• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG3803

General Information
Symbol	Dmel\CG3803	Species	D. melanogaster
Name		Annotation symbol	CG3803
Feature type	protein_coding_gene	FlyBase ID	FBgn0034938
Gene Model Status	Current	Stock availability	10 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60A13-60A13	Sequence location	2R:19,840,036..19,841,562 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3803 (FBgn0034938). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity, acting on the CH-CH group of donors. Based on sequence similarity, it is predicted to be involved in the biological process: respiratory chain complex IV assembly. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Heme A synthase; Trypsin-like cysteine/serine peptidase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1626729_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3803. Gene sequence location is 2R:19840036..19841562.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60A13-60A13   Limits computationally determined from genome sequence between P{EP}TalEP489&P{EP}CG3065EP316 and P{lacW}Phmk07623&P{lacW}tsrk05633
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3803 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3803-RA FBtr0072208  NM_138011   1331   393
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3803-PA   FBpp0072117   44.4   393   10.68     NP_611855   AAF47112
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Heme A synthase (IPR003780) Trypsin-like cysteine/serine peptidase domain (IPR009003)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF47112   AY071468 AAL49090   BF506378   BG637264   BI243746   BI368683   BI640248   CO314584   CZ487332   CZ487333   EC054186   EC055618   EC055719   EC248734   GH739096   GH744392   GH745650   GH762301   GH763085   GH763325   GH765074   GH766198   GH768541   GH768655   GH769675
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W1F5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    143.175 Larval Midgut    93.5 Larval Hindgut    134.4 Larval Malpighian Tubules    174.9 Larval Fat Body    57.2 Larval Salivary Gland    160.1 Larval Trachea    93.425 Larval Carcass    65.35 Adult Head    88.3 Adult Eye    65.825 Adult Brain    189.5 Adult Thoracic-Abdominal Ganglion    250.9 Adult Crop    102.1 Adult Midgut    120.1 Adult Hindgut    119.7 Adult Malpighian Tubules    175.4 Adult Fat Body    67.4 Adult Salivary Gland    107.4 Adult Heart    80.4 Adult VirginFemale Spermatheca    82.6 Adult InseminatedFemale Spermatheca    95.1 Adult Ovary    142.3 Adult Testis    83.5 Adult Male Accessory Gland    74 Adult Carcass    67.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    88.3   NA  Eye    65.825   NA  Brain    189.5   143.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    250.9   NA  Crop    102.1   93.5  Midgut    120.1   134.4  Hindgut    119.7   174.9  Malpighian Tubules    175.4   57.2  Fat Body    67.4   160.1  Salivary Gland    107.4   NA  Heart    80.4   93.425  Trachea    NA   NA  VirginFemale Spermatheca    82.6   NA  InseminatedFemale Spermatheca    95.1   NA  Ovary    142.3   NA  Testis    83.5   NA  Male Accessory Gland    74   65.35  Carcass    67.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    5 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    4 head, mated 4-day female    2 head, mated 20-day female    3 head, mated 1-day male    7 head, mated 4-day male    5 head, mated 20-day male    8 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    5 digestive system, 4-day adult    5 digestive system, 20-day adult    5 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    3 ovary, virgin 4-day female    8 ovary, mated 4-day female    7 testis, mated 4-day male    11 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr  (29) embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2  (27) larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr  29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2  27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    18 embryo 02-04hr    10 embryo 04-06hr    19 embryo 06-08hr    21 embryo 08-10hr    21 embryo 10-12hr    23 embryo 12-14hr    20 embryo 14-16hr    24 embryo 16-18hr    29 embryo 18-20hr    24 embryo 20-22hr    15 embryo 22-24hr    16 larva L1    22 larva L2    27 larva L3 12hr old    18 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    11 white prepupae 24hr    12 pupae 2d postWPP    18 pupae 3d postWPP    20 pupae 4d postWPP    9 adult male 01day    10 adult male 05day    11 adult male 30day    10 adult female 01day    14 adult female 05day    15 adult female 30day    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (33) Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167  (32) embryonic S1  (37) embryonic S3    15 leg disc CME L1    22 wing disc CME-W2  (37) wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3  (35) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC  26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (33) Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167  32 embryonic S1  (37) embryonic S3    15 leg disc CME L1    22 wing disc CME-W2  (37) wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3  (35) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC  26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    33 Schneider line 2 Sg4    21 embryonic 1182-4H    10 embryonic GM2    20 embryonic Kc167    32 embryonic S1    37 embryonic S3    15 leg disc CME L1    22 wing disc CME-W2    37 wing disc ML-DmD8    13 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    11 wing disc ML-DmD21    11 wing disc ML-DmD32    12 haltere disc ML-DmD17-c3    35 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    17 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    21 tumorous blood cells mbn2    17 ovary fGS/OSS    16 ovary OSC    26 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    5 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    6 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    11 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034938 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3803-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG3803GD2191 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG3803 Class Mutagen Stocks Known lesion CG3803f04773 piggyBac transposase 3 -- CG3803c00529 1 --
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3803 Class Mutagen Stocks Known lesion CG3803GD2191 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803HMS01473 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803HMS02641 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803JF01523 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803JF01524 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803KK102813 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG3803NIG.3803R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG3803t7.9 in vitro construct - genomic fragment 0 Yes CG3803tH3 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6080 (Ryder, 2004.4.26) Df(2R)Exel7182 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2191} NA P{KK102813} NA P{NIG.3803R} NA P{TRiP.HMS01473} NA P{TRiP.HMS02641} NA P{TRiP.JF01523} NA P{TRiP.JF01524} NA characterization construct P{H3} NA P{thoc5+t7.9} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG3803c00529 NA PBac{WH}CG3803f04773 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
oxidoreductase activity, acting on the CH-CH group of donors inferred from electronic annotation with InterPro:IPR003780 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
heme a biosynthetic process inferred from electronic annotation with InterPro:IPR003780 (FlyBase Curators et al., 2004-) oxidation-reduction process inferred from electronic annotation with InterPro:IPR003780 (FlyBase Curators et al., 2004-) respiratory chain complex IV assembly inferred from sequence or structural similarity with Saccharomyces COX15 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
mitochondrial inner membrane inferred from sequence or structural similarity with Saccharomyces COX15 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3803 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0034938 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37809
Orthologs
OrthoDB Orthologs (39) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6256CP Dipteran inclusive ortholog search EOG6MKNQV Insect inclusive ortholog search EOG6TX9NB Arthropod inclusive ortholog search EOG6HMGRS Metazoa inclusive ortholog search EOG6V7B96
Orthologs in Drosophila Species (EOG6256CP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG3803     Drosophila simulans   Dsim\GD24990 Y   Drosophila sechellia   Dsec\GM15488 Y   Drosophila erecta   Dere\GG19975 Y   Drosophila yakuba   Dyak\GE11508 Y   Drosophila ananassae   Dana\GF12050 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17696 Y   Drosophila persimilis   Dper\GL10912 Y   Drosophila willistoni   Dwil\GK15851 Y   Drosophila virilis   Dvir\GJ20450 Y   Drosophila mojavensis   Dmoj\GI20711 Y   Drosophila grimshawi   Dgri\GH21698 Y
Orthologs in non-Drosophila Dipterans (EOG6MKNQV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012426   Anopheles gambiae Malaria mosquito  Agam\AGAP001744   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017747   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ016252
Orthologs in non-Dipteran Insects (EOG6TX9NB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50093   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037307   Acromyrmex echinatior Panamanian leafcutter ant  Aech\ctaA   Atta cephalotes Leafcutter ant  Acep\ctaA   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15048   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19336   Linepithema humile Argentine ant  Lhum\LH11469   Pogonomyrmex barbatus Red harvester ant  Pbar\PB22081   Solenopsis invicta Red fire ant  Sinv\SINV14392   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001211   Bombyx mori Silkmoth  Bmor\BGIBMGA001309   Pediculus humanus Human body louse  Phum\PHUM420670   Tribolium castaneum Red flour beetle  Tcas\TC000219
Orthologs in non-Insect Arthropods (EOG6HMGRS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Suclg2   Ixodes scapularis Deer tick  Isca\ISCW008438
Orthologs in non-Arthropod Metazoa (EOG6V7B96)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\T06D8.5   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015238gn   Danio rerio Zebrafish  Drer\cox15   Xenopus tropicalis Western clawed frog  Xtro\cox15   Gallus gallus Domestic chicken  Ggal\COX15   Mus musculus House mouse  Mmus\Cox15   Rattus norvegicus Norway rat  Rnor\Cox15   Homo sapiens Human  Hsap\ENSG00000014919
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000014919
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24990 Drosophila sechellia Dsec\GM15488 Drosophila erecta Dere\GG19975 Drosophila yakuba Dyak\GE11508 Drosophila ananassae Dana\GF12050 Drosophila pseudoobscura pseudoobscura Dpse\GA17696 Drosophila persimilis Dper\GL10912 Drosophila willistoni Dwil\GK15851 Drosophila virilis Dvir\GJ20450 Drosophila mojavensis Dmoj\GI20711 Drosophila grimshawi Dgri\GH21698
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	31073 y1 v1; P{TRiP.JF01524}attP2 18804 w1118; PBac{WH}CG3803f04773/CyO 35731 y1 sc* v1; P{TRiP.HMS01473}attP2 42948 y1 sc* v1; P{TRiP.HMS02641}attP40 31072 y1 v1; P{TRiP.JF01523}attP2/TM3, Ser1
Harvard	- PBac{PB}CG3803c00529 - PBac{WH}CG3803f04773
Kyoto	114659 yd2 w1118 P{ey-FLP.N}2; P{neoFRT}42D PBac{WH}CG3803f04773 /CyO y+
VDRC	v105443 P{KK102813}VIE-260B v3596 w1118; P{GD2191}v3596
Genomic Clones ( 1 )
	BACR28M05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 21 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE54691
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08829 RE41468 SD15172 SD23059
Other clones	117973 EC054186 EC055618 EC055719 EK237062 RP001009103 RP001012120 RP001019638 RP001022492 RP001024696 RP001025248 RP001038960 RP001039848 RP001041069 RP001044233 RP001045408
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034938 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37809
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138011 RefSeq (Proteins) • NP_611855 DDBJ / EMBL / GenBank • AAF47112 AAL49090 AY071468 BI368683 CZ487332 CZ487333 Entrez Gene - A searchable database of RefSeq genes. • 37809 UniProtKB/TrEMBL • Q9W1F5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Heme A synthase (IPR003780) Trypsin-like cysteine/serine peptidase domain (IPR009003)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0034938 DRSC - Results from RNAi screens. • FBgn0034938 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034938 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3803-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034938 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37809 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37809 modMine - Data generated by the modENCODE project. • FBgn0034938
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG3803 (Moon et al., 2011, Keleman et al., 2009.8.5, Ni et al., 2008, Porcelli et al., 2010, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 19 )
Research paper	Moon et al., 2011, Development 138(17): 3835--3845 The THO complex is required for nucleolar integrity in Drosophila spermatocytes. [FBrf0214600] Porcelli et al., 2010, Mitochondrion 10(5): 433--448 Genetic, functional and evolutionary characterization of scox, the Drosophila melanogaster ortholog of the human SCO1 gene. [FBrf0211481] Ni et al., 2008, Nat. Methods 5(1): 49--51 Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. [FBrf0200406]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]