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Gene Dmel\CG10433

General Information
Symbol	Dmel\CG10433	Species	D. melanogaster
Name		Annotation symbol	CG10433
Feature type	protein_coding_gene	FlyBase ID	FBgn0034638
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	57F3-57F3	Sequence location	2R:17,493,181..17,494,462 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10433 (FBgn0034638). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: multicellular organism reproduction. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult heart, larval/adult fat body, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, adult Malpighian tubules, adult salivary gland, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1627489_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG10433. Gene sequence location is 2R:17493181..17494458.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 57F3-57F3   Limits computationally determined from genome sequence between P{PZ}Egfr05351 and P{EP}CG10082EP436&P{EP}EP712EP712
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10433 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10433-RA FBtr0071690  NM_137746   945   127 CG10433-RB FBtr0071691  NM_166463   1112   98
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10433-PA   FBpp0071607   13.9   127   5.59     NP_611590   AAF46736 CG10433-PB   FBpp0071608   10.7   98   4.97     NP_726088   AAM70922
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567106   AE013599 AAF46736   AE013599 AAM70922   AI063698   AI109456   AI109751   AI113964   AI135744   AI135769   AI387230   AI405680   AI405844   AI513805   AI513977   AI517824   AW940366   AY094699 AAM11052   BG632342   BG639289   BI171492   BI171494   BI213754   BI232061   BI357357   BI357656   BI367114   BI370353   BI371238   BI565449   BI568421   BI571497   BI571748   BI571791   BI591176   BI593456   BI609052   BI610737   BI616540   BT120316   CA803698   CA804175   CA804219   CA804542   CA806147   CA806266   CA806488   CA807123   CK131243   CO188506   CO267176   CO269968   CO270310   CO280090   CO285561   CO287770   CO288951   CO296834   CO299241   CO300081   CO323066   CO326799   CO327216   CO327889   CO330591   CO332951   CO333348   DN154530   EC059059   EC061468   EC066280   EC067498   EC070992   EC071246   EC071908   EC079384   EC080661   EC087226   EC207962   EC211596   EC217042   EC219269   EC222666   EC231477   EC231883   EC231918   EC234587   EC235325   EC236070   EC236298   EC239814   EC245143   EC245226   EC252857   EC254488   EC255350   EV576414   EV599503   GH941714   GH942100   GH944439   GH945098   GH945771   GH947336   GH947514   GH948551   GH950952   GH951230   GH958852   GH960917   GH965586   GH967221   GH971265   GH972139   GH972405   GH973628   GH975212   GH975691   GH978997   GH979062   GH979196   GH980846   GH981016   GH981571
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SXB9 Q9W2F6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 9 -- 10   amnioserosa   (Fisher et al., 2012) embryonic stage 11 -- 12   amnioserosa   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic proventriculus   (Fisher et al., 2012) embryonic/larval salivary gland   (Fisher et al., 2012) embryonic/larval salivary gland body   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular space inferred from direct assay (Findlay et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult heart, larval/adult fat body, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, adult Malpighian tubules, adult salivary gland, larval trachea. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head    2527.7 Adult Eye    2414.975 Adult Brain    2736.5 Adult Thoracic-Abdominal Ganglion    4043.6 Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body    4736.2 Adult Salivary Gland    258.6 Adult Heart    5805.15 Adult VirginFemale Spermatheca    4349.6 Adult InseminatedFemale Spermatheca    4012.7 Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland    1482.6 Adult Carcass    4259.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut  505.6 Larval Malpighian Tubules    85.6 Larval Fat Body  (777.6) Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass  (701.9) Adult Head  (2527.7) Adult Eye  (2414.975) Adult Brain  (2736.5) Adult Thoracic-Abdominal Ganglion  (4043.6) Adult Crop  (997.4) Adult Midgut    218 Adult Hindgut  504.9 Adult Malpighian Tubules    138.1 Adult Fat Body  (4736.2) Adult Salivary Gland    258.6 Adult Heart  (5805.15) Adult VirginFemale Spermatheca  (4349.6) Adult InseminatedFemale Spermatheca  (4012.7) Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland  (1482.6) Adult Carcass  (4259.6) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head  (2527.7) Adult Eye  (2414.975) Adult Brain  (2736.5) Adult Thoracic-Abdominal Ganglion  (4043.6) Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body  (4736.2) Adult Salivary Gland    258.6 Adult Heart  (5805.15) Adult VirginFemale Spermatheca  (4349.6) Adult InseminatedFemale Spermatheca  (4012.7) Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland  (1482.6) Adult Carcass  (4259.6) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head    2527.7 Adult Eye    2414.975 Adult Brain    2736.5 Adult Thoracic-Abdominal Ganglion    4043.6 Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body    4736.2 Adult Salivary Gland    258.6 Adult Heart    5805.15 Adult VirginFemale Spermatheca    4349.6 Adult InseminatedFemale Spermatheca    4012.7 Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland    1482.6 Adult Carcass    4259.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head    2527.7 Adult Eye    2414.975 Adult Brain    2736.5 Adult Thoracic-Abdominal Ganglion    4043.6 Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body    4736.2 Adult Salivary Gland    258.6 Adult Heart    5805.15 Adult VirginFemale Spermatheca    4349.6 Adult InseminatedFemale Spermatheca    4012.7 Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland    1482.6 Adult Carcass    4259.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut  505.6 Larval Malpighian Tubules    85.6 Larval Fat Body  777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass  701.9 Adult Head  (2527.7) Adult Eye  (2414.975) Adult Brain  (2736.5) Adult Thoracic-Abdominal Ganglion  (4043.6) Adult Crop  (997.4) Adult Midgut    218 Adult Hindgut  504.9 Adult Malpighian Tubules    138.1 Adult Fat Body  (4736.2) Adult Salivary Gland    258.6 Adult Heart  (5805.15) Adult VirginFemale Spermatheca  (4349.6) Adult InseminatedFemale Spermatheca  (4012.7) Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland  (1482.6) Adult Carcass  (4259.6) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head  (2527.7) Adult Eye  (2414.975) Adult Brain  (2736.5) Adult Thoracic-Abdominal Ganglion  (4043.6) Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body  (4736.2) Adult Salivary Gland    258.6 Adult Heart  (5805.15) Adult VirginFemale Spermatheca  (4349.6) Adult InseminatedFemale Spermatheca  (4012.7) Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland  1482.6 Adult Carcass  (4259.6) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    315.95 Larval Midgut    198.3 Larval Hindgut    505.6 Larval Malpighian Tubules    85.6 Larval Fat Body    777.6 Larval Salivary Gland    78.1 Larval Trachea    180 Larval Carcass    701.9 Adult Head    2527.7 Adult Eye    2414.975 Adult Brain    2736.5 Adult Thoracic-Abdominal Ganglion    4043.6 Adult Crop    997.4 Adult Midgut    218 Adult Hindgut    504.9 Adult Malpighian Tubules    138.1 Adult Fat Body    4736.2 Adult Salivary Gland    258.6 Adult Heart    5805.15 Adult VirginFemale Spermatheca    4349.6 Adult InseminatedFemale Spermatheca    4012.7 Adult Ovary    72 Adult Testis    59.5 Adult Male Accessory Gland    1482.6 Adult Carcass    4259.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2527.7   NA  Eye    2414.975   NA  Brain    2736.5   315.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4043.6   NA  Crop    997.4   198.3  Midgut    218   505.6  Hindgut    504.9   85.6  Malpighian Tubules    138.1   777.6  Fat Body    4736.2   no informative data  Salivary Gland    258.6   NA  Heart    5805.15   180  Trachea    NA   NA  VirginFemale Spermatheca    4349.6   NA  InseminatedFemale Spermatheca    4012.7   NA  Ovary    72   NA  Testis    59.5   NA  Male Accessory Gland    1482.6   701.9  Carcass    4259.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female    131 head, virgin 4-day female    360 head, virgin 20-day female    497 head, mated 1-day female    209 head, mated 4-day female    313 head, mated 20-day female    439 head, mated 1-day male    278 head, mated 4-day male    395 head, mated 20-day male    740 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult    168 carcass, 4-day adult    259 carcass, 20-day adult    491 ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female  (131) head, virgin 4-day female  (360) head, virgin 20-day female  (497) head, mated 1-day female  (209) head, mated 4-day female  (313) head, mated 20-day female  (439) head, mated 1-day male  (278) head, mated 4-day male  (395) head, mated 20-day male  (740) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering  (74) fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult  (168) carcass, 4-day adult  (259) carcass, 20-day adult  (491) ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female  (131) head, virgin 4-day female  (360) head, virgin 20-day female  (497) head, mated 1-day female  (209) head, mated 4-day female  (313) head, mated 20-day female  (439) head, mated 1-day male  (278) head, mated 4-day male  (395) head, mated 20-day male  (740) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult  (168) carcass, 4-day adult  (259) carcass, 20-day adult  (491) ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female    131 head, virgin 4-day female    360 head, virgin 20-day female    497 head, mated 1-day female    209 head, mated 4-day female    313 head, mated 20-day female    439 head, mated 1-day male    278 head, mated 4-day male    395 head, mated 20-day male    740 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult    168 carcass, 4-day adult    259 carcass, 20-day adult    491 ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female    131 head, virgin 4-day female    360 head, virgin 20-day female    497 head, mated 1-day female    209 head, mated 4-day female    313 head, mated 20-day female    439 head, mated 1-day male    278 head, mated 4-day male    395 head, mated 20-day male    740 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult    168 carcass, 4-day adult    259 carcass, 20-day adult    491 ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female  (131) head, virgin 4-day female  (360) head, virgin 20-day female  (497) head, mated 1-day female  (209) head, mated 4-day female  (313) head, mated 20-day female  (439) head, mated 1-day male  (278) head, mated 4-day male  (395) head, mated 20-day male  (740) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering  (74) fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult  (168) carcass, 4-day adult  (259) carcass, 20-day adult  (491) ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female  131 head, virgin 4-day female  (360) head, virgin 20-day female  (497) head, mated 1-day female  (209) head, mated 4-day female  (313) head, mated 20-day female  (439) head, mated 1-day male  (278) head, mated 4-day male  (395) head, mated 20-day male  (740) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult  (168) carcass, 4-day adult  (259) carcass, 20-day adult  (491) ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    13 central nervous system, pupae P8    5 head, virgin 1-day female    131 head, virgin 4-day female    360 head, virgin 20-day female    497 head, mated 1-day female    209 head, mated 4-day female    313 head, mated 20-day female    439 head, mated 1-day male    278 head, mated 4-day male    395 head, mated 20-day male    740 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    18 digestive system, 4-day adult    17 digestive system, 20-day adult    19 fat body, larvae L3 wandering    74 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    14 carcass, 1-day adult    168 carcass, 4-day adult    259 carcass, 20-day adult    491 ovary, virgin 4-day female    3 ovary, mated 4-day female    3 testis, mated 4-day male    10 accessory gland, mated 4-day male    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr    145 embryo 20-22hr    243 embryo 22-24hr    237 larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP    198 adult male 01day    138 adult male 05day    223 adult male 30day    300 adult female 01day    109 adult female 05day    62 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr  (46) embryo 18-20hr  (145) embryo 20-22hr  (243) embryo 22-24hr  (237) larva L1  (77) larva L2  (31) larva L3 12hr old  (60) larva L3 puffstage 1-2  (69) larva L3 puffstage 3-6  (32) larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr  (86) white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP  (198) adult male 01day  (138) adult male 05day  (223) adult male 30day  (300) adult female 01day  (109) adult female 05day  (62) adult female 30day  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr  (145) embryo 20-22hr  (243) embryo 22-24hr  (237) larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP  (198) adult male 01day  (138) adult male 05day  (223) adult male 30day  (300) adult female 01day  (109) adult female 05day    62 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr    145 embryo 20-22hr    243 embryo 22-24hr    237 larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP    198 adult male 01day    138 adult male 05day    223 adult male 30day    300 adult female 01day    109 adult female 05day    62 adult female 30day    93 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr    145 embryo 20-22hr    243 embryo 22-24hr    237 larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP    198 adult male 01day    138 adult male 05day    223 adult male 30day    300 adult female 01day    109 adult female 05day    62 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr  (46) embryo 18-20hr  (145) embryo 20-22hr  (243) embryo 22-24hr  (237) larva L1  (77) larva L2  31 larva L3 12hr old  (60) larva L3 puffstage 1-2  (69) larva L3 puffstage 3-6  32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr  (86) white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP  (198) adult male 01day  (138) adult male 05day  (223) adult male 30day  (300) adult female 01day  (109) adult female 05day  (62) adult female 30day  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr  (145) embryo 20-22hr  (243) embryo 22-24hr  (237) larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP  (198) adult male 01day  138 adult male 05day  (223) adult male 30day  (300) adult female 01day  109 adult female 05day    62 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    5 embryo 10-12hr    9 embryo 12-14hr    7 embryo 14-16hr    22 embryo 16-18hr    46 embryo 18-20hr    145 embryo 20-22hr    243 embryo 22-24hr    237 larva L1    77 larva L2    31 larva L3 12hr old    60 larva L3 puffstage 1-2    69 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    19 white prepupae new    10 white prepupae 12hr    86 white prepupae 24hr    11 pupae 2d postWPP    18 pupae 3d postWPP    19 pupae 4d postWPP    198 adult male 01day    138 adult male 05day    223 adult male 30day    300 adult female 01day    109 adult female 05day    62 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167  (51) embryonic S1  (93) embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1  (27) CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167  (51) embryonic S1  (93) embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1  27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    3 embryonic 1182-4H    6 embryonic GM2    14 embryonic Kc167    51 embryonic S1    93 embryonic S3    1 leg disc CME L1    3 wing disc CME-W2    3 wing disc ML-DmD8    2 wing disc ML-DmD9    4 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    6 tumorous blood cells mbn2    2 ovary fGS/OSS    2 ovary OSC    0 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    234 Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    156 Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult    151 Paraquat 10 mM 48 hrs, 4-day adult    115 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (55) cold shock, 4-day adult  (38) heat shock, 4-day adult  (56) Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult  (50) Cadmium 100 mM 48 hrs, 4-day adult  (93) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  (234) Ethanol 2.5% 3 hrs, larvae L3  (90) Ethanol 5% 3 hrs, larvae L3  (77) Ethanol 10% 3 hrs, larvae L3  (32) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (74) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (156) Caffeine 25 mg/ml 48 hrs, 4-day adult  (47) Paraquat 5 mM 48 hrs, 4-day adult  (151) Paraquat 10 mM 48 hrs, 4-day adult  (115) Rotenone 2 μg 12 hrs, larvae L3  (30) Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  (234) Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (156) Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult  (151) Paraquat 10 mM 48 hrs, 4-day adult  (115) Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    234 Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    156 Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult    151 Paraquat 10 mM 48 hrs, 4-day adult    115 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    234 Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    156 Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult    151 Paraquat 10 mM 48 hrs, 4-day adult    115 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (55) cold shock, 4-day adult  (38) heat shock, 4-day adult  (56) Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult  (50) Cadmium 100 mM 48 hrs, 4-day adult  (93) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  (112) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  (234) Ethanol 2.5% 3 hrs, larvae L3  (90) Ethanol 5% 3 hrs, larvae L3  (77) Ethanol 10% 3 hrs, larvae L3  32 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (74) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (156) Caffeine 25 mg/ml 48 hrs, 4-day adult  (47) Paraquat 5 mM 48 hrs, 4-day adult  (151) Paraquat 10 mM 48 hrs, 4-day adult  (115) Rotenone 2 μg 12 hrs, larvae L3  30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  112 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  (234) Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (156) Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult  (151) Paraquat 10 mM 48 hrs, 4-day adult  115 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    55 cold shock, 4-day adult    38 heat shock, 4-day adult    56 Cadmium 50 mM 6 hrs, larvae L3    19 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    50 Cadmium 100 mM 48 hrs, 4-day adult    93 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    112 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    234 Ethanol 2.5% 3 hrs, larvae L3    90 Ethanol 5% 3 hrs, larvae L3    77 Ethanol 10% 3 hrs, larvae L3    32 Caffeine 1.5 mg/ml 4 hrs, larvae L3    74 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    156 Caffeine 25 mg/ml 48 hrs, 4-day adult    47 Paraquat 5 mM 48 hrs, 4-day adult    151 Paraquat 10 mM 48 hrs, 4-day adult    115 Rotenone 2 μg 12 hrs, larvae L3    30 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_10 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • GH10517 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034638 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10433-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4αTub84B.PL CG10433Scer\UAS.cMa viable, with Scer\GAL4pnr-MD237 CG10433GD4875 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG10433 Class Mutagen Stocks Known lesion CG10433EP2034 0 -- CG10433EP2516 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10433 Class Mutagen Stocks Known lesion CG10433GD4875 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10433Scer\UAS.cMa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6076 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4875} NA P{UAS-CG10433.M} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG10433EP2034 NA P{EP}CG10433EP2516 NA miscellaneous insertions P{SUPor-P}KG01543 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
	There is no information supporting a molecular function term for this gene. (Based on a review of available data on: 2012-11-15)
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
multicellular organism reproduction inferred from expression pattern (Findlay et al., 2008, Mueller et al., 2005)
Cellular Component
CV term Evidence References
extracellular space inferred from direct assay (Findlay et al., 2008)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
defense response inferred from sequence or structural similarity (Mueller et al., 2004)
Cellular Component
CV term Evidence References
extracellular space inferred from sequence model (Mueller et al., 2005)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10433 allele Gene References CG10433EP2034 btl (Zhu et al., 2005) Pvr (Zhu et al., 2005) CG10433EP2516 btl (Zhu et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63085 DroID - A comprehensive database of gene and protein interactions. • FBgn0034638 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37458
Orthologs
OrthoDB Orthologs (18) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6JWW14 Dipteran inclusive ortholog search EOG6BP1N6 Insect inclusive ortholog search EOG6SJ4BG Arthropod inclusive ortholog search EOG65HQDX Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6JWW14)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG10433     Drosophila simulans   Dsim\GD25186 Y   Drosophila sechellia   Dsec\GM15708 Y   Drosophila erecta   Dere\GG20765 Y   Drosophila yakuba   Dyak\GE13697 Y   Drosophila ananassae   Dana\GF12088 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10315 Y   Drosophila persimilis   Dper\GL17485 Y   Drosophila willistoni   Dwil\GK22257 Y   Drosophila virilis   Dvir\GJ22309 Y   Drosophila mojavensis   Dmoj\GI20459 Y   Drosophila grimshawi   Dgri\GH20050 Y
Orthologs in non-Drosophila Dipterans (EOG6BP1N6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009861   Anopheles gambiae Malaria mosquito  Agam\AGAP007049   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004961
Orthologs in non-Dipteran Insects (EOG6SJ4BG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Pediculus humanus Human body louse  Phum\PHUM564690
Orthologs in non-Insect Arthropods (EOG65HQDX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\rpoC1   Ixodes scapularis Deer tick  Isca\ISCW003836
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25186 Drosophila sechellia Dsec\GM15708 Drosophila erecta Dere\GG20765 Drosophila yakuba Dyak\GE13697 Drosophila ananassae Dana\GF12088 Drosophila pseudoobscura pseudoobscura Dpse\GA10315 Drosophila persimilis Dper\GL17485 Drosophila willistoni Dwil\GK22257 Drosophila virilis Dvir\GJ22309 Drosophila mojavensis Dmoj\GI20459 Drosophila grimshawi Dgri\GH20050
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v41162 w1118; P{GD4875}v41162/TM3
Genomic Clones ( 2 )
	BACR34C17 BACR46G10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 118 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH10517 RE36793
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03654 GH06716 GH08665 GH09048 GH13606 GH13637 GH17692 GH25035 GH25782 GH25985 GH26904 GH27011 GH28888 GM01093 LP02537 RE13281 RE13283 RE19247 RE28067 RE43822 RE44186 RE52802 RE56842 RE58089 RH04905 RH06630 RH07033 RH07084 RH11514 RH13785 RH16419 RH39864 RH46517 RH63225
Other clones	9932 34164 39272 40539 50440 56721 58428 67192 78782 81351 81828 156041 192666 214275.69 214481.68 214569.53 280655 281814 CK01.50C.D6 CK01.88C.B2 CK01.97B.D5 CK01.100C.F1 CK01.110B.H1 CK01.113C.E4 CK01.126C.G1 CK01.132A.F9 CK01.133C.B4 Dmel_dig_018515_0673_1373 Dmel_neb_006702_0819_3283 EK040547 EK066725 EK069737 EK084921 EK097025 EK098505 EK148957 EK152435 EK169251 EK174902 EK177342 EK189609 EK215247 EK295643 EK305231 EK306548 EP04649 EP06460 EP08217 ESG012a.E21_G09 ESG012c.E21_D04 ESG013c.E21_E09 ESG016b.E21_F02 ESG0110a.E21_F10 ESG0112b.B21_G07 ESG0112c.B21.1_E11 ESG0114a.B21_E08 RP004020874 RP004159201 RP004166940 RP004198614 RP004208794 RP004210275 RP004227000 RP004230051 RP004235369 RP004236727 RP004237685 RP004241248 RP004253114 RP004255021 RP004255621 RP004259404 RP004262934 RP004337101 RP004348123 RP004378401 RP004398780 RP004402248 RP004414809 RP004470430 RP004491269 RP004540450
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034638 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37458
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Isolated in a screen for seminal fluid proteins. (Mueller et al., 2004) Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. (Claridge-Chang et al., 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137746 NM_166463 RefSeq (Proteins) • NP_611590 NP_726088 DDBJ / EMBL / GenBank • AAF46736 AAM11052 AAM70922 AI113964 AW940366 AY094699 Entrez Gene - A searchable database of RefSeq genes. • 37458 UniProtKB/TrEMBL • Q8SXB9 Q9W2F6
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH10517
Linkouts
	BioGRID - A database of protein and genetic interactions • 63085 DroID - A comprehensive database of gene and protein interactions. • FBgn0034638 DRSC - Results from RNAi screens. • FBgn0034638 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034638 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10433-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034638 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37458 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37458 modMine - Data generated by the modENCODE project. • FBgn0034638
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10433 (Ravi Ram and Wolfner, 2007, Mueller et al., 2007, Bartkuhn et al., 2009, Juhász et al., 2007, Ravi Ram and Wolfner, 2007)
Name Synonym
Secondary FlyBase IDs
References ( 28 )
Generate a list of	All references relating to this gene ( 28 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 7 ) Review  ( 1 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 1 ) Website  ( 1 )
Recent research papers ( 2 )
	Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Dottorini et al., 2011, BMC Bioinformatics 12: 34 Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. [FBrf0214379] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...