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Gene Dmel\CG10904

General Information
Symbol	Dmel\CG10904	Species	D. melanogaster
Name		Annotation symbol	CG10904
Feature type	protein_coding_gene	FlyBase ID	FBgn0034945
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60A14-60A14	Sequence location	2R:19,856,584..19,857,592 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10904 (FBgn0034945). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: MADF domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval salivary gland, larval trachea, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1627154_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10904. Gene sequence location is 2R:19856584..19857592.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60A14-60A14   Limits computationally determined from genome sequence between P{EP}TalEP489&P{EP}CG3065EP316 and P{lacW}Phmk07623&P{lacW}tsrk05633
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10904 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10904-RA FBtr0072205  NM_138016   946   266
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10904-PA   FBpp0072114   30.7   266   7.42     NP_611860   AAF47121
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF47121   AI543391   AY071276 AAL48898   BI234913   BP540833   BP558243   BQ103010   CO307398   CO309138   CO328310   EC075004   EC203628   EC215135   EC258821   EV591087   EV597842   FE863455   FE863559   FE863870   FE863943   FE863972   GH739523   GH744984   GH745786   GH769123
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W1E7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval salivary gland, larval trachea, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    146.725 Larval Midgut    57.8 Larval Hindgut    71.9 Larval Malpighian Tubules    95.9 Larval Fat Body    75.8 Larval Salivary Gland    109 Larval Trachea    158.125 Larval Carcass    64.15 Adult Head    80.4 Adult Eye    112.1 Adult Brain    126.7 Adult Thoracic-Abdominal Ganglion    100.9 Adult Crop    120.9 Adult Midgut    87.4 Adult Hindgut    78.3 Adult Malpighian Tubules    70.7 Adult Fat Body    64.2 Adult Salivary Gland    94 Adult Heart    81.75 Adult VirginFemale Spermatheca    48.9 Adult InseminatedFemale Spermatheca    54.7 Adult Ovary    193.6 Adult Testis    35.9 Adult Male Accessory Gland    96 Adult Carcass    63 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    80.4   NA  Eye    112.1   NA  Brain    126.7   146.725  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    100.9   NA  Crop    120.9   57.8  Midgut    87.4   71.9  Hindgut    78.3   95.9  Malpighian Tubules    70.7   75.8  Fat Body    64.2   109  Salivary Gland    94   NA  Heart    81.75   158.125  Trachea    NA   NA  VirginFemale Spermatheca    48.9   NA  InseminatedFemale Spermatheca    54.7   NA  Ovary    193.6   NA  Testis    35.9   NA  Male Accessory Gland    96   64.15  Carcass    63 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8  (28) carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (42) testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8  28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female  (54) ovary, mated 4-day female  (42) testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    14 central nervous system, larvae L3    25 central nervous system, pupae P8    16 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    10 head, mated 1-day female    14 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    11 head, mated 4-day male    16 head, mated 20-day male    20 salivary gland, larvae L3 wandering    8 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    28 carcass, larvae L3 wandering    22 carcass, 1-day adult    9 carcass, 4-day adult    12 carcass, 20-day adult    11 ovary, virgin 4-day female    54 ovary, mated 4-day female    42 testis, mated 4-day male    14 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (28) embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr  (29) embryo 08-10hr  (29) embryo 10-12hr  (27) embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr  29 embryo 08-10hr  29 embryo 10-12hr  27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    24 embryo 04-06hr    22 embryo 06-08hr    29 embryo 08-10hr    29 embryo 10-12hr    27 embryo 12-14hr    21 embryo 14-16hr    13 embryo 16-18hr    13 embryo 18-20hr    9 embryo 20-22hr    8 embryo 22-24hr    11 larva L1    6 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    16 white prepupae new    14 white prepupae 12hr    14 white prepupae 24hr    16 pupae 2d postWPP    13 pupae 3d postWPP    10 pupae 4d postWPP    5 adult male 01day    7 adult male 05day    7 adult male 30day    7 adult female 01day    9 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (59) Schneider line 2 Sg4    23 embryonic 1182-4H  (31) embryonic GM2  (29) embryonic Kc167  (48) embryonic S1  (48) embryonic S3    24 leg disc CME L1  (34) wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9  (33) wing disc ML-DmD16-c3  (31) wing disc ML-DmD21  (35) wing disc ML-DmD32  (29) haltere disc ML-DmD17-c3  (60) eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  (31) CNS ML-DmBG1-c1  (38) CNS ML-DmBG2-c2  (32) tumorous blood cells mbn2    16 ovary fGS/OSS  (43) ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (59) Schneider line 2 Sg4    23 embryonic 1182-4H  31 embryonic GM2  29 embryonic Kc167  (48) embryonic S1  (48) embryonic S3    24 leg disc CME L1  (34) wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9  (33) wing disc ML-DmD16-c3  31 wing disc ML-DmD21  (35) wing disc ML-DmD32  29 haltere disc ML-DmD17-c3  (60) eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  31 CNS ML-DmBG1-c1  (38) CNS ML-DmBG2-c2  32 tumorous blood cells mbn2    16 ovary fGS/OSS  (43) ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    59 Schneider line 2 Sg4    23 embryonic 1182-4H    31 embryonic GM2    29 embryonic Kc167    48 embryonic S1    48 embryonic S3    24 leg disc CME L1    34 wing disc CME-W2    22 wing disc ML-DmD8    21 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    31 wing disc ML-DmD21    35 wing disc ML-DmD32    29 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    31 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    16 ovary fGS/OSS    43 ovary OSC    21 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult  (30) Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult  30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    10 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    16 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    24 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    12 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	BDGP expression data • RE30687 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034945 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10904-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG10904GD7120 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG10904 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10904 Class Mutagen Stocks Known lesion CG10904GD7120 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10904NIG.10904R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(2R)Alas3b (Shaik et al., 2012)
Disrupted in	Df(2R)Exel6080 (Ryder, 2004.4.26) Df(2R)Exel7182 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7120} NA P{NIG.10904R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG10904 - CkIIβ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10904 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63405 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034945 DroID - A comprehensive database of gene and protein interactions. • FBgn0034945 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37817
Orthologs
OrthoDB Orthologs (21) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG64F6WD Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6M64FQ Arthropod inclusive ortholog search EOG6M908M Metazoa inclusive ortholog search EOG6038P1
Orthologs in Drosophila Species (EOG64F6WD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG10904     Drosophila simulans   Dsim\GD24988 Y   Drosophila sechellia   Dsec\GM15485 Y   Drosophila erecta   Dere\GG19972 Y   Drosophila yakuba   Dyak\GE11504 Y   Drosophila ananassae   Dana\GF12047 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10629 Y   Drosophila persimilis   Dper\GL10439 Y   Drosophila willistoni   Dwil\GK15847 Y   Drosophila virilis   Dvir\GJ19741 Y   Drosophila mojavensis   Dmoj\GI20688 Y   Drosophila grimshawi   Dgri\GH20177 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6M64FQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50288 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO12798 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000428 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI48628 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI54894 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006954 Y Tribolium castaneum Red flour beetle  Tcas\TC003869 Y
Orthologs in non-Insect Arthropods (EOG6M908M)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW015773 Y
Orthologs in non-Arthropod Metazoa (EOG6038P1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028165gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24988 Drosophila sechellia Dsec\GM15485 Drosophila erecta Dere\GG19972 Drosophila yakuba Dyak\GE11504 Drosophila ananassae Dana\GF12047 Drosophila pseudoobscura pseudoobscura Dpse\GA10629 Drosophila persimilis Dper\GL10439 Drosophila willistoni Dwil\GK15847 Drosophila virilis Dvir\GJ19741 Drosophila mojavensis Dmoj\GI20688 Drosophila grimshawi Dgri\GH20177
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v38415 w1118; P{GD7120}v38415/TM3 v38416 w1118; P{GD7120}v38416/TM3
Genomic Clones ( 1 )
	BACR28M05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 24 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE30687
Other clones	DPiM_RE30687
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	70723 149176 157174 214563.71 Dmel_neb_012255_0356_2079 Dmel_neb_012368_0907_2870 EK254511 EK260415 EP08939 FGA008C06 FGM313H04 RM07495 RM07795 RM07995 RM08095 RM08195 RP001014413 RP001029714 RP001033945 RP001042759 SD10130 UUGC0406
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0034945 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37817
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138016 RefSeq (Proteins) • NP_611860 DDBJ / EMBL / GenBank • AAF47121 AAL48898 AY071276 BI234913 Entrez Gene - A searchable database of RefSeq genes. • 37817 UniProtKB/TrEMBL • Q9W1E7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE30687
Linkouts
	BioGRID - A database of protein and genetic interactions • 63405 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0034945 DroID - A comprehensive database of gene and protein interactions. • FBgn0034945 DRSC - Results from RNAi screens. • FBgn0034945 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0034945 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10904-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0034945 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37817 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37817 modMine - Data generated by the modENCODE project. • FBgn0034945
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10904 (Shaik et al., 2012, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Shaik et al., 2012, Europ. J. Cell Biol. 91(3): 204--215 δ-Aminolevulinate synthase is required for apical transcellular barrier formation in the skin of the Drosophila larva. [FBrf0217466] Kashevsky et al., 2002, Proc. Natl. Acad. Sci. U.S.A. 99(17): 11217--11222 The anaphase promoting complex/cyclosome is required during development for modified cell cycles. [FBrf0152304]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]