Please see the JBrowse view of Dmel\dgt3 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Component of the augmin complex composed of dgt2, dgt3, dgt4, dgt5, dgt6, msd1, msd5 and wac (PubMed:18443220, PubMed:19369198). The complex interacts directly or indirectly with microtubules and is required for centrosome-independent generation of spindle microtubules (PubMed:18443220).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dgt3 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\dgt3 in JBrowse2-92
2-99.5
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the failure of γ-tubulin to localize to the spindle, without affecting its localization to the pole, and the formation of an aberrantly long spindle when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the production of long spindles with low microtubule density, misaligned chromosomes/kinetochores and mitotic delay when assayed in S2 cells.
Named "dim γ-tubulin 3" for the decreased γ-tubulin staining of the spindle pole following treatment of S2 cells with dgt3 dsRNA.
