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Gene Dmel\RpL37b

General Information
Symbol	Dmel\RpL37b	Species	D. melanogaster
Name	Ribosomal protein L37b	Annotation symbol	CG9873
Feature type	protein_coding_gene	FlyBase ID	FBgn0034822
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	59C4-59C4	Sequence location	2R:18,987,580..18,987,982 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein L37b is referred to in FlyBase by the symbol Dmel\RpL37b (CG9873, FBgn0034822). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: translation. One allele is reported. The phenotype of this allele is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein L37ae/L37e, N-terminal; Ribosomal protein L37e; Ribosomal protein L37e, conserved site; Ribosomal protein, zinc-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1636738_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RpL37b. Gene sequence location is 2R:18987580..18987982.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References Chen et al., 2010, Science 330(6011): Sequence features HFA04584 BKN31319
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 59C4-59C4   Limits computationally determined from genome sequence between P{PZ}l(2)0649606496&P{lacW}l(2)k09913k09913 and P{lacW}l(2)k07136k07136
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpL37b for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpL37b-RA FBtr0071978  NM_137913   403   89
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpL37b-PA   FBpp0071888   10.2   89   12.22     NP_611757   AAF46957
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L37e, conserved site (IPR018267) Ribosomal protein L37ae/L37e, N-terminal (IPR011331) Ribosomal protein, zinc-binding domain (IPR011332) Ribosomal protein L37e (IPR001569)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF46957   BP542466   BT023192   BT023213   BT023224   BT044298
UniProtKB/Swiss-Prot	Q9W1U6
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034822    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034822 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034822 expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr  (124) embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr  (169) embryo 22-24hr  (159) larva L1  (167) larva L2  (133) larva L3 12hr old  (403) larva L3 puffstage 1-2  (647) larva L3 puffstage 3-6  (778) larva L3 puffstage 7-9  (911) white prepupae new  (943) white prepupae 12hr  (1195) white prepupae 24hr  (1280) pupae 2d postWPP  (1155) pupae 3d postWPP  (718) pupae 4d postWPP  (358) adult male 01day  (1445) adult male 05day  (2383) adult male 30day  (1437) adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day  1445 adult male 05day  (2383) adult male 30day  1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034822 expression level Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr  124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr  (169) embryo 22-24hr  (159) larva L1  (167) larva L2  133 larva L3 12hr old  (403) larva L3 puffstage 1-2  (647) larva L3 puffstage 3-6  (778) larva L3 puffstage 7-9  (911) white prepupae new  (943) white prepupae 12hr  (1195) white prepupae 24hr  (1280) pupae 2d postWPP  (1155) pupae 3d postWPP  (718) pupae 4d postWPP  (358) adult male 01day  (1445) adult male 05day  (2383) adult male 30day  (1437) adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day  1445 adult male 05day  2383 adult male 30day  1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    57 embryo 02-04hr    45 embryo 04-06hr    124 embryo 06-08hr    83 embryo 08-10hr    59 embryo 10-12hr    86 embryo 12-14hr    52 embryo 14-16hr    46 embryo 16-18hr    72 embryo 18-20hr    97 embryo 20-22hr    169 embryo 22-24hr    159 larva L1    167 larva L2    133 larva L3 12hr old    403 larva L3 puffstage 1-2    647 larva L3 puffstage 3-6    778 larva L3 puffstage 7-9    911 white prepupae new    943 white prepupae 12hr    1195 white prepupae 24hr    1280 pupae 2d postWPP    1155 pupae 3d postWPP    718 pupae 4d postWPP    358 adult male 01day    1445 adult male 05day    2383 adult male 30day    1437 adult female 01day    6 adult female 05day    51 adult female 30day    9 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034822    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034822 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034822 expression level Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034822 expression level Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    14.85 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body    70 Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    11.7 Adult Eye    16.9 Adult Brain    11.9 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    8.6 Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body    29.4 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis    402.6 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion no informative data Adult Crop     Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    11.7   NA  Eye    16.9   NA  Brain    11.9   14.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    8.6   no informative data  Midgut    no informative data   no informative data  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   70  Fat Body    29.4   no informative data  Salivary Gland    no informative data   NA  Heart    no informative data   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    no informative data   NA  Testis    402.6   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_28
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034822 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9873-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 RpL37bGD15186 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 RpL37bGD15186 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 RpL37bGD15186
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of RpL37b Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpL37b Class Mutagen Stocks Known lesion RpL37bGD15186 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7177 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD15186} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG10338 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with Saccharomyces RPL37A (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 2002.3.1)
Biological Process
CV term Evidence References
translation inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR011332, InterPro:IPR018267 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
cytosolic large ribosomal subunit inferred from sequence or structural similarity with Saccharomyces RPL37A (FlyBase, 1992-) ribosome non-traceable author statement (Swiss-Prot Project Members, 2002.3.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpL37b allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0034822 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37669
Orthologs
Genome-wide drosophilid orthologs	Dana\GF13322 Dere\GG20067 Dsec\GM15582 Dyak\GE11606
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • 34368 Thalassiosira pseudonana (marine diatom) 80452.m00059 Trichomonas vaginalis (parasitic flagellated protozoan) 82490.m00295 Trichomonas vaginalis (parasitic flagellated protozoan) 92030.m00085 Trichomonas vaginalis (parasitic flagellated protozoan) 95287.m00293 Trichomonas vaginalis (parasitic flagellated protozoan) 95940.m00181 Trichomonas vaginalis (parasitic flagellated protozoan) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229406 FBgn0170500 FBgn0112266 FBgn0090354
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v29760 w1118; P{GD15186}v29760
Genomic Clones ( 2 )
	BACR08P09 BACR34K16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 5 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP02862 IP02962 IP03162
Other clones	FI06520
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	FGC013E01
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034822 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37669
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: RpL37b CG9873 (Ashburner and Marygold, 2004.7.2)
Source for database merge of
Additional comments	The RpL37b gene may have been derived from the RpL37a gene by retroposition. (Dai et al., 2006) The RpL37b gene may be derived from the RpL37a gene by retroposition. (Betran et al., 2002)
Other Comments
	Not a Minute gene. (Marygold et al., 2007) Deletions removing RpL37b but no other cytoplasmic ribosomal protein-encoding genes do not show Minute phenotypes. (Marygold et al., 2007) Likely retrogene. (Marygold et al., 2007)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137913 RefSeq (Proteins) • NP_611757 DDBJ / EMBL / GenBank • AAF46957 Entrez Gene - A searchable database of RefSeq genes. • 37669 UniProtKB/Swiss-Prot • Q9W1U6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L37e, conserved site (IPR018267) Ribosomal protein L37ae/L37e, N-terminal (IPR011331) Ribosomal protein, zinc-binding domain (IPR011332) Ribosomal protein L37e (IPR001569)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0034822 DRSC - Results from RNAi screens. • FBgn0034822 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034822 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9873-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034822 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37669 InParanoid A subset of ortholog calls from InParanoid. • 34368 Thalassiosira pseudonana (marine diatom) 80452.m00059 Trichomonas vaginalis (parasitic flagellated protozoan) 82490.m00295 Trichomonas vaginalis (parasitic flagellated protozoan) 92030.m00085 Trichomonas vaginalis (parasitic flagellated protozoan) 95287.m00293 Trichomonas vaginalis (parasitic flagellated protozoan) 95940.m00181 Trichomonas vaginalis (parasitic flagellated protozoan) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37669 modMine - Data generated by the modENCODE project. • FBgn0034822 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229406 FBgn0170500 FBgn0112266 FBgn0090354
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG9873 (Betran et al., 2002, Dai et al., 2006, Wang et al., 2004, Marygold et al., 2007, Chen et al., 2010) RpL37b (Langille and Clark, 2007, Marygold et al., 2007, Bai et al., 2007)
Name Synonym	Ribosomal protein L37b (Ashburner and Marygold, 2004.7.2)
Secondary FlyBase IDs
References ( 19 )
Research paper	Bai et al., 2007, GenomeBiol. 8(1): Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. [FBrf0192134] Langille and Clark, 2007, Genomics 90(3): 334--343 Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. [FBrf0200094] Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Dai et al., 2006, Gene 385: 96--102 Retrogene movement within- and between-chromosomes in the evolution of Drosophila genomes. [FBrf0194437] Wang et al., 2004, GenomeBiol. 5(9): R69 Function-informed transcriptome analysis of Drosophila renal tubule. [FBrf0180324] Betran et al., 2002, Genome Res. 12(12): 1854--1859 Retroposed new genes out of the X in Drosophila. [FBrf0155820]
Supplementary material	Chen et al., 2010, Science 330(6011): Supporting Online Material. [FBrf0216693] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ashburner and Marygold, 2004.7.2, Ribosomal proteins. Ribosomal proteins. [FBrf0178764] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Protein sequence record	Swiss-Prot Project Members, 2002.3.1, UniProtKB: Q9W1U6 Probable 60S ribosomal protein L37-B. [FBrf0151115]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]