General Information Symbol Dmel\ Dcp1Species D. melanogaster Name Decapping protein 1 Annotation symbol CG11183 Feature type protein_coding_gene FlyBase ID FBgn0034921 Gene Model Status Current Stock availability 6 publicly
available Also Known As dDcp1, Dcp-1 Genomic Location Chromosome (arm) 2R Recombination map Cytogenetic map 60A8-60A8 Sequence location 2R:19,776,465..19,777,788 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Decapping protein 1 is referred to in FlyBase by the symbol
Dmel\Dcp1 (CG11183, FBgn0034921). It is a protein_coding_gene from
Drosophila melanogaster . There is experimental evidence that it has the
molecular function : protein binding. There is experimental evidence that it is involved in the
biological process : nuclear-transcribed mRNA catabolic process; positive regulation of gene silencing by miRNA; regulation of cytoplasmic mRNA processing body assembly; pole plasm oskar mRNA localization; gene silencing by miRNA.
17 alleles are reported . The
phenotype of these alleles is annotated with: cytoplasmic mRNA processing body. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Dcp1-like decapping; Pleckstrin homology-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1636243_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Dcp1. Gene sequence location is
2R:19776465..19777788 .
User Contributed Data
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) inferred from direct assay
inferred from direct assay
inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
219.475
Larval Midgut
88.7
Larval Hindgut
99.6
Larval Malpighian Tubules
90.5
Larval Fat Body
70.3
Larval Salivary Gland
116.9
Larval Trachea
122.15
Larval Carcass
79.425
Adult Head
98.1
Adult Eye
97.05
Adult Brain
131.1
Adult Thoracic-Abdominal Ganglion
108.6
Adult Crop
98.2
Adult Midgut
84.4
Adult Hindgut
83.6
Adult Malpighian Tubules
56.4
Adult Fat Body
71.4
Adult Salivary Gland
110.5
Adult Heart
64.7
Adult VirginFemale Spermatheca
55.8
Adult InseminatedFemale Spermatheca
63.3
Adult Ovary
195.4
Adult Testis
42
Adult Male Accessory Gland
190.1
Adult Carcass
67
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
98.1
NA
Eye
97.05
NA
Brain
131.1
219.475
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
108.6
NA
Crop
98.2
88.7
Midgut
84.4
99.6
Hindgut
83.6
90.5
Malpighian Tubules
56.4
70.3
Fat Body
71.4
116.9
Salivary Gland
110.5
NA
Heart
64.7
122.15
Trachea
NA
NA
VirginFemale Spermatheca
55.8
NA
InseminatedFemale Spermatheca
63.3
NA
Ovary
195.4
NA
Testis
42
NA
Male Accessory Gland
190.1
79.425
Carcass
67
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(29)
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
29
central nervous system, larvae L3
19
central nervous system, pupae P8
7
head, virgin 1-day female
6
head, virgin 4-day female
6
head, virgin 20-day female
7
head, mated 1-day female
5
head, mated 4-day female
4
head, mated 20-day female
7
head, mated 1-day male
9
head, mated 4-day male
7
head, mated 20-day male
10
salivary gland, larvae L3 wandering
2
salivary gland, white prepupae
5
digestive system, larvae L3 wandering
12
digestive system, 1-day adult
8
digestive system, 4-day adult
6
digestive system, 20-day adult
6
fat body, larvae L3 wandering
3
fat body, white prepupae
7
fat body, pupae P8
7
carcass, larvae L3 wandering
14
carcass, 1-day adult
4
carcass, 4-day adult
6
carcass, 20-day adult
7
ovary, virgin 4-day female
26
ovary, mated 4-day female
20
testis, mated 4-day male
16
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(48)
embryo 02-04hr
(39)
embryo 04-06hr
(37)
embryo 06-08hr
(31)
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
(30)
adult female 30day
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(48)
embryo 02-04hr
(39)
embryo 04-06hr
(37)
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
48
embryo 02-04hr
39
embryo 04-06hr
37
embryo 06-08hr
31
embryo 08-10hr
22
embryo 10-12hr
23
embryo 12-14hr
11
embryo 14-16hr
14
embryo 16-18hr
11
embryo 18-20hr
11
embryo 20-22hr
12
embryo 22-24hr
9
larva L1
17
larva L2
16
larva L3 12hr old
14
larva L3 puffstage 1-2
13
larva L3 puffstage 3-6
18
larva L3 puffstage 7-9
21
white prepupae new
20
white prepupae 12hr
19
white prepupae 24hr
20
pupae 2d postWPP
13
pupae 3d postWPP
9
pupae 4d postWPP
10
adult male 01day
12
adult male 05day
15
adult male 30day
13
adult female 01day
22
adult female 05day
30
adult female 30day
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
(45)
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
(38)
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
(41)
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
(30)
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
(33)
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
(45)
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
(38)
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
(41)
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
(33)
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
26
Schneider line 2 Sg4
24
embryonic 1182-4H
19
embryonic GM2
13
embryonic Kc167
15
embryonic S1
45
embryonic S3
15
leg disc CME L1
25
wing disc CME-W2
12
wing disc ML-DmD8
14
wing disc ML-DmD9
21
wing disc ML-DmD16-c3
21
wing disc ML-DmD21
38
wing disc ML-DmD32
18
haltere disc ML-DmD17-c3
41
eye-antennal disc ML-DmD11
25
antennal disc ML-DmD20-c5
30
mixed discs ML-DmD4-c1
19
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
15
tumorous blood cells mbn2
7
ovary fGS/OSS
33
ovary OSC
17
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
11
cold shock, 4-day adult
6
heat shock, 4-day adult
11
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
10
Cadmium 100 mM 48 hrs, 4-day adult
12
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
6
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
5
Ethanol 2.5% 3 hrs, larvae L3
17
Ethanol 5% 3 hrs, larvae L3
7
Ethanol 10% 3 hrs, larvae L3
9
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
12
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
12
Paraquat 10 mM 48 hrs, 4-day adult
15
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
8
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 5 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 12 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs characterization construct
Insertions insertion of enhancer trap
insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 11 unique terms ) Terms Based on
Experimental Evidence ( 11 terms ) Molecular Function inferred from direct assay
Biological Process inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component inferred from direct assay
inferred from direct assay
inferred from direct assay
Terms Based on Predictions or
Assertions ( 0 terms ) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (43)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6ZGPZF )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG69CQHG )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG66Q5PB )
Apis mellifera
Western honey bee
Amel\Dcp1
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG010108
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH19427
Atta cephalotes
Leafcutter ant
Acep\ACEP27905
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO22348
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL16258
Linepithema humile
Argentine ant
Lhum\LH10898
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB20867
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG679CPV )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6QP0Q3 )
Caenorhabditis elegans
Nematode
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 6 )Bloomington Kyoto VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 75 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: Dcp1 CG11183
Source for database merge of Source for merge of: CG11183 anon-WO0118547.163
Additional comments Source for merge of CG11183 anon-WO0118547.163 was sequence comparison (date:051113).
Other Comments dsRNA made from templates generated with primers directed against this gene is transfected into S2 cells to study the genes role in decapping.
Dcp1 is required for degradation of
osk ,
bcd and
twe mRNAs during embryogenesis.
Dcp1 is required for the posterior localization of
osk mRNA in the oocyte.
dsRNA has been made from templates generated with primers directed against this gene.
In contrast to the decapping enzymes in yeast and humans, the
Dcp1 product does not seem to participate in the nonsense-mediated decay pathway.
Area matching Drosophila EST AI0643375.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 9 )Reported As Symbol Synonym Dcp1
(
Zaessinger et al., 2006 ,
Lindquist et al., 2011 ,
Hillebrand et al., 2010 ,
Barbee et al., 2006 ,
Lin et al., 2008 ,
Lauwers et al., 2009 ,
Snee and Macdonald, 2009 ,
Liu and Gall, 2007 ,
Olivieri et al., 2010 ,
Habermann et al., 2012 ,
Pressman et al., 2012 ,
Japanese National Institute of Genetics, 2012.5.21 )
DCP1
(
Rehwinkel et al., 2005 ,
Tritschler et al., 2007 ,
Eulalio et al., 2007 ,
Tritschler et al., 2009 ,
Jinek et al., 2008 ,
Eulalio et al., 2007 ,
Lee et al., 2009 ,
Tritschler et al., 2008 ,
Behm-Ansmant et al., 2006 ,
Farny et al., 2009 ,
Haas et al., 2010 ,
Jäger and Dorner, 2010 ,
Beerman and Jongens, 2011 ,
Miyoshi et al., 2009 )
dDcp1
(
Lin, 2006.2.28 ,
Lin et al., 2006 ,
Lin et al., 2004 ,
Seydoux and Braun, 2006 ,
Lin et al., 2006 ,
Lin et al., 2008 ,
Zabolotskaya et al., 2008 ,
Reich et al., 2009 ,
Lin et al., 2008 ,
Fan et al., 2011 )
Name Synonym Secondary FlyBase
IDs References ( 59 )Generate a list of List References by type
Recent research papers ( 6 )
Kibanov et al., 2013, Anal. Biochem. 436(1): 55--64Multicolor fluorescence imaging of whole-mount Drosophila testes for studying spermatogenesis. [FBrf0221049] Habermann et al., 2012, Mol. Cell. Biol. 32(17): 3554--3569Functional Analysis of Centrosomal Kinase Substrates in Drosophila melanogaster Reveals a New Function of the Nuclear Envelope Component Otefin in Cell Cycle Progression. [FBrf0219185] Pressman et al., 2012, G3 (Bethesda) 2(4): 437--448A Systematic Genetic Screen to Dissect the MicroRNA Pathway in Drosophila. [FBrf0218180] Beerman and Jongens, 2011, Neuroscience 181: 48--66A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms. [FBrf0213401] Fan et al., 2011, PLoS ONE 6(5): e20612Drosophila Ge-1 Promotes P Body Formation and oskar mRNA Localization. [FBrf0213914] Lindquist et al., 2011, Genome Res. 21(3): 433--446Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. [FBrf0213199]
Recent reviews (0)
All reviews listed in FlyBase were published before 2011