminatedFemale Spermatheca    366.9   NA  Ovary    8.2   NA  Testis    8   NA  Male Accessory Gland    20.2   14.1  Carcass    96.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_24
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034501 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13868-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG13868 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG13868GD8142 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG13868GD8142 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG13868GD8142
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG13868 Class Mutagen Stocks Known lesion CG13868d11451 P-element activity 1 -- CG13868EY01933 P-element activity 1 -- CG13868EY10027 P-element activity 1 Yes CG13868f05159 piggyBac transposase 1 -- CG13868MB04925 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG13868 Class Mutagen Stocks Known lesion CG13868GD8142 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8142} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG13868EY01933 NA P{EPgy2}CG13868EY10027 NA P{GSV1}EP-614EP-614 NA P{XP}CG13868d11451 NA miscellaneous insertions PBac{WH}CG13868f05159 NA insertion of enhancer trap binary system Mi{ET1}CG13868MB04925 No
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG13868 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62957 DroID - A comprehensive database of gene and protein interactions. • FBgn0034501 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37302
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12670 Dere\GG20866 Dgri\GH20060 Dmoj\GI18777 Dper\GL16835 Dpse\GA12584 Dsec\GM19791 Dsim\GD25283 Dvir\GJ21804 Dwil\GK17849 Dyak\GE13806
Curated drosophilid orthologs	Dpse\GA12584
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013987-PA Aedes aegypti (mosquito) XP_393098.1 Apis mellifera (honey bee) XP_001948819.1 Acyrthosiphon pisum (pea aphid) BGIBMGA009101-PA Bombyx mori (silk worm) CPIJ009026 Culex pipens (mosquito) ISCW003568-PA Ixodes scapularis (deer tick) XP_001602432.1 Nasonia vitripennis (wasp) PHUM008641-PA Pediculus humanus (human body louse) XP_967856.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13656 NV15028 LH20949 ISCW003568 FBgn0231457 FBgn0219848 FBgn0208922 FBgn0196593 FBgn0174688 JGI_V11_299881 FBgn0072630 FBgn0154439 FBgn0141516 FBgn0127524 FBgn0113052 FBgn0089706 CPIJ009026 BGIBMGA009101 BGIBMGA009102 ACYPI004689 GB17087 AAEL013987 PHUM333160 GLEAN_05104
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	15542 y1 w67c23; P{EPgy2}CG13868EY01933 24595 w1118; Mi{ET1}CG13868MB04925 CG8920MB04925 17634 y1 w67c23; P{EPgy2}CG13868EY10027 CG8920EY10027/CyO
Harvard	- P{XP}CG13868d11451 - PBac{WH}CG13868f05159
VDRC	v32075 w1118 P{GD8142}v32075
Genomic Clones ( 2 )
	BACR10H12 BACR48L22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 215 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD03066
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03771 GH09002 GH09268 GH14120 HL01514 LD03734 LD10336 RE02082 RE03338 RE10139 RE14372 RE18326 RE18338 RE21227 RE21482 RE23960 RE26410 RE33474 RE34038 RE34653 RE39680 RE40739 RE50381 RE54449 RE58550 RE60246 RE60972 RE61859 RE63401 RE71515 RE72421 RE73411 RE74118 RH03265 RH09758 RH10545 RH10547 RH10958 RH11301 RH11308 RH11345 RH11407 RH11561 RH11679 RH11731 RH11862 RH12137 RH12469 RH12490 RH13713 RH13750 RH14313 RH14701 RH14788 RH15922 RH16753 RH17075 RH17168 RH17595 RH18360 RH19239 RH19640 RH21432 RH22048 RH23366 RH23622 RH25349 RH25633 RH27294 RH28377 RH28562 RH29194 RH30921 RH32627 RH32682 RH33354 RH37343 RH42778 RH44574 RH44659 RH45804 RH47371 RH48247 RH49492 RH49727 RH50080 RH50819 RH52104 RH52517 RH55619 RH57530 RH58617 RH59112 RH60454 RH61321 RH61424 RH61625 RH61673 RH63814 RH65503 RH66371 RH69120 RH71820 RH73552 RH74558 SD03613
Other clones	14215 14993 20260 31780 39479 45015 54112 71384 74529 81527 81961 97235 102011 102277 102969 106001 108252 121658 144336 162832 165739 176047 214435.72 569699 bs24b12 CK01.11C.F9 CK01.32C.E2 CK01.67B.G6 CK01.111A.G7 CK01.131A.D5 CK01.147C.A4 CK01.169A.G7 CK01.169C.G7 EC053718 EK000225 EK054159 EK059305 EK103528 EK103928 EK116723 EK118318 EK133958 EK141258 EK156362 EK160931 EK174443 EK179016 EK199448 EK215459 EK219730 EK220609 EK234520 EK241939 EK242615 EK242660 EK250742 EK270244 EK280964 EN15423 EP16445 FGH119H10 FGM234C03 GH13801 GH13839 RE01768 RE04227 RE04840 RE05650 RE05750 RE09421 RE09942 RE10471 RE14838 RE16273 RE17535 RE24403 RE24656 RE25153 RE31916 RE32987 RE39377 RE39609 RE45916 RE47272 RE47713 RE49914 RE52302 RE52993 RE56775 RE57212 RE59333 RE61483 RE65353 RH01321 RH01332 RH01459 RH02534 RH02691 RH30582 RH32084 RH33674 RH34468 RH36751 RH36973 RH38577 RH42613 RH61524 RH65948
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034501 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37302
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG13868 anon-WO0153538.60 (FlyBase, 1996-)
Additional comments	Source for merge of CG13868 anon-WO0153538.60 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137628 NM_001169744 RefSeq (Proteins) • NP_611472 NP_001163215 DDBJ / EMBL / GenBank • AAF57480 AAL89943 ACZ94487 AI531799 AW944282 AX201676 AY084205 BE662120 CL526179 CZ477731 CZ487783 CZ487784 Entrez Gene - A searchable database of RefSeq genes. • 37302 UniProtKB/TrEMBL • A1ZBT2 Q8T4G0
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 62957 DroID - A comprehensive database of gene and protein interactions. • FBgn0034501 DRSC - Results from RNAi screens. • FBgn0034501 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034501 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13868-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034501 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37302 InParanoid A subset of ortholog calls from InParanoid. • AAEL013987-PA Aedes aegypti (mosquito) XP_393098.1 Apis mellifera (honey bee) XP_001948819.1 Acyrthosiphon pisum (pea aphid) BGIBMGA009101-PA Bombyx mori (silk worm) CPIJ009026 Culex pipens (mosquito) ISCW003568-PA Ixodes scapularis (deer tick) XP_001602432.1 Nasonia vitripennis (wasp) PHUM008641-PA Pediculus humanus (human body louse) XP_967856.1 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37302 modMine - Data generated by the modENCODE project. • FBgn0034501 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13656 NV15028 LH20949 ISCW003568 FBgn0231457 FBgn0219848 FBgn0208922 FBgn0196593 FBgn0174688 JGI_V11_299881 FBgn0072630 FBgn0154439 FBgn0141516 FBgn0127524 FBgn0113052 FBgn0089706 CPIJ009026 BGIBMGA009101 BGIBMGA009102 ACYPI004689 GB17087 AAEL013987 PHUM333160 GLEAN_05104
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	anon-WO0153538.60   CG13868 (Quinones-Coello, 2007, Molnar et al., 2006, Kadener et al., 2007, Chang et al., 2008, Li et al., 2007)
Name Synonym
Secondary FlyBase IDs
	FBgn0045891
References ( 18 )
Research paper	Chang et al., 2008, PLoS ONE 3(9): e3209 Modeling spinal muscular atrophy in Drosophila. [FBrf0206033] Kadener et al., 2007, Genes Dev. 21(13): 1675--1686 Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component. [FBrf0200951] Li et al., 2007, J. Biol. Chem. 282(52): 37605--37617 Identification and characterization of a juvenile hormone response element and its binding proteins. [FBrf0202965] Molnar et al., 2006, Genetics 174(3): 1635--1659 A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. [FBrf0195387] Bianchi-Frias et al., 2004, PLoS Biol. 2(7): 0975--0990 Hairy transcriptional repression targets and cofactor recruitment in Drosophila. [FBrf0179136]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Quinones-Coello, 2007, Genetics 175(3): Supplemental Table 1. List of genes associated with protein or enhancer traps. [FBrf0200393] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	BDGP TI submission, 2007.10.9, batch761.xml batch761.xml [FBrf0200260] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Patent	Greenspan and Edelman, 2001.7.26, World Patent 0153538-A: Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of Alzheimer's disease. [FBrf0141237]