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Gene Dmel\CG2852

General Information
Symbol	Dmel\CG2852	Species	D. melanogaster
Name		Annotation symbol	CG2852
Feature type	protein_coding_gene	FlyBase ID	FBgn0034753
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	58F3-58F3	Sequence location	2R:18,532,446..18,533,849 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG2852 (FBgn0034753). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidyl-prolyl cis-trans isomerase activity. There is experimental evidence that it is involved in the biological process: multicellular organism reproduction. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1624611_a_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG2852. Gene sequence location is 2R:18532448..18533851.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 58F3-58F3   Limits computationally determined from genome sequence between P{PZ}l(2)rG270rG270 and P{EP}EP718EP718
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG2852 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39 Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG2852-RA FBtr0071933  NM_137851   882   205
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG2852-PA   FBpp0071844   22.2   205   9.37     NP_611695   AAF46873
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain (IPR002130) Cyclophilin-type peptidyl-prolyl cis-trans isomerase (IPR024936) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (IPR020892)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438824   AA696218   AA802046   AA803273   AA803700   AA950973   AA979414   AA979415   AE013599 AAF46873   AI063488   AI063685   AI109390   AI256898   AI257043   AI257926   AI257969   AI258845   AI260432   AI260670   AI261126   AI294710   AI295129   AI295835   AI296917   AI296920   AI388421   AI404984   AI517395   AY231875   AY232181   BF496389   BF500882   BG632849   BG641017   BI173454   BI212463   BI230748   BI239248   BI239986   BI240847   BI241255   BI352227   BI353380   BI353591   BI353791   BI355870   BI356135   BI357096   BI361739   BI363564   BI363949   BI365505   BI367595   BI367762   BI368568   BI369018   BI369234   BI369759   BI482278   BI563399   BI563692   BI574935   BI576739   BI586442   BI586482   BI586650   BI587184   BI592377   BI605648   BI605690   BI611122   BI618940   BI619155   BI619416   BI619954   BI621173   BI624484   BI634254   BI636274   BI636863   BI637896   BI640535   BP547839   BP548063   BP548868   BP549220   BP549412   BP549413   BP551007   BP551596   BP551650   BP552068   BP552835   BT021266 AAX33414   BT125794   BX010691   BX023394   BX025263   BX027425   BX032972   BX043544   BX045916   BX053494   BX059546   CA804598   CA807116   CA807299   CA807412   CK132174   CK604624   CK656945   CK657224   CK658001   CK661360   CK661831   CK662042   CO154415   CO155029   CO177763   CO182806   CO183270   CO184347   CO184530   CO190602   CO191815   CO268015   CO268514   CO272329   CO284418   CO286699   CO306377   CO309679   CO310333   CO331920   CO335528   CO337172   CR938040   CR938346   DQ440048   EC059539   EC066494   EC071813   EC090598   EC207090   EC213399   EC217356   EC229943   EC229944   EC231607   EC245085   EC263765   EC265639   EC266080   EC266764   EV575697   EV575955   EV578911   EV580129   EV581131   EV589065   EV589950   EV599049   GH942690   GH943238   GH943813   GH943854   GH944119   GH944303   GH944853   GH945331   GH945806   GH952012   GH955224   GH955804   GH957575   GH960565   GH960864   GH961156   GH961981   GH962127   GH962679   GH964148   GH965682   GH967784   GH967897   GH968186   GH968442   GH968670   GH971197   GH971765   GH973165   GH973220   GH973520   GH974087   GH974511   GH977357   GH977589   GH978002   GH978124   GH979848   GH979891   GH982455   GH983210   GH983274   GH983346   GH983467   GH983619
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W227
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004) extracellular space inferred from direct assay (Findlay et al., 2009, Walker et al., 2006, Findlay et al., 2008) lipid particle inferred from direct assay (Beller et al., 2006) microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2342 Larval Midgut    1293.9 Larval Hindgut    3947 Larval Malpighian Tubules    2074.2 Larval Fat Body    5080 Larval Salivary Gland    2066.7 Larval Trachea    3920.45 Larval Carcass    2710.775 Adult Head    2219.7 Adult Eye    1565.625 Adult Brain    2289 Adult Thoracic-Abdominal Ganglion    2835.9 Adult Crop    1349.1 Adult Midgut    1273.2 Adult Hindgut    2565.2 Adult Malpighian Tubules    1076.7 Adult Fat Body    2951 Adult Salivary Gland    1733.7 Adult Heart    2290.175 Adult VirginFemale Spermatheca    2738.4 Adult InseminatedFemale Spermatheca    2711.7 Adult Ovary    2471.4 Adult Testis    1127.6 Adult Male Accessory Gland    7626.8 Adult Carcass    2087.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2342) Larval Midgut  (1293.9) Larval Hindgut  (3947) Larval Malpighian Tubules  (2074.2) Larval Fat Body  (5080) Larval Salivary Gland  (2066.7) Larval Trachea  (3920.45) Larval Carcass  (2710.775) Adult Head  (2219.7) Adult Eye  (1565.625) Adult Brain  (2289) Adult Thoracic-Abdominal Ganglion  (2835.9) Adult Crop  (1349.1) Adult Midgut  (1273.2) Adult Hindgut  (2565.2) Adult Malpighian Tubules  (1076.7) Adult Fat Body  (2951) Adult Salivary Gland  (1733.7) Adult Heart  (2290.175) Adult VirginFemale Spermatheca  (2738.4) Adult InseminatedFemale Spermatheca  (2711.7) Adult Ovary  (2471.4) Adult Testis  (1127.6) Adult Male Accessory Gland  (7626.8) Adult Carcass  (2087.1) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2342) Larval Midgut  (1293.9) Larval Hindgut  (3947) Larval Malpighian Tubules  (2074.2) Larval Fat Body  (5080) Larval Salivary Gland  (2066.7) Larval Trachea  (3920.45) Larval Carcass  (2710.775) Adult Head  (2219.7) Adult Eye  (1565.625) Adult Brain  (2289) Adult Thoracic-Abdominal Ganglion  (2835.9) Adult Crop  (1349.1) Adult Midgut  (1273.2) Adult Hindgut  (2565.2) Adult Malpighian Tubules  1076.7 Adult Fat Body  (2951) Adult Salivary Gland  (1733.7) Adult Heart  (2290.175) Adult VirginFemale Spermatheca  (2738.4) Adult InseminatedFemale Spermatheca  (2711.7) Adult Ovary  (2471.4) Adult Testis  (1127.6) Adult Male Accessory Gland  (7626.8) Adult Carcass  (2087.1) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2342 Larval Midgut    1293.9 Larval Hindgut    3947 Larval Malpighian Tubules    2074.2 Larval Fat Body    5080 Larval Salivary Gland    2066.7 Larval Trachea    3920.45 Larval Carcass    2710.775 Adult Head    2219.7 Adult Eye    1565.625 Adult Brain    2289 Adult Thoracic-Abdominal Ganglion    2835.9 Adult Crop    1349.1 Adult Midgut    1273.2 Adult Hindgut    2565.2 Adult Malpighian Tubules    1076.7 Adult Fat Body    2951 Adult Salivary Gland    1733.7 Adult Heart    2290.175 Adult VirginFemale Spermatheca    2738.4 Adult InseminatedFemale Spermatheca    2711.7 Adult Ovary    2471.4 Adult Testis    1127.6 Adult Male Accessory Gland    7626.8 Adult Carcass    2087.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2342 Larval Midgut    1293.9 Larval Hindgut    3947 Larval Malpighian Tubules    2074.2 Larval Fat Body    5080 Larval Salivary Gland    2066.7 Larval Trachea    3920.45 Larval Carcass    2710.775 Adult Head    2219.7 Adult Eye    1565.625 Adult Brain    2289 Adult Thoracic-Abdominal Ganglion    2835.9 Adult Crop    1349.1 Adult Midgut    1273.2 Adult Hindgut    2565.2 Adult Malpighian Tubules    1076.7 Adult Fat Body    2951 Adult Salivary Gland    1733.7 Adult Heart    2290.175 Adult VirginFemale Spermatheca    2738.4 Adult InseminatedFemale Spermatheca    2711.7 Adult Ovary    2471.4 Adult Testis    1127.6 Adult Male Accessory Gland    7626.8 Adult Carcass    2087.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2342) Larval Midgut  (1293.9) Larval Hindgut  (3947) Larval Malpighian Tubules  (2074.2) Larval Fat Body  (5080) Larval Salivary Gland  (2066.7) Larval Trachea  (3920.45) Larval Carcass  (2710.775) Adult Head  (2219.7) Adult Eye  (1565.625) Adult Brain  (2289) Adult Thoracic-Abdominal Ganglion  (2835.9) Adult Crop  (1349.1) Adult Midgut  (1273.2) Adult Hindgut  (2565.2) Adult Malpighian Tubules  (1076.7) Adult Fat Body  (2951) Adult Salivary Gland  (1733.7) Adult Heart  (2290.175) Adult VirginFemale Spermatheca  (2738.4) Adult InseminatedFemale Spermatheca  (2711.7) Adult Ovary  (2471.4) Adult Testis  (1127.6) Adult Male Accessory Gland  (7626.8) Adult Carcass  (2087.1) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2342) Larval Midgut  1293.9 Larval Hindgut  (3947) Larval Malpighian Tubules  (2074.2) Larval Fat Body  (5080) Larval Salivary Gland  (2066.7) Larval Trachea  (3920.45) Larval Carcass  (2710.775) Adult Head  (2219.7) Adult Eye  1565.625 Adult Brain  (2289) Adult Thoracic-Abdominal Ganglion  (2835.9) Adult Crop  1349.1 Adult Midgut  1273.2 Adult Hindgut  (2565.2) Adult Malpighian Tubules  1076.7 Adult Fat Body  (2951) Adult Salivary Gland  (1733.7) Adult Heart  (2290.175) Adult VirginFemale Spermatheca  (2738.4) Adult InseminatedFemale Spermatheca  (2711.7) Adult Ovary  (2471.4) Adult Testis  1127.6 Adult Male Accessory Gland  (7626.8) Adult Carcass  (2087.1) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2342 Larval Midgut    1293.9 Larval Hindgut    3947 Larval Malpighian Tubules    2074.2 Larval Fat Body    5080 Larval Salivary Gland    2066.7 Larval Trachea    3920.45 Larval Carcass    2710.775 Adult Head    2219.7 Adult Eye    1565.625 Adult Brain    2289 Adult Thoracic-Abdominal Ganglion    2835.9 Adult Crop    1349.1 Adult Midgut    1273.2 Adult Hindgut    2565.2 Adult Malpighian Tubules    1076.7 Adult Fat Body    2951 Adult Salivary Gland    1733.7 Adult Heart    2290.175 Adult VirginFemale Spermatheca    2738.4 Adult InseminatedFemale Spermatheca    2711.7 Adult Ovary    2471.4 Adult Testis    1127.6 Adult Male Accessory Gland    7626.8 Adult Carcass    2087.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2219.7   NA  Eye    1565.625   NA  Brain    2289   2342  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2835.9   NA  Crop    1349.1   1293.9  Midgut    1273.2   3947  Hindgut    2565.2   2074.2  Malpighian Tubules    1076.7   5080  Fat Body    2951   2066.7  Salivary Gland    1733.7   NA  Heart    2290.175   3920.45  Trachea    NA   NA  VirginFemale Spermatheca    2738.4   NA  InseminatedFemale Spermatheca    2711.7   NA  Ovary    2471.4   NA  Testis    1127.6   NA  Male Accessory Gland    7626.8   2710.775  Carcass    2087.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    948 central nervous system, larvae L3    450 central nervous system, pupae P8    295 head, virgin 1-day female    152 head, virgin 4-day female    114 head, virgin 20-day female    196 head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female    162 head, mated 1-day male    130 head, mated 4-day male    125 head, mated 20-day male    194 salivary gland, larvae L3 wandering    133 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    390 digestive system, 1-day adult    149 digestive system, 4-day adult    97 digestive system, 20-day adult    122 fat body, larvae L3 wandering    362 fat body, white prepupae    238 fat body, pupae P8    570 carcass, larvae L3 wandering    530 carcass, 1-day adult    102 carcass, 4-day adult    102 carcass, 20-day adult    126 ovary, virgin 4-day female    403 ovary, mated 4-day female    336 testis, mated 4-day male    335 accessory gland, mated 4-day male    735 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (948) central nervous system, larvae L3  (450) central nervous system, pupae P8  (295) head, virgin 1-day female  (152) head, virgin 4-day female  (114) head, virgin 20-day female  (196) head, mated 1-day female  (97) head, mated 4-day female  (91) head, mated 20-day female  (162) head, mated 1-day male  (130) head, mated 4-day male  (125) head, mated 20-day male  (194) salivary gland, larvae L3 wandering  (133) salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (390) digestive system, 1-day adult  (149) digestive system, 4-day adult  (97) digestive system, 20-day adult  (122) fat body, larvae L3 wandering  (362) fat body, white prepupae  (238) fat body, pupae P8  (570) carcass, larvae L3 wandering  (530) carcass, 1-day adult  (102) carcass, 4-day adult  (102) carcass, 20-day adult  (126) ovary, virgin 4-day female  (403) ovary, mated 4-day female  (336) testis, mated 4-day male  (335) accessory gland, mated 4-day male  (735) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (948) central nervous system, larvae L3  (450) central nervous system, pupae P8  (295) head, virgin 1-day female  (152) head, virgin 4-day female  (114) head, virgin 20-day female  (196) head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female  (162) head, mated 1-day male  (130) head, mated 4-day male  (125) head, mated 20-day male  (194) salivary gland, larvae L3 wandering  (133) salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (390) digestive system, 1-day adult  (149) digestive system, 4-day adult    97 digestive system, 20-day adult  (122) fat body, larvae L3 wandering  (362) fat body, white prepupae  (238) fat body, pupae P8  (570) carcass, larvae L3 wandering  (530) carcass, 1-day adult  102 carcass, 4-day adult  102 carcass, 20-day adult  (126) ovary, virgin 4-day female  (403) ovary, mated 4-day female  (336) testis, mated 4-day male  (335) accessory gland, mated 4-day male  (735) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    948 central nervous system, larvae L3    450 central nervous system, pupae P8    295 head, virgin 1-day female    152 head, virgin 4-day female    114 head, virgin 20-day female    196 head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female    162 head, mated 1-day male    130 head, mated 4-day male    125 head, mated 20-day male    194 salivary gland, larvae L3 wandering    133 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    390 digestive system, 1-day adult    149 digestive system, 4-day adult    97 digestive system, 20-day adult    122 fat body, larvae L3 wandering    362 fat body, white prepupae    238 fat body, pupae P8    570 carcass, larvae L3 wandering    530 carcass, 1-day adult    102 carcass, 4-day adult    102 carcass, 20-day adult    126 ovary, virgin 4-day female    403 ovary, mated 4-day female    336 testis, mated 4-day male    335 accessory gland, mated 4-day male    735 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    948 central nervous system, larvae L3    450 central nervous system, pupae P8    295 head, virgin 1-day female    152 head, virgin 4-day female    114 head, virgin 20-day female    196 head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female    162 head, mated 1-day male    130 head, mated 4-day male    125 head, mated 20-day male    194 salivary gland, larvae L3 wandering    133 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    390 digestive system, 1-day adult    149 digestive system, 4-day adult    97 digestive system, 20-day adult    122 fat body, larvae L3 wandering    362 fat body, white prepupae    238 fat body, pupae P8    570 carcass, larvae L3 wandering    530 carcass, 1-day adult    102 carcass, 4-day adult    102 carcass, 20-day adult    126 ovary, virgin 4-day female    403 ovary, mated 4-day female    336 testis, mated 4-day male    335 accessory gland, mated 4-day male    735 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (948) central nervous system, larvae L3  (450) central nervous system, pupae P8  (295) head, virgin 1-day female  (152) head, virgin 4-day female  (114) head, virgin 20-day female  (196) head, mated 1-day female  (97) head, mated 4-day female  (91) head, mated 20-day female  (162) head, mated 1-day male  (130) head, mated 4-day male  (125) head, mated 20-day male  (194) salivary gland, larvae L3 wandering  (133) salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (390) digestive system, 1-day adult  (149) digestive system, 4-day adult  (97) digestive system, 20-day adult  (122) fat body, larvae L3 wandering  (362) fat body, white prepupae  (238) fat body, pupae P8  (570) carcass, larvae L3 wandering  (530) carcass, 1-day adult  (102) carcass, 4-day adult  (102) carcass, 20-day adult  (126) ovary, virgin 4-day female  (403) ovary, mated 4-day female  (336) testis, mated 4-day male  (335) accessory gland, mated 4-day male  (735) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (948) central nervous system, larvae L3  (450) central nervous system, pupae P8  (295) head, virgin 1-day female  (152) head, virgin 4-day female  114 head, virgin 20-day female  (196) head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female  (162) head, mated 1-day male  130 head, mated 4-day male  125 head, mated 20-day male  (194) salivary gland, larvae L3 wandering  133 salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (390) digestive system, 1-day adult  (149) digestive system, 4-day adult    97 digestive system, 20-day adult  122 fat body, larvae L3 wandering  (362) fat body, white prepupae  (238) fat body, pupae P8  (570) carcass, larvae L3 wandering  (530) carcass, 1-day adult  102 carcass, 4-day adult  102 carcass, 20-day adult  126 ovary, virgin 4-day female  (403) ovary, mated 4-day female  (336) testis, mated 4-day male  (335) accessory gland, mated 4-day male  (735) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    948 central nervous system, larvae L3    450 central nervous system, pupae P8    295 head, virgin 1-day female    152 head, virgin 4-day female    114 head, virgin 20-day female    196 head, mated 1-day female    97 head, mated 4-day female    91 head, mated 20-day female    162 head, mated 1-day male    130 head, mated 4-day male    125 head, mated 20-day male    194 salivary gland, larvae L3 wandering    133 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    390 digestive system, 1-day adult    149 digestive system, 4-day adult    97 digestive system, 20-day adult    122 fat body, larvae L3 wandering    362 fat body, white prepupae    238 fat body, pupae P8    570 carcass, larvae L3 wandering    530 carcass, 1-day adult    102 carcass, 4-day adult    102 carcass, 20-day adult    126 ovary, virgin 4-day female    403 ovary, mated 4-day female    336 testis, mated 4-day male    335 accessory gland, mated 4-day male    735 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    941 embryo 02-04hr    295 embryo 04-06hr    322 embryo 06-08hr    732 embryo 08-10hr    840 embryo 10-12hr    1584 embryo 12-14hr    828 embryo 14-16hr    769 embryo 16-18hr    445 embryo 18-20hr    310 embryo 20-22hr    176 embryo 22-24hr    158 larva L1    417 larva L2    992 larva L3 12hr old    669 larva L3 puffstage 1-2    588 larva L3 puffstage 3-6    815 larva L3 puffstage 7-9    1136 white prepupae new    1249 white prepupae 12hr    928 white prepupae 24hr    1585 pupae 2d postWPP    978 pupae 3d postWPP    289 pupae 4d postWPP    332 adult male 01day    321 adult male 05day    342 adult male 30day    372 adult female 01day    564 adult female 05day    764 adult female 30day    790 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (941) embryo 02-04hr  (295) embryo 04-06hr  (322) embryo 06-08hr  (732) embryo 08-10hr  (840) embryo 10-12hr  (1584) embryo 12-14hr  (828) embryo 14-16hr  (769) embryo 16-18hr  (445) embryo 18-20hr  (310) embryo 20-22hr  (176) embryo 22-24hr  (158) larva L1  (417) larva L2  (992) larva L3 12hr old  (669) larva L3 puffstage 1-2  (588) larva L3 puffstage 3-6  (815) larva L3 puffstage 7-9  (1136) white prepupae new  (1249) white prepupae 12hr  (928) white prepupae 24hr  (1585) pupae 2d postWPP  (978) pupae 3d postWPP  (289) pupae 4d postWPP  (332) adult male 01day  (321) adult male 05day  (342) adult male 30day  (372) adult female 01day  (564) adult female 05day  (764) adult female 30day  (790) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (941) embryo 02-04hr  (295) embryo 04-06hr  (322) embryo 06-08hr  (732) embryo 08-10hr  (840) embryo 10-12hr  (1584) embryo 12-14hr  (828) embryo 14-16hr  (769) embryo 16-18hr  (445) embryo 18-20hr  (310) embryo 20-22hr  (176) embryo 22-24hr  (158) larva L1  (417) larva L2  (992) larva L3 12hr old  (669) larva L3 puffstage 1-2  (588) larva L3 puffstage 3-6  (815) larva L3 puffstage 7-9  (1136) white prepupae new  (1249) white prepupae 12hr  (928) white prepupae 24hr  (1585) pupae 2d postWPP  (978) pupae 3d postWPP  (289) pupae 4d postWPP  (332) adult male 01day  (321) adult male 05day  (342) adult male 30day  (372) adult female 01day  (564) adult female 05day  (764) adult female 30day  (790) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    941 embryo 02-04hr    295 embryo 04-06hr    322 embryo 06-08hr    732 embryo 08-10hr    840 embryo 10-12hr    1584 embryo 12-14hr    828 embryo 14-16hr    769 embryo 16-18hr    445 embryo 18-20hr    310 embryo 20-22hr    176 embryo 22-24hr    158 larva L1    417 larva L2    992 larva L3 12hr old    669 larva L3 puffstage 1-2    588 larva L3 puffstage 3-6    815 larva L3 puffstage 7-9    1136 white prepupae new    1249 white prepupae 12hr    928 white prepupae 24hr    1585 pupae 2d postWPP    978 pupae 3d postWPP    289 pupae 4d postWPP    332 adult male 01day    321 adult male 05day    342 adult male 30day    372 adult female 01day    564 adult female 05day    764 adult female 30day    790 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    941 embryo 02-04hr    295 embryo 04-06hr    322 embryo 06-08hr    732 embryo 08-10hr    840 embryo 10-12hr    1584 embryo 12-14hr    828 embryo 14-16hr    769 embryo 16-18hr    445 embryo 18-20hr    310 embryo 20-22hr    176 embryo 22-24hr    158 larva L1    417 larva L2    992 larva L3 12hr old    669 larva L3 puffstage 1-2    588 larva L3 puffstage 3-6    815 larva L3 puffstage 7-9    1136 white prepupae new    1249 white prepupae 12hr    928 white prepupae 24hr    1585 pupae 2d postWPP    978 pupae 3d postWPP    289 pupae 4d postWPP    332 adult male 01day    321 adult male 05day    342 adult male 30day    372 adult female 01day    564 adult female 05day    764 adult female 30day    790 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (941) embryo 02-04hr  (295) embryo 04-06hr  (322) embryo 06-08hr  (732) embryo 08-10hr  (840) embryo 10-12hr  (1584) embryo 12-14hr  (828) embryo 14-16hr  (769) embryo 16-18hr  (445) embryo 18-20hr  (310) embryo 20-22hr  (176) embryo 22-24hr  (158) larva L1  (417) larva L2  (992) larva L3 12hr old  (669) larva L3 puffstage 1-2  (588) larva L3 puffstage 3-6  (815) larva L3 puffstage 7-9  (1136) white prepupae new  (1249) white prepupae 12hr  (928) white prepupae 24hr  (1585) pupae 2d postWPP  (978) pupae 3d postWPP  (289) pupae 4d postWPP  (332) adult male 01day  (321) adult male 05day  (342) adult male 30day  (372) adult female 01day  (564) adult female 05day  (764) adult female 30day  (790) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (941) embryo 02-04hr  (295) embryo 04-06hr  (322) embryo 06-08hr  (732) embryo 08-10hr  (840) embryo 10-12hr  (1584) embryo 12-14hr  (828) embryo 14-16hr  (769) embryo 16-18hr  (445) embryo 18-20hr  (310) embryo 20-22hr  (176) embryo 22-24hr  (158) larva L1  (417) larva L2  (992) larva L3 12hr old  (669) larva L3 puffstage 1-2  (588) larva L3 puffstage 3-6  (815) larva L3 puffstage 7-9  (1136) white prepupae new  (1249) white prepupae 12hr  (928) white prepupae 24hr  (1585) pupae 2d postWPP  (978) pupae 3d postWPP  (289) pupae 4d postWPP  (332) adult male 01day  (321) adult male 05day  (342) adult male 30day  (372) adult female 01day  (564) adult female 05day  (764) adult female 30day  (790) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    941 embryo 02-04hr    295 embryo 04-06hr    322 embryo 06-08hr    732 embryo 08-10hr    840 embryo 10-12hr    1584 embryo 12-14hr    828 embryo 14-16hr    769 embryo 16-18hr    445 embryo 18-20hr    310 embryo 20-22hr    176 embryo 22-24hr    158 larva L1    417 larva L2    992 larva L3 12hr old    669 larva L3 puffstage 1-2    588 larva L3 puffstage 3-6    815 larva L3 puffstage 7-9    1136 white prepupae new    1249 white prepupae 12hr    928 white prepupae 24hr    1585 pupae 2d postWPP    978 pupae 3d postWPP    289 pupae 4d postWPP    332 adult male 01day    321 adult male 05day    342 adult male 30day    372 adult female 01day    564 adult female 05day    764 adult female 30day    790 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    388 Schneider line 2 Sg4    858 embryonic 1182-4H    355 embryonic GM2    206 embryonic Kc167    171 embryonic S1    465 embryonic S3    516 leg disc CME L1    572 wing disc CME-W2    262 wing disc ML-DmD8    335 wing disc ML-DmD9    409 wing disc ML-DmD16-c3    289 wing disc ML-DmD21    1066 wing disc ML-DmD32    293 haltere disc ML-DmD17-c3    290 eye-antennal disc ML-DmD11    475 antennal disc ML-DmD20-c5    862 mixed discs ML-DmD4-c1    480 CNS ML-DmBG1-c1    534 CNS ML-DmBG2-c2    241 tumorous blood cells mbn2    184 ovary fGS/OSS    140 ovary OSC    86 ovary OSS    84 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (388) Schneider line 2 Sg4  (858) embryonic 1182-4H  (355) embryonic GM2  (206) embryonic Kc167  (171) embryonic S1  (465) embryonic S3  (516) leg disc CME L1  (572) wing disc CME-W2  (262) wing disc ML-DmD8  (335) wing disc ML-DmD9  (409) wing disc ML-DmD16-c3  (289) wing disc ML-DmD21  (1066) wing disc ML-DmD32  (293) haltere disc ML-DmD17-c3  (290) eye-antennal disc ML-DmD11  (475) antennal disc ML-DmD20-c5  (862) mixed discs ML-DmD4-c1  (480) CNS ML-DmBG1-c1  (534) CNS ML-DmBG2-c2  (241) tumorous blood cells mbn2  (184) ovary fGS/OSS  (140) ovary OSC  (86) ovary OSS  (84) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (388) Schneider line 2 Sg4  (858) embryonic 1182-4H  (355) embryonic GM2  (206) embryonic Kc167  (171) embryonic S1  (465) embryonic S3  (516) leg disc CME L1  (572) wing disc CME-W2  (262) wing disc ML-DmD8  (335) wing disc ML-DmD9  (409) wing disc ML-DmD16-c3  (289) wing disc ML-DmD21  (1066) wing disc ML-DmD32  (293) haltere disc ML-DmD17-c3  (290) eye-antennal disc ML-DmD11  (475) antennal disc ML-DmD20-c5  (862) mixed discs ML-DmD4-c1  (480) CNS ML-DmBG1-c1  (534) CNS ML-DmBG2-c2  (241) tumorous blood cells mbn2  (184) ovary fGS/OSS  (140) ovary OSC    86 ovary OSS    84 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    388 Schneider line 2 Sg4    858 embryonic 1182-4H    355 embryonic GM2    206 embryonic Kc167    171 embryonic S1    465 embryonic S3    516 leg disc CME L1    572 wing disc CME-W2    262 wing disc ML-DmD8    335 wing disc ML-DmD9    409 wing disc ML-DmD16-c3    289 wing disc ML-DmD21    1066 wing disc ML-DmD32    293 haltere disc ML-DmD17-c3    290 eye-antennal disc ML-DmD11    475 antennal disc ML-DmD20-c5    862 mixed discs ML-DmD4-c1    480 CNS ML-DmBG1-c1    534 CNS ML-DmBG2-c2    241 tumorous blood cells mbn2    184 ovary fGS/OSS    140 ovary OSC    86 ovary OSS    84 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    388 Schneider line 2 Sg4    858 embryonic 1182-4H    355 embryonic GM2    206 embryonic Kc167    171 embryonic S1    465 embryonic S3    516 leg disc CME L1    572 wing disc CME-W2    262 wing disc ML-DmD8    335 wing disc ML-DmD9    409 wing disc ML-DmD16-c3    289 wing disc ML-DmD21    1066 wing disc ML-DmD32    293 haltere disc ML-DmD17-c3    290 eye-antennal disc ML-DmD11    475 antennal disc ML-DmD20-c5    862 mixed discs ML-DmD4-c1    480 CNS ML-DmBG1-c1    534 CNS ML-DmBG2-c2    241 tumorous blood cells mbn2    184 ovary fGS/OSS    140 ovary OSC    86 ovary OSS    84 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (388) Schneider line 2 Sg4  (858) embryonic 1182-4H  (355) embryonic GM2  (206) embryonic Kc167  (171) embryonic S1  (465) embryonic S3  (516) leg disc CME L1  (572) wing disc CME-W2  (262) wing disc ML-DmD8  (335) wing disc ML-DmD9  (409) wing disc ML-DmD16-c3  (289) wing disc ML-DmD21  (1066) wing disc ML-DmD32  (293) haltere disc ML-DmD17-c3  (290) eye-antennal disc ML-DmD11  (475) antennal disc ML-DmD20-c5  (862) mixed discs ML-DmD4-c1  (480) CNS ML-DmBG1-c1  (534) CNS ML-DmBG2-c2  (241) tumorous blood cells mbn2  (184) ovary fGS/OSS  (140) ovary OSC  (86) ovary OSS  (84) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (388) Schneider line 2 Sg4  (858) embryonic 1182-4H  (355) embryonic GM2  (206) embryonic Kc167  (171) embryonic S1  (465) embryonic S3  (516) leg disc CME L1  (572) wing disc CME-W2  (262) wing disc ML-DmD8  (335) wing disc ML-DmD9  (409) wing disc ML-DmD16-c3  (289) wing disc ML-DmD21  (1066) wing disc ML-DmD32  (293) haltere disc ML-DmD17-c3  (290) eye-antennal disc ML-DmD11  (475) antennal disc ML-DmD20-c5  (862) mixed discs ML-DmD4-c1  (480) CNS ML-DmBG1-c1  (534) CNS ML-DmBG2-c2  (241) tumorous blood cells mbn2  (184) ovary fGS/OSS  140 ovary OSC    86 ovary OSS    84 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    388 Schneider line 2 Sg4    858 embryonic 1182-4H    355 embryonic GM2    206 embryonic Kc167    171 embryonic S1    465 embryonic S3    516 leg disc CME L1    572 wing disc CME-W2    262 wing disc ML-DmD8    335 wing disc ML-DmD9    409 wing disc ML-DmD16-c3    289 wing disc ML-DmD21    1066 wing disc ML-DmD32    293 haltere disc ML-DmD17-c3    290 eye-antennal disc ML-DmD11    475 antennal disc ML-DmD20-c5    862 mixed discs ML-DmD4-c1    480 CNS ML-DmBG1-c1    534 CNS ML-DmBG2-c2    241 tumorous blood cells mbn2    184 ovary fGS/OSS    140 ovary OSC    86 ovary OSS    84 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    370 cold shock, 4-day adult    305 heat shock, 4-day adult    477 Cadmium 50 mM 6 hrs, larvae L3    665 Cadmium 50 mM 12 hrs, larvae L3    544 Cadmium 50 mM 48 hrs, 4-day adult    293 Cadmium 100 mM 48 hrs, 4-day adult    256 Copper 0.5 mM 12 hrs, larvae L3    367 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    299 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    539 Ethanol 5% 3 hrs, larvae L3    377 Ethanol 10% 3 hrs, larvae L3    511 Caffeine 1.5 mg/ml 4 hrs, larvae L3    316 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    240 Caffeine 25 mg/ml 48 hrs, 4-day adult    238 Paraquat 5 mM 48 hrs, 4-day adult    310 Paraquat 10 mM 48 hrs, 4-day adult    318 Rotenone 2 μg 12 hrs, larvae L3    438 Rotenone 8 μg 12 hrs, larvae L3    556 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (370) cold shock, 4-day adult  (305) heat shock, 4-day adult  (477) Cadmium 50 mM 6 hrs, larvae L3  (665) Cadmium 50 mM 12 hrs, larvae L3  (544) Cadmium 50 mM 48 hrs, 4-day adult  (293) Cadmium 100 mM 48 hrs, 4-day adult  (256) Copper 0.5 mM 12 hrs, larvae L3  (367) Copper 15 mM 48 hrs, 4-day adult  (49) Zinc 5 mM 12 hrs, larvae L3  (299) Zinc 4.5 mM 48 hrs, 4-day adult  (78) Ethanol 2.5% 3 hrs, larvae L3  (539) Ethanol 5% 3 hrs, larvae L3  (377) Ethanol 10% 3 hrs, larvae L3  (511) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (316) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (240) Caffeine 25 mg/ml 48 hrs, 4-day adult  (238) Paraquat 5 mM 48 hrs, 4-day adult  (310) Paraquat 10 mM 48 hrs, 4-day adult  (318) Rotenone 2 μg 12 hrs, larvae L3  (438) Rotenone 8 μg 12 hrs, larvae L3  (556) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (370) cold shock, 4-day adult  (305) heat shock, 4-day adult  (477) Cadmium 50 mM 6 hrs, larvae L3  (665) Cadmium 50 mM 12 hrs, larvae L3  (544) Cadmium 50 mM 48 hrs, 4-day adult  (293) Cadmium 100 mM 48 hrs, 4-day adult  (256) Copper 0.5 mM 12 hrs, larvae L3  (367) Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3  (299) Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3  (539) Ethanol 5% 3 hrs, larvae L3  (377) Ethanol 10% 3 hrs, larvae L3  (511) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (316) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (240) Caffeine 25 mg/ml 48 hrs, 4-day adult  (238) Paraquat 5 mM 48 hrs, 4-day adult  (310) Paraquat 10 mM 48 hrs, 4-day adult  (318) Rotenone 2 μg 12 hrs, larvae L3  (438) Rotenone 8 μg 12 hrs, larvae L3  (556) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    370 cold shock, 4-day adult    305 heat shock, 4-day adult    477 Cadmium 50 mM 6 hrs, larvae L3    665 Cadmium 50 mM 12 hrs, larvae L3    544 Cadmium 50 mM 48 hrs, 4-day adult    293 Cadmium 100 mM 48 hrs, 4-day adult    256 Copper 0.5 mM 12 hrs, larvae L3    367 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    299 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    539 Ethanol 5% 3 hrs, larvae L3    377 Ethanol 10% 3 hrs, larvae L3    511 Caffeine 1.5 mg/ml 4 hrs, larvae L3    316 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    240 Caffeine 25 mg/ml 48 hrs, 4-day adult    238 Paraquat 5 mM 48 hrs, 4-day adult    310 Paraquat 10 mM 48 hrs, 4-day adult    318 Rotenone 2 μg 12 hrs, larvae L3    438 Rotenone 8 μg 12 hrs, larvae L3    556 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    370 cold shock, 4-day adult    305 heat shock, 4-day adult    477 Cadmium 50 mM 6 hrs, larvae L3    665 Cadmium 50 mM 12 hrs, larvae L3    544 Cadmium 50 mM 48 hrs, 4-day adult    293 Cadmium 100 mM 48 hrs, 4-day adult    256 Copper 0.5 mM 12 hrs, larvae L3    367 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    299 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    539 Ethanol 5% 3 hrs, larvae L3    377 Ethanol 10% 3 hrs, larvae L3    511 Caffeine 1.5 mg/ml 4 hrs, larvae L3    316 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    240 Caffeine 25 mg/ml 48 hrs, 4-day adult    238 Paraquat 5 mM 48 hrs, 4-day adult    310 Paraquat 10 mM 48 hrs, 4-day adult    318 Rotenone 2 μg 12 hrs, larvae L3    438 Rotenone 8 μg 12 hrs, larvae L3    556 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (370) cold shock, 4-day adult  (305) heat shock, 4-day adult  (477) Cadmium 50 mM 6 hrs, larvae L3  (665) Cadmium 50 mM 12 hrs, larvae L3  (544) Cadmium 50 mM 48 hrs, 4-day adult  (293) Cadmium 100 mM 48 hrs, 4-day adult  (256) Copper 0.5 mM 12 hrs, larvae L3  (367) Copper 15 mM 48 hrs, 4-day adult  (49) Zinc 5 mM 12 hrs, larvae L3  (299) Zinc 4.5 mM 48 hrs, 4-day adult  (78) Ethanol 2.5% 3 hrs, larvae L3  (539) Ethanol 5% 3 hrs, larvae L3  (377) Ethanol 10% 3 hrs, larvae L3  (511) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (316) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (240) Caffeine 25 mg/ml 48 hrs, 4-day adult  (238) Paraquat 5 mM 48 hrs, 4-day adult  (310) Paraquat 10 mM 48 hrs, 4-day adult  (318) Rotenone 2 μg 12 hrs, larvae L3  (438) Rotenone 8 μg 12 hrs, larvae L3  (556) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (370) cold shock, 4-day adult  (305) heat shock, 4-day adult  (477) Cadmium 50 mM 6 hrs, larvae L3  (665) Cadmium 50 mM 12 hrs, larvae L3  (544) Cadmium 50 mM 48 hrs, 4-day adult  (293) Cadmium 100 mM 48 hrs, 4-day adult  (256) Copper 0.5 mM 12 hrs, larvae L3  (367) Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3  (299) Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3  (539) Ethanol 5% 3 hrs, larvae L3  (377) Ethanol 10% 3 hrs, larvae L3  (511) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (316) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (240) Caffeine 25 mg/ml 48 hrs, 4-day adult  (238) Paraquat 5 mM 48 hrs, 4-day adult  (310) Paraquat 10 mM 48 hrs, 4-day adult  (318) Rotenone 2 μg 12 hrs, larvae L3  (438) Rotenone 8 μg 12 hrs, larvae L3  (556) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    370 cold shock, 4-day adult    305 heat shock, 4-day adult    477 Cadmium 50 mM 6 hrs, larvae L3    665 Cadmium 50 mM 12 hrs, larvae L3    544 Cadmium 50 mM 48 hrs, 4-day adult    293 Cadmium 100 mM 48 hrs, 4-day adult    256 Copper 0.5 mM 12 hrs, larvae L3    367 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    299 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    539 Ethanol 5% 3 hrs, larvae L3    377 Ethanol 10% 3 hrs, larvae L3    511 Caffeine 1.5 mg/ml 4 hrs, larvae L3    316 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    240 Caffeine 25 mg/ml 48 hrs, 4-day adult    238 Paraquat 5 mM 48 hrs, 4-day adult    310 Paraquat 10 mM 48 hrs, 4-day adult    318 Rotenone 2 μg 12 hrs, larvae L3    438 Rotenone 8 μg 12 hrs, larvae L3    556 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034753 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2852-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG2852GD6598 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG2852 Class Mutagen Stocks Known lesion CG2852KG00640 1 -- CG2852EP2294 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG2852 Class Mutagen Stocks Known lesion CG2852GD6598 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG2852KK109148 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6598} NA P{KK109148} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG2852EP2294 NA miscellaneous insertions P{SUPor-P}CG2852KG00640 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
multicellular organism reproduction inferred from expression pattern (Findlay et al., 2009, Findlay et al., 2008)
Cellular Component
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004) extracellular space inferred from direct assay (Findlay et al., 2009, Walker et al., 2006, Findlay et al., 2008) lipid particle inferred from direct assay (Beller et al., 2006) microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
peptidyl-prolyl cis-trans isomerase activity inferred from sequence or structural similarity with UniProtKB:P23284 (FlyBase, 1992-)
Biological Process
CV term Evidence References
protein folding inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG2852 - Akap200 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Ald experimental knowledge based (Guruharsha et al., 2011) CG2852 - AnxB10 experimental knowledge based (Guruharsha et al., 2011) CG2852 - B52 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Bacc experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG1024 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG10265 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG10638 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG11267 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG13472 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG13539 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG14715 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG15096 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG1707 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG1910 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG2004 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG2862 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG30339 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG31917 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG3226 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG4598 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG5355 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG5577 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG5726 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG6084 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG6321 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG7091 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG8036 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG8117 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG8132 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - CG8891 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG2852 - CG8993 experimental knowledge based (Guruharsha et al., 2011) CG2852 - CG9705 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Chd64 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Clic experimental knowledge based (Guruharsha et al., 2011) CG2852 - Crc experimental knowledge based (Guruharsha et al., 2011) CG2852 - CtBP anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - D1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Df31 experimental knowledge based (Guruharsha et al., 2011) CG2852 - E(spl)mγ-HLH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Eb1 experimental knowledge based (Guruharsha et al., 2011) CG2852 - EndoGI experimental knowledge based (Guruharsha et al., 2011) CG2852 - Eno experimental knowledge based (Guruharsha et al., 2011) CG2852 - FK506-bp2 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Fkbp13 experimental knowledge based (Guruharsha et al., 2011) CG2852 - GstO3 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Hop experimental knowledge based (Guruharsha et al., 2011) CG2852 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Inos experimental knowledge based (Guruharsha et al., 2011) CG2852 - Lac anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Mdh2 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Moe experimental knowledge based (Guruharsha et al., 2011) CG2852 - Nacα experimental knowledge based (Guruharsha et al., 2011) CG2852 - Nlp experimental knowledge based (Guruharsha et al., 2011) CG2852 - Ntf-2 experimental knowledge based (Guruharsha et al., 2011) CG2852 - PHGPx experimental knowledge based (Guruharsha et al., 2011) CG2852 - Pdi experimental knowledge based (Guruharsha et al., 2011) CG2852 - Pgd experimental knowledge based (Guruharsha et al., 2011) CG2852 - Proct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Prosα1 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Prosα6 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Prx2540-2 experimental knowledge based (Guruharsha et al., 2011) CG2852 - RhoGDI experimental knowledge based (Guruharsha et al., 2011) CG2852 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Sh3β experimental knowledge based (Guruharsha et al., 2011) CG2852 - Snx3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - Sod experimental knowledge based (Guruharsha et al., 2011) CG2852 - Trx-2 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Trxr-1 experimental knowledge based (Guruharsha et al., 2011) CG2852 - Uch experimental knowledge based (Guruharsha et al., 2011) CG2852 - Uev1A experimental knowledge based (Guruharsha et al., 2011) CG2852 - Wwox anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - aur anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - awd experimental knowledge based (Guruharsha et al., 2011) CG2852 - capt experimental knowledge based (Guruharsha et al., 2011) CG2852 - cib experimental knowledge based (Guruharsha et al., 2011) CG2852 - dod experimental knowledge based (Guruharsha et al., 2011) CG2852 - eIF-1A experimental knowledge based (Guruharsha et al., 2011) CG2852 - eIF-5A experimental knowledge based (Guruharsha et al., 2011) CG2852 - fabp experimental knowledge based (Guruharsha et al., 2011) CG2852 - mRpS24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG2852 - mus209 experimental knowledge based (Guruharsha et al., 2011) CG2852 - regucalcin experimental knowledge based (Guruharsha et al., 2011) CG2852 - scu experimental knowledge based (Guruharsha et al., 2011) CG2852 - smt3 experimental knowledge based (Guruharsha et al., 2011) CG2852 - tub anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG2852 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63206 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034753 DroID - A comprehensive database of gene and protein interactions. • FBgn0034753 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37591
Orthologs
OrthoDB Orthologs (48) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61RQFG Dipteran inclusive ortholog search EOG6CRM89 Insect inclusive ortholog search EOG6DZ0RK Arthropod inclusive ortholog search EOG6V41R1 Metazoa inclusive ortholog search EOG6742MZ
Orthologs in Drosophila Species (EOG61RQFG)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG2852     Drosophila simulans   Dsim\GD25116 Y   Drosophila sechellia   Dsec\GM15627 Y   Drosophila erecta   Dere\GG21776 Y   Drosophila yakuba   Dyak\GE11851 Y   Drosophila ananassae   Dana\GF13003 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15486 Y   Drosophila persimilis   Dper\GL17482 Y   Drosophila willistoni   Dwil\GK21428 Y   Drosophila virilis   Dvir\GJ21252 Y   Drosophila mojavensis   Dmoj\moj29 Y   Drosophila grimshawi   Dgri\GH20332 Y
Orthologs in non-Drosophila Dipterans (EOG6CRM89)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013279   Anopheles gambiae Malaria mosquito  Agam\AGAP007088   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004991
Orthologs in non-Dipteran Insects (EOG6DZ0RK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46652   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG014370   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16971   Atta cephalotes Leafcutter ant  Acep\ACEP21408   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14493   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15643   Linepithema humile Argentine ant  Lhum\LH10753   Pogonomyrmex barbatus Red harvester ant  Pbar\PB18617   Solenopsis invicta Red fire ant  Sinv\SINV20981   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004891   Bombyx mori Silkmoth  Bmor\BGIBMGA004059   Pediculus humanus Human body louse  Phum\PHUM371420   Tribolium castaneum Red flour beetle  Tcas\TC014505
Orthologs in non-Insect Arthropods (EOG6V41R1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_299901   Ixodes scapularis Deer tick  Isca\ISCW011314
Orthologs in non-Arthropod Metazoa (EOG6742MZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\cyn-6 Y Caenorhabditis elegans Nematode  Cele\cyn-5 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028874gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013756gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004626gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007484gn Y Danio rerio Zebrafish  Drer\ENSDARG00000053219 Y Danio rerio Zebrafish  Drer\ppib Y Xenopus tropicalis Western clawed frog  Xtro\ppib Y Xenopus tropicalis Western clawed frog  Xtro\ppic Y Gallus gallus Domestic chicken  Ggal\PPIC Y Gallus gallus Domestic chicken  Ggal\PPIB Y Mus musculus House mouse  Mmus\Ppib Y Mus musculus House mouse  Mmus\Ppic Y Rattus norvegicus Norway rat  Rnor\Ppic Y Rattus norvegicus Norway rat  Rnor\Ppib Y Homo sapiens Human  Hsap\PPIC Y Homo sapiens Human  Hsap\PPIB Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\PPIC     Hsap\PPIB
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25116 Drosophila sechellia Dsec\GM15627 Drosophila erecta Dere\GG21776 Drosophila yakuba Dyak\GE11851 Drosophila ananassae Dana\GF13003 Drosophila pseudoobscura pseudoobscura Dpse\GA15486 Drosophila persimilis Dper\GL17482 Drosophila willistoni Dwil\GK21428 Drosophila virilis Dvir\GJ21252 Drosophila mojavensis Dmoj\moj29 Drosophila grimshawi Dgri\GH20332
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	13395 y1 w67c23; P{SUPor-P}CG2852KG00640
VDRC	v102376 P{KK109148}VIE-260B v15069 w1118; P{GD6598}v15069
Genomic Clones ( 1 )
	BACR11M08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 191 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP04623 RE50843
Other clones	DPiM_RE50843 yak-ad_CG2852 yak-em_CG2852
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT10177 AT16034 GH03331 GH03635 GH08563 GH14929 GH19330 GH24873 GH28323 GM03772 GM05310 GM10491 GM14027 GM18394 GM23380 GM24331 GM25147 GM32667 LD13181 LD31168 LD33968 LD33969 LP02141 LP03604 LP04302 LP05228 LP05283 LP06429 LP06484 LP08143 LP08669 LP09588 LP11037 LP11041 LP13490 LP14476 LP20810 LP21575 LP21964 LP22817 LP23347 RE14778 RE16374 RE17560 RE35684 RE36625 RE37782 RE38282 RE42206 RE43457 RE46079 RE48417 RE48943 RE53390 RE53603 RE54559 RE55093 RE55355 RE56047 RE64947 RH10043 RH17248 RH26389 RH26434 RH26728 RH27484 RH27674 RH33366 RH34031 RH34371 RH37682 RH49889 RH50134 RH50448 RH51095 RH52476 RH64049 RH71485 RH71556 SD12236 SD17906 SD18696 SD20040 SD23436 UT01334
Other clones	8215 38402 98227 161235 274646 523678 524358 542456 562242 CK01.7C.A10 CK01.60C.D5 CK01.67B.H9 CK01.118C.C10 CK01.120B.F7 Dmel_dig_001230_0640_3669 Dmel_dig_004935_0631_1640 Dmel_dig_009560_0707_1244 Dmel_dig_014172_0685_1013 Dmel_dig_019744_0664_2361 Dmel_neb_001936_0830_3697 Dmel_neb_006575_0437_2904 Dmel_neb_014900_0394_1759 EC24052 EC25335 EC27949 EC28225 EC32150 EK048815 EK054229 EK063615 EK089941 EK091824 EK106750 EK166016 EK218905 EK221243 EK250905 EK302020 EN04062 EN05233 EN10642 EN13954 ESG016b.E21_E04 ESG017b.E21_E06 ESG017d.E21_D09 ESG0114b.B21_F09 FGH121C04 FGH123F04 FGM002C06 FGM004C11 FGM101D04 FGM210D09 FGM213G04 FGM214A08 FGM216E10 FGM221A11 RP004055478 RP004090718 RP004101386 RP004149943 RP004208616 RP004209314 RP004210727 RP004211348 RP004212915 RP004220899 RP004226863 RP004231624 RP004237221 RP004242408 RP004244806 RP004244936 RP004245941 RP004247477 RP004247539 RP004253225 RP004257928 RP004263925 RP004265490 RP004286339 RP004293906 RP004361986 RP004370977 RP004380217 RP004385238 RP004386559 RP004407612 RP004416792 RP004451981 RP004454765 RP004459389 RP004462576 RP004462935 RP004489814 RP004505791 RP004523801 RP004527804 RP004529136 RP004538244 RP004541386 RP004544027
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034753 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37591
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	"CG2852" may correspond to "Scim29". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim29" near/in "CG13513" or "CG2852". (Dobie and Karpen, 2001.4.18)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137851 RefSeq (Proteins) • NP_611695 DDBJ / EMBL / GenBank • AAF46873 AAX33414 AI260670 BI365505 BT021266 Entrez Gene - A searchable database of RefSeq genes. • 37591 UniProtKB/TrEMBL • Q9W227
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain (IPR002130) Cyclophilin-type peptidyl-prolyl cis-trans isomerase (IPR024936) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (IPR020892)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63206 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034753 DroID - A comprehensive database of gene and protein interactions. • FBgn0034753 DRSC - Results from RNAi screens. • FBgn0034753 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034753 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2852-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034753 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37591 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37591 modMine - Data generated by the modENCODE project. • FBgn0034753
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG2852 (Beller et al., 2006, Altenhein et al., 2006, Ravi Ram and Wolfner, 2007, McGraw et al., 2008, O'Keefe et al., 2011, Findlay et al., 2009, Keleman et al., 2009.8.5, Hughes et al., 2008, Pospisilik et al., 2010, Walker et al., 2006, Cammarato et al., 2011, Fisher et al., 2008, Gurudatta et al., 2012)
Name Synonym
Secondary FlyBase IDs
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 11 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 3 ) Curated genome annotation  ( 2 )
Recent research papers ( 3 )
	Gurudatta et al., 2012, Dev. Biol. 369(1): 124--132 The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. [FBrf0219796] Dottorini et al., 2011, BMC Bioinformatics 12: 34 Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. [FBrf0214379] O'Keefe et al., 2011, Hum. Mol. Genet. 20(3): 497--509 Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. [FBrf0212691] Show all research papers ...