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Gene Dmel\mRpL54

General Information
Symbol	Dmel\mRpL54	Species	D. melanogaster
Name	mitochondrial ribosomal protein L54	Annotation symbol	CG9353
Feature type	protein_coding_gene	FlyBase ID	FBgn0034579
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	57B16-57B16	Sequence location	2R:16,948,294..16,949,092 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mitochondrial ribosomal protein L54 is referred to in FlyBase by the symbol Dmel\mRpL54 (CG9353, FBgn0034579). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. It is reported to be involved in the biological process: mitochondrial translation. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein L37, mitochondrial. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult salivary gland, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1624228_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mRpL54. Gene sequence location is 2R:16948284..16949092.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 57B16-57B16   Limits computationally determined from genome sequence between P{EP}grauEP688&P{PZ}shg10469 and P{PZ}king-tubby02821&P{lacW}Xbp1k13803
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mRpL54 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mRpL54-RA FBtr0071533  NM_137697   682   132
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mRpL54-PA   FBpp0071462   15.1   132   10.65     NP_611541   AAF46662
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L37, mitochondrial (IPR013870)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF46662   AI542704   AW944581   AY069845 AAL39990   BP546073   BT044303   CO297454   EC084383   EC090059   EC236414   EC255461   FL502712
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W2M8 Q8T9B2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult salivary gland, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    162.15 Larval Midgut    57.4 Larval Hindgut    136.9 Larval Malpighian Tubules    57.6 Larval Fat Body    45.9 Larval Salivary Gland    112.4 Larval Trachea    86.875 Larval Carcass    92.375 Adult Head    84.9 Adult Eye    81.2 Adult Brain    136.3 Adult Thoracic-Abdominal Ganglion    139.5 Adult Crop    100.1 Adult Midgut    79.3 Adult Hindgut    167.3 Adult Malpighian Tubules    85.6 Adult Fat Body    74.7 Adult Salivary Gland    159.2 Adult Heart    93.05 Adult VirginFemale Spermatheca    58.3 Adult InseminatedFemale Spermatheca    77.3 Adult Ovary    263.2 Adult Testis    28.8 Adult Male Accessory Gland    125.5 Adult Carcass    92.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    84.9   NA  Eye    81.2   NA  Brain    136.3   162.15  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    139.5   NA  Crop    100.1   57.4  Midgut    79.3   136.9  Hindgut    167.3   57.6  Malpighian Tubules    85.6   45.9  Fat Body    74.7   112.4  Salivary Gland    159.2   NA  Heart    93.05   86.875  Trachea    NA   NA  VirginFemale Spermatheca    58.3   NA  InseminatedFemale Spermatheca    77.3   NA  Ovary    263.2   NA  Testis    28.8   NA  Male Accessory Gland    125.5   92.375  Carcass    92.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female  (31) ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female  31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    11 central nervous system, larvae L3    10 central nervous system, pupae P8    7 head, virgin 1-day female    11 head, virgin 4-day female    6 head, virgin 20-day female    4 head, mated 1-day female    7 head, mated 4-day female    6 head, mated 20-day female    5 head, mated 1-day male    9 head, mated 4-day male    8 head, mated 20-day male    13 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    11 digestive system, 4-day adult    8 digestive system, 20-day adult    6 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    8 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    9 ovary, virgin 4-day female    31 ovary, mated 4-day female    22 testis, mated 4-day male    9 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr  (32) embryo 12-14hr  (28) embryo 14-16hr    25 embryo 16-18hr  (35) embryo 18-20hr  (31) embryo 20-22hr  (28) embryo 22-24hr  (29) larva L1  (31) larva L2  (41) larva L3 12hr old  (28) larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP  (35) pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day  (30) adult female 30day  (28) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr  32 embryo 12-14hr  28 embryo 14-16hr    25 embryo 16-18hr  (35) embryo 18-20hr  31 embryo 20-22hr  28 embryo 22-24hr  29 larva L1  31 larva L2  (41) larva L3 12hr old  28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP  (35) pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day  30 adult female 30day  28 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    24 embryo 02-04hr    8 embryo 04-06hr    13 embryo 06-08hr    16 embryo 08-10hr    18 embryo 10-12hr    32 embryo 12-14hr    28 embryo 14-16hr    25 embryo 16-18hr    35 embryo 18-20hr    31 embryo 20-22hr    28 embryo 22-24hr    29 larva L1    31 larva L2    41 larva L3 12hr old    28 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    10 white prepupae new    10 white prepupae 12hr    9 white prepupae 24hr    11 pupae 2d postWPP    23 pupae 3d postWPP    35 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    13 adult male 30day    11 adult female 01day    17 adult female 05day    30 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (27) Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1  (29) embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21  (35) wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1  29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21  (35) wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    19 embryonic 1182-4H    15 embryonic GM2    11 embryonic Kc167    6 embryonic S1    29 embryonic S3    23 leg disc CME L1    17 wing disc CME-W2    21 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    35 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    17 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    11 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    15 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    5 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_09 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034579 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9353-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 mRpL54GD12550 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 mRpL54GD12550 visible, with Scer\GAL4pnr-MD237 mRpL54GD12550 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 mRpL54GD12550 trichogen cell, with Scer\GAL4pnr-MD237 mRpL54GD12550
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of mRpL54 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mRpL54 Class Mutagen Stocks Known lesion mRpL54GD12550 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mRpL54GL01565 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mRpL54KK107920 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6072 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12550} NA P{KK107920} NA P{TRiP.GL01565} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with Saccharomyces MRPL37 (Curators, 2008--)
Biological Process
CV term Evidence References
mitochondrial translation inferred by curator from GO:0005762 (Curators, 2008--)
Cellular Component
CV term Evidence References
mitochondrial large ribosomal subunit inferred from sequence or structural similarity with Saccharomyces MRPL37 (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
mRpL54 - AR-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG15345 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG4278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG4300 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG5660 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG6227 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG6852 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG7339 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG7686 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CG8005 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - CrebA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - GstD10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - HIP-R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - Sbp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - bap anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - fan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL54 - ihog anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mRpL54 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63028 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034579 DroID - A comprehensive database of gene and protein interactions. • FBgn0034579 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37389
Orthologs
OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69KGB8 Dipteran inclusive ortholog search EOG6G1MRZ Insect inclusive ortholog search EOG69ZWM4 Arthropod inclusive ortholog search EOG6PNW0R Metazoa inclusive ortholog search EOG6DG2J4
Orthologs in Drosophila Species (EOG69KGB8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\mRpL54     Drosophila sechellia   Dsec\GM15799 Y   Drosophila erecta   Dere\GG22080 Y   Drosophila yakuba   Dyak\GE12161 Y   Drosophila ananassae   Dana\GF11928 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21722 Y   Drosophila persimilis   Dper\GL10146 Y   Drosophila willistoni   Dwil\GK23267 Y   Drosophila virilis   Dvir\GJ22436 Y   Drosophila mojavensis   Dmoj\GI18974 Y   Drosophila grimshawi   Dgri\GH20528 Y   Drosophila grimshawi   Dgri\GH12746
Orthologs in non-Drosophila Dipterans (EOG6G1MRZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013771   Anopheles gambiae Malaria mosquito  Agam\AGAP006916   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011273
Orthologs in non-Dipteran Insects (EOG69ZWM4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46748   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17344   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14635   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20201   Linepithema humile Argentine ant  Lhum\LH20999   Pogonomyrmex barbatus Red harvester ant  Pbar\PB24631   Solenopsis invicta Red fire ant  Sinv\SINV13197   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001324   Bombyx mori Silkmoth  Bmor\BGIBMGA013884   Tribolium castaneum Red flour beetle  Tcas\TC001025
Orthologs in non-Insect Arthropods (EOG6PNW0R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_49671   Ixodes scapularis Deer tick  Isca\ISCW010638
Orthologs in non-Arthropod Metazoa (EOG6DG2J4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\mrpl-54   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016635gn   Danio rerio Zebrafish  Drer\mrpl54   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033250   Mus musculus House mouse  Mmus\Mrpl54   Rattus norvegicus Norway rat  Rnor\Mrpl54   Homo sapiens Human  Hsap\MRPL54
Human Orthologs (1)
Gene OMIM HGNC Hsap\MRPL54
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11559 Drosophila sechellia Dsec\GM15799 Drosophila erecta Dere\GG22080 Drosophila yakuba Dyak\GE12161 Drosophila ananassae Dana\GF11928 Drosophila pseudoobscura pseudoobscura Dpse\GA21722 Drosophila persimilis Dper\GL10146 Drosophila willistoni Dwil\GK23267 Drosophila virilis Dvir\GJ22436 Drosophila mojavensis Dmoj\GI18974 Drosophila grimshawi Dgri\GH20528
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	43220 y1 sc* v1; P{TRiP.GL01565}attP40
VDRC	v105729 P{KK107920}VIE-260B v35447 w1118; P{GD12550}v35447
Genomic Clones ( 1 )
	BACR16B07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD09147
Other clones	DPiM_FI06587 FI06587
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	33970 83372 179712 214309.65 DMG4-chr2R.29.009.pred.a EK217020 FGH102E09
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034579 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37389
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: mRpL54 BcDNA:SD09147 (FlyBase, 1996-)
Additional comments	Source for merge of mRpL54 BcDNA:SD09147 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137697 RefSeq (Proteins) • NP_611541 DDBJ / EMBL / GenBank • AAF46662 AAL39990 AI542704 AW944581 AY069845 Entrez Gene - A searchable database of RefSeq genes. • 37389 UniProtKB/TrEMBL • Q8T9B2 Q9W2M8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L37, mitochondrial (IPR013870)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63028 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034579 DroID - A comprehensive database of gene and protein interactions. • FBgn0034579 DRSC - Results from RNAi screens. • FBgn0034579 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034579 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9353-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034579 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37389 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37389 modMine - Data generated by the modENCODE project. • FBgn0034579
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	BcDNA:SD09147   CG9353 (Keleman et al., 2009.8.5, Marygold et al., 2007, Ni et al., 2010.12.1) MRP-L54 (Koc et al., 2001) mRpL54 (Herranz et al., 2010, Marygold et al., 2007)
Name Synonym	mitochondrial ribosomal protein L54 (Koc et al., 2001)
Secondary FlyBase IDs
	FBgn0046987
References ( 16 )
Research paper	Herranz et al., 2010, Mol. Ecol. 19(19): 4255--4264 Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. [FBrf0216346] Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Szuperak et al., 2005, Gene Expr. Patterns 5(5): 717--723 Identification of germ plasm-enriched mRNAs in Drosophila melanogaster by the cDNA microarray technique. [FBrf0187585] Koc et al., 2001, J. Biol. Chem. 276(47): 43958--43969 The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. [FBrf0145610]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	Curators, 2008--, Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. [FBrf0202953] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]