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Gene Dmel\RYBP

General Information
Symbol	Dmel\RYBP	Species	D. melanogaster
Name	Ring and YY1 Binding Protein	Annotation symbol	CG12190
Feature type	protein_coding_gene	FlyBase ID	FBgn0034763
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	dRYBP
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	58F7-58F7	Sequence location	2R:18,558,252..18,560,717 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ring and YY1 Binding Protein is referred to in FlyBase by the symbol Dmel\RYBP (CG12190, FBgn0034763). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotypes of these alleles are annotated with: adult segment; organ system subdivision; organ system; thoracic segment; adult; region of integument; embryonic/larval integumentary system; prothoracic segment; trichome field; denticle field. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, RanBP2-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1628977_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RYBP. Gene sequence location is 2R:18558257..18560717.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 58F7-58F7   Limits computationally determined from genome sequence between P{EP}EP718EP718 and P{EP}ppaEP698&P{EP}EP2184
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RYBP for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RYBP-RA FBtr0071868  NM_137861   2082   150
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RYBP-PA   FBpp0071779   16.9   150   11.05     NP_611705   AAF46885
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, RanBP2-type (IPR001876)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264271   AA392063   AA441289   AA538572   AA539061   AA540826   AE013599 AAF46885   AI387539   AW942497   AY069460 AAL39605   BI164697   BI168707   BI169560   BI169898   BI213104   BI213999   BI243276   BI367655   BI580415   BI632961   BI639980   BP557017   BZ286320   CK660474   CO182171   CO189197   CO275717   CO284425   CO302181   CO302189   CO317802   CO342720   CZ466663   EC066682   EC073173   EC074298   EC080751   EC085750   EC250475   EV599040   GH764687
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W215
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
nuclear body inferred from direct assay (González et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    210.225 Larval Midgut    47.8 Larval Hindgut    68.6 Larval Malpighian Tubules    134.5 Larval Fat Body    60.9 Larval Salivary Gland    67.3 Larval Trachea    80.025 Larval Carcass    66.175 Adult Head    63.5 Adult Eye    74.875 Adult Brain    184.4 Adult Thoracic-Abdominal Ganglion    177 Adult Crop    55.5 Adult Midgut    34.4 Adult Hindgut    53.5 Adult Malpighian Tubules    34 Adult Fat Body    54.2 Adult Salivary Gland    66.2 Adult Heart    40.975 Adult VirginFemale Spermatheca    43 Adult InseminatedFemale Spermatheca    49.3 Adult Ovary    89.8 Adult Testis    13.8 Adult Male Accessory Gland    55.6 Adult Carcass    51.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    63.5   NA  Eye    74.875   NA  Brain    184.4   210.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    177   NA  Crop    55.5   47.8  Midgut    34.4   68.6  Hindgut    53.5   134.5  Malpighian Tubules    34   60.9  Fat Body    54.2   67.3  Salivary Gland    no informative data   NA  Heart    40.975   80.025  Trachea    NA   NA  VirginFemale Spermatheca    43   NA  InseminatedFemale Spermatheca    49.3   NA  Ovary    89.8   NA  Testis    no informative data   NA  Male Accessory Gland    55.6   66.175  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3  (39) central nervous system, pupae P8  (80) head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae  (48) digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8  (35) carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female  (33) ovary, mated 4-day female  (29) testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3  (39) central nervous system, pupae P8  (80) head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae  (48) digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8  (35) carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female  (33) ovary, mated 4-day female  29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    23 central nervous system, larvae L3    39 central nervous system, pupae P8    80 head, virgin 1-day female    12 head, virgin 4-day female    15 head, virgin 20-day female    7 head, mated 1-day female    12 head, mated 4-day female    11 head, mated 20-day female    7 head, mated 1-day male    16 head, mated 4-day male    24 head, mated 20-day male    16 salivary gland, larvae L3 wandering    16 salivary gland, white prepupae    48 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    14 fat body, pupae P8    35 carcass, larvae L3 wandering    19 carcass, 1-day adult    6 carcass, 4-day adult    7 carcass, 20-day adult    6 ovary, virgin 4-day female    33 ovary, mated 4-day female    29 testis, mated 4-day male    7 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (53) embryo 02-04hr    22 embryo 04-06hr  26 embryo 06-08hr  (28) embryo 08-10hr  (28) embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr  26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day  (35) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (53) embryo 02-04hr    22 embryo 04-06hr  26 embryo 06-08hr  28 embryo 08-10hr  28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr  26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day  (35) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    22 embryo 04-06hr    26 embryo 06-08hr    28 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    22 embryo 14-16hr    14 embryo 16-18hr    12 embryo 18-20hr    10 embryo 20-22hr    8 embryo 22-24hr    10 larva L1    8 larva L2    7 larva L3 12hr old    5 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    25 white prepupae new    25 white prepupae 12hr    23 white prepupae 24hr    26 pupae 2d postWPP    23 pupae 3d postWPP    12 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    11 adult male 30day    9 adult female 01day    16 adult female 05day    35 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2  (38) embryonic Kc167  (43) embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2  (38) embryonic Kc167  (43) embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    9 embryonic 1182-4H    12 embryonic GM2    38 embryonic Kc167    43 embryonic S1    22 embryonic S3    22 leg disc CME L1    12 wing disc CME-W2    18 wing disc ML-DmD8    10 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    8 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    15 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    21 ovary fGS/OSS    19 ovary OSC    24 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult  26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    26 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    14 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	BDGP expression data • LD18758 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034763 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12190-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal RYBPΔ55 lethal | embryonic stage RYBPKG08683 lethal | embryonic stage, with Scer\GAL4en-e16E RYBPdsRNA.Scer\UAS.cGa lethal | larval stage, with Scer\GAL4en-e16E RYBPdsRNA.Scer\UAS.cGa partially lethal - majority die RYBPKG08683 Sterility Allele female fertile RYBPΔ55 female sterile RYBPKG08683 Other Phenotypes Allele developmental rate defective | larval stage RYBPKG08683 visible RYBPKG08683 RYBPΔ55 visible, with Scer\GAL4arm.PS RYBPScer\UAS.cBa visible, with Scer\GAL4ci.PC RYBPdsRNA.Scer\UAS.cGa visible, with Scer\GAL4en-e16E RYBPdsRNA.Scer\UAS.cGa visible, with Scer\GAL4sd-SG29.1 RYBPΔZF.Scer\UAS visible, with Scer\GAL4Ubx-lac1-Gal4 RYBPScer\UAS.cBa RYBPΔZF.Scer\UAS visible | somatic clone RYBPKG08683 Phenotype manifest in Allele abdominal sternite 6 | male RYBPKG08683 adult abdominal segment 1 | male, with Scer\GAL4arm.PS RYBPScer\UAS.cBa adult abdominal segment 4 | male, with Scer\GAL4arm.PS RYBPScer\UAS.cBa denticle belt, with Scer\GAL4en-e16E RYBPdsRNA.Scer\UAS.cGa haltere, with Scer\GAL4sd-SG29.1 RYBPΔZF.Scer\UAS haltere, with Scer\GAL4Ubx-lac1-Gal4 RYBPΔZF.Scer\UAS haltere trichome | ectopic, with Scer\GAL4sd-SG29.1 RYBPΔZF.Scer\UAS humerus, with Scer\GAL4en-e16E RYBPScer\UAS.cBa leg RYBPKG08683 mesothoracic leg RYBPΔ55 mesothoracic leg, with Scer\GAL4arm.PS RYBPScer\UAS.cBa metathoracic leg, with Scer\GAL4arm.PS RYBPScer\UAS.cBa metathoracic leg, with Scer\GAL4Ubx-lac1-Gal4 RYBPScer\UAS.cBa organism | embryonic stage RYBPKG08683 scutellum, with Scer\GAL4en-e16E RYBPScer\UAS.cBa scutum, with Scer\GAL4en-e16E RYBPScer\UAS.cBa sex comb | ectopic, with Scer\GAL4arm.PS RYBPScer\UAS.cBa sex comb | ectopic, with Scer\GAL4Ubx-lac1-Gal4 RYBPScer\UAS.cBa trichome & haltere | ectopic, with Scer\GAL4en-e16E RYBPScer\UAS.cBa trichome & haltere | ectopic, with Scer\GAL4sd-SG29.1 RYBPScer\UAS.cBa trichome of the posterior wing margin, with Scer\GAL4en-e16E RYBPScer\UAS.cBa triple row, with Scer\GAL4sd-SG29.1 RYBPScer\UAS.cBa wing RYBPKG08683 RYBPΔ55 wing, with Scer\GAL4ci.PC RYBPdsRNA.Scer\UAS.cGa wing, with Scer\GAL4en-e16E RYBPdsRNA.Scer\UAS.cGa wing, with Scer\GAL4sd-SG29.1 RYBPScer\UAS.cBa RYBPΔZF.Scer\UAS wing | ectopic, with Scer\GAL4en-e16E RYBPScer\UAS.cBa wing | somatic clone RYBPKG08683 wing hair, with Scer\GAL4en-e16E RYBPScer\UAS.cBa wing hair, with Scer\GAL4sd-SG29.1 RYBPScer\UAS.cBa wing hair | ectopic, with Scer\GAL4sd-SG29.1 RYBPΔZF.Scer\UAS wing hair | ectopic, with Scer\GAL4Ubx-lac1-Gal4 RYBPΔZF.Scer\UAS wing vein, with Scer\GAL4sd-SG29.1 RYBPScer\UAS.cBa wing vein L4, with Scer\GAL4en-e16E RYBPScer\UAS.cBa wing vein L5 | distal RYBPKG08683 RYBPΔ55
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of RYBP Class Mutagen Stocks Known lesion RYBPc00702 piggyBac transposase 1 -- RYBPKG08683 loss of function allele P-element activity 1 Yes RYBPMI03416 1 -- RYBPΔ16 Delta2-3 0 Yes RYBPΔ55 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RYBP Class Mutagen Stocks Known lesion RYBPGD7523 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RYBPHMS00931 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RYBPKK107782 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RYBPdsRNA.Scer\UAS.cGa in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes RYBPhs.T:Scer\GAL4.DB in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes RYBPScer\UAS.cBa in vitro construct - regulatory fusion 0 Yes RYBPΔCt.Scer\UAS in vitro construct - regulatory fusion 0 Yes RYBPΔZF.Scer\UAS in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)58B3-59 (González et al., 2008)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK107782} NA P{TRiP.HMS00931} NA P{UAS-RYBP.B} NA P{UAS-RYBP.RNAi} NA P{UAS-RYBP.ΔCt} NA P{UAS-RYBP.ΔZF} NA GAL4 construct P{hs-GAL4.DB.RYBP} No heat-shock construct P{hs-GAL4.DB.RYBP} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}RYBPMI03416 NA P{SUPor-P}RYBPKG08683 NA P{SUPor-P-Δ16}RYBPΔ16 NA PBac{PB}RYBPc00702 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nuclear body inferred from direct assay (González et al., 2008)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
zinc ion binding inferred from electronic annotation with InterPro:IPR001876 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
RYBP - Sce anti bait coimmunoprecipitation, western blot (González et al., 2008) RYBP - pho pull down, western blot (González et al., 2008)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RYBP allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63216 DroID - A comprehensive database of gene and protein interactions. • FBgn0034763 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37601
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69S6T0 Dipteran inclusive ortholog search EOG6P8FTJ Insect inclusive ortholog search EOG68PKH2 Arthropod inclusive ortholog search EOG659ZZD Metazoa inclusive ortholog search EOG6SR8S3
Orthologs in Drosophila Species (EOG69S6T0)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RYBP     Drosophila simulans   Dsim\GD11693 Y   Drosophila sechellia   Dsec\GM15940 Y   Drosophila erecta   Dere\GG22783 Y   Drosophila yakuba   Dyak\GE14012 Y   Drosophila ananassae   Dana\GF11639 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11466 Y   Drosophila persimilis   Dper\GL11369 Y   Drosophila willistoni   Dwil\GK21447 Y   Drosophila virilis   Dvir\GJ22038 Y   Drosophila mojavensis   Dmoj\GI20311 Y   Drosophila grimshawi   Dgri\GH19772 Y
Orthologs in non-Drosophila Dipterans (EOG6P8FTJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008263   Anopheles gambiae Malaria mosquito  Agam\AGAP010288   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008195
Orthologs in non-Dipteran Insects (EOG68PKH2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RYBP   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG017087   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG017088   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12496   Atta cephalotes Leafcutter ant  Acep\ACEP14500   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23432   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20958   Linepithema humile Argentine ant  Lhum\LH17631   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23306   Pediculus humanus Human body louse  Phum\PHUM359160   Tribolium castaneum Red flour beetle  Tcas\TC009493
Orthologs in non-Insect Arthropods (EOG659ZZD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_112486   Ixodes scapularis Deer tick  Isca\ISCW017896
Orthologs in non-Arthropod Metazoa (EOG6SR8S3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011175gn   Danio rerio Zebrafish  Drer\rybpb   Danio rerio Zebrafish  Drer\rybpa   Danio rerio Zebrafish  Drer\yaf2   Xenopus tropicalis Western clawed frog  Xtro\yaf2   Xenopus tropicalis Western clawed frog  Xtro\rybp   Gallus gallus Domestic chicken  Ggal\RYBP   Gallus gallus Domestic chicken  Ggal\YAF2   Mus musculus House mouse  Mmus\Yaf2   Mus musculus House mouse  Mmus\Rybp   Rattus norvegicus Norway rat  Rnor\Rybp   Rattus norvegicus Norway rat  Rnor\Yaf2   Homo sapiens Human  Hsap\ENSG00000015153   Homo sapiens Human  Hsap\ENSG00000163602
Human Orthologs (2)
Gene OMIM HGNC Hsap\ENSG00000015153     Hsap\ENSG00000163602
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11693 Drosophila sechellia Dsec\GM15940 Drosophila erecta Dere\GG22783 Drosophila yakuba Dyak\GE14012 Drosophila ananassae Dana\GF11639 Drosophila pseudoobscura pseudoobscura Dpse\GA11466 Drosophila persimilis Dper\GL11369 Drosophila willistoni Dwil\GK21447 Drosophila virilis Dvir\GJ22038 Drosophila mojavensis Dmoj\GI20311 Drosophila grimshawi Dgri\GH19772
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	38127 y1 w*; Mi{MIC}RYBPMI03416 33974 y1 sc* v1; P{TRiP.HMS00931}attP2 14968 y1 w67c23; P{SUPor-P}RYBPKG08683/CyO
Harvard	- PBac{PB}RYBPc00702
VDRC	v105283 P{KK107782}VIE-260B v52138 w1118; P{GD7523}v52138
Genomic Clones ( 1 )
	BACR11M08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 36 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD18758
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH18090 LD07967 LD12437 LD16170 LD18134 LD20649 LP19084 RE04421 RE09552 RE10772 RE11203 RE18431 RE19674 RE40858 RE53541 RE74608 SD22720 SD26871
Other clones	38321 59266 59272 164589 177154 CK01.53D.C3 Dmel_neb_015089_0914_0795 EC22205 EK043410 EK118409 EK166027 EK183332 EK183346 EK269117 EP15405 FGM306H02 RP001056026
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034763 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37601
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: RYBP CG12190 (Bejarano et al., 2005)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137861 RefSeq (Proteins) • NP_611705 DDBJ / EMBL / GenBank • AA539061 AAF46885 AAL39605 AW942497 AY069460 BZ286320 CZ466663 Entrez Gene - A searchable database of RefSeq genes. • 37601 UniProtKB/TrEMBL • Q9W215
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, RanBP2-type (IPR001876) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD18758
Linkouts
	BioGRID - A database of protein and genetic interactions • 63216 DroID - A comprehensive database of gene and protein interactions. • FBgn0034763 DRSC - Results from RNAi screens. • FBgn0034763 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034763 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12190-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034763 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37601 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37601 modMine - Data generated by the modENCODE project. • FBgn0034763
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG12190 (Bejarano et al., 2005, Keleman et al., 2009.8.5, González et al., 2008, Ni et al., 2010.12.1) dRYBP (Bejarano et al., 2005, González and Busturia, 2009, González et al., 2008, Wilkinson et al., 2010) RYBP
Name Synonym	CG12190   Ring and YY1 Binding Protein
Secondary FlyBase IDs
References ( 17 )
Research paper	Wilkinson et al., 2010, J. Cell. Biochem. 109(3): 478--486 PcG recruitment by the YY1 REPO domain can be mediated by Yaf2. [FBrf0209787] González and Busturia, 2009, Cell Res. 19(6): 747--757 High levels of dRYBP induce apoptosis in Drosophila imaginal cells through the activation of reaper and the requirement of trithorax, dredd and dFADD. [FBrf0215409] González et al., 2008, Genetics 179(3): 1373--1388 Functional characterization of the dRYBP gene in Drosophila. [FBrf0207353] Bejarano et al., 2005, Mech. Dev. 122(10): 1118--1129 The Drosophila RYBP gene functions as a Polycomb-dependent transcriptional repressor. [FBrf0187978]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2012.3.15, set978.xml set978.xml [FBrf0217771] Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	Kodira, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126678]