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Gene Dmel\maf-S

General Information
Symbol	Dmel\maf-S	Species	D. melanogaster
Name	maf-S	Annotation symbol	CG9954
Feature type	protein_coding_gene	FlyBase ID	FBgn0034534
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	maf2
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	57A8-57A8	Sequence location	2R:16,528,481..16,529,173 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene maf-S is referred to in FlyBase by the symbol Dmel\maf-S (CG9954, FBgn0034534). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein heterodimerization activity. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; head development; autophagic cell death; salivary gland cell autophagic cell death. 8 alleles are reported. The phenotypes of these alleles are annotated with: median tooth; lateral process. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Basic leucine zipper domain, Maf-type; Basic-leucine zipper domain; Eukaryotic transcription factor, Skn-1-like, DNA-binding; Transcription factor Maf. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1635314_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of maf-S. Gene sequence location is 2R:16528476..16529173.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Transcripts maf-S-RB Polypeptides maf-S-PB
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 57A8-57A8   Limits computationally determined from genome sequence between P{EP}l(2)05510EP2587&P{lacW}rigk07917 and P{lacW}l(2)k02206k02206
Experimentally Determined Cytological Location
Cytogenetic map Notes References 57A-57A   (determined by in situ hybridisation)   (Vani et al., 1997)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\maf-S for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) maf-S-RA FBtr0086230  NM_137656   631   132 maf-S-RB FBtr0342716     646   137
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein maf-S-PA   FBpp0085544   15.7   132   9.22     NP_611500   AAF57439 maf-S-PB   FBpp0309590   16.3   137   8.94
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Basic leucine zipper domain, Maf-type (IPR004826) Basic-leucine zipper domain (IPR004827) Eukaryotic transcription factor, Skn-1-like, DNA-binding (IPR008917) Transcription factor Maf (IPR024874)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF57439   AF171827   AI062774   AI062850   AI238611   AI296134   AY231837   BI611815   BI611903   BI620268   BP540265   BP543129   BP545237   BP546695   BP549740   BP553059   BP553387   BP555801   BP558672   BT023717   CK659373   CO181029   CO183019   CO296435   EC087162
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q4QPP9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Veraksa et al., 2000) embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 8   cephalic furrow   (Veraksa et al., 2000) mesoderm   (Veraksa et al., 2000) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) fat body/gonad primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 11 -- 17   embryonic/larval midgut primordium   (Veraksa et al., 2000) embryonic intercalary segment   (Veraksa et al., 2000) presumptive embryonic/larval central nervous system   (Veraksa et al., 2000) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) gonad   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
	maf-S expression is ubiquitous in embryos at all stages, with enrichment in specific spatiotemporal areas. At embryonic stage 8, transcript levels are slightly higher in the mesoderm and the cephalic furrow than in the rest of the embryo. Starting at embryonic stage 11, expression is slightly enriched in the anterior and posterior midgut, in the central nervous system, and in the At stage 13, expression is slightly higher in the midgut, central nervous system, in the involuting intercalary segment that gives rise to the ventral pharynx. (Veraksa et al., 2000)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval hindgut, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye    1516.725 Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop    1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland    1222.1 Adult Heart    564.15 Adult VirginFemale Spermatheca    1001.5 Adult InseminatedFemale Spermatheca    1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland    1884.4 Adult Carcass    654.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (569.425) Larval Midgut  (614.5) Larval Hindgut    432.5 Larval Malpighian Tubules  (666.4) Larval Fat Body  (719.1) Larval Salivary Gland  (564.5) Larval Trachea  (571.65) Larval Carcass    313.6 Adult Head  (998.1) Adult Eye  (1516.725) Adult Brain  (936) Adult Thoracic-Abdominal Ganglion  (928.8) Adult Crop  (1001.2) Adult Midgut  (913.6) Adult Hindgut  (982.6) Adult Malpighian Tubules  (677.9) Adult Fat Body  500.3 Adult Salivary Gland  (1222.1) Adult Heart  (564.15) Adult VirginFemale Spermatheca  (1001.5) Adult InseminatedFemale Spermatheca  (1031.5) Adult Ovary  528.7 Adult Testis  (540.2) Adult Male Accessory Gland  (1884.4) Adult Carcass  (654.1) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye  (1516.725) Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop  1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland  (1222.1) Adult Heart    564.15 Adult VirginFemale Spermatheca  1001.5 Adult InseminatedFemale Spermatheca  1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland  (1884.4) Adult Carcass    654.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye    1516.725 Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop    1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland    1222.1 Adult Heart    564.15 Adult VirginFemale Spermatheca    1001.5 Adult InseminatedFemale Spermatheca    1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland    1884.4 Adult Carcass    654.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye    1516.725 Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop    1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland    1222.1 Adult Heart    564.15 Adult VirginFemale Spermatheca    1001.5 Adult InseminatedFemale Spermatheca    1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland    1884.4 Adult Carcass    654.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  569.425 Larval Midgut  614.5 Larval Hindgut    432.5 Larval Malpighian Tubules  666.4 Larval Fat Body  719.1 Larval Salivary Gland  564.5 Larval Trachea  571.65 Larval Carcass    313.6 Adult Head  (998.1) Adult Eye  (1516.725) Adult Brain  (936) Adult Thoracic-Abdominal Ganglion  (928.8) Adult Crop  (1001.2) Adult Midgut  (913.6) Adult Hindgut  (982.6) Adult Malpighian Tubules  677.9 Adult Fat Body  500.3 Adult Salivary Gland  (1222.1) Adult Heart  564.15 Adult VirginFemale Spermatheca  (1001.5) Adult InseminatedFemale Spermatheca  (1031.5) Adult Ovary  528.7 Adult Testis  540.2 Adult Male Accessory Gland  (1884.4) Adult Carcass  654.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye  1516.725 Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop  1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland  1222.1 Adult Heart    564.15 Adult VirginFemale Spermatheca  1001.5 Adult InseminatedFemale Spermatheca  1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland  (1884.4) Adult Carcass    654.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    569.425 Larval Midgut    614.5 Larval Hindgut    432.5 Larval Malpighian Tubules    666.4 Larval Fat Body    719.1 Larval Salivary Gland    564.5 Larval Trachea    571.65 Larval Carcass    313.6 Adult Head    998.1 Adult Eye    1516.725 Adult Brain    936 Adult Thoracic-Abdominal Ganglion    928.8 Adult Crop    1001.2 Adult Midgut    913.6 Adult Hindgut    982.6 Adult Malpighian Tubules    677.9 Adult Fat Body    500.3 Adult Salivary Gland    1222.1 Adult Heart    564.15 Adult VirginFemale Spermatheca    1001.5 Adult InseminatedFemale Spermatheca    1031.5 Adult Ovary    528.7 Adult Testis    540.2 Adult Male Accessory Gland    1884.4 Adult Carcass    654.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    998.1   NA  Eye    1516.725   NA  Brain    936   569.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    928.8   NA  Crop    1001.2   614.5  Midgut    913.6   432.5  Hindgut    982.6   666.4  Malpighian Tubules    677.9   719.1  Fat Body    500.3   564.5  Salivary Gland    1222.1   NA  Heart    564.15   571.65  Trachea    NA   NA  VirginFemale Spermatheca    1001.5   NA  InseminatedFemale Spermatheca    1031.5   NA  Ovary    528.7   NA  Testis    540.2   NA  Male Accessory Gland    1884.4   313.6  Carcass    654.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3    105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female    134 head, virgin 20-day female    87 head, mated 1-day female    106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male    135 head, mated 4-day male    141 head, mated 20-day male    196 salivary gland, larvae L3 wandering    77 salivary gland, white prepupae    206 digestive system, larvae L3 wandering    212 digestive system, 1-day adult    129 digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8    183 carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female    105 ovary, mated 4-day female    103 testis, mated 4-day male    195 accessory gland, mated 4-day male    208 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (95) central nervous system, larvae L3  (105) central nervous system, pupae P8  (58) head, virgin 1-day female  (85) head, virgin 4-day female  (134) head, virgin 20-day female  (87) head, mated 1-day female  (106) head, mated 4-day female  (100) head, mated 20-day female  (80) head, mated 1-day male  (135) head, mated 4-day male  (141) head, mated 20-day male  (196) salivary gland, larvae L3 wandering  (77) salivary gland, white prepupae  (206) digestive system, larvae L3 wandering  (212) digestive system, 1-day adult  (129) digestive system, 4-day adult  (89) digestive system, 20-day adult  (92) fat body, larvae L3 wandering  (39) fat body, white prepupae  (88) fat body, pupae P8  (183) carcass, larvae L3 wandering  (94) carcass, 1-day adult  (66) carcass, 4-day adult  (70) carcass, 20-day adult  (87) ovary, virgin 4-day female  (105) ovary, mated 4-day female  (103) testis, mated 4-day male  (195) accessory gland, mated 4-day male  (208) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3  105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female  (134) head, virgin 20-day female    87 head, mated 1-day female  106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male  (135) head, mated 4-day male  (141) head, mated 20-day male  (196) salivary gland, larvae L3 wandering    77 salivary gland, white prepupae  (206) digestive system, larvae L3 wandering  (212) digestive system, 1-day adult  (129) digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8  (183) carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female  105 ovary, mated 4-day female  103 testis, mated 4-day male  (195) accessory gland, mated 4-day male  (208) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3    105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female    134 head, virgin 20-day female    87 head, mated 1-day female    106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male    135 head, mated 4-day male    141 head, mated 20-day male    196 salivary gland, larvae L3 wandering    77 salivary gland, white prepupae    206 digestive system, larvae L3 wandering    212 digestive system, 1-day adult    129 digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8    183 carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female    105 ovary, mated 4-day female    103 testis, mated 4-day male    195 accessory gland, mated 4-day male    208 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3    105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female    134 head, virgin 20-day female    87 head, mated 1-day female    106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male    135 head, mated 4-day male    141 head, mated 20-day male    196 salivary gland, larvae L3 wandering    77 salivary gland, white prepupae    206 digestive system, larvae L3 wandering    212 digestive system, 1-day adult    129 digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8    183 carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female    105 ovary, mated 4-day female    103 testis, mated 4-day male    195 accessory gland, mated 4-day male    208 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (95) central nervous system, larvae L3  (105) central nervous system, pupae P8  (58) head, virgin 1-day female  (85) head, virgin 4-day female  (134) head, virgin 20-day female  (87) head, mated 1-day female  (106) head, mated 4-day female  (100) head, mated 20-day female  (80) head, mated 1-day male  (135) head, mated 4-day male  (141) head, mated 20-day male  (196) salivary gland, larvae L3 wandering  (77) salivary gland, white prepupae  (206) digestive system, larvae L3 wandering  (212) digestive system, 1-day adult  (129) digestive system, 4-day adult  (89) digestive system, 20-day adult  (92) fat body, larvae L3 wandering  (39) fat body, white prepupae  (88) fat body, pupae P8  (183) carcass, larvae L3 wandering  (94) carcass, 1-day adult  (66) carcass, 4-day adult  (70) carcass, 20-day adult  (87) ovary, virgin 4-day female  (105) ovary, mated 4-day female  (103) testis, mated 4-day male  (195) accessory gland, mated 4-day male  (208) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3  105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female  134 head, virgin 20-day female    87 head, mated 1-day female  106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male  135 head, mated 4-day male  141 head, mated 20-day male  (196) salivary gland, larvae L3 wandering    77 salivary gland, white prepupae  (206) digestive system, larvae L3 wandering  (212) digestive system, 1-day adult  129 digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8  (183) carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female  105 ovary, mated 4-day female  103 testis, mated 4-day male  (195) accessory gland, mated 4-day male  (208) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    95 central nervous system, larvae L3    105 central nervous system, pupae P8    58 head, virgin 1-day female    85 head, virgin 4-day female    134 head, virgin 20-day female    87 head, mated 1-day female    106 head, mated 4-day female    100 head, mated 20-day female    80 head, mated 1-day male    135 head, mated 4-day male    141 head, mated 20-day male    196 salivary gland, larvae L3 wandering    77 salivary gland, white prepupae    206 digestive system, larvae L3 wandering    212 digestive system, 1-day adult    129 digestive system, 4-day adult    89 digestive system, 20-day adult    92 fat body, larvae L3 wandering    39 fat body, white prepupae    88 fat body, pupae P8    183 carcass, larvae L3 wandering    94 carcass, 1-day adult    66 carcass, 4-day adult    70 carcass, 20-day adult    87 ovary, virgin 4-day female    105 ovary, mated 4-day female    103 testis, mated 4-day male    195 accessory gland, mated 4-day male    208 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr    140 embryo 06-08hr    118 embryo 08-10hr    123 embryo 10-12hr    129 embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr    114 larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (61) embryo 02-04hr  (94) embryo 04-06hr  (140) embryo 06-08hr  (118) embryo 08-10hr  (123) embryo 10-12hr  (129) embryo 12-14hr  (88) embryo 14-16hr  (65) embryo 16-18hr  (74) embryo 18-20hr  (87) embryo 20-22hr  (92) embryo 22-24hr  (114) larva L1  (70) larva L2  (44) larva L3 12hr old  (31) larva L3 puffstage 1-2  (54) larva L3 puffstage 3-6  (78) larva L3 puffstage 7-9  (100) white prepupae new  (86) white prepupae 12hr  (95) white prepupae 24hr  (94) pupae 2d postWPP  (97) pupae 3d postWPP  (61) pupae 4d postWPP  (48) adult male 01day  (76) adult male 05day  (87) adult male 30day  (82) adult female 01day  (46) adult female 05day  (61) adult female 30day  (55) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr  (140) embryo 06-08hr  (118) embryo 08-10hr  (123) embryo 10-12hr  (129) embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr  (114) larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr    140 embryo 06-08hr    118 embryo 08-10hr    123 embryo 10-12hr    129 embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr    114 larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr    140 embryo 06-08hr    118 embryo 08-10hr    123 embryo 10-12hr    129 embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr    114 larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (61) embryo 02-04hr  (94) embryo 04-06hr  (140) embryo 06-08hr  (118) embryo 08-10hr  (123) embryo 10-12hr  (129) embryo 12-14hr  (88) embryo 14-16hr  (65) embryo 16-18hr  (74) embryo 18-20hr  (87) embryo 20-22hr  (92) embryo 22-24hr  (114) larva L1  (70) larva L2  (44) larva L3 12hr old  31 larva L3 puffstage 1-2  (54) larva L3 puffstage 3-6  (78) larva L3 puffstage 7-9  (100) white prepupae new  (86) white prepupae 12hr  (95) white prepupae 24hr  (94) pupae 2d postWPP  (97) pupae 3d postWPP  (61) pupae 4d postWPP  (48) adult male 01day  (76) adult male 05day  (87) adult male 30day  (82) adult female 01day  (46) adult female 05day  (61) adult female 30day  (55) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr  140 embryo 06-08hr  118 embryo 08-10hr  123 embryo 10-12hr  129 embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr  114 larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    61 embryo 02-04hr    94 embryo 04-06hr    140 embryo 06-08hr    118 embryo 08-10hr    123 embryo 10-12hr    129 embryo 12-14hr    88 embryo 14-16hr    65 embryo 16-18hr    74 embryo 18-20hr    87 embryo 20-22hr    92 embryo 22-24hr    114 larva L1    70 larva L2    44 larva L3 12hr old    31 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    78 larva L3 puffstage 7-9    100 white prepupae new    86 white prepupae 12hr    95 white prepupae 24hr    94 pupae 2d postWPP    97 pupae 3d postWPP    61 pupae 4d postWPP    48 adult male 01day    76 adult male 05day    87 adult male 30day    82 adult female 01day    46 adult female 05day    61 adult female 30day    55 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    349 Schneider line 2 Sg4    89 embryonic 1182-4H    202 embryonic GM2    137 embryonic Kc167    116 embryonic S1    258 embryonic S3    65 leg disc CME L1    120 wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9    167 wing disc ML-DmD16-c3    99 wing disc ML-DmD21    295 wing disc ML-DmD32    95 haltere disc ML-DmD17-c3    113 eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5    132 mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1    110 CNS ML-DmBG2-c2    109 tumorous blood cells mbn2    59 ovary fGS/OSS    312 ovary OSC    179 ovary OSS    100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (349) Schneider line 2 Sg4  (89) embryonic 1182-4H  (202) embryonic GM2  (137) embryonic Kc167  (116) embryonic S1  (258) embryonic S3  (65) leg disc CME L1  (120) wing disc CME-W2  (51) wing disc ML-DmD8  (56) wing disc ML-DmD9  (167) wing disc ML-DmD16-c3  (99) wing disc ML-DmD21  (295) wing disc ML-DmD32  (95) haltere disc ML-DmD17-c3  (113) eye-antennal disc ML-DmD11  (86) antennal disc ML-DmD20-c5  (132) mixed discs ML-DmD4-c1  (82) CNS ML-DmBG1-c1  (110) CNS ML-DmBG2-c2  (109) tumorous blood cells mbn2  (59) ovary fGS/OSS  (312) ovary OSC  (179) ovary OSS  (100) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (349) Schneider line 2 Sg4    89 embryonic 1182-4H  (202) embryonic GM2  (137) embryonic Kc167  (116) embryonic S1  (258) embryonic S3    65 leg disc CME L1  (120) wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9  (167) wing disc ML-DmD16-c3    99 wing disc ML-DmD21  (295) wing disc ML-DmD32    95 haltere disc ML-DmD17-c3  (113) eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5  (132) mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1  (110) CNS ML-DmBG2-c2  (109) tumorous blood cells mbn2    59 ovary fGS/OSS  (312) ovary OSC  (179) ovary OSS    100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    349 Schneider line 2 Sg4    89 embryonic 1182-4H    202 embryonic GM2    137 embryonic Kc167    116 embryonic S1    258 embryonic S3    65 leg disc CME L1    120 wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9    167 wing disc ML-DmD16-c3    99 wing disc ML-DmD21    295 wing disc ML-DmD32    95 haltere disc ML-DmD17-c3    113 eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5    132 mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1    110 CNS ML-DmBG2-c2    109 tumorous blood cells mbn2    59 ovary fGS/OSS    312 ovary OSC    179 ovary OSS    100 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    349 Schneider line 2 Sg4    89 embryonic 1182-4H    202 embryonic GM2    137 embryonic Kc167    116 embryonic S1    258 embryonic S3    65 leg disc CME L1    120 wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9    167 wing disc ML-DmD16-c3    99 wing disc ML-DmD21    295 wing disc ML-DmD32    95 haltere disc ML-DmD17-c3    113 eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5    132 mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1    110 CNS ML-DmBG2-c2    109 tumorous blood cells mbn2    59 ovary fGS/OSS    312 ovary OSC    179 ovary OSS    100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (349) Schneider line 2 Sg4  (89) embryonic 1182-4H  (202) embryonic GM2  (137) embryonic Kc167  (116) embryonic S1  (258) embryonic S3  (65) leg disc CME L1  (120) wing disc CME-W2  (51) wing disc ML-DmD8  (56) wing disc ML-DmD9  (167) wing disc ML-DmD16-c3  (99) wing disc ML-DmD21  (295) wing disc ML-DmD32  (95) haltere disc ML-DmD17-c3  (113) eye-antennal disc ML-DmD11  (86) antennal disc ML-DmD20-c5  (132) mixed discs ML-DmD4-c1  (82) CNS ML-DmBG1-c1  (110) CNS ML-DmBG2-c2  (109) tumorous blood cells mbn2  (59) ovary fGS/OSS  (312) ovary OSC  (179) ovary OSS  (100) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (349) Schneider line 2 Sg4    89 embryonic 1182-4H  (202) embryonic GM2  137 embryonic Kc167  116 embryonic S1  (258) embryonic S3    65 leg disc CME L1  120 wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9  (167) wing disc ML-DmD16-c3    99 wing disc ML-DmD21  (295) wing disc ML-DmD32    95 haltere disc ML-DmD17-c3  113 eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5  132 mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1  110 CNS ML-DmBG2-c2  109 tumorous blood cells mbn2    59 ovary fGS/OSS  (312) ovary OSC  (179) ovary OSS    100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    349 Schneider line 2 Sg4    89 embryonic 1182-4H    202 embryonic GM2    137 embryonic Kc167    116 embryonic S1    258 embryonic S3    65 leg disc CME L1    120 wing disc CME-W2    51 wing disc ML-DmD8    56 wing disc ML-DmD9    167 wing disc ML-DmD16-c3    99 wing disc ML-DmD21    295 wing disc ML-DmD32    95 haltere disc ML-DmD17-c3    113 eye-antennal disc ML-DmD11    86 antennal disc ML-DmD20-c5    132 mixed discs ML-DmD4-c1    82 CNS ML-DmBG1-c1    110 CNS ML-DmBG2-c2    109 tumorous blood cells mbn2    59 ovary fGS/OSS    312 ovary OSC    179 ovary OSS    100 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    131 cold shock, 4-day adult    110 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult    111 Copper 0.5 mM 12 hrs, larvae L3    123 Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult    112 Ethanol 2.5% 3 hrs, larvae L3    113 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    139 Caffeine 25 mg/ml 48 hrs, 4-day adult    108 Paraquat 5 mM 48 hrs, 4-day adult    125 Paraquat 10 mM 48 hrs, 4-day adult    108 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (131) cold shock, 4-day adult  (110) heat shock, 4-day adult  (76) Cadmium 50 mM 6 hrs, larvae L3  (64) Cadmium 50 mM 12 hrs, larvae L3  (91) Cadmium 50 mM 48 hrs, 4-day adult  (63) Cadmium 100 mM 48 hrs, 4-day adult  (111) Copper 0.5 mM 12 hrs, larvae L3  (123) Copper 15 mM 48 hrs, 4-day adult  (88) Zinc 5 mM 12 hrs, larvae L3  (87) Zinc 4.5 mM 48 hrs, 4-day adult  (112) Ethanol 2.5% 3 hrs, larvae L3  (113) Ethanol 5% 3 hrs, larvae L3  (84) Ethanol 10% 3 hrs, larvae L3  (55) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (73) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (139) Caffeine 25 mg/ml 48 hrs, 4-day adult  (108) Paraquat 5 mM 48 hrs, 4-day adult  (125) Paraquat 10 mM 48 hrs, 4-day adult  (108) Rotenone 2 μg 12 hrs, larvae L3  (68) Rotenone 8 μg 12 hrs, larvae L3  (70) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (131) cold shock, 4-day adult  (110) heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult  (111) Copper 0.5 mM 12 hrs, larvae L3  (123) Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult  (112) Ethanol 2.5% 3 hrs, larvae L3  (113) Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (139) Caffeine 25 mg/ml 48 hrs, 4-day adult  (108) Paraquat 5 mM 48 hrs, 4-day adult  (125) Paraquat 10 mM 48 hrs, 4-day adult  (108) Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    131 cold shock, 4-day adult    110 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult    111 Copper 0.5 mM 12 hrs, larvae L3    123 Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult    112 Ethanol 2.5% 3 hrs, larvae L3    113 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    139 Caffeine 25 mg/ml 48 hrs, 4-day adult    108 Paraquat 5 mM 48 hrs, 4-day adult    125 Paraquat 10 mM 48 hrs, 4-day adult    108 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    131 cold shock, 4-day adult    110 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult    111 Copper 0.5 mM 12 hrs, larvae L3    123 Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult    112 Ethanol 2.5% 3 hrs, larvae L3    113 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    139 Caffeine 25 mg/ml 48 hrs, 4-day adult    108 Paraquat 5 mM 48 hrs, 4-day adult    125 Paraquat 10 mM 48 hrs, 4-day adult    108 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (131) cold shock, 4-day adult  (110) heat shock, 4-day adult  (76) Cadmium 50 mM 6 hrs, larvae L3  (64) Cadmium 50 mM 12 hrs, larvae L3  (91) Cadmium 50 mM 48 hrs, 4-day adult  (63) Cadmium 100 mM 48 hrs, 4-day adult  (111) Copper 0.5 mM 12 hrs, larvae L3  (123) Copper 15 mM 48 hrs, 4-day adult  (88) Zinc 5 mM 12 hrs, larvae L3  (87) Zinc 4.5 mM 48 hrs, 4-day adult  (112) Ethanol 2.5% 3 hrs, larvae L3  (113) Ethanol 5% 3 hrs, larvae L3  (84) Ethanol 10% 3 hrs, larvae L3  (55) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (73) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (139) Caffeine 25 mg/ml 48 hrs, 4-day adult  (108) Paraquat 5 mM 48 hrs, 4-day adult  (125) Paraquat 10 mM 48 hrs, 4-day adult  (108) Rotenone 2 μg 12 hrs, larvae L3  (68) Rotenone 8 μg 12 hrs, larvae L3  (70) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  131 cold shock, 4-day adult  110 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult  111 Copper 0.5 mM 12 hrs, larvae L3  123 Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult  112 Ethanol 2.5% 3 hrs, larvae L3  113 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  139 Caffeine 25 mg/ml 48 hrs, 4-day adult  108 Paraquat 5 mM 48 hrs, 4-day adult  125 Paraquat 10 mM 48 hrs, 4-day adult  108 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    131 cold shock, 4-day adult    110 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    91 Cadmium 50 mM 48 hrs, 4-day adult    63 Cadmium 100 mM 48 hrs, 4-day adult    111 Copper 0.5 mM 12 hrs, larvae L3    123 Copper 15 mM 48 hrs, 4-day adult    88 Zinc 5 mM 12 hrs, larvae L3    87 Zinc 4.5 mM 48 hrs, 4-day adult    112 Ethanol 2.5% 3 hrs, larvae L3    113 Ethanol 5% 3 hrs, larvae L3    84 Ethanol 10% 3 hrs, larvae L3    55 Caffeine 1.5 mg/ml 4 hrs, larvae L3    73 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    139 Caffeine 25 mg/ml 48 hrs, 4-day adult    108 Paraquat 5 mM 48 hrs, 4-day adult    125 Paraquat 10 mM 48 hrs, 4-day adult    108 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    70 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_27 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • GH02096 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034534 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9954-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 maf-SGD4373 Phenotype manifest in Allele embryonic/larval pharynx | ventral maf-SdsRNA.cVa lateral process maf-SdsRNA.cVa median tooth maf-SdsRNA.cVa mouth hooks | supernumerary maf-SdsRNA.cVa
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of maf-S Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of maf-S Class Mutagen Stocks Known lesion maf-SGD4373 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes maf-SHMS02020 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes maf-SJF02008 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes maf-ST:Avic\GFP-SF,T:Zzzz\FLAG,T:Zzzz\PSP.CS,T:Zzzz\TEV.CS,T:Zzzz\BLRP in vitro construct - coding region fusion 1 Yes maf-SdsRNA.cVa in vitro construct - RNAi 0 -- maf-SKK102044 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes maf-SScer\UAS.cVa in vitro construct - regulatory fusion 0 -- maf-SScer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6070 (Ryder, 2004.4.26) Df(2R)Exel7164 (Ryder, 2004.4.26) Df(2R)exu2 (Veraksa et al., 2000)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4373} NA P{KK102044} NA P{TRiP.HMS02020} NA P{TRiP.JF02008} NA P{UAS-maf-S.V} NA P{UAS-maf-S-HA} NA characterization construct PBac{maf-S-GFP.FPTB} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function
CV term Evidence References
protein heterodimerization activity inferred from physical interaction with cnc (Veraksa et al., 2000) contributes_to sequence-specific DNA binding transcription factor activity inferred from direct assay (Veraksa et al., 2000)
Biological Process
CV term Evidence References
autophagic cell death inferred from expression pattern (Gorski et al., 2003) head development inferred from mutant phenotype (Veraksa et al., 2000) positive regulation of transcription from RNA polymerase II promoter inferred from direct assay (Veraksa et al., 2000) salivary gland cell autophagic cell death inferred from expression pattern (Gorski et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
protein heterodimerization activity inferred from sequence or structural similarity (Fassler et al., 2002) protein homodimerization activity inferred from sequence or structural similarity (Fassler et al., 2002) sequence-specific DNA binding inferred from electronic annotation with InterPro:IPR004827 (FlyBase Curators et al., 2004-) sequence-specific DNA binding transcription factor activity inferred from sequence or structural similarity with UniProtKB:Q90596 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transcription, DNA-dependent inferred from sequence or structural similarity with UniProtKB:Q90596 (FlyBase, 1992-) transcription from RNA polymerase II promoter non-traceable author statement (Mohler et al., 1997)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:Q90596 (FlyBase, 1992-) non-traceable author statement (Mohler et al., 1997)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions maf-S allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 62985 DroID - A comprehensive database of gene and protein interactions. • FBgn0034534 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37336
Orthologs
OrthoDB Orthologs (72) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QRHQN Dipteran inclusive ortholog search EOG6J6S19 Insect inclusive ortholog search EOG6189K1 Arthropod inclusive ortholog search EOG6QFTWW Metazoa inclusive ortholog search EOG65F8HJ
Orthologs in Drosophila Species (EOG6QRHQN)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\maf-S     Drosophila simulans   Dsim\GD11529     Drosophila simulans   Dsim\GD11528 Y   Drosophila sechellia   Dsec\GM22031 Y   Drosophila erecta   Dere\GG22047 Y   Drosophila yakuba   Dyak\maf-S Y   Drosophila ananassae   Dana\GF12187 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA22151 Y   Drosophila persimilis   Dper\GL17038 Y   Drosophila willistoni   Dwil\GK21710 Y   Drosophila virilis   Dvir\GJ17266 Y   Drosophila mojavensis   Dmoj\GI19689 Y   Drosophila grimshawi   Dgri\GH21986 Y
Orthologs in non-Drosophila Dipterans (EOG6J6S19)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011739   Anopheles gambiae Malaria mosquito  Agam\AGAP010405   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006161
Orthologs in non-Dipteran Insects (EOG6189K1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC726492   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008316   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH25117   Atta cephalotes Leafcutter ant  Acep\ACEP11559   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17473   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18813   Linepithema humile Argentine ant  Lhum\LH22513   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21533   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008795   Bombyx mori Silkmoth  Bmor\BGIBMGA000157   Pediculus humanus Human body louse  Phum\PHUM334270   Tribolium castaneum Red flour beetle  Tcas\TC015977
Orthologs in non-Insect Arthropods (EOG6QFTWW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_231203   Ixodes scapularis Deer tick  Isca\ISCW019222
Orthologs in non-Arthropod Metazoa (EOG65F8HJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Danio rerio Zebrafish  Drer\mafk   Danio rerio Zebrafish  Drer\ENSDARG00000076520   Danio rerio Zebrafish  Drer\maff   Danio rerio Zebrafish  Drer\maf   Danio rerio Zebrafish  Drer\mafg1   Danio rerio Zebrafish  Drer\mafb   Danio rerio Zebrafish  Drer\mafg2   Danio rerio Zebrafish  Drer\nrl   Danio rerio Zebrafish  Drer\mafl   Danio rerio Zebrafish  Drer\mafbb   Xenopus tropicalis Western clawed frog  Xtro\maff   Xenopus tropicalis Western clawed frog  Xtro\nrl   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000032746   Xenopus tropicalis Western clawed frog  Xtro\maf   Xenopus tropicalis Western clawed frog  Xtro\mafk   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000032364   Xenopus tropicalis Western clawed frog  Xtro\mafg   Gallus gallus Domestic chicken  Ggal\MAFF   Gallus gallus Domestic chicken  Ggal\MAFB   Gallus gallus Domestic chicken  Ggal\MAFK   Gallus gallus Domestic chicken  Ggal\MAFG   Mus musculus House mouse  Mmus\Mafa   Mus musculus House mouse  Mmus\Mafk   Mus musculus House mouse  Mmus\ENSMUSG00000055435   Mus musculus House mouse  Mmus\Mafb   Mus musculus House mouse  Mmus\Nrl   Mus musculus House mouse  Mmus\Mafg   Mus musculus House mouse  Mmus\Maff   Rattus norvegicus Norway rat  Rnor\Mafb   Rattus norvegicus Norway rat  Rnor\Mafk   Rattus norvegicus Norway rat  Rnor\Maf   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000036697   Rattus norvegicus Norway rat  Rnor\Maff   Rattus norvegicus Norway rat  Rnor\Nrl   Rattus norvegicus Norway rat  Rnor\Mafa   Homo sapiens Human  Hsap\MAFB   Homo sapiens Human  Hsap\MAFG   Homo sapiens Human  Hsap\ENSG00000178573   Homo sapiens Human  Hsap\NRL   Homo sapiens Human  Hsap\MAFK   Homo sapiens Human  Hsap\MAFA   Homo sapiens Human  Hsap\MAFF
Human Orthologs (7)
Gene OMIM HGNC Hsap\MAFB     Hsap\MAFG     Hsap\ENSG00000178573     Hsap\NRL     Hsap\MAFK     Hsap\MAFA     Hsap\MAFF
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11528 Drosophila sechellia Dsec\GM22031 Drosophila erecta Dere\GG22047 Drosophila yakuba Dyak\maf-S Drosophila ananassae Dana\GF12187 Drosophila pseudoobscura pseudoobscura Dpse\GA22151 Drosophila persimilis Dper\GL17038 Drosophila willistoni Dwil\GK21710 Drosophila virilis Dvir\GJ17266 Drosophila mojavensis Dmoj\GI19689 Drosophila grimshawi Dgri\GH21986
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	25986 y1 v1; P{TRiP.JF02008}attP2 40853 y1 v1; P{TRiP.HMS02020}attP40 42277 w1118; PBac{maf-S-GFP.FPTB}VK00033/TM3, Sb1
VDRC	v12711 w1118; P{GD4373}v12711/TM3 v12712 w1118; P{GD4373}v12712/TM3
Genomic Clones ( 2 )
	BACR08P05 BACR33D17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 23 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH02096
Other clones	AF171827 yak-em_maf
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH02196 GH14688 LP09958 LP17092 RH18236 RH18362 RH51354
Other clones	80387 EC13361 EC24426 EK213637 FGA001F08 FGC018G09 FGC030B12 FGH109B05 FGM103B12 FGM222C12 FGM224B08 FGM237C03 FGM316D08
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034534 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37336
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: maf-S CG9954 (Veraksa et al., 2000)
Source for database merge of	Source for merge of: CG9954 anon-EST:Posey173 (Bayraktaroglu, 2000.11.2) Source for merge of: maf-S maf2 (Mohler, 2006.5.4)
Additional comments
Other Comments
	Isolated in a yeast two-hybrid screen for proteins interacting with cnc. (Mohler et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137656 RefSeq (Proteins) • NP_611500 DDBJ / EMBL / GenBank • AAF57439 AF171827 AI062774 Entrez Gene - A searchable database of RefSeq genes. • 37336 UniProtKB/TrEMBL • Q4QPP9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Basic leucine zipper domain, Maf-type (IPR004826) Basic-leucine zipper domain (IPR004827) Eukaryotic transcription factor, Skn-1-like, DNA-binding (IPR008917) Transcription factor Maf (IPR024874) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH02096
Linkouts
	BioGRID - A database of protein and genetic interactions • 62985 DroID - A comprehensive database of gene and protein interactions. • FBgn0034534 DRSC - Results from RNAi screens. • FBgn0034534 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034534 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9954-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034534 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37336 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37336 modMine - Data generated by the modENCODE project. • FBgn0034534
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	anon-EST:Posey173   CG9954 (Fassler et al., 2002, Perkins et al., 1.15.2009, Keleman et al., 2009.8.5, Barone et al., 2011, Ni et al., 2010.12.1) maf2 (Vani et al., 1997, Mohler et al., 1997, ) maf-S (Grimberg et al., 2011, Mourikis et al., 2010, Abruzzi et al., 2011, Spokony and White, 2012.11.14) Maf-S (Barone et al., 2011, Spresser et al., 2008)
Name Synonym	maf-S
Secondary FlyBase IDs
	FBgn0020275 FBgn0027740
References ( 31 )
Generate a list of	All references relating to this gene ( 31 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 4 )
	Chatterjee and Bohmann, 2012, PLoS ONE 7(4): e34063 A Versatile ΦC31 Based Reporter System for Measuring AP-1 and Nrf2 Signaling in Drosophila and in Tissue Culture. [FBrf0218067] Abruzzi et al., 2011, Genes Dev. 25(22): 2374--2386 Drosophila CLOCK target gene characterization: implications for circadian tissue-specific gene expression. [FBrf0216798] Barone et al., 2011, Dis. Model Mech. 4(5): 701--707 Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. [FBrf0215025] Grimberg et al., 2011, Mol. Cell. Biol. 31(4): 897--909 Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome. [FBrf0212906] Show all research papers ...