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Gene Dmel\wibg

General Information
Symbol	Dmel\wibg	Species	D. melanogaster
Name	within bgcn	Annotation symbol	CG30176
Feature type	protein_coding_gene	FlyBase ID	FBgn0034918
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	Pym
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60A4-60A4	Sequence location	2R:19,743,478..19,744,457 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene within bgcn is referred to in FlyBase by the symbol Dmel\wibg (CG30176, FBgn0034918). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA binding. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Exon junction complex, Pym. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1640905_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of wibg. Gene sequence location is 2R:19743478..19744457.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN32872 BKN45879
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60A4-60A4   Limits computationally determined from genome sequence between P{lacW}eIF6k13214 and P{lacW}kenk11035&P{EP}CG17658EP730
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\wibg for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) wibg-RA FBtr0072233  NM_166627   980   207
Additional Transcript Data & Comments
Reported size (kB)	1 (northern blot) (Lukacsovich et al., 1999) 1.0 (northern blot) (Ohlstein et al., 2000)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein wibg-PA   FBpp0072142   23.4   207   10.56     NP_726372   AAM68273
Additional Polypeptide Data & Comments
Reported size (kDa)	207 (aa) (Lukacsovich et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Exon junction complex, Pym (IPR015362)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA698824   AE013599 AAM68273   AF293388 AAG00610   AJ459405 CAD30676   AY070957 AAL48579   AY071704 AAL49326   BI165833   BI582030   CK661114   CO153975   CO265112   CO267560   CO309973   EC051577   EC072774   EC075988   EC199185   EC263725   EV587796   EV589918
UniProtKB/Swiss-Prot	P82804
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0034918    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0034918 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0034918 expression level Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6528) embryo 02-04hr  (1565) embryo 04-06hr  (1690) embryo 06-08hr  (1334) embryo 08-10hr  (1263) embryo 10-12hr  (1739) embryo 12-14hr  (762) embryo 14-16hr  (738) embryo 16-18hr  (518) embryo 18-20hr  (579) embryo 20-22hr  (763) embryo 22-24hr  (564) larva L1  (1238) larva L2  (890) larva L3 12hr old  (873) larva L3 puffstage 1-2  (766) larva L3 puffstage 3-6  (929) larva L3 puffstage 7-9  (1020) white prepupae new  (822) white prepupae 12hr  (922) white prepupae 24hr  (1094) pupae 2d postWPP  (796) pupae 3d postWPP  (444) pupae 4d postWPP  (423) adult male 01day  (484) adult male 05day  (620) adult male 30day  (578) adult female 01day  (1733) adult female 05day  (3381) adult female 30day  (4127) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6528) embryo 02-04hr  (1565) embryo 04-06hr  (1690) embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr  (1739) embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day  (1733) adult female 05day  (3381) adult female 30day  (4127) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0034918 expression level Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6528) embryo 02-04hr  (1565) embryo 04-06hr  (1690) embryo 06-08hr  (1334) embryo 08-10hr  (1263) embryo 10-12hr  (1739) embryo 12-14hr  (762) embryo 14-16hr  (738) embryo 16-18hr  (518) embryo 18-20hr  (579) embryo 20-22hr  (763) embryo 22-24hr  (564) larva L1  (1238) larva L2  (890) larva L3 12hr old  (873) larva L3 puffstage 1-2  (766) larva L3 puffstage 3-6  (929) larva L3 puffstage 7-9  (1020) white prepupae new  (822) white prepupae 12hr  (922) white prepupae 24hr  (1094) pupae 2d postWPP  (796) pupae 3d postWPP  (444) pupae 4d postWPP  (423) adult male 01day  (484) adult male 05day  (620) adult male 30day  (578) adult female 01day  (1733) adult female 05day  (3381) adult female 30day  (4127) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6528) embryo 02-04hr  1565 embryo 04-06hr  1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr  1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day  1733 adult female 05day  (3381) adult female 30day  (4127) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6528 embryo 02-04hr    1565 embryo 04-06hr    1690 embryo 06-08hr    1334 embryo 08-10hr    1263 embryo 10-12hr    1739 embryo 12-14hr    762 embryo 14-16hr    738 embryo 16-18hr    518 embryo 18-20hr    579 embryo 20-22hr    763 embryo 22-24hr    564 larva L1    1238 larva L2    890 larva L3 12hr old    873 larva L3 puffstage 1-2    766 larva L3 puffstage 3-6    929 larva L3 puffstage 7-9    1020 white prepupae new    822 white prepupae 12hr    922 white prepupae 24hr    1094 pupae 2d postWPP    796 pupae 3d postWPP    444 pupae 4d postWPP    423 adult male 01day    484 adult male 05day    620 adult male 30day    578 adult female 01day    1733 adult female 05day    3381 adult female 30day    4127 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0034918    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0034918 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0034918 expression level Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0034918 expression level Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    276.625 Larval Midgut    74.8 Larval Hindgut    125.4 Larval Malpighian Tubules    125.4 Larval Fat Body    105.6 Larval Salivary Gland    149.5 Larval Trachea    326.125 Larval Carcass    153 Adult Head    85.3 Adult Eye    108.125 Adult Brain    143.1 Adult Thoracic-Abdominal Ganglion    139.2 Adult Crop    120.7 Adult Midgut    79.2 Adult Hindgut    104.9 Adult Malpighian Tubules    61.4 Adult Fat Body    102 Adult Salivary Gland    88.2 Adult Heart    125.075 Adult VirginFemale Spermatheca    85.3 Adult InseminatedFemale Spermatheca    88.9 Adult Ovary    488.2 Adult Testis    98.8 Adult Male Accessory Gland    108 Adult Carcass    83.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    85.3   NA  Eye    108.125   NA  Brain    143.1   276.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    139.2   NA  Crop    120.7   74.8  Midgut    79.2   125.4  Hindgut    104.9   125.4  Malpighian Tubules    61.4   105.6  Fat Body    102   149.5  Salivary Gland    88.2   NA  Heart    125.075   326.125  Trachea    NA   NA  VirginFemale Spermatheca    85.3   NA  InseminatedFemale Spermatheca    88.9   NA  Ovary    488.2   NA  Testis    98.8   NA  Male Accessory Gland    108   153  Carcass    83.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034918 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30176-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 wibgGD10015 lethal | pupal stage, with Scer\GAL4pnr-MD237 wibgGD10015 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of wibg Class Mutagen Stocks Known lesion wibgSH1616 1 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of wibg Class Mutagen Stocks Known lesion wibgGD10015 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes wibgGL00515 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes wibgHMS01488 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes wibghs.PO in vitro construct - regulatory fusion 0 Yes wibgotu.PO in vitro construct - regulatory fusion 0 Yes wibgt4.2 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10015} NA P{TRiP.GL00515} NA P{TRiP.HMS01488} NA heat-shock construct P{hs-wibg.O} NA characterization construct P{otu-wibg.O} NA P{wibgt4.2} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}wibgSH1616 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a biological process term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function
CV term Evidence References
RNA binding inferred from direct assay (Bono et al., 2004)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
cytoplasm inferred from direct assay (Bono et al., 2004)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions wibg allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034918 DroID - A comprehensive database of gene and protein interactions. • FBgn0034918 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37780
Orthologs
Genome-wide drosophilid orthologs	Dsim\GD15199
Curated drosophilid orthologs	Dpse\GA15700
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP005936-PA Anopheles gambiae (mosquito) XP_393591.1 Apis mellifera (honey bee) At1g11400.1 Arabidopsis thaliana (wall cress) 132216 Branchiostoma floridae (lancelet) XP_001899781.1 Brugia malayi (roundworm nematode) BGIBMGA009902-PA Bombyx mori (silk worm) ENSBTAP00000012767 Bos taurus (bovine) ENSBTAP00000041588 Bos taurus (bovine) CN18800 Caenorhabditis brenneri (small nematode) CBP16654 Caenorhabditis briggsae (nematode) CE34095 Caenorhabditis elegans (worm) ENSCAFP00000000113 Canis familiaris (dog) ENSCINP00000013273 Ciona intestinalis (sea squirt) JA01489 Caenorhabditis japonica (nematode) CPIJ006916 Culex pipens (mosquito) ENSCPOP00000016059 Cavia porcellus (guinea pig) 184443 Chlamidomonas reinhardtii (green alga) RP10363 Caenorhabditis remanei (nematode) ENSCSAVP00000016678 Ciona savignyi (sedentary tunicate) 222778 Capitella spl (polychaete worm) 43105 Daphnia pulex (daphnia) ENSDARP00000067667 Danio rerio (zebra fish) ENSECAP00000009678 Equus caballus (horse) ENSGACP00000014170 Gymnopilus aculeatus (mushroom) ENSP00000386156 Homo sapiens (human) 205412 Lottia gigantea (owl limpet) ENSMMUP00000014411 Macaca mulatta (rhesus monkey) ENSMUSP00000067623 Mus musculus (house mouse) XP_001601998.1 Nasonia vitripennis (wasp) ENSORLP00000018960 Oryzias latipes (japanese killifish) LOC_Os03g15560.1 Oryza sativa (asian rice) PFL0450c Plasmodium falciparum (protozoal parasite) PHUM008059-PA Pediculus humanus (human body louse) PP12777 Pristionchus pacificus (nematode) 235045 Physcomitrella patens (moss) ENSPPYP00000005280 Pongo pygmaeus (orangutan) 155521 Phytophthora sojae (root rot pathogen) 181324 Populus trichocarpa (black cottonwood) ENSPTRP00000055814 Pan troglodytes (chimpanzee) ENSRNOP00000050215 Rattus norvegicus (norway rat) 4998433 Sorghum bicolor (sorghum) Smp_091360 Schistosoma mansoni (trematode parasite) XP_001181236.1 Strongylocentrotus purpuratus (purple sea urchin) 22941 Trichoplax adhaerens (metazoa) XP_974312.2 Tribolium castaneum (red flour beetle) ENSTNIP00000015503 Tetraodon nigroviridis (green spotted pufferfish) TP03_0719 Theileria parva (parasitic protozoan) ENSTRUP00000003822 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000047260 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15001 LH21261 FBgn0224380 FBgn0222271 FBgn0213604 FBgn0213187 FBgn0213164 FBgn0213143 FBgn0186869 JGI_V11_43105 CPIJ006916 BGIBMGA009902 ACYPI003553 GB18277 AGAP005936 AAEL012503 PB24058 PHUM258310 GLEAN_05977
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	35746 y1 sc* v1; P{TRiP.HMS01488}attP2 36096 y1 sc* v1; P{TRiP.GL00515}attP40 29502 w*; P{FRT(whs)}G13 P{lacW}wibgSH1616 bgcnSH1616, l(2)SH1616SH1616/CyO
VDRC	v25592 w1118; P{GD10015}v25592 v25593 w1118; P{GD10015}v25593
Genomic Clones ( 1 )
	BACR05F24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE05806 RH19892
Other clones	DPiM_RE05806
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	HL05757 LP20273
Other clones	31583 38149 97673 523004 Dmel_neb_001086_0406_0319 Dmel_neb_001340_0114_3638 EC051577 EK141547 EK150828 EK220056 EN03227
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034918 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37780
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: wibg BEST:HL05757 (Ohlstein et al., 2000)
Additional comments	Annotation CG10330 split into CG30176 (wibg) and part of CG30170 (bgcn) in release 3 of the genome annotation. In addition, release 3 annotation CG30170 (bgcn) contains sequences corresponding to release 2 annotation CG10331. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_166627 RefSeq (Proteins) • NP_726372 DDBJ / EMBL / GenBank • AA698824 AAG00610 AAL48579 AAL49326 AAM68273 AF293388 AJ459405 AY070957 AY071704 BI165833 BI582030 CAD30676 Entrez Gene - A searchable database of RefSeq genes. • 37780 UniProtKB/Swiss-Prot • P82804
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Exon junction complex, Pym (IPR015362)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034918 DroID - A comprehensive database of gene and protein interactions. • FBgn0034918 DRSC - Results from RNAi screens. • FBgn0034918 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034918 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30176-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034918 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37780 InParanoid A subset of ortholog calls from InParanoid. • AGAP005936-PA Anopheles gambiae (mosquito) XP_393591.1 Apis mellifera (honey bee) At1g11400.1 Arabidopsis thaliana (wall cress) 132216 Branchiostoma floridae (lancelet) XP_001899781.1 Brugia malayi (roundworm nematode) BGIBMGA009902-PA Bombyx mori (silk worm) ENSBTAP00000012767 Bos taurus (bovine) ENSBTAP00000041588 Bos taurus (bovine) CN18800 Caenorhabditis brenneri (small nematode) CBP16654 Caenorhabditis briggsae (nematode) CE34095 Caenorhabditis elegans (worm) ENSCAFP00000000113 Canis familiaris (dog) ENSCINP00000013273 Ciona intestinalis (sea squirt) JA01489 Caenorhabditis japonica (nematode) CPIJ006916 Culex pipens (mosquito) ENSCPOP00000016059 Cavia porcellus (guinea pig) 184443 Chlamidomonas reinhardtii (green alga) RP10363 Caenorhabditis remanei (nematode) ENSCSAVP00000016678 Ciona savignyi (sedentary tunicate) 222778 Capitella spl (polychaete worm) 43105 Daphnia pulex (daphnia) ENSDARP00000067667 Danio rerio (zebra fish) ENSECAP00000009678 Equus caballus (horse) ENSGACP00000014170 Gymnopilus aculeatus (mushroom) ENSP00000386156 Homo sapiens (human) 205412 Lottia gigantea (owl limpet) ENSMMUP00000014411 Macaca mulatta (rhesus monkey) ENSMUSP00000067623 Mus musculus (house mouse) XP_001601998.1 Nasonia vitripennis (wasp) ENSORLP00000018960 Oryzias latipes (japanese killifish) LOC_Os03g15560.1 Oryza sativa (asian rice) PFL0450c Plasmodium falciparum (protozoal parasite) PHUM008059-PA Pediculus humanus (human body louse) PP12777 Pristionchus pacificus (nematode) 235045 Physcomitrella patens (moss) ENSPPYP00000005280 Pongo pygmaeus (orangutan) 155521 Phytophthora sojae (root rot pathogen) 181324 Populus trichocarpa (black cottonwood) ENSPTRP00000055814 Pan troglodytes (chimpanzee) ENSRNOP00000050215 Rattus norvegicus (norway rat) 4998433 Sorghum bicolor (sorghum) Smp_091360 Schistosoma mansoni (trematode parasite) XP_001181236.1 Strongylocentrotus purpuratus (purple sea urchin) 22941 Trichoplax adhaerens (metazoa) XP_974312.2 Tribolium castaneum (red flour beetle) ENSTNIP00000015503 Tetraodon nigroviridis (green spotted pufferfish) TP03_0719 Theileria parva (parasitic protozoan) ENSTRUP00000003822 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000047260 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37780 modMine - Data generated by the modENCODE project. • FBgn0034918 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15001 LH21261 FBgn0224380 FBgn0222271 FBgn0213604 FBgn0213187 FBgn0213164 FBgn0213143 FBgn0186869 JGI_V11_43105 CPIJ006916 BGIBMGA009902 ACYPI003553 GB18277 AGAP005936 AAEL012503 PB24058 PHUM258310 GLEAN_05977
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BEST:HL05757   CG10330   CG30176 (Ni et al., 2011.7.19) Pym (Bono et al., 2004, Roignant and Treisman, 2010) PYM (Forler et al., 2004, Bono et al., 2010) UD3 (Lukacsovich et al., 1999) wibg (Bono et al., 2004, Forler et al., 2004, Ayroles et al., 2009)
Name Synonym	undefined 3 (Lukacsovich et al., 1999) within bgcn (Ohlstein et al., 2000)
Secondary FlyBase IDs
	FBgn0027071 FBgn0050176
References ( 20 )
Research paper	Bono et al., 2010, Mol. Cell 37(2): 211--222 Nuclear Import Mechanism of the EJC Component Mago-Y14 Revealed by Structural Studies of Importin 13. [FBrf0209868] Roignant and Treisman, 2010, Cell 143(2): 238--250 Exon Junction Complex Subunits Are Required to Splice Drosophila MAP Kinase, a Large Heterochromatic Gene. [FBrf0212083] Ayroles et al., 2009, Nature Genetics 41(3): 299--307 Systems genetics of complex traits in Drosophila melanogaster. [FBrf0206705] Bono et al., 2004, EMBO Rpts 5(3): 304--310 Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex. [FBrf0174607] Forler et al., 2004, Molec. Cell. Biol. 24(3): 1155--1167 RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. [FBrf0167892] Ohlstein et al., 2000, Genetics 155(4): 1809--1819 The Drosophila cystoblast differentiation factor, benign gonial cell neoplasm, is related to DExH-box proteins and interacts genetically with bag-of-marbles. [FBrf0130002] Lukacsovich et al., 1999, Genomics 57(1): 43--56 The Drosophila melanogaster 60A chromosomal division is extremely dense with functional genes: their sequences, genomic organization, and expression. [FBrf0108232]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Millburn, 2000.10.11, FlyBase error report for PNBP on Wed Oct 11 02:52:51 2000. FlyBase error report for PNBP on Wed Oct 11 02:52:51 2000. [FBrf0131148]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
DNA/RNA sequence record	Izaurralde, 2002.4.30, GenBank/EMBL/DDBJ: AJ459405 Drosophila melanogaster mRNA for PYM protein (pym gene). [FBrf0153330] Ohlstein, 2000.8.3, GenBank/EMBL/DDBJ: AF293388 Drosophila melanogaster WIBG (wibg) mRNA, complete cds. [FBrf0130893]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]