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Gene Dmel\CG6845

General Information
Symbol	Dmel\CG6845	Species	D. melanogaster
Name		Annotation symbol	CG6845
Feature type	protein_coding_gene	FlyBase ID	FBgn0035099
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	61B1-61B1	Sequence location	3L:146,433..149,056 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6845 (FBgn0035099). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Dendritic cell-specific transmembrane protein-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1630763_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG6845. Gene sequence location is 3L:146433..149056.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 61B1-61B1   Limits computationally determined from genome sequence between P{PZ}trh10512 and P{EP}EP3104EP3104
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6845 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated. DGC clone GH26634 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6845-RC FBtr0273351  NM_138156   2176   672 CG6845-RD FBtr0273352  NM_001144386   1069   303 CG6845-RE FBtr0273353  NM_001144387   2294   334
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6845-PC   FBpp0271859   77.0   672   8.52     NP_612000   AAF47333 CG6845-PD   FBpp0271860   34.2   303   8.84     NP_001137858   ACL83214 CG6845-PE   FBpp0271861   38.8   334   8.41     NP_001137859   ACL83215
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Dendritic cell-specific transmembrane protein-like (IPR012858)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA817175   AE014296 AAF47333   AE014296 ACL83214   AE014296 ACL83215   AI455258   AI513512   AI946065   AW941898   AY051619 AAK93043   BF490869   BG637329   BT003264 AAO25021   BT012492   CO188327   CO301422   EC062772
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q961F6 Q9W0V0 B7Z0G8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    104.35 Larval Midgut    35.8 Larval Hindgut    41.6 Larval Malpighian Tubules    85.2 Larval Fat Body    79.1 Larval Salivary Gland    133.4 Larval Trachea    146.975 Larval Carcass    37.4 Adult Head    11.9 Adult Eye    23.4 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    60.6 Adult Crop    36.4 Adult Midgut    77.5 Adult Hindgut    56.9 Adult Malpighian Tubules    84.3 Adult Fat Body    30.9 Adult Salivary Gland    82 Adult Heart    27.275 Adult VirginFemale Spermatheca    45.4 Adult InseminatedFemale Spermatheca    53.7 Adult Ovary    30.5 Adult Testis    53.6 Adult Male Accessory Gland    38.8 Adult Carcass    28.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    23.4   NA  Brain    18.2   104.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    60.6   NA  Crop    36.4   35.8  Midgut    77.5   41.6  Hindgut    56.9   85.2  Malpighian Tubules    84.3   79.1  Fat Body    30.9   133.4  Salivary Gland    82   NA  Heart    27.275   146.975  Trachea    NA   NA  VirginFemale Spermatheca    45.4   NA  InseminatedFemale Spermatheca    53.7   NA  Ovary    30.5   NA  Testis    53.6   NA  Male Accessory Gland    38.8   37.4  Carcass    28.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    7 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    3 head, mated 20-day male    3 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    2 fat body, white prepupae    3 fat body, pupae P8    9 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    2 ovary, mated 4-day female    2 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    13 embryo 06-08hr    14 embryo 08-10hr    15 embryo 10-12hr    7 embryo 12-14hr    5 embryo 14-16hr    2 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    2 larva L2    5 larva L3 12hr old    5 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    17 white prepupae new    13 white prepupae 12hr    18 white prepupae 24hr    16 pupae 2d postWPP    9 pupae 3d postWPP    4 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    6 adult male 30day    6 adult female 01day    4 adult female 05day    6 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2  (53) embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2  (32) wing disc ML-DmD8  (31) wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1  (27) CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2  (53) embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2  32 wing disc ML-DmD8  31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1  27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    13 embryonic 1182-4H    21 embryonic GM2    53 embryonic Kc167    22 embryonic S1    25 embryonic S3    23 leg disc CME L1    8 wing disc CME-W2    32 wing disc ML-DmD8    31 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    12 wing disc ML-DmD32    6 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    9 ovary fGS/OSS    18 ovary OSC    13 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035099 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6845-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG6845 Class Mutagen Stocks Known lesion CG6845MB03988 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6845 Class Mutagen Stocks Known lesion CG6845KK101482 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6845GD14608 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG6845GD528 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6083 (Ryder, 2004.4.26, Tikhmyanova et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD528} NA P{GD14608} NA P{KK101482} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG6845MB03988 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR012858 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6845 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63583 DroID - A comprehensive database of gene and protein interactions. • FBgn0035099 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38019
Orthologs
OrthoDB Orthologs (50) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6MCXK9 Dipteran inclusive ortholog search EOG6CC48Z Insect inclusive ortholog search EOG6KWHNP Arthropod inclusive ortholog search EOG6X95Z3, EOG6QBZMN Metazoa inclusive ortholog search EOG644ZC7
Orthologs in Drosophila Species (EOG6MCXK9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG6845     Drosophila simulans   Dsim\GD13546 Y   Drosophila sechellia   Dsec\GM14310 Y   Drosophila erecta   Dere\GG14692 Y   Drosophila yakuba   Dyak\GE21054 Y   Drosophila ananassae   Dana\GF24881 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA25497     Drosophila persimilis   Dper\GL14510     Drosophila persimilis   Dper\GL10060     Drosophila persimilis   Dper\GL16050     Drosophila willistoni   Dwil\GK21036     Drosophila virilis   Dvir\GJ12498 Y   Drosophila mojavensis   Dmoj\GI16754 Y   Drosophila grimshawi   Dgri\GH15478 Y
Orthologs in non-Drosophila Dipterans (EOG6CC48Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006732   Anopheles gambiae Malaria mosquito  Agam\AGAP005412   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ016034
Orthologs in non-Dipteran Insects (EOG6KWHNP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54633   Apis mellifera Western honey bee  Amel\GB50653   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006418   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21566   Atta cephalotes Leafcutter ant  Acep\ACEP15332   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14583   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18685   Linepithema humile Argentine ant  Lhum\LH11764   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12765   Solenopsis invicta Red fire ant  Sinv\SINV15895   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004002   Pediculus humanus Human body louse  Phum\PHUM497890   Pediculus humanus Human body louse  Phum\PHUM293200   Tribolium castaneum Red flour beetle  Tcas\TC008759
Orthologs in non-Insect Arthropods (EOG6X95Z3, EOG6QBZMN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW011721
Orthologs in non-Arthropod Metazoa (EOG644ZC7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\spe-42 Y Caenorhabditis elegans Nematode  Cele\K12B6.2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015352gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026909gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015353gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005390gn Y Danio rerio Zebrafish  Drer\dcst2 Y Danio rerio Zebrafish  Drer\dcst1 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031693 Y Xenopus tropicalis Western clawed frog  Xtro\dcst2 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000005468 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000012168 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000030491 Y Mus musculus House mouse  Mmus\Dcst1 Y Rattus norvegicus Norway rat  Rnor\Dcst1 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000043206 Y Homo sapiens Human  Hsap\ENSG00000163354 Y Homo sapiens Human  Hsap\DCST1 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\ENSG00000163354     Hsap\DCST1
AAA Orthologs (8) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13546 Drosophila sechellia Dsec\GM14310 Drosophila erecta Dere\GG14692 Drosophila yakuba Dyak\GE21054 Drosophila ananassae Dana\GF24881 Drosophila virilis Dvir\GJ12498 Drosophila mojavensis Dmoj\GI16754 Drosophila grimshawi Dgri\GH15478
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	24555 w1118; Mi{ET1}CG6845MB03988
VDRC	v107719 P{KK101482}VIE-260B
Genomic Clones ( 2 )
	BACR11J11 BACR45O17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 9 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH26634 LD03460 LD22345
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT27485 SD15250
Other clones	58486 bs20d09 EK039225 EK180927
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035099 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38019
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG6845 BEST:LD22345 (Rana, 2004.7.8)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138156 NM_001144386 NM_001144387 RefSeq (Proteins) • NP_612000 NP_001137858 NP_001137859 DDBJ / EMBL / GenBank • AA817175 AAF47333 AAK93043 AAO25021 ACL83214 ACL83215 AI455258 AI513512 AW941898 AY051619 BT003264 Entrez Gene - A searchable database of RefSeq genes. • 38019 UniProtKB/TrEMBL • B7Z0G8 Q9W0V0 Q961F6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Dendritic cell-specific transmembrane protein-like (IPR012858)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63583 DroID - A comprehensive database of gene and protein interactions. • FBgn0035099 DRSC - Results from RNAi screens. • FBgn0035099 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035099 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6845-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035099 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38019 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38019 modMine - Data generated by the modENCODE project. • FBgn0035099
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BEST:LD22345   CG6845 (Keleman et al., 2009.8.5, Tikhmyanova et al., 2010)
Name Synonym
Secondary FlyBase IDs
	FBgn0046266
References ( 14 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Tikhmyanova et al., 2010, PLoS ONE 5(8): e12369 Dcas supports cell polarization and cell-cell adhesion complexes in development. [FBrf0211678] Dimova et al., 2003, Genes Dev. 17(18): 2308--2320 Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. [FBrf0162136]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Bellen, 2007.10.9, batch761.xml batch761.xml [FBrf0200260] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Rana, 2004.7.8, BLAST analysis. BLAST analysis. [FBrf0178762] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Oliver, 2001.8.16, Genome Res.: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]